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Journal Articles

Abstract 771: Multi-omics profiling can predict for relapse and response to brexucabtagene autoleucel CAR T-cell therapy in patients with mantle cell lymphoma

Vivian Changying Jiang, Dapeng Hao, Preetesh Jain, Yijing Li, Qingsong Cai, Yang Liu, Yuxuan Che, Jovanny Vargas, Yixin Yao, Lei Nie, Enyu Dai, Guangchun Han, Ruiping Wang, Kunal Rai, Andrew Futreal, Christopher Flowers, Linghua Wang, Michael Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 771.
DOI: https://doi.org/10.1158/1538-7445.AM2022-771
Published: 15 June 2022
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Journal Articles

Abstract CT127: Trial in progress: A phase II, open-label, multicenter study of capivasertib, a potent, oral pan-AKT inhibitor in patients with relapsed or refractory B-cell non-hodgkin lymphoma (CAPITAL)

Michael Wang, Ho-Jin Shin, Alex F. Herrera, Moshe Levy, Wong Seog Kim, Tae Min Kim, Jin Seok Kim, Dok Hyun Yoon, Vincent Ribrag, Miguel Canales, John Radford, Dima El-Sharkawi, Brandy Hemmer, Richa Manwani, Veerendra Munugalavadla, Robert Chen, Andrew Mortlock, Alessandra Forcina, Franck Morschhauser
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT127.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT127
Published: 15 June 2022
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Journal Articles

Abstract 3955: Targeting transcription elongation via CDK9 in mantle cell lymphoma patients with dual resistance to BTK inhibition and CAR T therapy

Vivian Changying Jiang, Lingzhi Li, Alexa Jordan, Yu Xue, Fangfang Yan, Joseph McIntosh, Yang Liu, Yuxuan Che, Yijing Li, Qingsong Cai, Angela Leeming, Lukas Simon, Zhongming Zhao, Jia Zhou, Michael Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3955.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3955
Published: 15 June 2022
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Journal Articles

Abstract 120: Compartmentalized functions of epidermal growth factor receptor (EGFR) in tumorigenesis and malignant phenotypes

Lei Nie, Junwei Hou, Yu-Yi Chu, Ying-Nai Wnag, Li-Chuan Chan, Longfei Huo, Paul Chiao, Shao-Chun Wang, Mien-Chie Hung, Michael Wang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 120.
DOI: https://doi.org/10.1158/1538-7445.AM2021-120
Published: 01 July 2021
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Journal Articles

Abstract 1112: Exploiting oncogene-conferred glutamine addiction as a therapeutic vulnerability in resistant mantle cell lymphoma

Lingzhi Li, Changying Jiang, Lucy J. Navsaria, Yang Liu, Joseph M. McIntosh, Michael Wang, Yinxin Yao
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1112.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1112
Published: 01 July 2021
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Journal Articles

Abstract 5683: Single-cell RNA-seq reveals heterogeneity, clonal evolution and strategies to overcome ibrutinib-venetoclax dual resistance in mantle cell lymphoma

Changying Jiang, Shaojun Zhang, Yuanxin Wang, Rongjia Zhang, Yang Liu, Joseph McIntosh, Guangchun Han, Ruiping Wang, David Santos, Maria Badillo, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Lee, Raphael Steiner, Jorge Romaguera, Preetesh Jain, Krystle Nomie, Andy Futreal, Linghua Wang, Michael Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5683.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5683
Published: 15 August 2020
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Journal Articles

Abstract 652: Exploiting PRMT5, a metabolic and epigenetic regulator, as a novel therapeutic target in mantle cell lymphoma

Yixin Yao, Lingzhi Li, Liang Zhang, Shaojun Zhang, Hui Guo, Hui Zhang, Maria Badillo, Zhihong Chen, Kimberly Hartig, Preetesh Jain, Krystle Nomie, Linghua Wang, Michael Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 652.
DOI: https://doi.org/10.1158/1538-7445.AM2020-652
Published: 15 August 2020
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Journal Articles

Abstract 3702: Establishment and characterization of a novel MYC/BCL2 double-hit high-grade B-cell lymphoma cell line HLA-3

Hui Guo, Hui Zhang, Krystle Nomie, Liang Zhang, Kelley P. Murfin, Michael Wang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3702.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3702
Published: 01 July 2019
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Journal Articles

Abstract 3459: Dual targeting of BTK and PLK1 causes lethal synergistic effects in mantle cell lymphoma

Changying Jiang, Shengjian Huang, Yang Liu, Krystle Nomie, Leo Zhang, Michael Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3459.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3459
Published: 01 July 2018
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Journal Articles

Abstract 1981: Pan-cancer pathways gene expression profiling in mantle cell lymphoma reveals upregulation of DNA damage repair genes in ibrutinib-resistant tumor

Makhdum Ahmed, Elizabeth Lorence, Hui Guo, Shengjian Huang, Victoria Zhang, Hui Zhang, Liang Zhang, Krystle Nomie, Michael Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1981.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1981
Published: 01 July 2018
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Journal Articles

Abstract 4099: Targeting the paracaspase MALT1: A potential therapy to overcome ibrutinib resistance in relapsed/refractory MCL patients

Changying Jiang, Shengjian Huang, Xin Lin, Michael Wang, Liang Zhang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4099.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4099
Published: 01 July 2017
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Journal Articles

Abstract 4391: Overcoming primary ibrutinib resistance in mantle cell lymphoma

Leo Zhang, Lan Pham, Hui Zhang, Jingmeng Xie, Wenjing Tao, Taylor Bell, Zhihong Chen, Krystle Nomie, Bingliang Fang, Michael Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4391.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4391
Published: 15 July 2016
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Journal Articles

Abstract 2432: The bruton's tyrosine kinase inhibitor ibrutinib synergized with the proteasome inhibitor carfilzomib and overcame immunoproteasome-mediated carfilzomib resistance in mantle cell lymphoma .

Zhishuo Ou, Liang Zhang, Kate Newberry, Luhong Sun, Kirk J. Christopher, Alex Rollo, Archito Tamayo, John Lee, Richard J. Ford, Michael Wang, Lan V. Pham
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2432.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2432
Published: 15 April 2013
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Journal Articles

Abstract 3389: Nuclear accumulation of c-Rel transcription factor is correlated with the proteasome inhibitor resistance in mantle cell lymphoma.

Marzenna Blonska, Deng Pan, Zhishuo Ou, Liang Zhang, Xin Lin, Michael Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3389.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3389
Published: 15 April 2013
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Journal Articles

Abstract 3444: Novel SINE CRM1 antagonists for non-small cell lung cancer (NSCLC) in vitro and in vivo.

Xiaohong Han, Shuai Wang, Yuankai Shi, Michael Wang, Liang Zhang, Bingliang Fang, Dilara McCauley, Michael Kauffman, Sharon Shacham
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3444.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3444
Published: 15 April 2013
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Journal Articles

Abstract 4310: Prospective isolation of clongenic mantle cell lymphoma initiating cells

Zheng Chen, Paul Ayala, Michael Wang, Luis Fayad, Ruth L. Katz, Jorge Romaguera, Nancy Caraway, Sattva S. Neelapu, Larry W. Kwak, Paul Simmons, McCarty Nami
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4310.
DOI: https://doi.org/10.1158/1538-7445.AM10-4310
Published: 15 April 2010
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Journal Articles

Abstract 2177: Long-term storage in TRIzol has little effect on microarray-based gene expression profiling in primary myeloma or acute myeloid leukemia cells

Michael Wang, Zhi-Qiang Wang, Luhong Sun, Wencai Ma, David Graber, Jairo Matthews, Richard Champlin, Qing Yi, Robert Z. Orlowski, Larry Kwak, Donna M. Weber, Sheeba K. Thomas, Jatin Shah, Steven Kornblau, Richard E. Davis
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2177.
DOI: https://doi.org/10.1158/1538-7445.AM10-2177
Published: 15 April 2010
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Journal Articles

Abstract 2629: Carfilzomib, an irreversible proteasome inhibitor, induces caspase-dependent apoptosis and inhibits the growth of mantle cell lymphoma in vitro and in tumor-bearing SCID mice

Liang Zhang, Jianfei Qian, Jing Yang, Monette Aujay, Susan Demo, Qing Yi, Michael Wang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2629.
DOI: https://doi.org/10.1158/1538-7445.AM10-2629
Published: 15 April 2010
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Journal Articles

Abstract #LB-166: Promoter CGI methylation of reprogramming factors in aggressive B-cell lymphomas

Deiter Duff, Srilatha Nalluri, Michael Wang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-166.
Published: 01 May 2009
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Journal Articles

Bortezomib is synergistic with rituximab and cyclophosphamide in inducing apoptosis of mantle cell lymphoma cells in vitro and in vivo

Michael Wang, Xiaohong Han, Liang Zhang, Luhong Sun, Jing Yang, Jianfei Qian, Larry Kwak, Jorge Romaguera, Yuankai Shi, Qing Yi
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4023.
Published: 01 May 2008
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