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Journal Articles

Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci

Bin Li, Yimin Cai, Can Chen, Gaoyuan Li, Ming Zhang, Zequn Lu, Fuwei Zhang, Jinyu Huang, Linyun Fan, Caibo Ning, Yanmin Li, Wenzhuo Wang, Hui Geng, Yizhuo Liu, Shuoni Chen, Hanting Li, Shuhui Yang, Heng Zhang, Wen Tian, Zhongchao Zhu, Bin Xu, Heng Li, Haijie Li, Meng Jin, Xiaoyang Wang, Shaokai Zhang, Jiuyang Liu, Chaoqun Huang, Xiaojun Yang, Yongchang Wei, Ying Zhu, Jianbo Tian, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2023)
https://doi.org/10.1158/0008-5472.CAN-23-0251
Published: 05 September 2023
View article titled, Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci
Open the PDF for Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci in another window
Includes: Supplementary data
Journal Articles

Pan-Cancer Analysis of Microbiome Quantitative Trait Loci

Can Chen, Yimin Cai, Yizhuo Liu, Shuoni Chen, Yanmin Li, Fuwei Zhang, Ming Zhang, Zequn Lu, Pingting Ying, Jinyu Huang, Linyun Fan, Xiaomin Cai, Caibo Ning, Wenzhuo Wang, Yuan Jiang, Heng Zhang, Shuhui Yang, Zhihua Wang, Xiaoyang Wang, Shaokai Zhang, Chaoqun Huang, Bin Xu, Zhenming Fu, Qibin Song, Mingjuan Jin, Kun Chen, Hongda Chen, Min Dai, Xiaoping Miao, Xiaojun Yang, Ying Zhu, Jianbo Tian
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3449–3456.
https://doi.org/10.1158/0008-5472.CAN-22-1854
Published: 04 October 2022
View article titled, Pan-Cancer Analysis of Microbiome Quantitative Trait Loci
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Includes: Supplementary data
Journal Articles

Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk

Jianbo Tian, Can Chen, Meilin Rao, Ming Zhang, Zequn Lu, Yimin Cai, Pingting Ying, Bin Li, Haoxue Wang, Lu Wang, Yao Li, Jinyu Huang, Linyun Fan, Xiaomin Cai, Caibo Ning, Yanmin Li, Fuwei Zhang, Wenzhuo Wang, Yuan Jiang, Yizhuo Liu, Min Wang, Heng Li, Chaoqun Huang, Zhiyong Yang, Jiang Chang, Ying Zhu, Xiaojun Yang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2022) 82 (11): 2084–2096.
https://doi.org/10.1158/0008-5472.CAN-21-4367
Published: 06 June 2022
View article titled, Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk
Open the PDF for Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk in another window
Includes: Supplementary data
Journal Articles

Abstract 1515: Hotspot mutations in KRAS and TP53 targeted by TCR-T cells genetically modified with the Sleeping Beauty transposon/transposase system

Ana B. Korngold, Lin-Kin Yong, Ming Zhang, Ugochi Ibekwe, Lenka V. Hurton, Yaoyao Shi, Julissa Simmons, Matthew R. Collinson-Pautz, Eleanor De Groot, Laurence J. Cooper, Drew C. Deniger
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1515.
https://doi.org/10.1158/1538-7445.AM2021-1515
Published: 01 July 2021
View article titled, Abstract 1515: Hotspot mutations in <em>KRAS</em> and <em>TP53</em> targeted by TCR-T cells genetically modified with the <em>Sleeping Beauty</em> transposon/transposase system
Journal Articles

Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2

Jianbo Tian, Jiao Lou, Yimin Cai, Meilin Rao, Zequn Lu, Ying Zhu, Danyi Zou, Xiating Peng, Haoxue Wang, Ming Zhang, Siyuan Niu, Yue Li, Rong Zhong, Jiang Chang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2020) 80 (9): 1804–1818.
https://doi.org/10.1158/0008-5472.CAN-19-2389
Published: 04 May 2020
View article titled, Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both <em>FADS2</em> and <em>AP002754.2</em>
Open the PDF for Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both <em>FADS2</em> and <em>AP002754.2</em> in another window
Includes: Supplementary data
Journal Articles

Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression

Jian-Ping He, Pei-Pei Hou, Qi-Tao Chen, Wei-Jia Wang, Xiao-Yu Sun, Peng-Bo Yang, Ying-Ping Li, Lu-Ming Yao, Xiaotong Li, Xin-Dong Jiang, Kun-Yi Chien, Zhi-Ming Zhang, Qiu-Wan Wu, Allison J. Cowin, Qiao Wu, Hang-Zi Chen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (17): 4853–4864.
https://doi.org/10.1158/0008-5472.CAN-17-3835
Published: 04 September 2018
View article titled, Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
Open the PDF for Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract LB-141: A unified dual-switch CAR vector to target solid cancer with controllable "on" and "off" states

MyLinh Duong, Eva Morschl, Aruna Mahendravada, Matthew Collinson-Pautz, Mary Brandt, Ming Zhang, Aaron Foster, J. Henri Bayle, David Spencer
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-141.
https://doi.org/10.1158/1538-7445.AM2018-LB-141
Published: 01 July 2018
View article titled, Abstract LB-141: A unified dual-switch CAR vector to target solid cancer with controllable "on" and "off" states
Journal Articles

An Essential Role of Maspin in Embryogenesis and Tumor Suppression—Response

Ming Zhang, Mary J.C. Hendrix, Philip A. Pemberton, Wael A. Sakr, Shijie Sheng
Journal: Cancer Research
Cancer Res (2017) 77 (18): 5208–5210.
https://doi.org/10.1158/0008-5472.CAN-17-1254
Published: 14 September 2017
View article titled, An Essential Role of Maspin in Embryogenesis and Tumor Suppression—Response
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Journal Articles

Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors

Ming Zhang, Singh Ratnakar, Shaohua Peng, Mazumdar Tuhina, Shen Li, Pan Tong, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3816.
https://doi.org/10.1158/1538-7445.AM2017-3816
Published: 01 July 2017
View article titled, Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors
Journal Articles

Abstract LB-184: Dual-switchGoCAR-T cells: small molecule-regulated “GO” and “STOP” switches to target solid cancer in vivo

MyLinh T. Duong, Matthew R. Collinson-Pautz, Eva Morschl, Mary E. Brandt, Ming Zhang, Kevin W. Slawin, Aaron E. Foster, J. Henri Bayle, David M. Spencer
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-184.
https://doi.org/10.1158/1538-7445.AM2017-LB-184
Published: 01 July 2017
View article titled, Abstract LB-184: Dual-switchGoCAR-T cells: small molecule-regulated “GO” and “STOP” switches to target solid cancer <em>in vivo</em>
Journal Articles

Abstract 127: The genomic landscapes of inflammatory bowel disease-associated colorectal cancers

Ana I. Robles, Giovanni Traverso, Ming Zhang, Nicholas Roberts, Mohammed A. Khan, Christine Joseph, Gregory Lauwers, Florin Selaru, Maria Popoli, Xiquan Ke, Ralph H. Hruban, Stephen J. Meltzer, Kenneth W. Kinzler, Bert Vogelstein, Curtis C. Harris, Nickolas Papadopoulos
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 127.
https://doi.org/10.1158/1538-7445.AM2016-127
Published: 15 July 2016
View article titled, Abstract 127: The genomic landscapes of inflammatory bowel disease-associated colorectal cancers
Journal Articles

Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma

Faye M. Johnson, Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Pan Tong, Tuhina Mazumdar, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 393.
https://doi.org/10.1158/1538-7445.AM2016-393
Published: 15 July 2016
View article titled, Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma
Journal Articles

Abstract 4757: Identification of biomarkers that predict response of head and neck squamous cell carcinoma to mitotic inhibitors

Ming Zhang, Shaohua Peng, Tuhina Mazumdar, Vaishnavi Sambandam, Li Shen, Pan Tong, Lerong Li, Lauren Byers, Curtis Pickering, Mitchell Frederick, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4757.
https://doi.org/10.1158/1538-7445.AM2016-4757
Published: 15 July 2016
View article titled, Abstract 4757: Identification of biomarkers that predict response of head and neck squamous cell carcinoma to mitotic inhibitors
Journal Articles

Abstract 65: An integrated bioinformatics approach for identifying patient-specific gene networks and novel therapeutic targets in glioblastoma

Vasileios Stathias, Chiara Pastori, Ricardo Komotar, Ming Zhang, Stephan Schürer, Jennifer Clarke, Nagi G. Ayad
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 65.
https://doi.org/10.1158/1538-7445.AM2015-65
Published: 01 August 2015
View article titled, Abstract 65: An integrated bioinformatics approach for identifying patient-specific gene networks and novel therapeutic targets in glioblastoma
Journal Articles

Abstract 4137: Clonal evolution defines the natural history of metastatic pancreatic cancer

Alvin P. Makohon-Moore, Ming Zhang, Johannes G. Reiter, Ivana Bozic, Fay Wong, Yuchen Jiao, Krishnendu Chatterjee, Martin A. Nowak, Nickolas Papadopoulos, Bert Vogelstein, Kenneth W. Kinzler, Christine A. Iacobuzio-Donahue
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4137.
https://doi.org/10.1158/1538-7445.AM2015-4137
Published: 01 August 2015
View article titled, Abstract 4137: Clonal evolution defines the natural history of metastatic pancreatic cancer
Journal Articles

Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

Nicolas Jose Llosa, Michael Cruise, Ada Tam, Elizabeth Wick, Elizabeth Hechenbleikner, Janis Taube, Lee Blosser, Hongni Fan, Hao Wang, Ming Zhang, Brandon Luber, Nickolas Papadopoulos, Kenneth Kinzler, Bert Vogelstein, Cynthia Sears, Robert Anders, Drew Pardoll, Franck Housseau
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 451.
https://doi.org/10.1158/1538-7445.AM2015-451
Published: 01 August 2015
View article titled, Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints
Journal Articles

Abstract 417: Integrative drug sensitivity analysis of PI3K /mTOR pathway inhibitors in Head and Neck Squamous Cell Carcinoma (HNSCC)

Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 417.
https://doi.org/10.1158/1538-7445.AM2015-417
Published: 01 August 2015
View article titled, Abstract 417: Integrative drug sensitivity analysis of PI3K /mTOR pathway inhibitors in Head and Neck Squamous Cell Carcinoma (HNSCC)
Journal Articles

Abstract 2427: The difference of drug sensitivity between HPV-positive and HPV-negative head and neck squamous cell carcinoma cell lines

Ming Zhang, Tuhina Mazumdar, Shaohua Peng, Pan Tong, Vaishnavi Sambandam, Lauren A. Byers, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2427.
https://doi.org/10.1158/1538-7445.AM2015-2427
Published: 01 August 2015
View article titled, Abstract 2427: The difference of drug sensitivity between HPV-positive and HPV-negative head and neck squamous cell carcinoma cell lines
Journal Articles

Abstract 4094: Identification of co-inhibitory receptor expression on T cells from gastric cancer patients

Yunhui Zong, Fuliang Chu, Songbing He, Yu Jing, Sally A Hunsucker, Tina Yang, Ming Zhang, Sisi Ye, Yafen Li, Bin Liu, Jinle Tang, Huimin Meng, Gangli An, Lin Yang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4094.
https://doi.org/10.1158/1538-7445.AM2014-4094
Published: 01 October 2014
View article titled, Abstract 4094: Identification of co-inhibitory receptor expression on T cells from gastric cancer patients
Journal Articles

Abstract LB-114: The long noncoding RNA HOTAIR promotes glioblastoma cell proliferation

Chiara Pastori, Clara Penas, Philipp Kapranov, Georges St.Laurent, Ming Zhang, Nagi Ayad, Claes Wahlestedt
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-114.
https://doi.org/10.1158/1538-7445.AM2014-LB-114
Published: 01 October 2014
View article titled, Abstract LB-114: The long noncoding RNA HOTAIR promotes glioblastoma cell proliferation