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Mirentxu Santos
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Journal Articles

In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer

Mirentxu Santos, Mónica Martínez-Fernández, Marta Dueñas, Ramón García-Escudero, Begoña Alfaya, Felipe Villacampa, Cristina Saiz-Ladera, Clotilde Costa, Marta Oteo, José Duarte, Victor Martínez, Ma José Gómez-Rodriguez, Ma Luisa Martín, Manoli Fernández, Patrick Viatour, Miguel A. Morcillo, Julien Sage, Daniel Castellano, Jose L. Rodriguez-Peralto, Federico de la Rosa, Jesús M Paramio
Journal: Cancer Research
Cancer Res (2014) 74 (22): 6565–6577.
https://doi.org/10.1158/0008-5472.CAN-14-1218
Published: 13 November 2014
View article titled, <em>In Vivo</em> Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
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Includes: Supplementary data
Journal Articles

Deficiency in p53 but not Retinoblastoma Induces the Transformation of Mesenchymal Stem Cells In vitro and Initiates Leiomyosarcoma In vivo

Ruth Rubio, Javier García-Castro, Iván Gutiérrez-Aranda, Jesús Paramio, Mirentxu Santos, Purificación Catalina, Paola E. Leone, Pablo Menendez, René Rodríguez
Journal: Cancer Research
Cancer Res (2010) 70 (10): 4185–4194.
https://doi.org/10.1158/0008-5472.CAN-09-4640
Published: 12 May 2010
View article titled, Deficiency in p53 but not Retinoblastoma Induces the Transformation of Mesenchymal Stem Cells <em>In vitro</em> and Initiates Leiomyosarcoma <em>In vivo</em>
Open the PDF for Deficiency in p53 but not Retinoblastoma Induces the Transformation of Mesenchymal Stem Cells <em>In vitro</em> and Initiates Leiomyosarcoma <em>In vivo</em> in another window
Includes: Supplementary data
Journal Articles

Akt Activation Synergizes with Trp53 Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma

Marta Moral, Carmen Segrelles, M. Fernanda Lara, Ana Belén Martínez-Cruz, Corina Lorz, Mirentxu Santos, Ramón García-Escudero, Jerry Lu, Kaoru Kiguchi, Agueda Buitrago, Clotilde Costa, Cristina Saiz, Jose L. Rodriguez-Peralto, Francisco J. Martinez-Tello, Maria Rodriguez-Pinilla, Montserrat Sanchez-Cespedes, Marina Garín, Teresa Grande, Ana Bravo, John DiGiovanni, Jesús M. Paramio
Journal: Cancer Research
Cancer Res (2009) 69 (3): 1099–1108.
https://doi.org/10.1158/0008-5472.CAN-08-3240
Published: 29 January 2009
View article titled, Akt Activation Synergizes with <em>Trp53</em> Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma
Open the PDF for Akt Activation Synergizes with <em>Trp53</em> Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

Ana Belén Martínez-Cruz, Mirentxu Santos, M. Fernanda Lara, Carmen Segrelles, Sergio Ruiz, Marta Moral, Corina Lorz, Ramón García-Escudero, Jesús M. Paramio
Journal: Cancer Research
Cancer Res (2008) 68 (3): 683–692.
https://doi.org/10.1158/0008-5472.CAN-07-3049
Published: 01 February 2008
View article titled, Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of <em>Retinoblastoma</em> and <em>Trp53</em> Tumor Suppressors
Open the PDF for Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of <em>Retinoblastoma</em> and <em>Trp53</em> Tumor Suppressors in another window
Includes: Supplementary data
Journal Articles

Deregulated Activity of Akt in Epithelial Basal Cells Induces Spontaneous Tumors and Heightened Sensitivity to Skin Carcinogenesis

Carmen Segrelles, Jerry Lu, Brian Hammann, Mirentxu Santos, Marta Moral, José Luis Cascallana, M. Fernanda Lara, Okkyung Rho, Steve Carbajal, Jeanine Traag, Linda Beltrán, Ana Belén Martínez-Cruz, Ramón García-Escudero, Corina Lorz, Sergio Ruiz, Ana Bravo, Jesús M. Paramio, John DiGiovanni
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10879–10888.
https://doi.org/10.1158/0008-5472.CAN-07-2564
Published: 15 November 2007
View article titled, Deregulated Activity of Akt in Epithelial Basal Cells Induces Spontaneous Tumors and Heightened Sensitivity to Skin Carcinogenesis
Open the PDF for Deregulated Activity of Akt in Epithelial Basal Cells Induces Spontaneous Tumors and Heightened Sensitivity to Skin Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

Unexpected Roles for pRb in Mouse Skin Carcinogenesis

Sergio Ruiz, Mirentxu Santos, M. Fernanda Lara, Carmen Segrelles, Claudio Ballestín, Jesús M. Paramio
Journal: Cancer Research
Cancer Res (2005) 65 (21): 9678–9686.
https://doi.org/10.1158/0008-5472.CAN-05-1853
Published: 01 November 2005
View article titled, Unexpected Roles for pRb in Mouse Skin Carcinogenesis
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