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Journal Articles

Abstract 4513: The role of HPK1 in the regulation of T cell function and anti-tumor immune activity

Yaoyu Chen, Jonathan Rios-Doria, Michelle Pusey, Kerri Lasky, Min Ye, Pramod Thekkat, Karen Gallagher, Kristine Stump, Patricia Conlen, Christine Gardiner, Hui Wang, Alexander Sokolsky, Mark Rupar, Luping Lin, Elham Behshad, Maryanne Covington, Holly Koblish, Oleg Vechorkin, Wenqing Yao, Sunkyu Kim, Yingnan Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4513.
https://doi.org/10.1158/1538-7445.AM2020-4513
Published: 15 August 2020
View article titled, Abstract 4513: The role of HPK1 in the regulation of T cell function and anti-tumor immune activity
Journal Articles

Abstract 1888: The FAD-directed LSD1 specific inhibitor, INCB059872, is a promising epigenetic agent for AML therapy by inducing differentiation of leukemic stem/progenitor cells

Antony Chadderton, Min Ye, Melody Diamond, Valerie Roman, Michael Weber, Chunhong He, Liangxing Wu, Swamy Yeleswaram, Alan Roberts, Wenqing Yao, Gregory Hollis, Reid Huber, Peggy Scherle, Bruce Ruggeri, Sang Hyun Lee
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1888.
https://doi.org/10.1158/1538-7445.AM2018-1888
Published: 01 July 2018
View article titled, Abstract 1888: The FAD-directed LSD1 specific inhibitor, INCB059872, is a promising epigenetic agent for AML therapy by inducing differentiation of leukemic stem/progenitor cells
Journal Articles

Abstract 1893: The evaluation of INCB059872, an FAD-directed inhibitor of LSD1, in preclinical models of T-ALL

Melody Diamond, Yvonne Lo, Antony Chadderton, Min Ye, Valerie Roman, Michael Weber, Chunhong He, Liangxing Wu, Swamy Yeleswaram, Alan Roberts, Wenqing Yao, Gregory Hollis, Reid Huber, Peggy Scherle, Bruce Ruggeri, Sang Hyun Lee
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1893.
https://doi.org/10.1158/1538-7445.AM2018-1893
Published: 01 July 2018
View article titled, Abstract 1893: The evaluation of INCB059872, an FAD-directed inhibitor of LSD1, in preclinical models of T-ALL
Journal Articles

Abstract 3759: Characterization of INCB081776, a potent and selective dual AXL/MER kinase inhibitor

Margaret Favata, Kerri Lasky, Yvonne Lo, Patricia Feldman, Jun Li, Yaoyu Chen, Christina Stevens, Min Ye, Hui Wang, Ke Liu, Richard Wynn, Yanlong Li, Jennifer Harris, Robert Landman, Yu Li, Xiaozhao Wang, Chunhong He, Yun-Long Li, Chu-Biao Xue, Wenqing Yao, Jonathan Rios-Doria, Zhenhai Gao, Maryanne Covington, Xuesong M. Liu, Holly Koblish, Peggy Scherle
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3759.
https://doi.org/10.1158/1538-7445.AM2018-3759
Published: 01 July 2018
View article titled, Abstract 3759: Characterization of INCB081776, a potent and selective dual AXL/MER kinase inhibitor
Journal Articles

Abstract 271: Diterpenoid pseudolaric acid B induces M-phase arrest and apoptosis primarily through JNK stress signaling in LNCaP prostate cancer cells

Kartick C. Pramanik, Nehal Gupta, Min Ye, Junxuan Lu, Cheng Jiang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 271.
https://doi.org/10.1158/1538-7445.AM2018-271
Published: 01 July 2018
View article titled, Abstract 271: Diterpenoid pseudolaric acid B induces M-phase arrest and apoptosis primarily through JNK stress signaling in LNCaP prostate cancer cells
Journal Articles

Abstract 1162: The evaluation of INCB059872, an FAD-directed covalent inhibitor of LSD1, in preclinical models of Ewing sarcoma

Valerie Dostalik Roman, Min Ye, Huiqing Liu, Melody Diamond, Antony Chadderton, Yvonne Lo, Xuesong M. Liu, Jin Lu, Chunhong He, Liangxing Wu, Timothy Burn, Richard Wynn, Wenqing Yao, Gregory Hollis, Gregory Hollis, Peggy Scherle, Bruce Ruggeri, Sang Hyun Lee
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1162.
https://doi.org/10.1158/1538-7445.AM2017-1162
Published: 01 July 2017
View article titled, Abstract 1162: The evaluation of INCB059872, an FAD-directed covalent inhibitor of LSD1, in preclinical models of Ewing sarcoma
Journal Articles

Abstract 4712: Discovery of INCB059872, a novel FAD-directed LSD1 inhibitor that is effective in preclinical models of human and murine AML

Sang Hyun Lee, Matthew Stubbs, Xuesong Mike Liu, Melody Diamond, Valerie Dostalik, Min Ye, Yvonne Lo, Margaret Favata, Gengjie Yang, Karen Gallagher, Lynn Leffet, Chunhong He, Liangxing Wu, Alexander Margulis, Maryanne Covington, Richard Wynn, Wenqing Yao, Gregory Hollis, Reid Huber, Bruce Ruggeri, Peggy Scherle
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4712.
https://doi.org/10.1158/1538-7445.AM2016-4712
Published: 15 July 2016
View article titled, Abstract 4712: Discovery of INCB059872, a novel FAD-directed LSD1 inhibitor that is effective in preclinical models of human and murine AML
Journal Articles

Abstract 4696: The LSD1 inhibitor INCB059872 is synergistic with ATRA in models of non-APL acute myelogenous leukemia

Min Ye, Mike Liu, Jin Lu, Yvonne Lo, Margaret Favata, Gengjie Yang, Melody Diamond, Valerie Dostalik, Paul Waeltz, Melissa Ann Fischer, Chunhong He, Liangxing Wu, Xiaochuan Shan, Hong Chang, Maryanne Covington, Yanlong Li, Tim Burn, Richard Wynn, Wenqing Yao, Gregory Hollis, Reid Huber, Peggy Scherle, Michael Savona, Martin Carroll, Bruce Ruggeri, Sang Hyun Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4696.
https://doi.org/10.1158/1538-7445.AM2016-4696
Published: 15 July 2016
View article titled, Abstract 4696: The LSD1 inhibitor INCB059872 is synergistic with ATRA in models of non-APL acute myelogenous leukemia
Journal Articles

Abstract 4702: Combination of BET inhibitor INCB054329 and LSD1 inhibitor INCB059872 is synergistic for the treatment of AML in vitro and in vivo

Xuesong Liu, Matthew Stubbs, Min Ye, Roberts Collins, Margaret Favata, Gengjie Yang, Melody Diamond, Valerie Dostalik, Yvonne Lo, Chunhong He, Liangxing Wu, Andrew Combs, Wenqing Yao, Gregory Hollis, Reid Huber, Peggy Scherle, Bruce Ruggeri, Phillip Liu, Sang Hyun Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4702.
https://doi.org/10.1158/1538-7445.AM2016-4702
Published: 15 July 2016
View article titled, Abstract 4702: Combination of BET inhibitor INCB054329 and LSD1 inhibitor INCB059872 is synergistic for the treatment of AML <em>in vitro</em> and <em>in vivo</em>
Journal Articles

Abstract LB-46: C/EBPα acts as tumor suppressor in lung cancer by inhibiting the proto-oncogene Bmi-1.

Elena Levantini, Daniela S. Basseres, Wen Cai Zhang, Robert S. Welner, Meritxell Alberich-Jorda', Kol Jia Yong, Bhavin M. Thakkar, Junyan Zhang, Chiara Battelli, Christopher J. Hetherington, Min Ye, Karen O'Brien, Maria Cristina Magli, Marie Loh, Min En Nga, Yin Huei Pang, Alain C. Borczuk, Lyuba Varticovski, Olivier Kocher, Pu Zhang, Ross A. Soo, Bing Lim, Balazs Halmos, Daniel G. Tenen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-46.
https://doi.org/10.1158/1538-7445.AM2013-LB-46
Published: 15 April 2013
View article titled, Abstract LB-46: C/EBPα acts as tumor suppressor in lung cancer by inhibiting the proto-oncogene Bmi-1.
Journal Articles

Abstract 2317: Identification of Sox4 as a key oncogene in leukemias with mutated or silenced C/EBPα.

Hong Zhang, Min Ye, Meritxell Alberich-Jordà, Giovanni Amabile, Henry Yang, Rob Welner, Philipp Staber, Véronique Lefebvre, Peter J.M. Valk, Ruud Delwel, Constanze Bonifer, Daniel G. Tenen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2317.
https://doi.org/10.1158/1538-7445.AM2013-2317
Published: 15 April 2013
View article titled, Abstract 2317: Identification of Sox4 as a key oncogene in leukemias with mutated or silenced C/EBPα.
Journal Articles

Abstract 4514: Proteasome inhibition causes regression of leukemia in part through regulation of forkhead tumor suppressors

Amrik Singh, Min Ye, Keli Song, Octavian Bucur, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4514.
https://doi.org/10.1158/1538-7445.AM10-4514
Published: 15 April 2010
View article titled, Abstract 4514: Proteasome inhibition causes regression of leukemia in part through regulation of forkhead tumor suppressors
Journal Articles

A Double Hit to Kill Tumor and Endothelial Cells by TRAIL and Antiangiogenic 3TSR

Bin Ren, Keli Song, Sareh Parangi, Taiguang Jin, Min Ye, Robin Humphreys, Mark Duquette, Xuefeng Zhang, Nordine Benhaga, Jack Lawler, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2009) 69 (9): 3856–3865.
https://doi.org/10.1158/0008-5472.CAN-08-2940
Published: 30 April 2009
View article titled, A Double Hit to Kill Tumor and Endothelial Cells by TRAIL and Antiangiogenic 3TSR
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Includes: Supplementary data
Journal Articles

A novel herb-drug interaction: Irinotecan can significantly change the pharmacokinetics and pharmacodynamics of PHY906, a Chinese medicine formulation for cancer therapy

Min Ye, Zaoli Jiang, Wing Lam, Ginger Dutschman, Scott Bussom, Pei-chun Chen, Shwu-Huey Liu, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 635.
Published: 01 May 2008
View article titled, A novel herb-drug interaction: Irinotecan can significantly change the pharmacokinetics and pharmacodynamics of PHY906, a Chinese medicine formulation for cancer therapy
Journal Articles

PHY906 in hepatocellular carcinoma

Shwu-Huey Liu, Zaoli Jiang, Angeline Foo, Wing Lam, Min Ye, Yashang Lee, Duncan Liang, Susan Grill, Yun Yen, Michal Rose, Samuel So, Wasif Saif, Edward Chu, Robert Tilton, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1841.
Published: 01 May 2007
View article titled, PHY906 in hepatocellular carcinoma