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Journal Articles

Correction: Antibody–Peptide Epitope Conjugates for Personalized Cancer Therapy

Songfa Zhang, Chuan Yan, David G. Millar, Qiqi Yang, James M. Heather, Adam Langenbucher, Laura T. Morton, Sean Sepulveda, Eric Alpert, Lauren R. Whelton, Dominique T. Zarrella, Mei Guo, Eleanor Minogue, Michael S. Lawrence, Bo R. Rueda, David R. Spriggs, Weiguo Lu, David M. Langenau, Mark Cobbold
Journal: Cancer Research
Cancer Res (2024) 84 (9): 1534.
https://doi.org/10.1158/0008-5472.CAN-24-0718
Published: 02 May 2024
View articletitled, Correction: Antibody–Peptide Epitope Conjugates for Personalized Cancer Therapy
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Journal Articles

Abstract 1648: RB represses cohesin-dependent loop formation and activates E2F-independent transcription

Hanjun Lee, Ioanna-Maria Gkotinakou, Badri Krishnan, Nicholas J. Dyson, Michael S. Lawrence, Ioannis Sanidas
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1648.
https://doi.org/10.1158/1538-7445.AM2024-1648
Published: 22 March 2024
View articletitled, Abstract 1648: RB represses cohesin-dependent loop formation and activates E2F-independent transcription
Journal Articles

Abstract 1420: The non-canonical role of Rb in enhancers and insulators

Hanjun Lee, Ioanna M. Gkotinakou, Ioannis Sanidas, Michael S. Lawrence, Nicholas J. Dyson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1420.
https://doi.org/10.1158/1538-7445.AM2023-1420
Published: 04 April 2023
View articletitled, Abstract 1420: The non-canonical role of Rb in enhancers and insulators
Journal Articles

Abstract IA010: Hypomethylation of immune-related loci contribute to prostate tumorigenesis

Daniel A. Haber, Hongshan Guo, Ben S. Wittner, Joanna A Vuille, Michael S. Lawrence, Chin-Lee Wu, Mehmet Toner, David T. Miyamoto, Shyamala Maheswaran
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_2): IA010.
https://doi.org/10.1158/1538-7445.METASTASIS22-IA010
Published: 15 January 2023
View articletitled, Abstract IA010: Hypomethylation of immune-related loci contribute to prostate tumorigenesis
Journal Articles

Abstract 657: Impact of therapy induced APOBEC3A mutagenesis on tumor evolution in non small cell lung cancer

Hideko Isozaki, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Ramin Sakhtemani, Susanna L. Monroe, Alice T. Shaw, Jessica J. Lin, Lecia V. Sequist, Zofia Piotrowska, Rémi Buisson, Michael S. Lawrence, Aaron N. Hata
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 657.
https://doi.org/10.1158/1538-7445.AM2022-657
Published: 15 June 2022
View articletitled, Abstract 657: Impact of therapy induced APOBEC3A mutagenesis on tumor evolution in non small cell lung cancer
Journal Articles

Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition

Nezihi Murat Karabacak, Yu Zheng, Taronish D. Dubash, Risa Burr, Douglas S. Micalizzi, Ben S. Wittner, Maoxuan Lin, Devon F. Wiley, Valentine Comaills, Erin Emmons, Kira L. Niederhoffer, Uyen Ho, Jacob Ukleja, Dante Che, Hannah Stowe, Linda T. Nieman, Wilhelm Haas, Shannon L. Stott, Michael S. Lawrence, David T. Ting, David T. Miyamoto, Daniel A. Haber, Mehmet Toner, Shyamala Maheswaran
Journal: Cancer Research
Cancer Res (2022) 82 (6): 1084–1097.
https://doi.org/10.1158/0008-5472.CAN-21-2609
Published: 15 March 2022
View articletitled, Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition
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Includes: Supplementary data
Journal Articles

Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy

Songfa Zhang, Chuan Yan, David G. Millar, Qiqi Yang, James M. Heather, Adam Langenbucher, Laura T. Morton, Sean Sepulveda, Eric Alpert, Lauren R. Whelton, Dominique T. Zarrella, Mei Guo, Eleanor Minogue, Michael S. Lawrence, Bo R. Rueda, David R. Spriggs, Weiguo Lu, David M. Langenau, Mark Cobbold
Journal: Cancer Research
Cancer Res (2022) 82 (5): 773–784.
https://doi.org/10.1158/0008-5472.CAN-21-2200
Published: 01 March 2022
View articletitled, Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy
Open the PDF for Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract 39: APOBEC3A drives acquired resistance to targeted therapies in non small cell lung cancer

Hideko Isozaki, Ammal Abbasi, Naveed Nikpour, Adam Langenbucher, Wenjia Su, Marcello Stanzione, Lecia V. Sequist, Rémi Buisson, Michael S. Lawrence, Aaron N. Hata
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 39.
https://doi.org/10.1158/1538-7445.AM2021-39
Published: 01 July 2021
View articletitled, Abstract 39: APOBEC3A drives acquired resistance to targeted therapies in non small cell lung cancer
Journal Articles

Abstract 2473: NR4A1 suppresses cancer replication stress through R-loop-dependent inhibition of immediate early gene transcriptional elongation

Hongshan Guo, Gabriel Golczer, Shyamala Maheswaran, Michael S. Lawrence, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2473.
https://doi.org/10.1158/1538-7445.AM2021-2473
Published: 01 July 2021
View articletitled, Abstract 2473: NR4A1 suppresses cancer replication stress through R-loop-dependent inhibition of immediate early gene transcriptional elongation
Journal Articles

Abstract 4893: Multi-modality sequencing of multiple HPV mediated oropharyngeal squamous cell carcinomas from single patients reveals synchrony in viral genomes yet discordant mutational profiles and signatures

Daniel L. Faden, Adam Langenbucher, Krystle Kuhs, James S. Lewis, Michael S. Lawrence, Lisa Mirabello, Robert L. Ferris
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4893.
https://doi.org/10.1158/1538-7445.AM2020-4893
Published: 15 August 2020
View articletitled, Abstract 4893: Multi-modality sequencing of multiple HPV mediated oropharyngeal squamous cell carcinomas from single patients reveals synchrony in viral genomes yet discordant mutational profiles and signatures
Journal Articles

APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition

Rémi Buisson, Michael S. Lawrence, Cyril H. Benes, Lee Zou
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4567–4578.
https://doi.org/10.1158/0008-5472.CAN-16-3389
Published: 31 August 2017
View articletitled, APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition
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Includes: Supplementary data
Journal Articles

Abstract LB-280: The landscape of somatic microsatellite indels across cancer: detection and identification of driver events

Yosef E. Maruvka, Kent W. Mouw, Rosa Karlic, Rasanna Parasuraman, Atanas Kamburov, Paz Polak, Nicholas J. Haradhvala, Julian M. Hess, Esther Rheinbay, Yehuda Brody, Lior Z. Braunstein, Alan D’Andrea, Michael S. Lawrence, Adam Bass, Andre Bernards, Franziska Michor, Gad Getz
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-280.
https://doi.org/10.1158/1538-7445.AM2017-LB-280
Published: 01 July 2017
View articletitled, Abstract LB-280: The landscape of somatic microsatellite indels across cancer: detection and identification of driver events
Journal Articles

Abstract 5567: A scalable and integrated computational and experimental workflow to identify new driver genes in cancer genome data

Heiko Horn, Michael S. Lawrence, Candace R. Chouinard, Yashaswi Shrestha, Jessica Xin Hu, Elizabeth Worstell, Emily Shea, Nina Ilic, Eejung Kim, Atanas Kamburov, Alireza Kashani, William C. Hahn, Joshua D. Campbell, Jesse S. Boehm, Gad Getz, Kasper Lage
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5567.
https://doi.org/10.1158/1538-7445.AM2017-5567
Published: 01 July 2017
View articletitled, Abstract 5567: A scalable and integrated computational and experimental workflow to identify new driver genes in cancer genome data
Journal Articles

Abstract 1093: Sensitive detection of somatic mutations in class I HLA genes reveals enrichment for functional events in cancer

Sachet A. Shukla, Mohini Rajasagi, Philip Dixon, Grace Tiao, Michael S. Lawrence, Carrie Sougnez, Vladimir Brusic, Kristian Cibulskis, Adam Kiezun, Catherine J. Wu, Gad Getz
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1093.
https://doi.org/10.1158/1538-7445.AM2015-1093
Published: 01 August 2015
View articletitled, Abstract 1093: Sensitive detection of somatic mutations in class I HLA genes reveals enrichment for functional events in cancer
Journal Articles

Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer

Akinyemi I. Ojesina, Bradley Murray, Line Bjorge, Kathrine Woie, Camilla Krakstad, Lee Lichtenstein, Chandra Sekhar Pedamallu, Amaro Taylor-Weiner, Samuel S. Freeman, Andrew D. Cherniack, Michael S. Lawrence, Kristian Cibulskis, Scott L. Carter, Heather Walline, Thomas E. Carey, Olav K. Vintermyr, Bjorn Bertelsen, Christopher P. Crum, Gad Getz, Matthew Meyerson, Helga B. Salvesen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4692.
https://doi.org/10.1158/1538-7445.AM2014-4692
Published: 01 October 2014
View articletitled, Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer
Journal Articles

Abstract IA13: Recurrent SPOP mutations define a distinct molecular subclass of prostate cancer

Christopher E. Barbieri, Sylvan C. Baca, Michael S. Lawrence, Gad Getz, Mark A. Rubin, Levi A. Garraway, On the behalf of the Broad Institute and Weill Cornell Medical College Prostate Cancer Sequencing Group
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): IA13.
https://doi.org/10.1158/1538-7445.PRCA2012-IA13
Published: 09 May 2013
View articletitled, Abstract IA13: Recurrent SPOP mutations define a distinct molecular subclass of prostate cancer
Journal Articles

Abstract 4601: Punctuated evolution of prostate cancer genomes.

Sylvan C. Baca, Davide Prandi, Michael S. Lawrence, Juan Miguel Mosquera, Alessandro Romanel, Yotam Drier, Kyung Park, Naoki Kitabayashi, Theresa Y. MacDonald, Eliezer Van Allen, Gregory V. Kryukov, Jean-Philippe Theurillat, T. David Soong, Elizabeth Nickerson, Daniel Auclair, Ashutosh Tewari, Himisha Beltran, Robert C. Onofrio, Gunther Boysen, Candace Guiducci, Christopher E. Barbieri, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter, Douglas Voet, Gordon Saksena, Michelle R. Cipicchio, Kristin Ardlie, Philip W. Kantoff, Michael F. Berger, Stacey B. Gabriel, Todd R. Golub, Matthew Meyerson, Eric S. Lander, Olivier Elemento, Gad Getz, Francesca Demichelis, Mark A. Rubin, Levi A. Garraway
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4601.
https://doi.org/10.1158/1538-7445.AM2013-4601
Published: 15 April 2013
View articletitled, Abstract 4601: Punctuated evolution of prostate cancer genomes.
Journal Articles

Abstract 4600: Analysis of clonal evolution in cancer using whole exome sequence data reveals that subclonal driver mutations predict poor prognosis in chronic lymphocytic leukemia.

Scott L. Carter, Dan-Avi Landau, Petar Stojanov, Aaron McKenna, Kristian Cibulskis, Michael S. Lawrence, Jens Lohr, Kristen Stevenson, Donna Neuberg, Matthew Meyerson, Catherine J. Wu, Gad Getz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4600.
https://doi.org/10.1158/1538-7445.AM2013-4600
Published: 15 April 2013
View articletitled, Abstract 4600: Analysis of clonal evolution in cancer using whole exome sequence data reveals that subclonal driver mutations predict poor prognosis in chronic lymphocytic leukemia.
Journal Articles

Abstract 4598: Identification of driver genes in hepatocellular carcinoma by exome sequencing.

Sean P. Cleary, William R. Jeck, Xiaobei Zhao, Sara R. Selitsky, Gleb L. Savich, Ting-Xu Tan, Michael C. Wu, Gad Getz, Michael S. Lawrence, Joel S. Parker, Jinyu Li, Scott Powers, Hyeja Kim, Sandra E. Fischer, Maha Guindi, Anand Ghanekar, Derek Y. Chiang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4598.
https://doi.org/10.1158/1538-7445.AM2013-4598
Published: 15 April 2013
View articletitled, Abstract 4598: Identification of driver genes in hepatocellular carcinoma by exome sequencing.
Journal Articles

Abstract 4017: Dissecting the clonal hierarchy of cancer-driving genomic lesions.

Davide Prandi, Sylvan C. Baca, Michael S. Lawrence, Juan Miguel Mosquera, Alessandro Romanel, Yotam Drier, Kyung Park, Naoki Kitabayashi, Theresa Y. MacDonald, Eliezer Van Allen, Gregory V. Kryukov, Jean-Philippe Theurillat, T. David Soong, Elizabeth Nickerson, Daniel Auclair, Ashutosh Tewari, Himisha Beltran, Robert C. Onofrio, Gunther Boysen, Candace Guiducci, Christopher E. Barbieri, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter, Gordon Saksena, Douglas Voet, Alex H. Ramos, Wendy Winckler, Michelle Cipicchio, Kristin Ardlie, Philip W. Kantoff, Michael F. Berger, Stacey B. Gabriel, Todd R. Golub, Matthew Meyerson, Eric S. Lander, Olivier Elemento, Gad Getz, Francesca Demichelis, Mark A. Rubin, Levi A. Garraway
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4017.
https://doi.org/10.1158/1538-7445.AM2013-4017
Published: 15 April 2013
View articletitled, Abstract 4017: Dissecting the clonal hierarchy of cancer-driving genomic lesions.