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Michelle Haber
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Journal Articles

Abstract A044 Enhanced disease detection using single cell RNAseq in children with brain cancer

Robert Salomon, Wenyan Li, Mojgan Toumari, Aileen Lowe, Chelsea Mayoh, Paulettte Barahona, Loretta MS Lau, Jordan Staunton, Erica Jacobson, Sumanth Nagabushan, Neevika Manoharan, Ruth Mitchell, Faustine Ong, Michelle Haber, David S Ziegler, Mark J. Cowley, Marion K. Mateos
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A044.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A044
Published: 05 September 2024
View articletitled, Abstract A044 Enhanced disease detection using single cell RNAseq in children with brain cancer
Journal Articles

Abstract B014: Increasing the clinical utility of transcriptome analysis in high-risk childhood precision oncology

Chelsea Mayoh, Paulette Barahona, Angela Lin, Lujing Cui, Pamela Ajuyah, Ann Altekoester, Loretta MS Lau, Dong-Anh Khuong-Quang, Vanessa Tyrrell, Michelle Haber, Marie Wong-Erasmus, Paul G. Ekert, Mark J. Cowley
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B014.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B014
Published: 05 September 2024
View articletitled, Abstract B014: Increasing the clinical utility of transcriptome analysis in high-risk childhood precision oncology
Journal Articles

Abstract B007: High-risk pediatric cancer models in zebrafish, mouse and short-term culture predict individual patient responses to therapy

Nadine Azzam, Jamie I. Fletcher, Nicole Melong, Loretta Lau, Emmy M. Dolman, Jie Mao, Gabor Tax, Roxanne Cadiz, Lissandra Tuzi, Alvin Kamili, Biljana Dumevska, Jinhan Xie, Jennifer A. Chan, Donna L. Senger, Stephanie A. Grover, David Malkin, Michelle Haber, Jason N. Berman
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B007.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B007
Published: 05 September 2024
View articletitled, Abstract B007: High-risk pediatric cancer models in zebrafish, mouse and short-term culture predict individual patient responses to therapy
Journal Articles

Abstract A045 Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours

Robert Salomon, Wenhan Chen, Charles Shale, Mojgan Toumari, Aileen Lowe, Wenyan Li, Jingwei Chen, Sajad Razavi Bazaz, Paulette Barahona, Louise Cui, Chelsea Mayoh, Sam El-Kamand, Vanessa Tryell, Marie Wong-Erasmus, Loretta M.S. Lau, Noemi Fuentes Bolanos, Edwin Cuppen, Dong Anh Khuong Quang, Jordan Staunton, Marion K. Mateos, Toby Trahair, Michelle Haber, David S Ziegler, Paul G. Ekert, Peter Priestley, Mark J. Cowley
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A045.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A045
Published: 05 September 2024
View articletitled, Abstract A045 Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours
Journal Articles

Abstract B012: Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors

Loretta M.S. Lau, Dong-Anh Khuong-Quang, Jordan Staunton, Nicholas Sanders, Shampavi Sriharan, Sarah Trinder, Neevika Manoharan, Paulette Barahona, Ann-Kristin Altekoester, Kimberley Dias, Megan Rumford, Dianne Sylvester, Jasmine Parhar, Marion K. Mateos, Marie Wong, Chelsea Mayoh, Mark J. Cowley, Paul G. Ekert, Michelle Haber, Vanessa Tyrrell, David S Ziegler
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B012.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B012
Published: 05 September 2024
View articletitled, Abstract B012: Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors
Journal Articles

Abstract 2673: Copper chelation overcomes the immunosuppressive neuroblastoma microenvironment to potentiate anti-GD2 antibody therapy

Jourdin R. Rouaen, Antonella Salerno, Fabio Luciani, Jayne Murray, Tyler Shai-Hee, Nicodemus Tedla, Michelle Haber, Toby N. Trahair, Orazio Vittorio
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2673.
https://doi.org/10.1158/1538-7445.AM2024-2673
Published: 22 March 2024
View articletitled, Abstract 2673: Copper chelation overcomes the immunosuppressive neuroblastoma microenvironment to potentiate anti-GD2 antibody therapy
Journal Articles

High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer

Chelsea Mayoh, Jie Mao, Jinhan Xie, Gabor Tax, Shu-Oi Chow, Roxanne Cadiz, Karina Pazaky, Paulette Barahona, Pamela Ajuyah, Peter Trebilcock, Angela Malquori, Kate Gunther, Anica Avila, Doo Young Yun, Stephanie Alfred, Anjana Gopalakrishnan, Alvin Kamili, Marie Wong, Mark J. Cowley, Sophie Jessop, Loretta M.S. Lau, Toby N. Trahair, David S. Ziegler, Jamie I. Fletcher, Andrew J. Gifford, Maria Tsoli, Glenn M. Marshall, Michelle Haber, Vanessa Tyrrell, Timothy W. Failes, Greg M. Arndt, Richard B. Lock, Paul G. Ekert, M. Emmy M. Dolman
Journal: Cancer Research
Cancer Res (2023) 83 (16): 2716–2732.
https://doi.org/10.1158/0008-5472.CAN-22-3702
Published: 15 August 2023
View articletitled, High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
Open the PDF for High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4670: True bench-to-bedside science: An international pilot study modeling hard-to-cure pediatric cancers to prioritize therapeutic intervention

Nadine Azzam, Nicole Melong, Lissandra Tuzi, Lisa Pinto, Jamie I. Fletcher, Alvin Kamili, Biljana Dumevska, Loretta Lau, Jennifer A. Chan, Donna L. Senger, Stephanie A. Grover, Michelle Haber, David Malkin, Jason N. Berman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4670.
https://doi.org/10.1158/1538-7445.AM2023-4670
Published: 04 April 2023
View articletitled, Abstract 4670: True bench-to-bedside science: An international pilot study modeling hard-to-cure pediatric cancers to prioritize therapeutic intervention
Journal Articles

Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers

Chelsea Mayoh, Rachael L. Terry, Marie Wong, Loretta M. Lau, Dong Anh Khuong-Quang, Marion K. Mateos, Vanessa Tyrrell, Michelle Haber, David S. Ziegler, Mark J. Cowley, Joseph A. Trapani, Paul J. Neeson, Paul G. Ekert
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3044.
https://doi.org/10.1158/1538-7445.AM2021-3044
Published: 01 July 2021
View articletitled, Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers
Journal Articles

Abstract 639: Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR

Vinod Vijay Subhash, Alvin Kamili, Marie-Wong Erasmus, Dan Chen, Libby Huang, Vanessa Tyrell, Caroline Atkinson, Nicola Venn, Mark Cowley, Glenn Marshall, Paul Ekert, Michelle Henderson, Rosemary Sutton, Murray Norris, Michelle Haber, Jamie Fletcher, Toby Trahair
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 639.
https://doi.org/10.1158/1538-7445.AM2021-639
Published: 01 July 2021
View articletitled, Abstract 639: Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR
Journal Articles

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

Florida Voli, Emanuele Valli, Luigi Lerra, Kathleen Kimpton, Federica Saletta, Federico M. Giorgi, Daniele Mercatelli, Jourdin R.C. Rouaen, Sylvie Shen, Jayne E. Murray, Aria Ahmed-Cox, Giuseppe Cirillo, Chelsea Mayoh, Paul A. Beavis, Michelle Haber, Joseph A. Trapani, Maria Kavallaris, Orazio Vittorio
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4129–4144.
https://doi.org/10.1158/0008-5472.CAN-20-0471
Published: 02 October 2020
View articletitled, Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Open the PDF for Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion in another window
Includes: Supplementary data
Journal Articles

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression

Jixuan Gao, MoonSun Jung, Chelsea Mayoh, Pooja Venkat, Katherine M. Hannan, Jamie I. Fletcher, Alvin Kamili, Andrew J. Gifford, Eric P. Kusnadi, Richard B. Pearson, Ross D. Hannan, Michelle Haber, Murray D. Norris, Klaartje Somers, Michelle J. Henderson
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3706–3718.
https://doi.org/10.1158/0008-5472.CAN-19-3914
Published: 02 September 2020
View articletitled, Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression
Open the PDF for Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract SY09-02: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia

Michelle Haber, Mark J. Cowley, Paul Ekert, Loretta Lau, Emily Mould, ZCC PRISM Omics Core, ZCC Prelinical Drug Testing Core, Andrew Gifford, Richard B. Lock, Glenn M. Marshall, Murray D. Norris, Tracey O'Brien, Dong Anh Khuong Quang, David Thomas, Toby Trahair, Katherine Tucker, David S. Ziegler, Vanessa Tyrrell
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): SY09-02.
https://doi.org/10.1158/1538-7445.AM2020-SY09-02
Published: 15 August 2020
View articletitled, Abstract SY09-02: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia
Journal Articles

Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma

Caroline Atkinson, Carole Tactacan, Alvin Kamili, Federica Saletta, Christine Gana, Georgina Eden, Chelsea Mayoh, Richard Lock, Murray Norris, Michelle Haber, Andrew Gifford, Toby Trahair, Jamie Fletcher
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A35.
https://doi.org/10.1158/1538-7445.PEDCA19-A35
Published: 15 July 2020
View articletitled, Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma
Journal Articles

Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies

Michelle Haber, Laura Gamble, Lin Xiao, Ruby Pandher, Klaartje Somers, Jayne Murray, Aaminah Khan, Denise Yu, Laura Franshaw, Mark R. Burns, Maria Tsoli, Anahid Ehteda, Anthony Cesare, Aisling O’Connor, Francis Mussai, Carmela de Santo, Paul Cheng, Lioubov Korotchkina, Katerina Gurova, Vanessa Tyrrell, Emily Mould, Loretta Lau, Dong Anh Khuong Quang, Chelsea Mayoh, Greg Arndt, Paulette Barahona, Tim Failes, Jamie Fletcher, Noemi Fuentes- Bolanos, Marie-Emilie Gauthier, Andrew Gifford, Dylan Grebert-Wade, Alvin Kamili, Amit Kumar, Sumanth Nagabushan, Tracey O’Brien, Patrick Strong, Alexandra Sherstyuk, David Thomas, Toby Trahair, Katherine Tucker, Meera Warby, Marie Wong, Jinhan Xie, Kathryn Evans, Richard Lock, Olga B. Chernova, Michelle Henderson, Andrei V Gudkov, Paul Ekert, Mark J. Cowley, Glenn M. Marshall, David S. Ziegler, Murray D. Norris
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): IA13.
https://doi.org/10.1158/1538-7445.PEDCA19-IA13
Published: 15 July 2020
View articletitled, Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies
Journal Articles

Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer

Paulette Barahona, Alexandra Sherstyuk, Mark Cowley, Paul Ekert, Judy Kirk, Dong-Anh Khuong-Quang, Amit Kumar, Loretta Lau, Chelsea Mayoh, Glenn Marshall, Emily Moud, Tracey O’Brien, Mark Pinese, David Thomas, Vanessa Tyrell, David Ziegler, Michelle Haber, Katherine Tucker, Noemi Auxiliadora Fuentes-Bolanos, Meera Warby
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A03.
https://doi.org/10.1158/1538-7445.PEDCA19-A03
Published: 15 July 2020
View articletitled, Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer
Journal Articles

Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer

Paulette Barahona, Jamie Fletcher, Noemi Fuentes-Bolanos, Marie-Emilie Gauthier, Michelle Haber, Richard B. Lock, Glenn M. Marshall, Chelsea Mayoh, Emily Mould, Sumanth Nagabushan, Murray Norris, Tracey O’Brien, Alexandra Sherstyuk, David Thomas, Toby Trahair, Katherine Tucker, Meera Warby, Marie Wong, David S. Ziegler, Vanessa J. Tyrrell, Paul Ekert, Mark J. Cowley, Loretta Lau, Dong-Anh Khuong Quang, Zero Childhood Cancer Program National Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A52.
https://doi.org/10.1158/1538-7445.PEDCA19-A52
Published: 15 July 2020
View articletitled, Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer
Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View articletitled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Open the PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface in another window
Includes: Supplementary data
Journal Articles

Abstract 3111: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer

Emily V. Mould, Loretta Lau, Greg Arndt, Paulette Barahona, Mark J. Cowley, Paul Ekert, Tim Failes, Jamie Fletcher, Andrew Gifford, Dylan Grebert-Wade, Michelle Haber, Alvin Kamili, Amit Kumar, Richard B. Lock, Glenn M. Marshall, Chelsea Mayoh, Murray Norris, Tracey O'Brien, Dong Anh Khuong Quang, Patrick Strong, Alexandra Sherstyuk, Toby Trahair, Maria Tsoli, Katherine Tucker, Meera Warby, Marie Wong, Jinhan Xie, David S. Ziegler, Vanessa Tyrrell
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3111.
https://doi.org/10.1158/1538-7445.AM2019-3111
Published: 01 July 2019
View articletitled, Abstract 3111: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer
Journal Articles

Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma

Zsuzsanna Nagy, Maxwell Kanikevich, Jessica Koach, Chelsea Mayoh, Daniel Carter, Tao Liu, Yanhua Du, Cizhong Jiang, Michelle Haber, Murray Norris, Belamy Cheung, Glenn Marshall
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3659.
https://doi.org/10.1158/1538-7445.AM2019-3659
Published: 01 July 2019
View articletitled, Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma