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Michail Ignatiadis
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Journal Articles

Abstract PO3-13-02: Genomic and intrinsic subtype correlates of serum thymidine kinase activity in patients with metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial

Svitlana Tyekucheva, Thayane Crestani, Michail Ignatiadis, Patrick Neven, Marco Colleoni, Stéphanie Henry, Konstantinos Papadimitriou, Antonio Bernardo, Elena Seles, Francois Duhoux, Iain Macpherson, Alastair Thomson, David Mark Davies, Mattias Bergqvist, Ilenia Migliaccio, Gabriele Zoppoli, Roswitha Kammler, Heidi De Swert, Barbara Ruepp, Angel Guerrero, Arnau Llinas, Danai Fimereli, Amal Arahmani, David Cameron, Sherene Loi, Martine Piccart, Meredith Regan, Matteo Benelli, Luca Malorni
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-13-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-13-02
Published: 02 May 2024
View article titled, Abstract PO3-13-02: Genomic and intrinsic subtype correlates of serum thymidine kinase activity in patients with metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial
Journal Articles

Abstract PO2-16-02: RBsig gene-expression signature in patients with endocrine resistant metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial

Matteo Benelli, Svitlana Tyekucheva, Thayane Crestani, Michail Ignatiadis, Patrick Neven, Marco Colleoni, Stéphanie Henry, Konstantinos Papadimitriou, Antonio Bernardo, Elena Seles, François Duhoux, Iain Macpherson, Alastair Thomson, David Mark Davies, Ilenia Migliaccio, Gabriele Zoppoli, Roswitha Kammler, Heidi De Swert, Barbara Ruepp, Philippe Aftimos, Jose Seoane, Dario Romagnoli, David Venet, Theodora Goulioti, David Cameron, Sherene Loi, Martine Piccart, Meredith Regan, Luca Malorni
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-16-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-16-02
Published: 02 May 2024
View article titled, Abstract PO2-16-02: RBsig gene-expression signature in patients with endocrine resistant metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial
Journal Articles

Abstract GS01-03: Adding atezolizumab to adjuvant chemotherapy for stage II and III triple-negative breast cancer is unlikely to improve efficacy: interim analysis of the ALEXANDRA/IMpassion030 phase 3 trial

Michail Ignatiadis, Andrew Bailey, Heather McArthur, Sarra El-Abed, Evandro de Azambuja, Otto Metzger, Steve Chui, Max Dieterich, Thomas Perretti, Guenther Steger, Jacek Jassem, Soo Chin Lee, Michaela Higgins, José Zarbá, Marcus Schmidt, Henry Gomez, Angel Guerrero-Zotano, Luca Moscetti, Joanne Win Yang Chiu, Carter DuFrane, Vanessa Honvault, Rosa Altarcheh, Luciana Molinero, Andrew Ellingson, Elisabetta Munzone, Noa Efrat Ben-Baruch, Emilio Bajetta, Shinji Ohno, Seock-Ah Im, Gustavo Werutsky, Einav Gal-Yam, Xavier Gonzalez-Farré, Ling-Ming Tseng, William Jacot, Oleg Gluz, Zhimin Shao, Yaroslav Shparyk, Ivan Sinielnikov, Zimina Anastasia, Aleksandr Vasiliev, Esther Shearer-Kang, Eric Winer, Diogo Martins-Branco, Shona Fielding, David Cameron, Giuseppe Viale, Shigehira Saji, Richard Gelber, Martine Piccart
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): GS01-03.
https://doi.org/10.1158/1538-7445.SABCS23-GS01-03
Published: 02 May 2024
View article titled, Abstract GS01-03: Adding atezolizumab to adjuvant chemotherapy for stage II and III triple-negative breast cancer is unlikely to improve efficacy: interim analysis of the ALEXANDRA/IMpassion030 phase 3 trial
Journal Articles

Abstract GS02-13: Pregnancy after breast cancer in young women with germline BRCA pathogenic variants: results from an international cohort study

Matteo Lambertini, Eva Blondeaux, Elisa Agostinetto, Anne-Sophie Hamy-Petit, Hee Jeong Kim, Camila Chiodi, Rinat Bernstein-Molho, Florentine Hilbers, Katarzyna Pogoda, Estela Carrasco Lopez, Kevin Punie, Jyoti Bajpai, Michail Ignatiadis, Halle Moore, Kelly-Anne Phillips, Angela Toss, Christine Rousset-Jablonski, Fedro Alessandro Peccatori, Tiphaine Renaud, Alberta Ferrari, Shani Paluch-Shimon, Robert Fruscio, Wanda Cui, Stephanie Wong, Claudio Vernieri, Kathryn Ruddy, Maria Vittoria Dieci, Alexios Matikas, Mariya Rozenblit, Cynthia Villareal Garza, Laura De Marchis, Lucia Del Mastro, Fabio Puglisi, Maria Del Pilar Estevez-Diz, Kenny A. Rodriguez-Wallberg, Bela Mrinakova, Sarah Meister, Luca Livraghi, Florian Clatot, Rinat Yerushalmi, Carmine De Angelis, Rodrigo Sánchez-Bayona, Icro Meattini, Natalia Cichowska-Cwalińska, Martine Berlière, Mahmoud Salama, Ugo De Giorgi, Amir Sonnenblick, Hatem Azim, Ann Partridge
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): GS02-13.
https://doi.org/10.1158/1538-7445.SABCS23-GS02-13
Published: 02 May 2024
View article titled, Abstract GS02-13: Pregnancy after breast cancer in young women with germline BRCA pathogenic variants: results from an international cohort study
Journal Articles

Abstract OT1-18-02: First-line chemo-immunotherapy with durvalumab, paclitaxel and carboplatin with or without anti-CD73 antibody oleclumab in advanced or metastatic triple-negative breast cancer: Preliminary results of the randomized phase II SYNERGY trial

Veronique Debien, Christian Maurer, Philippe Aftimos, Florian Clatot, Delphine Loirat, Kevin Punie, François Ghiringhelli, Anhony Gonçalves, Donatienne Taylor, Tom Van den Mooter, Jean-Marc Ferrero, Hervé Bonnefoi, Jean-Luc Canon, François Duhoux, Renaud Poncin, Fernando Bazan, Nicolas Isambert, Philippe Barthelemy, Mariana Brandão, Paulus Kristanto, Michail Ignatiadis, Martine Piccart, Laurence Buisseret
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT1-18-02.
https://doi.org/10.1158/1538-7445.SABCS21-OT1-18-02
Published: 15 February 2022
View article titled, Abstract OT1-18-02: First-line chemo-immunotherapy with durvalumab, paclitaxel and carboplatin with or without anti-CD73 antibody oleclumab in advanced or metastatic triple-negative breast cancer: Preliminary results of the randomized phase II SYNERGY trial
Journal Articles

Abstract P2-01-06: Detection of circulating tumor DNA post neoadjuvant chemotherapy using a personalized assay is associated with disease relapse

Elisa Agostinetto, Frédéric Cailleux, Matteo Lambertini, Françoise Rothé, Hsin-Ta Wu, Mustafa Balcioglu, Himanshu Sethi, Delphine Vincent, Giulia Viglietti, Andrea Gombos, Andreas Papagiannis, Isabelle Veys, Ahmad Awada, Christos Sotiriou, Ekaterina Kalashnikova, Alexey Aleshin, Denis Larsimont, David Venet, Michail Ignatiadis
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-01-06.
https://doi.org/10.1158/1538-7445.SABCS21-P2-01-06
Published: 15 February 2022
View article titled, Abstract P2-01-06: Detection of circulating tumor DNA post neoadjuvant chemotherapy using a personalized assay is associated with disease relapse
Journal Articles

Abstract GS4-08: Clinical utility of repeated circulating tumor cell (CTC) enumeration as early treatment monitoring tool in metastatic breast cancer (MBC) - a global pooled analysis with individual patient data

Wolfgang J Janni, Tracy C. Yab, Daniel F. Hayes, Massimo Cristofanilli, Francois-Clement Bidard, Michail Ignatiadis, Meredith M. Regan, Catherine Alix-Panabières, William E. Barlow, Carlos Caldas, Lisa A. Carey, Luc Dirix, Tanja Fehm, Jose A. Garcia-Saenz, Paola Gazzaniga, Daniele Generali, Lorenzo Gerratana, Rafael Gisbert-Criado, William Jacot, Zefei Jiang, Evi Lianidou, Mark J.M. Magbanua, Luis Manso, Dimitrios Mavroudis, Volkmar Müller, Elisabetta Munzone, Klaus Pantel, Jean-Yves Pierga, Brigitte Rack, Sabine Riethdorf, Hope S. Rugo, Kostandinos Sideras, Stefan Sleijfer, Jeffrey Smerage, Justin Stebbing, Leon W.M.M. Terstappen, José Vidal-Martínez, Rita Zamarchi, Karthik Giridhar, Thomas W.P. Friedl, Minetta C. Liu
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): GS4-08.
https://doi.org/10.1158/1538-7445.SABCS20-GS4-08
Published: 15 February 2021
View article titled, Abstract GS4-08: Clinical utility of repeated circulating tumor cell (CTC) enumeration as early treatment monitoring tool in metastatic breast cancer (MBC) - a global pooled analysis with individual patient data
Journal Articles

Abstract PS5-05: Serum thymidine kinase activity in patients with luminal metastatic breast cancer treated with palbociclib and fulvestrant within the PYTHIA trial

Luca Malorni, Svitlana Tyekucheva, Florentine S Hilbers, Michail Ignatiadis, Patrick Neven, Marco Colleoni, Stéphanie Henry, Alberto Ballestrero, Andrea Bonetti, Guy Jerusalem, Konstantinos Papadimitriou, Antonio Bernardo, Francois Duhoux, Iain MacPherson, Alastair Thomson, David Mark Davies, Mattias Bergqvist, Matteo Benelli, Amelia McCartney, Heidi De Swert, Barbara Ruepp, Manuela Rabaglio, Rudolf Maibach, Martine Piccart, Meredith M Regan
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS5-05.
https://doi.org/10.1158/1538-7445.SABCS20-PS5-05
Published: 15 February 2021
View article titled, Abstract PS5-05: Serum thymidine kinase activity in patients with luminal metastatic breast cancer treated with palbociclib and fulvestrant within the PYTHIA trial
Journal Articles

Abstract P1-19-22: Pearl or the use of FDG positron emission tomography imaging as an early dynamic biomarker of everolimus efficacy in advanced luminal breast cancer

Andrea Gombos, Martine Piccart-Gebhart, Lieveke Ameye, Peter Vuylsteke, Patrick Neven, Vincent Richard, Francois P Duhoux, Marianne Paesmans, Michail Ignatiadis, Patrick Flamen, Géraldine Gebhart
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-19-22.
https://doi.org/10.1158/1538-7445.SABCS19-P1-19-22
Published: 15 February 2020
View article titled, Abstract P1-19-22: Pearl or the use of FDG positron emission tomography imaging as an early dynamic biomarker of everolimus efficacy in advanced luminal breast cancer
Journal Articles

Abstract P3-01-13: Association between the histopathological growth patterns (HGP) of liver metastases (LM) and survival after hepatic surgery in patients with oligometastatic breast cancer (BC)

Peter B Vermeulen, Ali Bohlok, Sophia Leduc, François Richard, Lara Botzenhart, Michail Ignatiadis, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Alain Hendlisz, Steven Van Laere, Luc Y Dirix, Jean-Christophe Noël, Valerio Lucidi, Elia Biganzoli, Denis Larsimont, Christine Desmedt, Vincent Donckier
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-01-13.
https://doi.org/10.1158/1538-7445.SABCS19-P3-01-13
Published: 15 February 2020
View article titled, Abstract P3-01-13: Association between the histopathological growth patterns (HGP) of liver metastases (LM) and survival after hepatic surgery in patients with oligometastatic breast cancer (BC)
Journal Articles

Promises and Pitfalls of Using Liquid Biopsy for Precision Medicine

Giovanna Rossi, Michail Ignatiadis
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2798–2804.
https://doi.org/10.1158/0008-5472.CAN-18-3402
Published: 03 June 2019
View article titled, Promises and Pitfalls of Using Liquid Biopsy for Precision Medicine
Open the PDF for Promises and Pitfalls of Using Liquid Biopsy for Precision Medicine in another window
Journal Articles

Abstract 3698: Unraveling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis

Yacine Bareche, David Venet, Philippe Aftimos, Michail Ignatiadis, Martine Piccart, Francoise Rothe, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3698.
https://doi.org/10.1158/1538-7445.AM2018-3698
Published: 01 July 2018
View article titled, Abstract 3698: Unraveling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis
Journal Articles

Abstract 3962: Circulating tumor DNA (ctDNA) as an alternative to tumor biopsies for precision oncology: The Jules Bordet Institute experience

Philippe G. Aftimos, Marion Maetens, Françoise Rothé, David Brown, Yacine Barèche, Alexandre Irrthum, Thierry Berghmans, Joseph Kerger, Alain Hendlisz, Michail Ignatiadis, Martine Piccart, Christos Sotiriou, Ahmad Awada
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3962.
https://doi.org/10.1158/1538-7445.AM2016-3962
Published: 15 July 2016
View article titled, Abstract 3962: Circulating tumor DNA (ctDNA) as an alternative to tumor biopsies for precision oncology: The Jules Bordet Institute experience
Journal Articles

Abstract 3968: Comparison of NGS and digital PCR for the detection of point mutations in breast tumor and plasma samples

Françoise Rothé, Ghizlane Rouas, Michelle Coureau, Marion Maetens, David Brown, Christos Sotiriou, Michail Ignatiadis
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3968.
https://doi.org/10.1158/1538-7445.AM2016-3968
Published: 15 July 2016
View article titled, Abstract 3968: Comparison of NGS and digital PCR for the detection of point mutations in breast tumor and plasma samples
Journal Articles

Abstract P4-01-01: Circulating tumor cell (CTC) enumeration and HER2 assessment as predictors of breast cancer outcomes in the ALTTO (BIG 2-06, Alliance N063D) Trial

Minetta C Liu, Brigitte Rack, Amylou C Dueck, David W Hillman, Michael B Campion, Monica M Reinholz, Kevin C Halling, Christos Sotiriou, Françoise Rothé, Marion Maetens, Ghizlane Rouas, Wolfgang Janni, Antonio C Wolff, Lyndsay N Harris, Julie R Gralow, Kathleen I Pritchard, Susan Ellard, Nguyet A Le-Lindqwister, Frances Boyle, Evandro De Azambuja, Martine J Piccart-Gebhart, Michail Ignatiadis, Edith A Perez
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P4-01-01.
https://doi.org/10.1158/1538-7445.SABCS14-P4-01-01
Published: 01 May 2015
View article titled, Abstract P4-01-01: Circulating tumor cell (CTC) enumeration and HER2 assessment as predictors of breast cancer outcomes in the ALTTO (BIG 2-06, Alliance N063D) Trial
Journal Articles

Abstract OT1-2-02: Trastuzumab in HER2-negative early breast cancer as adjuvant treatment for circulating tumor cells (CTCs) (Treat CTC)

Michail Ignatiadis, Carlo Messina, Saskia Litiere, Dimitris Mavroudis, Christian Dittrich, Anthony Kong, Wolfgang Janni, Christos Sotiriou, Martine Piccart, Jean-Yves Pierga, Brigitte Rack
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): OT1-2-02.
https://doi.org/10.1158/1538-7445.SABCS14-OT1-2-02
Published: 01 May 2015
View article titled, Abstract OT1-2-02: Trastuzumab in HER2-negative early breast cancer as adjuvant treatment for circulating tumor cells (CTCs) (Treat CTC)
Journal Articles

Abstract PD3-7: Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analyses in breast cancer

Michail Ignatiadis, Françoise Rothe, Jean-François Laes, Diether Lambrechts, Dominiek Smeets, Delphine Vincent, Marion Maetens, Debora Fumagalli, Stefan Michiels, Stylianos Drisis, Carine Moerman, Jean-Pol Detiffe, Denis Larsimont, Ahmad Awada, Martine Piccart, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): PD3-7.
https://doi.org/10.1158/1538-7445.SABCS14-PD3-7
Published: 01 May 2015
View article titled, Abstract PD3-7: Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analyses in breast cancer
Journal Articles

Abstract 986: Unraveling breast cancer progression through geographical and temporal sequencing

Christine Desmedt, David Brown, Borbala Szekely, Dominiek Smeets, Marcell A. Szasz, Pierre-Yves Adnet, Françoise Rothé, Zsofia I. Nagy, Zsofia Farago, Anna-Maria Tokes, Dimitrios Zardavas, Gabriele Zoppoli, Michail Ignatiadis, Lajos Pusztai, Martine Piccart, Denis Larsimont, Diether Lambrechts, Janina Kulka, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 986.
https://doi.org/10.1158/1538-7445.AM2014-986
Published: 01 October 2014
View article titled, Abstract 986: Unraveling breast cancer progression through geographical and temporal sequencing
Journal Articles

Abstract 839: HER2 expression occurs early in breast cancer dissemination

Michail Ignatiadis, Virginie Durbecq, Isabelle Veys, Jose Rosari, Carmen Criscitiello, Philippe Bedard, Sandeep K. Singhal, Frédéric Buxant, Carole Chaboteaux, Rouas Ghizlane, Denis Larsimont, Fabienne Liebens, Martine Piccart, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 839.
https://doi.org/10.1158/1538-7445.AM10-839
Published: 15 April 2010
View article titled, Abstract 839: HER2 expression occurs early in breast cancer dissemination
Journal Articles

Abstract #2743: Gene expression module associated with Insulin-like Growth Factor 1 (IGF1) pathway activation predicts poor response to tamoxifen in women with ER+/HER2- early breast cancer (BC).

Michail Ignatiadis, Benjamin Haibe-Keins, Philippe Bedard, Sandeep Singhal, Francoise Lallemand, Christine Desmedt, Fátima Cardoso, Marine Piccart, Christos Sotiriou
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2743.
Published: 01 May 2009
View article titled, Abstract #2743: Gene expression module associated with Insulin-like Growth Factor 1 (IGF1) pathway activation predicts poor response to tamoxifen in women with ER+/HER2- early breast cancer (BC).