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Journal Articles

Abstract 3197: Macrophage-ferritin-drug conjugates: a novel approach to overcome glioblastoma drug resistance and induce long-term tumor immunity

Maciej Białasek, Miaomiao Sun, Bartłomiej Taciak, Tomasz Rygiel, Michael Weller, Tobias Weiss, Magdalena Krol

Cancer Res (2025) 85 (8_Supplement_1): 3197.

https://doi.org/10.1158/1538-7445.AM2025-3197

Published: 21 April 2025

View articletitled, Abstract 3197: Macrophage-ferritin-drug conjugates: a novel approach to overcome glioblastoma drug resistance and induce long-term tumor immunity

Journal Articles

Abstract 4781: Generation and in vivo characterization of a novel antibody targeting Prostatic Acid Phosphatase (ACP-3)

Claudia Comacchio, Stefanie Pfister, Domenico Ravazza, Samuele Cazzamalli, Ettore Gilardoni, Emanuele Puca, Tobias Weiss, Michael Weller, Dario Neri, Roberto De Luca

Cancer Res (2025) 85 (8_Supplement_1): 4781.

https://doi.org/10.1158/1538-7445.AM2025-4781

Published: 21 April 2025

View articletitled, Abstract 4781: Generation and in vivo characterization of a novel antibody targeting Prostatic Acid Phosphatase (ACP-3)

Journal Articles

Abstract CT230: Exploratory analyses of MGMT promoter methylation and PD-L1 expression from newly diagnosed glioblastoma patients in CheckMate 548 study suggest refinement in thresholds for predicting response to standard of care and nivolumab treatments

Yu-Han Hung, Aparna Chhibber, Michael Lim, Michael Weller, David A. Reardon, Antonio Omuro, Keith L. Ligon, Ana Lako, Ann Forslund

Cancer Res (2024) 84 (7_Supplement): CT230.

https://doi.org/10.1158/1538-7445.AM2024-CT230

Published: 05 April 2024

View articletitled, Abstract CT230: Exploratory analyses of MGMT promoter methylation and PD-L1 expression from newly diagnosed glioblastoma patients in CheckMate 548 study suggest refinement in thresholds for predicting response to standard of care and nivolumab treatments

Journal Articles

The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen

Tathiane M. Malta, Thais S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S. Barnholtz-Sloan, Hui K. Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C.M. Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila M. Poisson, Consortium The GLASS, Adelheid Woehrer, Allison K Lowman, Ana C deCarvalho, Ana Valeria Castro, Andrea Transou, Andrew R Brodbelt, Ann-Christin Hau, Anna Lasorella, Anna Golebiewska, Annemiek Walenkamp, Annette M Molinaro, Antonio Iavarone, Azzam Ismail, Bart A Westerman, Bauke Ylstra, Christoph Bock, D. Ryan Ormond, Daniel J Brat, Emre Kocakavuk, Erwin G Van Meir, Floris P Barthel, Frederick S Varn, Fulvio D'Angelo, Gaetano Finocchiaro, Ganesh Rao, Gelareh Zadeh, Guido Reifenberger, Ho Keu ngNg, Hoon Kim, Houtan Noushmehr, Hrvoje Miletic, Hui K Gan, Indrani Datta, Jack Rock, James M Snyder, Jason T Huse, Jennifer M Connelly, Jill S Barnholtz-Sloan, Johanna M Niers, John F deGroot, Kadir C Akdemir, Kasthuri S Kannan, Keith L Ligon, Kenneth Aldape, Ketan R Bulsara, Kevin C Johnson, Kristin D Alfaro, Laila M Poisson, Luciano Garofano, Lucy F Stead, MacLean P Nasrallah, Marion Smits, Martin J van den Bent, Mathilde CM Kouwenhoven, Michael Weller, Mohammad Hasanain, Mustafa Khasraw, Peter V Gould, Peter A Sillevis Smitt, Peter S LaViolette, Philip D Tatman, Pieter Wesseling, Pim J French, Rameen Beroukhim, Roel G.W. Verhaak, Simona Migliozzi, Simone P Niclou, Spyridon Bakas, Steven Kalkanis, Sun Ha Paek, Susan C Short, Tabatabai Ghazaleh, Tathiane M Malta, Thais S Sabedot, Tobias Weiss, Tobias Walbert, Ujjwal Baid, Wies Vallentgoed, W. K. Alfred Yung, Roel G.W. Verhaak, Antonio Iavarone, Houtan Noushmehr

Cancer Res (2024) 84 (5): 741–756.

https://doi.org/10.1158/0008-5472.CAN-23-2093

Published: 04 March 2024

View articletitled, The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen

Includes: Supplementary data

Journal Articles

Abstract CT062: GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

Cancer Res (2023) 83 (8_Supplement): CT062.

https://doi.org/10.1158/1538-7445.AM2023-CT062

Published: 14 April 2023

View articletitled, Abstract CT062: GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

Journal Articles

Abstract 1991: Characterization of the exome, transcriptome, and immunopeptidome to map alterations in primary and recurrent glioblastoma

Cancer Res (2022) 82 (12_Supplement): 1991.

https://doi.org/10.1158/1538-7445.AM2022-1991

Published: 15 June 2022

View articletitled, Abstract 1991: Characterization of the exome, transcriptome, and immunopeptidome to map alterations in primary and recurrent glioblastoma

Journal Articles

Abstract 1375: The intra-tumoral spatial heterogeneity of T-cell antigens in glioblastoma: An integrated multi-omics approach

Marcel Wacker, Gioele Medici, Marissa Dubbelaar, Jens Bauer, Annika Nelde, Luca Regli, Michael Weller, Helmut R. Salih, Hans-Georg Rammensee, Marian C. Neidert, Juliane S. Walz

Cancer Res (2022) 82 (12_Supplement): 1375.

https://doi.org/10.1158/1538-7445.AM2022-1375

Published: 15 June 2022

View articletitled, Abstract 1375: The intra-tumoral spatial heterogeneity of T-cell antigens in glioblastoma: An integrated multi-omics approach

Journal Articles

Abstract 5325: Image-based functional precision medicine for repurposing neuroactive drugs in glioblastoma

Sohyon Lee, Tobias Weiss, Marcel Bühler, Rebekka Wegmann, Julien Mena, Michel Bihl, Sandra Goetze, Audrey van Drogen, Elisabeth J. Rushing, Bernd Wollscheid, Michael Weller, Berend Snijder

Cancer Res (2022) 82 (12_Supplement): 5325.

https://doi.org/10.1158/1538-7445.AM2022-5325

Published: 15 June 2022

View articletitled, Abstract 5325: Image-based functional precision medicine for repurposing neuroactive drugs in glioblastoma

Journal Articles

Abstract 2168: Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

Cancer Res (2022) 82 (12_Supplement): 2168.

https://doi.org/10.1158/1538-7445.AM2022-2168

Published: 15 June 2022

View articletitled, Abstract 2168: Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

Journal Articles

Abstract LB-055: Novel therapeutic option targeting the tumor cell lysosomes

Vadim Le Joncour, Pauliina Filppu, Minna Holopainen, Maija Hyvönen, S. Pauliina Turunen, Harri Sihto, Isabel Burghardt, Juha Jääskeläinen, Michael Weller, Kaisa Lehti, Reijo Käkela, Pirjo Laakkonen

Cancer Res (2020) 80 (16_Supplement): LB-055.

https://doi.org/10.1158/1538-7445.AM2020-LB-055

Published: 15 August 2020

View articletitled, Abstract LB-055: Novel therapeutic option targeting the tumor cell lysosomes

Journal Articles

Abstract 4886: Patients with EGFR amplification but without EGFRvIII expression have improved benefit compared to those with EGFRvIII expression in samples of the INTELLANCE2/EORTC1410 randomized phase II trial

Pim J. French, Johan M. Kros, Iris de Heer, Marica Eoli, Juan Manuel Sepulvada, Annemiek Walenkamp, Jean-Sebastian Frenel, Alba Brandes, Paul Clement, Michael Weller, Peter Ansell, Jim Looman, Earle Bain, Lisa Roberts-Rapp, Marie Morfouace, Thierry Gorlia, Vassilis Golfinopoulos, Martin van den Bent

Cancer Res (2019) 79 (13_Supplement): 4886.

https://doi.org/10.1158/1538-7445.AM2019-4886

Published: 01 July 2019

View articletitled, Abstract 4886: Patients with EGFR amplification but without EGFRvIII expression have improved benefit compared to those with EGFRvIII expression in samples of the INTELLANCE2/EORTC1410 randomized phase II trial

Journal Articles

Abstract 4: Antitumor activity of DLX1008, a single chain antibody fragment binding to VEGF-A, in in vivo preclinical models of Kaposi sarcoma and glioblastoma

Anthony B. Eason, Sang-Hoon Sin, Emese Szabó, Douglas J. Phillips, Miriam Droste, Abdijapar Shamshiev, Dirk P. Dittmer, Michael Weller

Cancer Res (2018) 78 (13_Supplement): 4.

https://doi.org/10.1158/1538-7445.AM2018-4

Published: 01 July 2018

View articletitled, Abstract 4: Antitumor activity of DLX1008, a single chain antibody fragment binding to VEGF-A, in in vivo preclinical models of Kaposi sarcoma and glioblastoma

Journal Articles

NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma

Tobias Weiss, Michael Weller, Matthias Guckenberger, Charles L. Sentman, Patrick Roth

Cancer Res (2018) 78 (4): 1031–1043.

https://doi.org/10.1158/0008-5472.CAN-17-1788

Published: 14 February 2018

View articletitled, NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma

Includes: Supplementary data

Journal Articles

Abstract 1504: Tumor-treating fields (TTFields) interfere with biological key properties of glioma cells in vitro

Manuela Silginer, Michael Weller, Roger Stupp, Patrick Roth

Cancer Res (2017) 77 (13_Supplement): 1504.

https://doi.org/10.1158/1538-7445.AM2017-1504

Published: 01 July 2017

View articletitled, Abstract 1504: Tumor-treating fields (TTFields) interfere with biological key properties of glioma cells in vitro

Journal Articles

Abstract 3380: Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

Monica Burgett, Justin Lathia, Patrick Roth, Amy Nowacki, Elena Pugacheva, Ping Huang, Amit Vasanji, Li Meizhang, Tatiana Byzova, Tom Mikkelsen, Shideng Bao, Jeremy Rich, Michael Weller, Candece Gladson

Cancer Res (2016) 76 (14_Supplement): 3380.

https://doi.org/10.1158/1538-7445.AM2016-3380

Published: 15 July 2016

View articletitled, Abstract 3380: Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

Journal Articles

Abstract 4178: L1CAM and integrin αvβ3 mediate direct cell contact between cancer stem cells and endothelial cells: Promotion of endothelial cell migration and survival

Monica E. Burgett, Justin D. Lathia, Patrick Roth, Amy S. Nowacki, Ping Huang, Amit Vasanji, Meizhang Li, Tatiana Byzova, Tom Mikkelsen, Shideng Bao, Jeremy Rich, Michael Weller, Candece L. Gladson

Cancer Res (2015) 75 (15_Supplement): 4178.

https://doi.org/10.1158/1538-7445.AM2015-4178

Published: 01 August 2015

View articletitled, Abstract 4178: L1CAM and integrin αvβ3 mediate direct cell contact between cancer stem cells and endothelial cells: Promotion of endothelial cell migration and survival

Journal Articles

Abstract 203: Inhibiting invasion and stemness in glioblastoma by thymosin beta 4 gene silencing: a new therapeutic target

Hans-Georg Wirsching, Shanmugarajan Krishnan, Ana-Maria Florea, Karl Frei, Niklaus Krayenbühl, Kathy Hasenbach, Guido Reifenberger, Michael Weller, Ghazaleh Tabatabai

Cancer Res (2014) 74 (19_Supplement): 203.

https://doi.org/10.1158/1538-7445.AM2014-203

Published: 01 October 2014

View articletitled, Abstract 203: Inhibiting invasion and stemness in glioblastoma by thymosin beta 4 gene silencing: a new therapeutic target

Journal Articles

Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker.

Benedikt Wiestler, David Capper, Tim Holland-Letz, Andreas von Deimling, Stefan M. Pfister, Michael Platten, Michael Weller, Wolfgang Wick

Cancer Res (2013) 73 (8_Supplement): LB-80.

https://doi.org/10.1158/1538-7445.AM2013-LB-80

Published: 15 April 2013

View articletitled, Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker.

Journal Articles

Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma

Jonas Blaes, Markus Weiler, Felix Sahm, Philipp-Niclas Pfenning, Stefan Pusch, Manfred Jugold, Tore Kempf, Uwe Warnken, Michael Weller, Martina Schnölzer, Christian Hartmann, Andreas von Deimling, Wolfgang Wick

Cancer Res (2012) 72 (8_Supplement): 4736.

https://doi.org/10.1158/1538-7445.AM2012-4736

Published: 15 April 2012

View articletitled, Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma

Journal Articles

Malignant Glioma Cells Counteract Antitumor Immune Responses through Expression of Lectin-Like Transcript-1

Patrick Roth, Michel Mittelbronn, Wolfgang Wick, Richard Meyermann, Marcos Tatagiba, Michael Weller

Cancer Res (2007) 67 (8): 3540–3544.

https://doi.org/10.1158/0008-5472.CAN-06-4783

Published: 17 April 2007

View articletitled, Malignant Glioma Cells Counteract Antitumor Immune Responses through Expression of Lectin-Like Transcript-1

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Abstract 3197: Macrophage-ferritin-drug conjugates: a novel approach to overcome glioblastoma drug resistance and induce long-term tumor immunity

Abstract 4781: Generation and in vivo characterization of a novel antibody targeting Prostatic Acid Phosphatase (ACP-3)

Abstract CT230: Exploratory analyses of MGMT promoter methylation and PD-L1 expression from newly diagnosed glioblastoma patients in CheckMate 548 study suggest refinement in thresholds for predicting response to standard of care and nivolumab treatments

The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen

Abstract CT062: GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

Abstract 1991: Characterization of the exome, transcriptome, and immunopeptidome to map alterations in primary and recurrent glioblastoma

Abstract 1375: The intra-tumoral spatial heterogeneity of T-cell antigens in glioblastoma: An integrated multi-omics approach

Abstract 5325: Image-based functional precision medicine for repurposing neuroactive drugs in glioblastoma

Abstract 2168: Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

Abstract LB-055: Novel therapeutic option targeting the tumor cell lysosomes

Abstract 4886: Patients with EGFR amplification but without EGFRvIII expression have improved benefit compared to those with EGFRvIII expression in samples of the INTELLANCE2/EORTC1410 randomized phase II trial

Abstract 4: Antitumor activity of DLX1008, a single chain antibody fragment binding to VEGF-A, in in vivo preclinical models of Kaposi sarcoma and glioblastoma

NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma

Abstract 1504: Tumor-treating fields (TTFields) interfere with biological key properties of glioma cells in vitro

Abstract 3380: Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

Abstract 4178: L1CAM and integrin αvβ3 mediate direct cell contact between cancer stem cells and endothelial cells: Promotion of endothelial cell migration and survival

Abstract 203: Inhibiting invasion and stemness in glioblastoma by thymosin beta 4 gene silencing: a new therapeutic target

Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker.

Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma

Malignant Glioma Cells Counteract Antitumor Immune Responses through Expression of Lectin-Like Transcript-1

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