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Abstract 1029: MAPK-mediated immunomodulation in disseminated murine Emu-TCL1 chronic lymphocytic leukemia

Aparna Lakshmanan, Yo-Ting Tsai, Amy Lehman, Ellen J. Sass, Minh Tran, Fabienne Lucas, Meixiao Long, Bonnie K. Harrington, Krista La Perle, Vincenzo Coppola, Gerard Lozanski, Natarajan Muthusamy, John C. Byrd, Michael R. Grever, David M. Lucas

Cancer Res (2017) 77 (13_Supplement): 1029.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1029

Published: 01 July 2017

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Journal Articles

Abstract LB-254: PRMT5 is upregulated in malignant and metastatic melanoma, and regulates expression of the MITF transcription factor

Courtney Nicholas, Jennifer Yang, Sara B. Peters, Robert A. Baiocchi, Fengting Yan, Said Sif, Sookil Tae, Gregory S. Young, Michael R. Grever, Gregory B. Lesinski

Cancer Res (2012) 72 (8_Supplement): LB-254.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-254

Published: 15 April 2012

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Journal Articles

Abstract 5586: Phase I study of PARP inhibitor ABT-888 and carboplatin with novel imaging in metastatic breast cancer (MBC) (NCI-8609)

Cancer Res (2012) 72 (8_Supplement): 5586.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5586

Published: 15 April 2012

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Abstract 5473: The contribution of P-glycoprotein to clinical pharmacokinetic interactions between lenalidomide and temsirolimus

Xiaoxia Yang, Hofmeister C. Craig, Darlene M. Rozewski, Seungsoo Lee, Ping Chen, Amy J. Johnson, Zhongfa Liu, Erinn M. Hade, Jia Ji, Larry J. Schaaf, Don M. Benson, Eric H. Kraut, William J. Hicks, Kenneth K. Chan, Ching-Shih Chen, Sherif S. Farag, Michael R. Grever, John C. Byrd, Mitch A. Phelps

Cancer Res (2011) 71 (8_Supplement): 5473.

DOI: https://doi.org/10.1158/1538-7445.AM2011-5473

Published: 15 April 2011

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Journal Articles

Abstract 3558: The natural product silvestrol decreases oncogenic FLT3 and miR-155 levels in FLT3-ITD positive Acute Myeloid Leukemia (AML) cells

Houda Alachkar, Shujun Liu, Sebastian Schwind, Heiko Becker, Klaus H. Metzeler, Christopher Hickey, Jiuxia Pang, Susan P. Whitman, Kenneth K. Chan, Ramiro Garzon, David M. Lucas, Danilo Perrotti, Lai-Chu Wu, Michael R. Grever, A D. Kinghorn, Guido Marcucci

Cancer Res (2010) 70 (8_Supplement): 3558.

DOI: https://doi.org/10.1158/1538-7445.AM10-3558

Published: 15 April 2010

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Abstract 2594: Reovirus replication in ovarian and peritoneal tumors after intravenous administration

Mitch A. Phelps, David E. Cohn, David M. O'Malley, Lai Wei, Deidre Wilkins, Angela Campbell, Larry J. Schaaf, Matthew C. Coffey, Miguel A. Villalona-Calero, Michael R. Grever, Gerard J. Nuovo, James A. Zwiebel

Cancer Res (2010) 70 (8_Supplement): 2594.

DOI: https://doi.org/10.1158/1538-7445.AM10-2594

Published: 15 April 2010

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Silvestrol 5”’, 6”’-diacetate, a semi-synthetic rocaglate derivative from the Indonesian plant Aglaia foveolata, has anti-tumor activity against Chronic Lymphocytic Leukemia cells in vitro

David M. Lucas, Ryan B. Edwards, Bao-Ning Su, Thomas Lin, John C. Byrd, A. Douglas Kinghorn, Michael R. Grever

Cancer Res (2006) 66 (8_Supplement): 454.

Published: 15 April 2006

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Journal Articles

Clinical rebirth of flavopiridol in chronic lymphocytic leukemia (CLL): Utilizing in vitro and in vivo pharmacodynamic measurements to improve efficacy and interrogate relevant mechanism(s) of action

Amy J. Johnson, David M. Lucas, Lisa L. Smith, Jamie M. S. Allison, Thomas S. Lin, Michael R. Grever, John C. Byrd

Cancer Res (2005) 65 (9_Supplement): 394.

Published: 01 May 2005

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Journal Articles

Tumor Growth Inhibition Induced in a Murine Model of Human Burkitt's Lymphoma by a Proteasome Inhibitor

Robert Z. Orlowski, Jairam R. Eswara, Anne Lafond-Walker, Michael R. Grever, Marian Orlowski, Chi V. Dang

Cancer Res (1998) 58 (19): 4342–4348.

Published: 01 October 1998

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Journal Articles

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Angelika M. Burger, Gurmeet Kaur, Michael C. Alley, Jeffrey G. Supko, Louis Malspeis, Michael R. Grever, Edward A. Sausville

Cancer Res (1995) 55 (13): 2794–2799.

Published: 01 July 1995

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Journal Articles

Efficacy of the Quinocarmycins KW2152 and DX-52-1 against Human Melanoma Lines Growing in Culture and in Mice

Jacqueline Plowman, Donald J. Dykes, Ven L. Narayanan, Betty J. Abbott, Hiromitsu Saito, Tadashi Hirata, Michael R. Grever

Cancer Res (1995) 55 (4): 862–867.

Published: 01 February 1995

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Journal Articles

Preclinical Antitumor Activity of Temozolomide in Mice: Efficacy against Human Brain Tumor Xenografts and Synergism with 1,3-Bis(2-chloroethyl)-1-nitrosourea

Jacqueline Plowman, William R. Waud, Antonis D. Koutsoukos, Lawrence V. Rubinstein, Timothy D. Moore, Michael R. Grever

Cancer Res (1994) 54 (14): 3793–3799.

Published: 01 July 1994

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Journal Articles

Immunological Effects of Flavone Acetic Acid

Pierre L. Triozzi, John J. Rinehart, Louis Malspeis, Donn C. Young, Michael R. Grever

Cancer Res (1990) 50 (20): 6483–6485.

Published: 01 October 1990

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Journal Articles

Phase II Trial of 9-β-d-Arabinofuranosyl-2-fluoroadenine 5′-Monophosphate in Non-Hodgkin's Lymphoma: Prospective Comparison of Response with Deoxycytidine Kinase Activity¹

Jane M. Leiby, Kathy M. Snider, Eric H. Kraut, Earl N. Metz, Louis Malspeis, Michael R. Grever

Cancer Res (1987) 47 (10): 2719–2722.

Published: 01 May 1987

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Journal Articles

Adenosine Deaminase and Terminal Deoxynucleotidyl Transferase: Biochemical Markers in the Management of Chronic Myelogenous Leukemia

Michael R. Grever, Mary Sue Coleman, Stanley P. Balcerzak

Cancer Res (1983) 43 (3): 1442–1445.

Published: 01 March 1983

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NARROW

Abstract 1029: MAPK-mediated immunomodulation in disseminated murine Emu-TCL1 chronic lymphocytic leukemia

Abstract LB-254: PRMT5 is upregulated in malignant and metastatic melanoma, and regulates expression of the MITF transcription factor

Abstract 5586: Phase I study of PARP inhibitor ABT-888 and carboplatin with novel imaging in metastatic breast cancer (MBC) (NCI-8609)

Abstract 5473: The contribution of P-glycoprotein to clinical pharmacokinetic interactions between lenalidomide and temsirolimus

Abstract 3558: The natural product silvestrol decreases oncogenic FLT3 and miR-155 levels in FLT3-ITD positive Acute Myeloid Leukemia (AML) cells

Abstract 2594: Reovirus replication in ovarian and peritoneal tumors after intravenous administration

Silvestrol 5”’, 6”’-diacetate, a semi-synthetic rocaglate derivative from the Indonesian plant Aglaia foveolata, has anti-tumor activity against Chronic Lymphocytic Leukemia cells in vitro

Clinical rebirth of flavopiridol in chronic lymphocytic leukemia (CLL): Utilizing in vitro and in vivo pharmacodynamic measurements to improve efficacy and interrogate relevant mechanism(s) of action

Tumor Growth Inhibition Induced in a Murine Model of Human Burkitt's Lymphoma by a Proteasome Inhibitor

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Efficacy of the Quinocarmycins KW2152 and DX-52-1 against Human Melanoma Lines Growing in Culture and in Mice

Preclinical Antitumor Activity of Temozolomide in Mice: Efficacy against Human Brain Tumor Xenografts and Synergism with 1,3-Bis(2-chloroethyl)-1-nitrosourea

Immunological Effects of Flavone Acetic Acid

Phase II Trial of 9-β-d-Arabinofuranosyl-2-fluoroadenine 5′-Monophosphate in Non-Hodgkin's Lymphoma: Prospective Comparison of Response with Deoxycytidine Kinase Activity¹

Adenosine Deaminase and Terminal Deoxynucleotidyl Transferase: Biochemical Markers in the Management of Chronic Myelogenous Leukemia

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