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Journal Articles

Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function

Xixi Zhao, Yongkun Wei, Yu-Yi Chu, Yintao Li, Jung-Mao Hsu, Zhou Jiang, Chunxiao Liu, Jennifer L. Hsu, Wei-Chao Chang, Riyao Yang, Li-Chuan Chan, Jingkun Qu, Shuqun Zhang, Haoqiang Ying, Dihua Yu, Mien-Chie Hung

Cancer Res canres.2300.2021.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2300

Published: 06 April 2022

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Includes: Supplementary data

Journal Articles

AMBRA1 Promotes TGFβ Signaling via Nonproteolytic Polyubiquitylation of Smad4

Jinquan Liu, Bo Yuan, Jin Cao, Hongjie Luo, Shuchen Gu, Mengdi Zhang, Ran Ding, Long Zhang, Fangfang Zhou, Mien-Chie Hung, Pinglong Xu, Xia Lin, Jianping Jin, Xin-Hua Feng

Cancer Res (2021) 81 (19): 5007–5020.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-0431

Published: 01 October 2021

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Includes: Supplementary data

Journal Articles

Abstract LB097: MET inhibitor enhances efficacies of gemcitabine and olaparib in pancreatic cancer cells

Meikuang Chen, Yuan Gao, Dihua Yu, Mien-Chie Hung

Cancer Res (2021) 81 (13_Supplement): LB097.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB097

Published: 01 July 2021

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Abstract 3081: Secretory human ribonuclease 1 functions as Eph receptor A4 ligand to promote breast tumor initiation

Ying-Nai Wang, Heng-Huan Lee, Wen-Hao Yang, Gabriel N. Hortobagyi, Dihua Yu, Mien-Chie Hung

Cancer Res (2021) 81 (13_Supplement): 3081.

DOI: https://doi.org/10.1158/1538-7445.AM2021-3081

Published: 01 July 2021

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Abstract 120: Compartmentalized functions of epidermal growth factor receptor (EGFR) in tumorigenesis and malignant phenotypes

Lei Nie, Junwei Hou, Yu-Yi Chu, Ying-Nai Wnag, Li-Chuan Chan, Longfei Huo, Paul Chiao, Shao-Chun Wang, Mien-Chie Hung, Michael Wang

Cancer Res (2021) 81 (13_Supplement): 120.

DOI: https://doi.org/10.1158/1538-7445.AM2021-120

Published: 01 July 2021

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Journal Articles

Abstract 1027: Inhibition of c-MET upregulates PD-L1 related immune escape in lung adenocarcinoma

Xian Sun, Chia-Wei Li, Wei-Jan Wang, Mien-Chie Hung

Cancer Res (2020) 80 (16_Supplement): 1027.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1027

Published: 15 August 2020

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Journal Articles

Abstract 6527: Targeting glycosylated PD-1 induces potent anti-tumor immunity

Yuhan Wang, Linlin Sun, Riyao Yang, Jielin Liu, Yufan Qiu, Jennifer L. Hsu, Jong-ho Cha, Li-Chuan Chan, Jung-Mao Hsu, Heng-Huan Lee, Yun-Ju Lai, Kay-Hooi Khoo, Ezra M Chung, Chia-Wei Li, Yong-Soo Kim, Andrew H Park, Yi Yang, Stephen S. Yoo, Mien-Chie Hung

Cancer Res (2020) 80 (16_Supplement): 6527.

DOI: https://doi.org/10.1158/1538-7445.AM2020-6527

Published: 15 August 2020

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Journal Articles

Abstract 5180: Nuclear receptor tyrosine kinase c-MET restrains efficacy of PARP inhibitor in pancreatic cancer cells

Yuan Gao, Mei-Kuang Chen, Dihua Yu, Mien-Chie Hung

Cancer Res (2020) 80 (16_Supplement): 5180.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5180

Published: 15 August 2020

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Journal Articles

Abstract 5682: Synergism of PARP inhibitor and MET inhibitor in multiple cancer types with intrinsic and acquired PARP inhibitor resistances

Mei-Kuang Chen, Weiya Xia, Qiongzhu Dong, Yi Du, Hung-Ling Wang, Coya Tapia, Yongkun Wei, Ye Han, Yu-Yi Chu, Clinton Yam, Yuan Gao, Yu-Han Wang, Funda Meric-Bernstam, Jinsong Liu, Shao-Chun Wang, Dihua Yu, Mien-Chie Hung

Cancer Res (2020) 80 (16_Supplement): 5682.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5682

Published: 15 August 2020

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Journal Articles

Abstract 4074: Reversing acquired PARPi resistance of TNBC through combined inhibition of cMet and EGFR

Yu Yi Chu, Clinton Yam, Mei-Kuang Chen, Li-Chuan Chan, Lei Nie, Mien-Chie Hung

Cancer Res (2020) 80 (16_Supplement): 4074.

DOI: https://doi.org/10.1158/1538-7445.AM2020-4074

Published: 15 August 2020

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Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity

Cancer Res (2020) 80 (11): 2298–2310.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3133

Published: 02 June 2020

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Includes: Supplementary data

Journal Articles

Abstract LB-092: TKI insensitive role of EGFRconfers TKI resistance via PKCδ

Pei-chih Lee, Mien-chie Hung

Cancer Res (2019) 79 (13_Supplement): LB-092.

DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-092

Published: 01 July 2019

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Journal Articles

Abstract LB-258: EGFR and c-MET cooperate to enhance PARP inhibitor resistance in hepatocellular carcinoma

Qiongzhu Dong, Yi Du, Xixi Zhao, Hui Li, Chunxiao Liu, Yongkun Wei, Mien-chie Hung

Cancer Res (2019) 79 (13_Supplement): LB-258.

DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-258

Published: 01 July 2019

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Journal Articles

Abstract 845: c-MET nuclear transportation via membrane-bounded retrograde trafficking in breast cancer cells

Mei-Kuang Chen, Yi Du, Linlin Sun, Jennifer L. Hsu, Yu-Han Wang, Yuan Gao, Jiaxing Huang, Mien-Chie Hung

Cancer Res (2019) 79 (13_Supplement): 845.

DOI: https://doi.org/10.1158/1538-7445.AM2019-845

Published: 01 July 2019

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Journal Articles

Abstract 4122: The regulatory mechanism of PD-L1 level through ER-associated degradation

Jong-Ho Cha, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Chia-Wei Li, Heng-Huan Lee, Mien-Chie Hung

Cancer Res (2019) 79 (13_Supplement): 4122.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4122

Published: 01 July 2019

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Journal Articles

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

Qiongzhu Dong, Yi Du, Hui Li, Chunxiao Liu, Yongkun Wei, Mei-Kuang Chen, Xixi Zhao, Yu-Yi Chu, Yufan Qiu, Lunxiu Qin, Hirohito Yamaguchi, Mien-Chie Hung

Cancer Res (2019) 79 (4): 819–829.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1273

Published: 15 February 2019

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Includes: Supplementary data

Journal Articles

Posttranslational Modifications of PD-L1 and Their Applications in Cancer Therapy

Jung-Mao Hsu, Chia-Wei Li, Yun-Ju Lai, Mien-Chie Hung

Cancer Res (2018) 78 (22): 6349–6353.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1892

Published: 15 November 2018

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Journal Articles

Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer

Cancer Res (2018) 78 (16): 4524–4532.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-0385

Published: 14 August 2018

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Includes: Supplementary data

Journal Articles

Juxtacrine Signaling Inhibits Antitumor Immunity by Upregulating PD-L1 Expression

Wen-Hao Yang, Jong-Ho Cha, Weiya Xia, Heng-Huan Lee, Li-Chuan Chan, Ying-Nai Wang, Jennifer L. Hsu, Guoxin Ren, Mien-Chie Hung

Cancer Res (2018) 78 (14): 3761–3768.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-0040

Published: 15 July 2018

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Journal Articles

Abstract 5606: Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1

Seung-Oe Lim, Chia-Wei Li, Mien-Chie Hung

Cancer Res (2018) 78 (13_Supplement): 5606.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5606

Published: 01 July 2018

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2 3 4 5

NARROW

Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function

AMBRA1 Promotes TGFβ Signaling via Nonproteolytic Polyubiquitylation of Smad4

Abstract LB097: MET inhibitor enhances efficacies of gemcitabine and olaparib in pancreatic cancer cells

Abstract 3081: Secretory human ribonuclease 1 functions as Eph receptor A4 ligand to promote breast tumor initiation

Abstract 120: Compartmentalized functions of epidermal growth factor receptor (EGFR) in tumorigenesis and malignant phenotypes

Abstract 1027: Inhibition of c-MET upregulates PD-L1 related immune escape in lung adenocarcinoma

Abstract 6527: Targeting glycosylated PD-1 induces potent anti-tumor immunity

Abstract 5180: Nuclear receptor tyrosine kinase c-MET restrains efficacy of PARP inhibitor in pancreatic cancer cells

Abstract 5682: Synergism of PARP inhibitor and MET inhibitor in multiple cancer types with intrinsic and acquired PARP inhibitor resistances

Abstract 4074: Reversing acquired PARPi resistance of TNBC through combined inhibition of cMet and EGFR

Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity

Abstract LB-092: TKI insensitive role of EGFRconfers TKI resistance via PKCδ

Abstract LB-258: EGFR and c-MET cooperate to enhance PARP inhibitor resistance in hepatocellular carcinoma

Abstract 845: c-MET nuclear transportation via membrane-bounded retrograde trafficking in breast cancer cells

Abstract 4122: The regulatory mechanism of PD-L1 level through ER-associated degradation

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

Posttranslational Modifications of PD-L1 and Their Applications in Cancer Therapy

Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer

Juxtacrine Signaling Inhibits Antitumor Immunity by Upregulating PD-L1 Expression

Abstract 5606: Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1

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