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Journal Articles

HIF1α Counteracts TGFβ1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment

Yu-Wei Luo, Yang Fang, Hui-Xian Zeng, Yu-Chen Ji, Meng-Zhi Wu, Hui Li, Jie-Ying Chen, Li-Min Zheng, Jian-Hong Fang, Shi-Mei Zhuang
Journal: Cancer Research
Cancer Res (2025) 85 (1): 69–83.
https://doi.org/10.1158/0008-5472.CAN-24-2324
Published: 02 January 2025
View article titled, HIF1α Counteracts TGFβ1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment
Open the PDF for HIF1α Counteracts TGFβ1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer

Si Min Zheng, Yu Chen Feng, Qin Zhu, Ruo Qi Li, Qian Qian Yan, Liu Teng, Yi Meng Yue, Man Man Han, Kaihong Ye, Sheng Nan Zhang, Teng Fei Qi, Cai Xia Tang, Xiao Hong Zhao, Yuan Yuan Zhang, Liang Xu, Ran Xu, Jun Xing, Mark Baker, Tao Liu, Rick F. Thorne, Lei Jin, Thomas Preiss, Xu Dong Zhang, Shundong Cang, Jin Nan Gao
Journal: Cancer Research
Cancer Res (2024) 84 (9): 1460–1474.
https://doi.org/10.1158/0008-5472.CAN-23-3046
Published: 02 May 2024
View article titled, MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract 4989: Discovery and evaluation of ISM6466A, a novel covalent CDK12 inhibitor for the treatment of cancer

Lihua Min, Hongfu Lu, Yihong Zhang, Jianping Wu, Xin Cai, Min Zheng, Hui Cui, Junwen Qiao, Xiao Ding, Sujata Rao, Feng Ren, Alex Zhavoronkov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4989.
https://doi.org/10.1158/1538-7445.AM2023-4989
Published: 04 April 2023
View article titled, Abstract 4989: Discovery and evaluation of ISM6466A, a novel covalent CDK12 inhibitor for the treatment of cancer
Journal Articles

Abstract OT2-14-01: Pyrotinib after trastuzumab-based adjuvant therapy in high-risk early human epidermal growth factor receptor 2-positive breast cancer: a multicenter phase 2 trial

Feilin Cao, Zhaosheng Ma, Guinv Hu, Xiaotao Zhu, Shuguang Li, Shuzheng Chen, Binglie Chen, Zhanwen Li, Weizhu Wu, Xiaochun Ji, Jingde Shu, Deyou Tao, Xiaoqing Hu, Min Zheng, Ouchen Wang, Qingjing Feng, Jing Hao, Xujun Li
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT2-14-01.
https://doi.org/10.1158/1538-7445.SABCS22-OT2-14-01
Published: 01 March 2023
View article titled, Abstract OT2-14-01: Pyrotinib after trastuzumab-based adjuvant therapy in high-risk early human epidermal growth factor receptor 2-positive breast cancer: a multicenter phase 2 trial
Journal Articles

Abstract 4088: The functional mechanism of Clk2 supporting the development of chemoresistance in non-BRCA1 deficient ovarian cancer

Shuting Huang, Yinan Jiang, Min Zheng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4088.
https://doi.org/10.1158/1538-7445.AM2020-4088
Published: 15 August 2020
View article titled, Abstract 4088: The functional mechanism of Clk2 supporting the development of chemoresistance in non-BRCA1 deficient ovarian cancer
Journal Articles

Abstract 4316: Frequent microsatellite instability in Chinese solid tumor patients

Huilin Wang, Jiang Zhu, Guanbiao Liang, Yongyong Wang, Jianji Guo, Min Zheng, Qin Fu, Weiwei Shi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4316.
https://doi.org/10.1158/1538-7445.AM2020-4316
Published: 15 August 2020
View article titled, Abstract 4316: Frequent microsatellite instability in Chinese solid tumor patients
Journal Articles

Abstract 3986: Regulation mechanism and clinical significance of KPNA2 promotes MDSCs infiltrating in epithelial ovarian cancer

Shuting Huang, Min Zheng, Yuanzhong Wu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3986.
https://doi.org/10.1158/1538-7445.AM2017-3986
Published: 01 July 2017
View article titled, Abstract 3986: Regulation mechanism and clinical significance of KPNA2 promotes MDSCs infiltrating in epithelial ovarian cancer
Journal Articles

Abstract 3546: DNA-damaging reagent -0404 effectively inhibits hepatocellular carcinoma through p53-dependent autophagy

Min Zheng, Bingjue Ye, Guohua Lou, Caixia Xia, Weiyang Zheng, Yanning Yanning, Xiao Xu, Yongchao Zhao, Long Mao, Wanghong Xu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3546.
https://doi.org/10.1158/1538-7445.AM2016-3546
Published: 15 July 2016
View article titled, Abstract 3546: DNA-damaging reagent -0404 effectively inhibits hepatocellular carcinoma through p53-dependent autophagy
Journal Articles

Abstract 1645: DNA-damaging compound 0404 effectively inhibits hepatocellular carcinoma by upregulation of miR-34a and miR-200c expression

Caixia Xia, Yanning Liu, Guohua Lou, Xiao Xu, Long Mao, Min Zheng
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1645.
https://doi.org/10.1158/1538-7445.AM2015-1645
Published: 01 August 2015
View article titled, Abstract 1645: DNA-damaging compound 0404 effectively inhibits hepatocellular carcinoma by upregulation of miR-34a and miR-200c expression
Journal Articles

Abstract 4215: SPAG5 upregulation predicts poor prognosis of cervical cancer patients and alters the sensitivity of Taxol treatment via mTOR signaling pathway

Lin-Jing Yuan, Lan Zhang, Yun Zhou, Min Zheng
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4215.
https://doi.org/10.1158/1538-7445.AM2014-4215
Published: 01 October 2014
View article titled, Abstract 4215: SPAG5 upregulation predicts poor prognosis of cervical cancer patients and alters the sensitivity of Taxol treatment via mTOR signaling pathway
Journal Articles

Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition

Zhen Wang, Min Zheng, Zhichuan Li, Ruiguo Li, Lijun Jia, Xiufang Xiong, Noel Southall, Shaomeng Wang, Menghang Xia, Christopher P. Austin, Wei Zheng, Zijian Xie, Yi Sun
Journal: Cancer Research
Cancer Res (2009) 69 (16): 6556–6564.
https://doi.org/10.1158/0008-5472.CAN-09-0891
Published: 12 August 2009
View article titled, Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
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Includes: Supplementary data
Journal Articles

Abstract #LB-10: Neurofibromin directly interacts with the N-terminal domain of Focal Adhesion Kinase

Frederick Kweh, Min Zheng, Elena Kurenova, Margaret Wallace, Vita Golubovskaya, William Cance
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-10.
Published: 01 May 2009
View article titled, Abstract #LB-10: Neurofibromin directly interacts with the N-terminal domain of Focal Adhesion Kinase
Journal Articles

Abstract #1926: A small-molecule inhibitor, targeting FAK and Mdm-2 interaction, blocks breast and colon tumorigenesis in vivo.

Nadia Palma, Vita Golubovskaya, Min Zheng, Andrew Magis, David Ostrov, William Cance
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1926.
Published: 01 May 2009
View article titled, Abstract #1926: A small-molecule inhibitor, targeting FAK and Mdm-2 interaction, blocks breast and colon tumorigenesis <em>in vivo.</em>
Journal Articles

Abstract #3508: Role of focal adhesion kinase (FAK), dominant-negative FAK, FAK-CD and FAKsiRNA in human MCF-7 breast cancer cell tumorigenesis

Vita Golubovskaya, Min Zheng, Jian-Liang Li, William Cance
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3508.
Published: 01 May 2009
View article titled, Abstract #3508: Role of focal adhesion kinase (FAK), dominant-negative FAK, FAK-CD and FAKsiRNA in human MCF-7 breast cancer cell tumorigenesis
Journal Articles

Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2

Min Zheng, Susan E. Morgan-Lappe, Jie Yang, Katrina M. Bockbrader, Deepika Pamarthy, Dafydd Thomas, Stephen W. Fesik, Yi Sun
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7570–7578.
https://doi.org/10.1158/0008-5472.CAN-08-0632
Published: 14 September 2008
View article titled, Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2
Open the PDF for Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2 in another window