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Michael VanSaun
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Journal Articles

Abstract 2967: The mammalian 8-oxo-dGTPase, MTH1, as a novel targetable vulnerability in pancreatic ductal adenocarcinoma

Beatriz Mateo-Victoriano, Ling Zhang, Jaya Samaranayake, Z McGaughey, Cassie Due, Clara Troccoli, Michael G. Mohsen, Nagaraj Nagathihalli, Oliver G. McDonald, Michael VanSaun, Eric T. Kool, Priyamvada Rai
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2967.
https://doi.org/10.1158/1538-7445.AM2024-2967
Published: 22 March 2024
View article titled, Abstract 2967: The mammalian 8-oxo-dGTPase, MTH1, as a novel targetable vulnerability in pancreatic ductal adenocarcinoma
Journal Articles

Abstract B091: The mammalian 8-oxodGTPase, MTH1, as a novel targetable vulnerability in pancreatic ductal adenocarcinoma

Beatriz Mateo-Victoriano, Ling Zhang, Govindi J. Samaranayake, Vanessa Mcgaughey, Cassie Due, Clara Troccoli, Michael G. Mohsen, Nagaraj S. Nagathihalli, Oliver G. McDonald, Michael VanSaun, Eric T. Kool, Priyamvada Rai
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B091.
https://doi.org/10.1158/1538-7445.PANCA2023-B091
Published: 16 January 2024
View article titled, Abstract B091: The mammalian 8-oxodGTPase, MTH1, as a novel targetable vulnerability in pancreatic ductal adenocarcinoma
Journal Articles

Abstract A034: Thermoregulation alters adipose influence of pancreatic cancer growth

Austin Eades, Bailey Bye, R. McKinnon Walsh, Michael VanSaun
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A034.
https://doi.org/10.1158/1538-7445.PANCA2023-A034
Published: 16 January 2024
View article titled, Abstract A034: Thermoregulation alters adipose influence of pancreatic cancer growth
Journal Articles

Abstract 1585: Targeting acid ceramidase-1 to inhibit sphingolipid metabolism and tumor growth in pancreatic ductal carcinoma

Krishan G. Jain, Hindole Ghosh, Sangita Bhattacharyya, Anup Kasi, Ameer Hamza, Scott J. Weir, Michael VanSaun, Stefan Bossmann, Shrikant Anant, Bernhard Biersack, Prasad R. Dandawate
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1585.
https://doi.org/10.1158/1538-7445.AM2023-1585
Published: 04 April 2023
View article titled, Abstract 1585: Targeting acid ceramidase-1 to inhibit sphingolipid metabolism and tumor growth in pancreatic ductal carcinoma
Journal Articles

Abstract 4790: Oxidation in the nucleotide pool as a novel targetable vulnerability in pancreatic ductal adenocarcinoma

Beatriz Mateo-Victoriano, Ling Zhang, Govindi J. Samaranayake, Cassie Due, Clara Troccoli, Julia Zaias, Nagaraj Nagathihalli, Michael VanSaun, Michael G. Mohsen, Eric T. Kool, Priyamvada Rai
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4790.
https://doi.org/10.1158/1538-7445.AM2023-4790
Published: 04 April 2023
View article titled, Abstract 4790: Oxidation in the nucleotide pool as a novel targetable vulnerability in pancreatic ductal adenocarcinoma
Journal Articles

Abstract C081: Opposing effects of white and brown adipose tissue on PDAC growth

Austin Eades, Michael VanSaun, McKinnon R. Walsh, Bailey Bye, Appolinaire Olou, Joe Ambrose, Jarrid Jack
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C081.
https://doi.org/10.1158/1538-7445.PANCA22-C081
Published: 15 November 2022
View article titled, Abstract C081: Opposing effects of white and brown adipose tissue on PDAC growth
Journal Articles

Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer

Supriya Srinivasan, Tulasigeri Totiger, Chanjuan Shi, Jason Castellanos, Purushottam Lamichhane, Austin R. Dosch, Fanuel Messaggio, Nilesh Kashikar, Kumaraswamy Honnenahally, Yuguang Ban, Nipun B. Merchant, Michael VanSaun, Nagaraj S. Nagathihalli
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (21): 6146–6158.
https://doi.org/10.1158/0008-5472.CAN-18-0579
Published: 01 November 2018
View article titled, Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer
Open the PDF for Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1249: Animal model in the prevention of alcoholic pancreatitis

Supriya Srinivasan, Tulasigeri Totiger, Michael VanSaun, Fanuel Messaggio, Chanjuan Shi, Austin Dosch, Eric Nestler, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1249.
https://doi.org/10.1158/1538-7445.AM2018-1249
Published: 01 July 2018
View article titled, Abstract 1249: Animal model in the prevention of alcoholic pancreatitis
Journal Articles

Abstract 5042: CREB transgenic mice to study alcohol-associated pancreatic carcinogenesis

Tulasigeri Totiger, Supriya Srinivasan, Michael VanSaun, Chandrashekhar Joshi, Chanjuan Shi, Xizi Dai, Rajinder Dawra, Alexander Gaidarski, Eric Nestler, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5042.
https://doi.org/10.1158/1538-7445.AM2018-5042
Published: 01 July 2018
View article titled, Abstract 5042: CREB transgenic mice to study alcohol-associated pancreatic carcinogenesis
Journal Articles

Abstract 5259: Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling

Supriya Srinivasan, Venkatakrishna Jala, Kumar Honnenahally, Jason Castellanos, Praveen Kumar Vermula, Michael VanSaun, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5259.
https://doi.org/10.1158/1538-7445.AM2017-5259
Published: 01 July 2017
View article titled, Abstract 5259: Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling
Journal Articles

Abstract B71: Resistance to MEK inhibition in pancreatic cancer is associated with amphiregulin mediated EGFR-STAT3 activation

Nagaraj Nagathihalli, Jason Castellanos, Chanjuan Shi, Casey Roberts, Michael VanSaun, Nipun Merchant
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B71.
https://doi.org/10.1158/1538-7445.PANCA16-B71
Published: 14 December 2016
View article titled, Abstract B71: Resistance to MEK inhibition in pancreatic cancer is associated with amphiregulin mediated EGFR-STAT3 activation
Journal Articles

Abstract B78: RAD51 sensitizes pancreatic cancer cells to AKT inhibition

Surpiya Srinivasan, Chanjuan Shi, Casey Roberts, Xizi Dai, Fanuel Messaggio, Krisztina Kovacs, Michael VanSaun, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B78.
https://doi.org/10.1158/1538-7445.PANCA16-B78
Published: 14 December 2016
View article titled, Abstract B78: RAD51 sensitizes pancreatic cancer cells to AKT inhibition
Journal Articles

Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer

Jason Castellanos, Supriya Srinivasan, Kumar Honnenahally, Chanjuan Shi, Michael VanSaun, David Robbins, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2618.
https://doi.org/10.1158/1538-7445.AM2016-2618
Published: 15 July 2016
View article titled, Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer
Journal Articles

Abstract 3959: MMP13 contributes to metastatic tumor growth in the steatotic liver microenvironment.

Alisha M. Mendonsa, Michael VanSaun, David L. Gorden
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3959.
https://doi.org/10.1158/1538-7445.AM2013-3959
Published: 15 April 2013
View article titled, Abstract 3959: MMP13 contributes to metastatic tumor growth in the steatotic liver microenvironment.