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Journal Articles

Abstract 2763: A specific ribomethylome pattern in lung cancer is associated with increased risk of metastasis

Cancer Res (2024) 84 (6_Supplement): 2763.

https://doi.org/10.1158/1538-7445.AM2024-2763

Published: 22 March 2024

View article titled, Abstract 2763: A specific ribomethylome pattern in lung cancer is associated with increased risk of metastasis

Journal Articles

Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients

Cancer Res (2022) 82 (12_Supplement): 3374.

https://doi.org/10.1158/1538-7445.AM2022-3374

Published: 15 June 2022

View article titled, Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients

Journal Articles

Abstract CT255: Canakinumab as adjuvant therapy in patients with completely resected non-small cell lung cancer: CANOPY-A trial

Alexander Spira, Andrea Ardizzoni, Fabrice Barlesi, Byoung Chul Cho, Pedro De Marchi, Yasushi Goto, Dariusz Kowalski, Shun Lu, Luis Paz-Ares, David R. Spigel, Michael Thomas, Sabine Turri, Vanessa Rodrik-Outmezguine, Wen Zhou, Terri Kreisl, James Chih-Hsin Yang, Edward B. Garon

Cancer Res (2021) 81 (13_Supplement): CT255.

https://doi.org/10.1158/1538-7445.AM2021-CT255

Published: 01 July 2021

View article titled, Abstract CT255: Canakinumab as adjuvant therapy in patients with completely resected non-small cell lung cancer: CANOPY-A trial

Journal Articles

Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERa^WT and ERa^MUT breast cancer

Cancer Res (2021) 81 (4_Supplement): PS12-23.

https://doi.org/10.1158/1538-7445.SABCS20-PS12-23

Published: 15 February 2021

View article titled, Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERa<sup>WT</sup> and ERa<sup>MUT</sup> breast cancer

Journal Articles

Abstract 728: Early assessment of treatment effect in small cell lung cancer (SCLC) via ctDNA analysis

John Jiang, Christine Ju, Corinna Woestmann, Aarthi Balasubramanyam, Liu Xi, Stephanie J. Yaung, Sandeep Gattam, Bernd Hinzmann, Michael Thomas, Felix Lasitschka, Michael Meister, Marc Schneider, Felix Herth, Thomas Muley, Birgit Wehnl, John Palma

Cancer Res (2020) 80 (16_Supplement): 728.

https://doi.org/10.1158/1538-7445.AM2020-728

Published: 15 August 2020

View article titled, Abstract 728: Early assessment of treatment effect in small cell lung cancer (SCLC) via ctDNA analysis

Journal Articles

Abstract 1571: Inter- and intra- tumorheterogeneity of the microenvironment in pulmonary adenocarcinoma

Cancer Res (2020) 80 (16_Supplement): 1571.

https://doi.org/10.1158/1538-7445.AM2020-1571

Published: 15 August 2020

View article titled, Abstract 1571: Inter- and intra- tumorheterogeneity of the microenvironment in pulmonary adenocarcinoma

Journal Articles

Abstract 3093: Quantifying the confounders of panel-based tumor mutational burden (TMB) measurement

Jan Budczies, Daniel Kazdal, Michael Allgäuer, Petros Christopoulos, Eugen Rempel, Nicole Pfarr, Wilko Weichert, Stefan Fröhling, Michael Thomas, Solange Peters, Volker Endris, Peter Schirmacher, Albrecht Stenzinger

Cancer Res (2020) 80 (16_Supplement): 3093.

https://doi.org/10.1158/1538-7445.AM2020-3093

Published: 15 August 2020

View article titled, Abstract 3093: Quantifying the confounders of panel-based tumor mutational burden (TMB) measurement

Journal Articles

Abstract CT286: CANOPY program clinical trials: Canakinumab (Cana) in patients (pts) with non-small cell lung cancer (NSCLC)

Cancer Res (2020) 80 (16_Supplement): CT286.

https://doi.org/10.1158/1538-7445.AM2020-CT286

Published: 15 August 2020

View article titled, Abstract CT286: CANOPY program clinical trials: Canakinumab (Cana) in patients (pts) with non-small cell lung cancer (NSCLC)

Journal Articles

Abstract CT287: CANOPY-A: A phase III, multicenter, randomized trial evaluating canakinumab versus placebo as adjuvant therapy in patients with completely resected non-small cell lung cancer (NSCLC)

Edward B. Garon, Andrea Ardizzoni, Fabrice Barlesi, Byoung Chul Cho, Pedro De Marchi, Yasushi Goto, Dariusz Kowalski, Shun Lu, Luis Paz-Ares, David R. Spigel, Alexander Spira, Michael Thomas, Mimi Leung, Jason Baum, Zewen Zhu, Bijoyesh Mookerjee, James Chih-Hsin Yang

Cancer Res (2020) 80 (16_Supplement): CT287.

https://doi.org/10.1158/1538-7445.AM2020-CT287

Published: 15 August 2020

View article titled, Abstract CT287: CANOPY-A: A phase III, multicenter, randomized trial evaluating canakinumab versus placebo as adjuvant therapy in patients with completely resected non-small cell lung cancer (NSCLC)

Journal Articles

Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer

Cancer Res (2017) 77 (13_Supplement): DDT01-04.

https://doi.org/10.1158/1538-7445.AM2017-DDT01-04

Published: 01 July 2017

View article titled, Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer

Journal Articles

Abstract 1185: H3B-8800, a novel orally available SF3b modulator, shows preclinical efficacy across spliceosome mutant cancers

Cancer Res (2017) 77 (13_Supplement): 1185.

https://doi.org/10.1158/1538-7445.AM2017-1185

Published: 01 July 2017

View article titled, Abstract 1185: H3B-8800, a novel orally available SF3b modulator, shows preclinical efficacy across spliceosome mutant cancers

Journal Articles

Abstract 2932: SF3B1 mutations induce aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

Cancer Res (2014) 74 (19_Supplement): 2932.

https://doi.org/10.1158/1538-7445.AM2014-2932

Published: 01 October 2014

View article titled, Abstract 2932: SF3B1 mutations induce aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

Journal Articles

Abstract LB-6: Non-covalent assembly of meso-tetra-4-pyridyl porphine with single-stranded DNA to form nano-sized complexes with pH-dependent DNA release and anti-tumor activity.

William H. Gmeiner, Supratim Ghosh, Kamil B. Ucer, Richard T. Williams, Ralph D'Agostino, Ken Grant, Joseph Sirintrapun, Michael Thomas, Roy Hantgan, Manish Bharadwaj

Cancer Res (2013) 73 (8_Supplement): LB-6.

https://doi.org/10.1158/1538-7445.AM2013-LB-6

Published: 15 April 2013

View article titled, Abstract LB-6: Non-covalent assembly of meso-tetra-4-pyridyl porphine with single-stranded DNA to form nano-sized complexes with pH-dependent DNA release and anti-tumor activity.

Journal Articles

Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924

Hernan Carol, Richard B. Lock, John M. Maris, Stephen T. Keir, Richard Gorlick, E. Anders Kolb, Min H. Kang, C Patrick Reynolds, Christopher L. Morton, Peter G. Smith, Michael Thomas, Alice McDonald, Peter J. Houghton, Malcolm A. Smith

Cancer Res (2011) 71 (8_Supplement): 740.

https://doi.org/10.1158/1538-7445.AM2011-740

Published: 15 April 2011

View article titled, Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924

Journal Articles

Abstract #2040: Cyclosporin A sensitizes cancer cells to death receptor-mediated apoptosis

Ranxin Shi, Michael Thomas, John Reed

Cancer Res (2009) 69 (9_Supplement): 2040.

Published: 01 May 2009

View article titled, Abstract #2040: Cyclosporin A sensitizes cancer cells to death receptor-mediated apoptosis

Journal Articles

Inhibition of FLIP sensitizes resistant cells to anoikis and decreases their metastatic potential.

Craig Simpson, Imtiaz Mawji, Rose Hurren, Marcela Gronda, Moyo Williams, Jorge Filmus, James Jonkman, Ralph Da Costa, Brian Wilson, Michael Thomas, John Reed, Gennadi Glinsky, Aaron Schimmer

Cancer Res (2007) 67 (9_Supplement): 1603.

Published: 01 May 2007

View article titled, Inhibition of FLIP sensitizes resistant cells to anoikis and decreases their metastatic potential.

Journal Articles

Daxx Represses Expression of a Subset of Antiapoptotic Genes Regulated by Nuclear Factor-κB

Rhonda Croxton, Lorena A. Puto, Ian de Belle, Michael Thomas, Seiji Torii, Farid Hanaii, Michael Cuddy, John C. Reed

Cancer Res (2006) 66 (18): 9026–9035.

https://doi.org/10.1158/0008-5472.CAN-06-1047

Published: 18 September 2006

View article titled, Daxx Represses Expression of a Subset of Antiapoptotic Genes Regulated by Nuclear Factor-κB

Journal Articles

Identification of Metastasis-Associated Receptor Tyrosine Kinases in Non–Small Cell Lung Cancer

Carsten Müller-Tidow, Sven Diederichs, Etmar Bulk, Thorsten Pohle, Björn Steffen, Joachim Schwäble, Sylvia Plewka, Michael Thomas, Ralf Metzger, Paul M. Schneider, Christian H. Brandts, Wolfgang E. Berdel, Hubert Serve

Cancer Res (2005) 65 (5): 1778–1782.

https://doi.org/10.1158/0008-5472.CAN-04-3388

Published: 07 March 2005

View article titled, Identification of Metastasis-Associated Receptor Tyrosine Kinases in Non–Small Cell Lung Cancer

Journal Articles

S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer

Sven Diederichs, Etmar Bulk, Björn Steffen, Ping Ji, Lara Tickenbrock, Kerstin Lang, Kurt S. Zänker, Ralf Metzger, Paul M. Schneider, Volker Gerke, Michael Thomas, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow

Cancer Res (2004) 64 (16): 5564–5569.

https://doi.org/10.1158/0008-5472.CAN-04-2004

Published: 16 August 2004

View article titled, S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Induction of PDGF-B expression in HUVECs by growth factors and conditioned medium derived from lung cancer cells.

Niels Reinmuth, Sonja Rensinghoff, Heike Hintelmann, Guido Bisping, Frank Hilberg, Gerald J. Roth, Wolfgang E. Berdel, Michael Thomas, Rolf M. Mesters

Cancer Res (2004) 64 (7_Supplement): 829–830.

Published: 01 April 2004

View article titled, Induction of PDGF-B expression in HUVECs by growth factors and conditioned medium derived from lung cancer cells.

NARROW

Abstract 2763: A specific ribomethylome pattern in lung cancer is associated with increased risk of metastasis

Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients

Abstract CT255: Canakinumab as adjuvant therapy in patients with completely resected non-small cell lung cancer: CANOPY-A trial

Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERa^WT and ERa^MUT breast cancer

Abstract 728: Early assessment of treatment effect in small cell lung cancer (SCLC) via ctDNA analysis

Abstract 1571: Inter- and intra- tumorheterogeneity of the microenvironment in pulmonary adenocarcinoma

Abstract 3093: Quantifying the confounders of panel-based tumor mutational burden (TMB) measurement

Abstract CT286: CANOPY program clinical trials: Canakinumab (Cana) in patients (pts) with non-small cell lung cancer (NSCLC)

Abstract CT287: CANOPY-A: A phase III, multicenter, randomized trial evaluating canakinumab versus placebo as adjuvant therapy in patients with completely resected non-small cell lung cancer (NSCLC)

Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer

Abstract 1185: H3B-8800, a novel orally available SF3b modulator, shows preclinical efficacy across spliceosome mutant cancers

Abstract 2932: SF3B1 mutations induce aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

Abstract LB-6: Non-covalent assembly of meso-tetra-4-pyridyl porphine with single-stranded DNA to form nano-sized complexes with pH-dependent DNA release and anti-tumor activity.

Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924

Abstract #2040: Cyclosporin A sensitizes cancer cells to death receptor-mediated apoptosis

Inhibition of FLIP sensitizes resistant cells to anoikis and decreases their metastatic potential.

Daxx Represses Expression of a Subset of Antiapoptotic Genes Regulated by Nuclear Factor-κB

Identification of Metastasis-Associated Receptor Tyrosine Kinases in Non–Small Cell Lung Cancer

S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer

Induction of PDGF-B expression in HUVECs by growth factors and conditioned medium derived from lung cancer cells.

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