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Journal Articles

Abstract 1791: Epigenetically upregulating TROP2 enhances therapeutic efficacy of TROP2 ADC sacitizumab govitecan

Ming Zhao, Timothy P. DiPeri, Gabriela Raso, Yasmeen Q. Rizvi, Xiaofeng Zheng, Kurt Evans, Argun Akcakanat, Fei Yang, Debu Tripathy, Ecaterina Ileana Dumbrava, Senthil Damodaran, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1791.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1791
Published: 15 June 2022
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Journal Articles

Abstract 2618: Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in cholangiocarcinoma with FGFR fusions/rearrangements

TImothy P. DiPeri, Ming Zhao, Tyler Moss, Michael Kahle, Payal Rauli, Sunyoung S. Lee, Abdel Halim, Hiroshi Hirai, Volker Wacheck, Karim Benhadji, Jordi Rodon, Milind Javle, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2618.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2618
Published: 15 June 2022
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Journal Articles

Abstract P5-08-12: Efficacy of futibatinib, an irreversible fibroblast growth factor receptor (FGFR) inhibitor, in breast cancer models with FGFR alterations

Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W. Evans, Erkan Yuca, Stephen Scott, Bryce P. Kirby, Xiaofeng Zheng, Senthil Damodaran, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-08-12.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-08-12
Published: 15 February 2022
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Journal Articles

Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer

Kurt W. Evans, Erkan Yuca, Stephen S. Scott, Ming Zhao, Natalia Paez Arango, Christian X. Cruz Pico, Turcin Saridogan, Maryam Shariati, Caleb A. Class, Christopher A. Bristow, Christopher P. Vellano, Xiaofeng Zheng, Ana Maria Gonzalez-Angulo, Xiaoping Su, Coya Tapia, Ken Chen, Argun Akcakanat, Bora Lim, Debu Tripathy, Timothy A. Yap, Maria Emilia Di Francesco, Giulio F. Draetta, Philip Jones, Timothy P. Heffernan, Joseph R. Marszalek, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5572–5581.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-3242
Published: 01 November 2021
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Includes: Supplementary data
Journal Articles

Abstract PS18-37: Loss of Trop2 protein in metaplastic carcinoma of breast by IHC

Fei Yang, Yasmeen Rizvi, Erkan Yuca, Ming Zhao, Kurt Evans, Xiaofeng Zheng, Aysegul Sahin, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-37.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS18-37
Published: 15 February 2021
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Journal Articles

Abstract 676A: Overcoming PARP inhibitor resistance with molecularly guided rational combinations in triple-negative breast cancer patient-derived xenograft models

Christian X. Cruz Pico, Kurt W. Evans, Ken Chen, Xiaofeng Zheng, Argun Akcakanat, Ming Zhao, Coya Tapia, Stephen M. Scott, Erkan Yuca, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 676A.
DOI: https://doi.org/10.1158/1538-7445.AM2020-676A
Published: 15 August 2020
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Journal Articles

Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts

Jessica Giordano, Xing Yi Woo, Anuj Srivastava, Zi-Ming Zhao, Michael W. Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Francesco Galimi, Andrea Bertotti, Adam Lafferty, Alice C. O'Farrell, Elodie Modave, Diether Lambrechts, Petra ter Brugge, Violeta Serra, Elisabetta Marangoni, Rania El Botty, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A. Dean, Brandi Davis-Dusenbery, Yvonne A. Evrard, James H. Doroshow, Alana L. Welm, Bryan E. Welm, Michael T. Lewis, Bingliang Fang, Jack Roth, Funda Meric-Bernstam, Meenhard Herlyn, Michael Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Jeffrey A. Moscow, Carol J. Bult, Claudio Isella, Livio Trusolino, Annette T. Byrne, Jos Jonkers, Jeffrey H. Chuang, Enzo Medico, EurOPDX consortium & PDXNET consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1118.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1118
Published: 15 August 2020
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Journal Articles

Abstract 1673: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W. Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A. Dean, Brandi Davis-Dusenbery, Yvonne A. Evrard, James H. Doroshow, Alana L. Welm, Bryan Welm, Michael T. Lewis, Bingliang Fang, Jack A. Roth, Funda Meric-Bernstam, Meenhard Herlyn, Michael Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Claudio Isella, Jeffrey A. Moscow, Livio Trusolino, Annette Byrne, Jos Jonkers, Carol J. Bult, Enzo Medico, Jeffrey H. Chuang, PDXNET consortium & EurOPDX consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1673.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1673
Published: 15 August 2020
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Journal Articles

Abstract 5802: Efficacy of PI3Kβ inhibitor AZD8186 in PTEN-deficient triple-negative breast cancer

Nicci Owusu-Brackett, Ming Zhao, Argun Akcakanat, Kurt W. Evans, Erkan Yuca, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5802.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5802
Published: 01 July 2018
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Journal Articles

JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity

Juan Ye, Tian-Sheng Li, Gang Xu, Yi-Ming Zhao, Ning-Ping Zhang, Jia Fan, Jian Wu
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5287–5300.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0229
Published: 01 October 2017
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Includes: Supplementary data
Journal Articles

Abstract 4038: Exploring optimal targeted combination therapies with neratinib for HER2+ breast cancer

Ming Zhao, Stephen Scott, Kurt Evans, Erkan Yuca, Rashmi Murthy, Francesca Avogadri-Connors, Richard Cutler, Alshad S. Lalani, Sarina Piha-Paul, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4038.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4038
Published: 01 July 2017
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Journal Articles

Abstract 859: Epigenetic regulation of epithelial-mesenchymal transition in esophageal squamous cell carcinoma

Chen Chen, Ming Zhao, Xiaojie Huang, Xiang Wang, Wenliang Liu, Mingjiu Chen, Bangliang Yin, Zhi Li, Yunchang Yuan, Qianjin Lu, Fenglei Yu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 859.
DOI: https://doi.org/10.1158/1538-7445.AM2017-859
Published: 01 July 2017
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Journal Articles

Abstract 1908: FGFR inhibitor, AZD4547, impedes the stemness of mammary epithelial cells in the premalignant tissues of MMTV-ErbB2 transgenic mice

Qingxia Zhao, Amanda B. Parris, Erin W. Howard, Ming Zhao, Ying Xing, Zhikun Ma, Xiaohe Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1908.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1908
Published: 01 July 2017
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Journal Articles

Abstract 2223: Rapamycin suppresses ErbB2-overexpressing mammary tumors through selective inhibition of luminal progenitor cells and tumor-initiating cells

Qingxia Zhao, Amanda B. Parris, Erin W. Howard, Ming Zhao, Zhiying Guo, Ying Xing, Zhikun Ma, Xiaohe Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2223.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2223
Published: 01 July 2017
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Journal Articles

Abstract 2874: Inhibition of tumor angiogenesis by Salmonella typhimurium A1-R in the in vivo Gelfoam color-coded imaging assay

Tasuku Kiyuna, Yasunori Tome, Takashi Murakami, Ming Zhao, Fuminori Kanaya, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2874.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2874
Published: 01 July 2017
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Journal Articles

Abstract 89: Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma

Humam Kadara, Murim Choi, Jiexin Zhang, Edwin Parra Cuentas, Jaime Rodriguez Canales, Stephen Gaffney, Zi-Ming Zhao, Carmen Behrens, Junya Fujimoto, Chi-Wan Chow, Neda Kalhor, Cesar Moran, David Rimm, Stephen G. Swisher, Don L. Gibbons, John V. Heymach, Edward Kaftan, Jeffrey Townsend, Thomas J. Lynch, Joseph Schlessinger, J. Jack Lee, Richard Lifton, Ignacio I. Wistuba, Roy S. Herbst
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 89.
DOI: https://doi.org/10.1158/1538-7445.AM2016-89
Published: 15 July 2016
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Journal Articles

Abstract 142: Mutation and immune profiles in early-stage lung squamous cell carcinoma

Murim Choi, Humam Kadara, Jiexin Zhang, Edwin Parra Cuentas, Jaime Rodriguez Canales, Stephen G. Gaffney, Zi-Ming Zhao, Carmen Behrens, Junya Fujimoto, Chi-Wan Chow, Neda Kalhor, Cesar Moran, David Rimm, Stephen Swisher, Don L. Gibbons, John V. Heymach, Edward Kaftan, Jeffrey Townsend, Thomas J. Lynch, Joseph Schlessinger, J. Jack Lee, Richard Lifton, Roy S. Herbst, Ignacio I. Wistuba
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 142.
DOI: https://doi.org/10.1158/1538-7445.AM2016-142
Published: 15 July 2016
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Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Tasuku Kiyuna, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1408.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1408
Published: 15 July 2016
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Abstract 3075: Nuclear export inhibitor selinexor (KPT-330) demonstrates anti-tumor efficacy alone and in combination with chemotherapy in multiple breast cancer models

Natalia Paez Arango, Kurt Evans, Ming Zhao, Erkan Yuca, Stephen Scott, Charissa Kim, Aung Naing, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3075.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3075
Published: 15 July 2016
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Journal Articles

Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, MIchael Bouvet, Itaru Endo, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4220.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4220
Published: 15 July 2016
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