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Journal Articles

Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou, Yaqin Zhang, Changmin Peng, Yunxiao Meng, Zhuqing Li, Muhammad Jameel Mughal, Yanjun Gao, Edward Seto, Min Shen, Matthew D. Hall, Junfeng Ma, Cynthia X. Ma, Shunqiang Li, Wenge Zhu

Cancer Res (2025) 85 (9): 1708–1724.

https://doi.org/10.1158/0008-5472.CAN-24-2492

Published: 02 May 2025

View articletitled, Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Includes: Supplementary data

Journal Articles

Abstract 3169: Dependency-agnostic drug discovery: A dual-screening strategy to uncover novel cancer vulnerabilities

Cancer Res (2025) 85 (8_Supplement_1): 3169.

https://doi.org/10.1158/1538-7445.AM2025-3169

Published: 21 April 2025

View articletitled, Abstract 3169: Dependency-agnostic drug discovery: A dual-screening strategy to uncover novel cancer vulnerabilities

Journal Articles

Abstract 3757: Development of potent orally bioavailable inhibitors of nicotinamide N-methyl transferase

Samarjit Patnaik, Janna Heide, Ke Kong, Mark Eckert, Maria Allega, Min Shen, Hongmao Sun, Jonathan Shrimp, Quinlin Hanson, Ken Cheng, Andrew Flint, William J. Moore, Matthew Hall, Gordon M. Stott, Ernst Lengyel

Cancer Res (2025) 85 (8_Supplement_1): 3757.

https://doi.org/10.1158/1538-7445.AM2025-3757

Published: 21 April 2025

View articletitled, Abstract 3757: Development of potent orally bioavailable inhibitors of nicotinamide N-methyl transferase

Journal Articles

Abstract 5488: Identifying novel Ewing sarcoma therapeutics using a high-throughput chromatin accessibility assay

Darian Williams, Andrew McFadden, Austin Hepperla, Min Shen, Tino Sanchez, Gordon Stott, Mark Henderson, Ian Davis, Samantha Pattenden

Cancer Res (2025) 85 (8_Supplement_1): 5488.

https://doi.org/10.1158/1538-7445.AM2025-5488

Published: 21 April 2025

View articletitled, Abstract 5488: Identifying novel Ewing sarcoma therapeutics using a high-throughput chromatin accessibility assay

Journal Articles

Abstract 5505: Combination nitazoxanide and auranofin treatment has synergistic anticancer activity in anaplastic thyroid cancer and act by enhanced activation of multiple cell death pathways

Chandrayee Ghosh, Viswanath Gunda, Jiangnan Hu, Lisa Zhang, Ya-Qin Zhang, Min Shen, Electron Kebebew

Cancer Res (2023) 83 (7_Supplement): 5505.

https://doi.org/10.1158/1538-7445.AM2023-5505

Published: 04 April 2023

View articletitled, Abstract 5505: Combination nitazoxanide and auranofin treatment has synergistic anticancer activity in anaplastic thyroid cancer and act by enhanced activation of multiple cell death pathways

Journal Articles

Abstract 6732: Identifying novel combination therapies for Ewing sarcoma

Maria Ana Isabel C. De Los Santos, Anne-Florence Blandin, Alejandra E. Aguilar, Matthew Hall, Min Shen, Ya-Qin Zhang, Brian D. Crompton

Cancer Res (2023) 83 (7_Supplement): 6732.

https://doi.org/10.1158/1538-7445.AM2023-6732

Published: 04 April 2023

View articletitled, Abstract 6732: Identifying novel combination therapies for Ewing sarcoma

Journal Articles

Abstract 2684: Synergistic efficacy of HSP90 and PI3K inhibitors in adrenocortical carcinoma

Prachi Mishra, Dipranjan Laha, Brieann Sobieski, Min Shen, Ya-Qin Zhang, Matthew Hall, Naris Nilubol

Cancer Res (2023) 83 (7_Supplement): 2684.

https://doi.org/10.1158/1538-7445.AM2023-2684

Published: 04 April 2023

View articletitled, Abstract 2684: Synergistic efficacy of HSP90 and PI3K inhibitors in adrenocortical carcinoma

Journal Articles

Abstract 4069: Development of PSB205, a bifunctional MabPair product that targets PD-1 and CTLA-4

William C. Fanslow, Zhi Liu, Zhonghua Hu, Hua Liu, Min Shen, Yufeng Peng, Cristina Domeier, David Treiber, Ron Schoner, Wei Yan

Cancer Res (2019) 79 (13_Supplement): 4069.

https://doi.org/10.1158/1538-7445.AM2019-4069

Published: 01 July 2019

View articletitled, Abstract 4069: Development of PSB205, a bifunctional MabPair product that targets PD-1 and CTLA-4

Journal Articles

Abstract 5313: Occupational exposure to trichloroethylene and DNA methylation: a cross-sectional study

Jinming Zhang, Luoping Zhang, Roel Vermeulen, Wei Hu, Bryan A. Bassig, Jason Y. Wong, Min Shen, Bu-Tian Ji, Boris Reiss, Mark Purdue, Martyn T. Smith, Qing Lan, Nathaniel Rothman

Cancer Res (2018) 78 (13_Supplement): 5313.

https://doi.org/10.1158/1538-7445.AM2018-5313

Published: 01 July 2018

View articletitled, Abstract 5313: Occupational exposure to trichloroethylene and DNA methylation: a cross-sectional study

Journal Articles

Abstract LB-066: A high-throughput screen of an annotated small molecule library identifies substrates of P-glycoprotein

Tobie D. Lee, Olivia W. Lee, Kyle R. Brimacombe, Min Shen, Lu Chen, Rajarshi Guha, Bethelihem Tebase, Robert W. Robey, Suresh V. Ambudkar, Michael M. Gottesman, Matthew D. Hall

Cancer Res (2018) 78 (13_Supplement): LB-066.

https://doi.org/10.1158/1538-7445.AM2018-LB-066

Published: 01 July 2018

View articletitled, Abstract LB-066: A high-throughput screen of an annotated small molecule library identifies substrates of P-glycoprotein

Journal Articles

Abstract 1943: High-throughput chemical screening identifies Focal Adhesion Kinase and Aurora Kinase B inhibition as a synergistic treatment combination in Ewing sarcoma

Brian Crompton, Sarah Wang, Elizabeth Hwang, Rajarshi Guha, Matthew Boxer, Crystal McKnight, Min Shen, Nicole Melong, Chansey Veinotte, Amy Conway, Jason Berman, Matthew Hall, Mindy Davis, Kimberly Stegmaier

Cancer Res (2017) 77 (13_Supplement): 1943.

https://doi.org/10.1158/1538-7445.AM2017-1943

Published: 01 July 2017

View articletitled, Abstract 1943: High-throughput chemical screening identifies Focal Adhesion Kinase and Aurora Kinase B inhibition as a synergistic treatment combination in Ewing sarcoma

Journal Articles

Abstract 5116: Identification of new treatment options for Merkel cell carcinoma using high throughput chemical screening

Tara Gelb, Daniel Urban, Kenneth Daily, Ying Xiao, Min Shen, Matthew Hall, Isaac Brownell

Cancer Res (2017) 77 (13_Supplement): 5116.

https://doi.org/10.1158/1538-7445.AM2017-5116

Published: 01 July 2017

View articletitled, Abstract 5116: Identification of new treatment options for Merkel cell carcinoma using high throughput chemical screening

Journal Articles

Abstract 4714: Targeting p53 mutant cancers through inhibition of the phosphatidylinositol-5-phosphate 4-kinases

Brooke M. Emerling, Zhiwei Yang, Ryan Loughran, T.Jonathan Yang, Jared Johnson, Rajan Pragani, Mindy Davis, Min Shen, Matthew Boxer, Anton Simeonov, Lewis C. Cantley

Cancer Res (2015) 75 (15_Supplement): 4714.

https://doi.org/10.1158/1538-7445.AM2015-4714

Published: 01 August 2015

View articletitled, Abstract 4714: Targeting p53 mutant cancers through inhibition of the phosphatidylinositol-5-phosphate 4-kinases

Journal Articles

Abstract 840: Occupational exposure to trichloroethylene and LINE-1 methylation

Cancer Res (2015) 75 (15_Supplement): 840.

https://doi.org/10.1158/1538-7445.AM2015-840

Published: 01 August 2015

View articletitled, Abstract 840: Occupational exposure to trichloroethylene and LINE-1 methylation

Journal Articles

Abstract 829: Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde

Cancer Res (2015) 75 (15_Supplement): 829.

https://doi.org/10.1158/1538-7445.AM2015-829

Published: 01 August 2015

View articletitled, Abstract 829: Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde

Journal Articles

Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Warren Fiskus, Nakhle Saba, Min Shen, Mondana Ghias, Jinyun Liu, Soumyasri Das Gupta, Lata Chauhan, Rekha Rao, Sumedha Gunewardena, Kevin Schorno, Christopher P. Austin, Kami Maddocks, John Byrd, Ari Melnick, Peng Huang, Adrian Wiestner, Kapil N. Bhalla

Cancer Res (2014) 74 (9): 2520–2532.

https://doi.org/10.1158/0008-5472.CAN-13-2033

Published: 30 April 2014

View articletitled, Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Includes: Supplementary data

Journal Articles

Abstract 3543: TOP2A is a therapeutic target for adrenocortical carcinoma .

Meenu Jain, Lisa Zhang, Mei He, Ya-Qin Zhang, Naris Nilubol, Min Shen, Electron Kebebew

Cancer Res (2013) 73 (8_Supplement): 3543.

https://doi.org/10.1158/1538-7445.AM2013-3543

Published: 15 April 2013

View articletitled, Abstract 3543: TOP2A is a therapeutic target for adrenocortical carcinoma .

Journal Articles

Abstract 1876: Assessment of exposure to potential lung carcinogens in Xuanwei and Fuyuan, China: Particulate exposure from cooking and heating stoves

Wei Hu, Boris Reiss, Nat Rothman, Kathleen Morales, Jun Xu, Bryan Bassig, Dean Hosgood, Linwei Tian, Xinzhou He, Min Shen, Lawrence Engel, Linlin Zhang, Guoping Wu, Fusheng Wei, Qing Lan, Roel Vermeulen

Cancer Res (2011) 71 (8_Supplement): 1876.

https://doi.org/10.1158/1538-7445.AM2011-1876

Published: 15 April 2011

View articletitled, Abstract 1876: Assessment of exposure to potential lung carcinogens in Xuanwei and Fuyuan, China: Particulate exposure from cooking and heating stoves

Journal Articles

Abstract 4646: Occupational exposure to trichloroethylene and plasma concentrations of IL6, IL10, and TNF alpha

Bryan A. Bassig, Luoping Zhang, Xiaojiang Tang, Roel Vermeulen, Min Shen, Martyn T. Smith, Chuangyi Qiu, Yichen Ge, Zhiying Ji, Boris Reiss, Songwang Liu, Weihong Guo, Mark Purdue, Wei Hu, Laiyu Li, Nathaniel Rothman, Hanlin Huang, Qing Lan

Cancer Res (2011) 71 (8_Supplement): 4646.

https://doi.org/10.1158/1538-7445.AM2011-4646

Published: 15 April 2011

View articletitled, Abstract 4646: Occupational exposure to trichloroethylene and plasma concentrations of IL6, IL10, and TNF alpha

Journal Articles

Abstract 4645: Decreased CD4+ naive and effector memory T cell counts, and CD8+ naïve T cell counts, are associated with trichloroethylene exposure

Cancer Res (2011) 71 (8_Supplement): 4645.

https://doi.org/10.1158/1538-7445.AM2011-4645

Published: 15 April 2011

View articletitled, Abstract 4645: Decreased CD4+ naive and effector memory T cell counts, and CD8+ naïve T cell counts, are associated with trichloroethylene exposure

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Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Abstract 3169: Dependency-agnostic drug discovery: A dual-screening strategy to uncover novel cancer vulnerabilities

Abstract 3757: Development of potent orally bioavailable inhibitors of nicotinamide N-methyl transferase

Abstract 5488: Identifying novel Ewing sarcoma therapeutics using a high-throughput chromatin accessibility assay

Abstract 5505: Combination nitazoxanide and auranofin treatment has synergistic anticancer activity in anaplastic thyroid cancer and act by enhanced activation of multiple cell death pathways

Abstract 6732: Identifying novel combination therapies for Ewing sarcoma

Abstract 2684: Synergistic efficacy of HSP90 and PI3K inhibitors in adrenocortical carcinoma

Abstract 4069: Development of PSB205, a bifunctional MabPair product that targets PD-1 and CTLA-4

Abstract 5313: Occupational exposure to trichloroethylene and DNA methylation: a cross-sectional study

Abstract LB-066: A high-throughput screen of an annotated small molecule library identifies substrates of P-glycoprotein

Abstract 1943: High-throughput chemical screening identifies Focal Adhesion Kinase and Aurora Kinase B inhibition as a synergistic treatment combination in Ewing sarcoma

Abstract 5116: Identification of new treatment options for Merkel cell carcinoma using high throughput chemical screening

Abstract 4714: Targeting p53 mutant cancers through inhibition of the phosphatidylinositol-5-phosphate 4-kinases

Abstract 840: Occupational exposure to trichloroethylene and LINE-1 methylation

Abstract 829: Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde

Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Abstract 3543: TOP2A is a therapeutic target for adrenocortical carcinoma .

Abstract 1876: Assessment of exposure to potential lung carcinogens in Xuanwei and Fuyuan, China: Particulate exposure from cooking and heating stoves

Abstract 4646: Occupational exposure to trichloroethylene and plasma concentrations of IL6, IL10, and TNF alpha

Abstract 4645: Decreased CD4+ naive and effector memory T cell counts, and CD8+ naïve T cell counts, are associated with trichloroethylene exposure

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