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Mong-Hong Lee
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Journal Articles

CSN6 Mediates Nucleotide Metabolism to Promote Tumor Development and Chemoresistance in Colorectal Cancer

Shaomin Zou, Baifu Qin, Ziqing Yang, Wencong Wang, Jieping Zhang, Yijing Zhang, Manqi Meng, Junyan Feng, Yunling Xie, Ling Fang, Lishi Xiao, Peng Zhang, Xiangqi Meng, Hyun Ho Choi, Weijie Wen, Qihao Pan, Bart Ghesquière, Ping Lan, Mong-Hong Lee, Lekun Fang
Journal: Cancer Research
Cancer Res (2023) 83 (3): 414–427.
https://doi.org/10.1158/0008-5472.CAN-22-2145
Published: 03 February 2023
View article titled, CSN6 Mediates Nucleotide Metabolism to Promote Tumor Development and Chemoresistance in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract B20: Obesity-induced Nlrc4 inflammasome promotes angiogenesis in breast cancer

Ryan Kolb, Liem Phan, Nicholas Borcherding, Yinghong Liu, Fang Yuan, Ann M. Janowski, Qing Xie, Kathleen R. Markan, Wei Li, Matthew J. Potthoff, Enrique Fuentes-Mattei, Leslie G. Ellies, Michael Knudson, Mong-Hong Lee, Sai-Ching Jim Yeung, Suzanne L. Cassel, Fayyaz S. Sutterwala, Weizhou Zhang
Journal: Cancer Research
Cancer Res (2016) 76 (15_Supplement): B20.
https://doi.org/10.1158/1538-7445.TME16-B20
Published: 28 July 2016
View article titled, Abstract B20: Obesity-induced Nlrc4 inflammasome promotes angiogenesis in breast cancer
Journal Articles

Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors

James A. Bankson, Christopher M. Walker, Marc S. Ramirez, Wolfgang Stefan, David Fuentes, Matthew E. Merritt, Jaehyuk Lee, Vlad C. Sandulache, Yunyun Chen, Liem Phan, Ping-Chieh Chou, Arvind Rao, Sai-Ching J. Yeung, Mong-Hong Lee, Dawid Schellingerhout, Charles A. Conrad, Craig Malloy, A. Dean Sherry, Stephen Y. Lai, John D. Hazle
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (22): 4708–4717.
https://doi.org/10.1158/0008-5472.CAN-15-0171
Published: 15 November 2015
View article titled, Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-<sup>13</sup>C]-Pyruvate Offers Improved Metabolic Imaging of Tumors
Open the PDF for Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-<sup>13</sup>C]-Pyruvate Offers Improved Metabolic Imaging of Tumors in another window
Includes: Supplementary data
Journal Articles

Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma

Liem M. Phan, Enrique Fuentes-Mattei, Weixin Wu, Guermarie Velazquez-Torres, Kanishka Sircar, Christopher G. Wood, Tao Hai, Camilo Jimenez, Gilbert J. Cote, Levent Ozsari, Marie-Claude Hofmann, Siyuan Zheng, Roeland Verhaak, Lance Pagliaro, Maria Angelica Cortez, Mong-Hong Lee, Sai-Ching J. Yeung, Mouhammed Amir Habra
Journal: Cancer Research
Cancer Res (2015) 75 (19): 4131–4142.
https://doi.org/10.1158/0008-5472.CAN-14-3707
Published: 30 September 2015
View article titled, Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma
Open the PDF for Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1922: Target mutation comparasion of WGA circulating tumor cell and primary tumor in epithelial ovarian cancer cell line using NGS

Pi-Lin Sung, Chi-Ying F. Huang, Michael Hsiao, Kuo-Chang Wen, Ming-Shyen Yen, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1922.
https://doi.org/10.1158/1538-7445.AM2015-1922
Published: 01 August 2015
View article titled, Abstract 1922: Target mutation comparasion of WGA circulating tumor cell and primary tumor in epithelial ovarian cancer cell line using NGS
Journal Articles

Abstract 5171: EpCAM expression governs tumor growth or distant metastasis of human endometrial cancer: grow or go theory

Kuo-Chang Wen, Peng-Hui Wang, Pi-Lin Sung, Mong-Hong Lee, Cheng-Wen Wu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5171.
https://doi.org/10.1158/1538-7445.AM2015-5171
Published: 01 August 2015
View article titled, Abstract 5171: EpCAM expression governs tumor growth or distant metastasis of human endometrial cancer: grow or go theory
Journal Articles

Abstract 3927: Obesity induces changes in adipokines profile and activates Akt/mTOR signaling accelerating breast carcinogenesis and tumor growth

Enrique Fuentes-Mattei, Guermarie Velazquez-Torres, Liem Phan, Fanmao Zhang, Ping-Chieh Chou, Ji-Hyun Shin, Hyun-Ho Choi, Jiun-Sheng Chen, Ruiying Zhao, Jian Chen, Chris Gully, Colin Carlock, Yuan Qi, Ya Zhang, Yun Wu, Francisco Esteva, Yongde Luo, Wallace L. McKeehan, Joe E. Ensor, Gabriel N. Hortobagyi, Lajos Pusztai Pusztai, W. Fraser Symmans, Mong-Hong Lee, Sai-Ching J. Yeung
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3927.
https://doi.org/10.1158/1538-7445.AM2014-3927
Published: 01 October 2014
View article titled, Abstract 3927: Obesity induces changes in adipokines profile and activates Akt/mTOR signaling accelerating breast carcinogenesis and tumor growth
Journal Articles

Abstract 2046: TGF-β drives tumor-progression via JAK/STAT3-signaling in advanced HCC.

Andres Rojas, Jessica Cromheecke, Mong-Hong Lee, Mien-Chie Hung, Boris Blechacz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2046.
https://doi.org/10.1158/1538-7445.AM2013-2046
Published: 15 April 2013
View article titled, Abstract 2046: TGF-β drives tumor-progression via JAK/STAT3-signaling in advanced HCC.
Journal Articles

Abstract LB-283: Aurora B binds p53 during both interphase and mitosis, phosphorylates it and promotes its degradation

Enrique Fuentes-Mattei, Christopher Gully, Guermarie Velazquez-Torres, Ji-Hyun Shin, Jiun-Sheng Chen, Hyun Ho Choi, Ping-Chieh Chou, Henry P. Adams, Liem Phan, Tsung-Ying Yang, Sai-Ching J. Yeung, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-283.
https://doi.org/10.1158/1538-7445.AM2012-LB-283
Published: 15 April 2012
View article titled, Abstract LB-283: Aurora B binds p53 during both interphase and mitosis, phosphorylates it and promotes its degradation
Journal Articles

14-3-3σ Exerts Tumor-Suppressor Activity Mediated by Regulation of COP1 Stability

Chun-Hui Su, Ruiying Zhao, Fanmao Zhang, Changju Qu, Bo Chen, Yin-Hsun Feng, Liem Phan, Jian Chen, Hua Wang, Huamin Wang, Sai-Ching J. Yeung, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2011) 71 (3): 884–894.
https://doi.org/10.1158/0008-5472.CAN-10-2518
Published: 01 February 2011
View article titled, 14-3-3σ Exerts Tumor-Suppressor Activity Mediated by Regulation of COP1 Stability
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Includes: Supplementary data
Journal Articles

Abstract 457: Hypoxia-mediated upregulation of Pim-1 contributes to tumor survival

Jian Chen, Masanobu Kobayashi, Stephanie Darmanin, Yi Qiao, Christopher Gully, Ruiying Zhao, Satoshi Kondo, Hua Wang, Huamin Wang, Sai-Ching Jim Yeung, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 457.
https://doi.org/10.1158/1538-7445.AM10-457
Published: 15 April 2010
View article titled, Abstract 457: Hypoxia-mediated upregulation of Pim-1 contributes to tumor survival
Journal Articles

Abstract #2938: Treatment for diabetes mellitus-2 could prevent pancreatic cancer cell growth

Guermarie Velázquez-Torres, Christopher Gully, Liem Phan, Sai-Ching Yeung, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2938.
Published: 01 May 2009
View article titled, Abstract #2938: Treatment for diabetes mellitus-2 could prevent pancreatic cancer cell growth
Journal Articles

Abstract #3726: Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

Christopher Gully, Jian Chen, Fanmao Zhang, James Yeung, Sai-Ching Jim Yeung, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3726.
Published: 01 May 2009
View article titled, Abstract #3726: Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer
Journal Articles

Ubiquitination-mediated p57Kip2 degradation by CSN5-Skp2 confers cancer development

Ruiying Zhao, Jian Chen, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2594.
Published: 01 May 2008
View article titled, Ubiquitination-mediated p57<sup>Kip2</sup> degradation by CSN5-Skp2 confers cancer development
Journal Articles

Tumor suppressive activity of CDK inhibitor p57Kip2 in HER2/neu-overexpressing breast cancer cells

Ruiying Zhao, Ting-Fan Che, Yu-Li Lin, Yujian Zhang, Heng-Yin Yang, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 361.
Published: 15 April 2006
View article titled, Tumor suppressive activity of CDK inhibitor p57Kip2 in HER2/neu-overexpressing breast cancer cells
Journal Articles

14-3-3 sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma

Huiling Yang, Ruiying Zhao, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1155.
Published: 15 April 2006
View article titled, 14-3-3 sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma
Journal Articles

DNA Damage–Induced Protein 14-3-3 σ Inhibits Protein Kinase B/Akt Activation and Suppresses Akt-Activated Cancer

Huiling Yang, Yu-Ye Wen, Ruiying Zhao, Yu-Li Lin, Keith Fournier, Heng-Yin Yang, Yun Qiu, Jose Diaz, Christine Laronga, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3096–3105.
https://doi.org/10.1158/0008-5472.CAN-05-3620
Published: 15 March 2006
View article titled, DNA Damage–Induced Protein 14-3-3 σ Inhibits Protein Kinase B/Akt Activation and Suppresses Akt-Activated Cancer
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Journal Articles

Constitutively active FOXO4 can regulate p27 Kip1 post-transcriptionally and suppresses HER2-mediated tumorigenicity

Mong-Hong Lee, Huiling Yang, Ruiying Zhao, Heng-Yin Yang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1310.
Published: 01 May 2005
View article titled, Constitutively active FOXO4 can regulate p27 Kip1 post-transcriptionally and suppresses HER2-mediated tumorigenicity
Journal Articles

Growth arrest induced by anti-HER2 antibody blocks breast cancer cells in the late G1 phase of the cell cycle

Xiao-Feng Le, Weiqun Mao, Isabelle Bedrosian, Xianfeng Wen, Mollianne Murray, Khandan Keyomarsi, Mong-Hong Lee, Robert C. Bast, Jr.
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 533.
Published: 01 May 2005
View article titled, Growth arrest induced by anti-HER2 antibody blocks breast cancer cells in the late G1 phase of the cell cycle
Journal Articles

14-3-3 sigma is a positive regulator of p53 and suppresses tumor growth

Heng-Yin Yang, Yu-Ye Wen, Chi-Hsing Chen, Guillermina Lozano, Mong-Hong Lee
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 975.
Published: 01 April 2004
View article titled, 14-3-3 sigma is a positive regulator of p53 and suppresses tumor growth