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Mohit Kumar Jolly
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Journal Articles

Abstract 7376: Modeling the dynamics of lung cancer cells along the epithelial−mesenchymal spectrum in the stem and non-stem cell compartments

Arianna Di Bernardo, Sarthak Sahoo, Melissa Balsamo, Elsa Quaranta, Mohit Kumar Jolly, Giulia Bertolini, Luca Roz
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7376.
https://doi.org/10.1158/1538-7445.AM2024-7376
Published: 22 March 2024
View articletitled, Abstract 7376: Modeling the dynamics of lung cancer cells along the epithelial−mesenchymal spectrum in the stem and non-stem cell compartments
Journal Articles

Abstract A019: Development of adaptive anoikis resistance promotes ovarian cancer metastasis that can be prevented by CDK8/19 Mediator kinase inhibition

Mehri Monavarian, Resha Rajkarnikar, Emily Faith Page, Asha Kumari, Liz Macias Quintero, Lara Ianov, sarthak Sahoo, Mohit Kumar Jolly, Elizabeth Worthey, Nadine Hempel, Abhyudai Singh, Eugenia Broude, Karthikeyan Mythreye
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A019.
https://doi.org/10.1158/1538-7445.OVARIAN23-A019
Published: 04 March 2024
View articletitled, Abstract A019: Development of adaptive anoikis resistance promotes ovarian cancer metastasis that can be prevented by CDK8/19 Mediator kinase inhibition
Journal Articles

Abstract B019: A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer

Kathryn E. Ware, Beatrice C. Thomas, Pelumi Olawuni, Maya U. Sheth, Nathan Hawkey, Yeshwanth M, Brian C. Miller, Katherine J. Vietor, Mohit Kumar Jolly, So Young Kim, Andrew J. Armstrong, Jason A. Somarelli
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B019.
https://doi.org/10.1158/1538-7445.PRCA2023-B019
Published: 02 June 2023
View articletitled, Abstract B019: A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer
Journal Articles

Abstract 5828: Distinct immunosuppressive tumor microenvironment modulates small cell lung carcinoma neuroendocrine phenotypic plasticity and heterogeneity

Parth Anil Desai, Nobuyuki Takahashi, Yingying Cao, Christopher Schultz, Darryl Nousome, Desiree Tillo, Lakshya Chauhan, Mayank tandon, Rajesh kumar Bhardwaj, Delphine Lissa, Vinodh Rajapakse, Suresh kumar, Yang Zhang, Elmeskini Rajaa, Donna Butcher, Linda Scuito, Jingjing Gong, Brett Schroder, Andrew Warner, Samantha Nichols, Jordan Kimberly, Alejandro Schaffer, Mohit kumar Jolly, Stephen Hewitt, Anish Thomas
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5828.
https://doi.org/10.1158/1538-7445.AM2023-5828
Published: 04 April 2023
View articletitled, Abstract 5828: Distinct immunosuppressive tumor microenvironment modulates small cell lung carcinoma neuroendocrine phenotypic plasticity and heterogeneity
Journal Articles

Abstract P2-19-02: Androgen mediated signaling induces epithelial to mesenchymal transition phenotype in MDA-MB-453 breast cancer cells and human breast tumors

Savitha Rajarajan, Snijesh VP, Madhumathy G Nair, Apoorva D, Chandrakala M, Vidya P Nimbalkar, Maalavika Pillai, Mohit Kumar Jolly, Jyothi S Prabhu
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-19-02.
https://doi.org/10.1158/1538-7445.SABCS22-P2-19-02
Published: 01 March 2023
View articletitled, Abstract P2-19-02: Androgen mediated signaling induces epithelial to mesenchymal transition phenotype in MDA-MB-453 breast cancer cells and human breast tumors
Journal Articles

Abstract P5-04-04: Identification of AR driven tumors within TNBC using a novel gene signature

Savitha Rajarajan, Snijesh V.P, Maalavika Pillai, Mohit Kumar Jolly, Jyothi S Prabhu
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-04-04.
https://doi.org/10.1158/1538-7445.SABCS21-P5-04-04
Published: 15 February 2022
View articletitled, Abstract P5-04-04: Identification of AR driven tumors within TNBC using a novel gene signature
Journal Articles

Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis

Ana Rita Lourenco, Yi Ban, Michael J. Crowley, Sharrell B. Lee, Divya Ramchandani, Wei Du, Olivier Elemento, Jason T. George, Mohit Kumar Jolly, Herbert Levine, Jianting Sheng, Stephen T. Wong, Nasser K. Altorki, Dingcheng Gao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (2): 163–169.
https://doi.org/10.1158/0008-5472.CAN-19-1427
Published: 15 January 2020
View articletitled, Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis
Open the PDF for Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types

Federico Bocci, Mohit Kumar Jolly, José Nelson Onuchic
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5527–5535.
https://doi.org/10.1158/0008-5472.CAN-19-1726
Published: 01 November 2019
View articletitled, A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
Open the PDF for A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types in another window
Includes: Supplementary data
Journal Articles

Abstract 2783: OMICS analysis of breast cancer PDX tumors to determine CTC-cluster-specific signature in predicting breast cancer metastasis

Hariprasad Thangavel, Carmine De Angelis, Suhas Vasaikar, Raksha Bhat, Mohit Kumar Jolly, Lacey Elizabeth Dobrolecki, Jason T. George, Mario Giuliano, Michael Lewis, Herbert Levine, Bing Zhang, Rachel Schiff, Meghana V. Trivedi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2783.
https://doi.org/10.1158/1538-7445.AM2019-2783
Published: 01 July 2019
View articletitled, Abstract 2783: OMICS analysis of breast cancer PDX tumors to determine CTC-cluster-specific signature in predicting breast cancer metastasis
Journal Articles

Spleen Tyrosine Kinase–Mediated Autophagy Is Required for Epithelial–Mesenchymal Plasticity and Metastasis in Breast Cancer

Aparna Shinde, Shana D. Hardy, Dongwook Kim, Saeed Salehin Akhand, Mohit Kumar Jolly, Wen-Hung Wang, Joshua C. Anderson, Ryan B. Khodadadi, Wells S. Brown, Jason T. George, Sheng Liu, Jun Wan, Herbert Levine, Christopher D. Willey, Casey J. Krusemark, Robert L. Geahlen, Michael K. Wendt
Journal: Cancer Research
Cancer Res (2019) 79 (8): 1831–1843.
https://doi.org/10.1158/0008-5472.CAN-18-2636
Published: 15 April 2019
View articletitled, Spleen Tyrosine Kinase–Mediated Autophagy Is Required for Epithelial–Mesenchymal Plasticity and Metastasis in Breast Cancer
Open the PDF for Spleen Tyrosine Kinase–Mediated Autophagy Is Required for Epithelial–Mesenchymal Plasticity and Metastasis in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4999: Identifying intercellular phenotypic stability factors for a hybrid epithelial-mesenchymal phenotype

Mohit Kumar Jolly, Federico Bocci, Satyendra C. Tripathi, Mitzi Aguilar, Samir M. Hanash, Herbert Levine, Jose N. Onuchic
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4999.
https://doi.org/10.1158/1538-7445.AM2018-4999
Published: 01 July 2018
View articletitled, Abstract 4999: Identifying intercellular phenotypic stability factors for a hybrid epithelial-mesenchymal phenotype
Journal Articles

XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype

Myron K. Evans, Michael C. Brown, Joseph Geradts, Xuhui Bao, Timothy J. Robinson, Mohit Kumar Jolly, Peter B. Vermeulen, Gregory M. Palmer, Matthias Gromeier, Herbert Levine, Michael A. Morse, Steven J. Van Laere, Gayathri R. Devi
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1726–1738.
https://doi.org/10.1158/0008-5472.CAN-17-1667
Published: 01 April 2018
View articletitled, XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype
Open the PDF for XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype in another window
Includes: Supplementary data
Journal Articles

Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric

Jason T. George, Mohit Kumar Jolly, Shengnan Xu, Jason A. Somarelli, Herbert Levine
Journal: Cancer Research
Cancer Res (2017) 77 (22): 6415–6428.
https://doi.org/10.1158/0008-5472.CAN-16-3521
Published: 14 November 2017
View articletitled, Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric
Open the PDF for Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric in another window
Includes: Supplementary data
Journal Articles

Abstract 3053: Stability and stemness of the hybrid epithelial-mesenchymal phenotype

Mohit Kumar Jolly, Dongya Jia, Satyendra C. Tripathi, Steve Mooney, Muge Celiktas, Samir M. Hanash, Sendurai A. Mani, Kenneth J. Pienta, Eshel Ben-Jacob, Herbert Levine
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3053.
https://doi.org/10.1158/1538-7445.AM2017-3053
Published: 01 July 2017
View articletitled, Abstract 3053: Stability and stemness of the hybrid epithelial-mesenchymal phenotype
Journal Articles

Abstract B2-24: OVOL: A brake on EMT, driver of MET and expander of the hybrid E/M phenotype

Dongya Jia, Mohit Kumar Jolly, Marcelo Boareto, Princy Parsana, Steven Mooney, Kenneth J. Pienta, Herbert Levine, Eshel Ben-Jacob
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B2-24.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-24
Published: 15 November 2015
View articletitled, Abstract B2-24: OVOL: A brake on EMT, driver of MET and expander of the hybrid E/M phenotype
Journal Articles

Abstract B2-49: Coupled cellular decision-making of EMT and stemness: A bottom-up regulatory model

Mohit Kumar Jolly, Bin Huang, Mingyang Lu, Sendurai A Mani, Herbert Levine, Eshel Ben-Jacob
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B2-49.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-49
Published: 15 November 2015
View articletitled, Abstract B2-49: Coupled cellular decision-making of EMT and stemness: A bottom-up regulatory model
Journal Articles

Abstract 1133: Partial EMT, hybrid epithelial-mesenchymal phenotype and epithelial plasticity: role of (miR-200/ZEB) loop

Mohit Kumar Jolly, Mingyang Lu, Herbert Levine, Jose N. Onuchic, Eshel Ben-Jacob
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1133.
https://doi.org/10.1158/1538-7445.AM2014-1133
Published: 01 October 2014
View articletitled, Abstract 1133: Partial EMT, hybrid epithelial-mesenchymal phenotype and epithelial plasticity: role of (miR-200/ZEB) loop
Journal Articles

Toward Decoding the Principles of Cancer Metastasis Circuits

Mingyang Lu, Mohit Kumar Jolly, Jose' Onuchic, Eshel Ben-Jacob
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4574–4587.
https://doi.org/10.1158/0008-5472.CAN-13-3367
Published: 01 September 2014
View articletitled, Toward Decoding the Principles of Cancer Metastasis Circuits
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