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Michael Platten
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Journal Articles

Abstract 14: Identification of tumor-reactive T cell receptors through functional single cell interaction analyses for personalized T cell therapy

Tim Robin Wagner, Niklas Kehl, Simon Steiger, Michael Kilian, Bruno Schönfelder, Tamara Boschert, Katharina Lindner, Patrick Schmidt, Karsten Rippe, Hartmut Goldschmidt, Marc-Steffen Raab, Michael Platten, Mirco Friedrich, Stefan B. Eichmüller
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 14.
https://doi.org/10.1158/1538-7445.AM2024-14
Published: 22 March 2024
View article titled, Abstract 14: Identification of tumor-reactive T cell receptors through functional single cell interaction analyses for personalized T cell therapy
Journal Articles

Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR) inhibitor BAY2416964

Kyriakos Papadopoulos, Michael Cecchini, Juanita S. Lopez, Dirk Jäger, Ki Young Chung, Michael Platten, Florian Prinz, Yuko Ishii, David Schaer, Ilona Gutcher, Gabriele Leder, Radost Pencheva, Thomas Wagener, Christian Scheerans, Carsten Zieschang, Andrea Wagner, Spyros Stamatelos, Ecaterina Dumbrava
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT276.
https://doi.org/10.1158/1538-7445.AM2023-CT276
Published: 14 April 2023
View article titled, Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR) inhibitor BAY2416964
Journal Articles

Abstract 4071: Identification of myeloma-specific T cell receptors by functional single cell interaction analyses

Tim R. Wagner, Eren Boğa, Patrick Schmidt, Wolfram Osen, Michael Platten, Hartmut Goldschmidt, Marc S. Raab, Mirco J. Friedrich, Stefan B. Eichmüller
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4071.
https://doi.org/10.1158/1538-7445.AM2023-4071
Published: 04 April 2023
View article titled, Abstract 4071: Identification of myeloma-specific T cell receptors by functional single cell interaction analyses
Journal Articles

Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor

Ilona Gutcher, Christina Kober, Lars Roese, Julian Roewe, Norbert Schmees, Florian Prinz, Matyas Gorjanacz, Ulrike Roehn, Benjamin Bader, Horst Irlbacher, Detlef Stoeckigt, Rafael Carretero, Katharina Sahm, Iris Oezen, Hilmar Weinmann, Ingo V. Hartung, Bertolt Kreft, Michael Platten
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1288.
https://doi.org/10.1158/1538-7445.AM2019-1288
Published: 01 July 2019
View article titled, Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor
Journal Articles

Abstract 4454: Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression

Norbert Schmees, Ilona Gutcher, Ulrike Roehn, Horst Irlbacher, Detlef Stoeckigt, Benjamin Bader, Christina Kober, Lars Roese, Rafael Carretero, Iris Oezen, Ludiwg Zorn, Michael Platten, Ingo Volker Hartung, Bertolt Kreft, Hilmar Weinmann
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4454.
https://doi.org/10.1158/1538-7445.AM2019-4454
Published: 01 July 2019
View article titled, Abstract 4454: Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression
Journal Articles

Abstract 2654: GAPVAC-101 phase I trial: First data of an innovative actively personalized peptide vaccination trial in patients with newly diagnosed glioblastoma

Norbert Hilf, Katrin Frenzel, Sabrina Kuttruff-Coqui, Sandra Heesch, Sebastian Kreiter, Arie Admon, Valesca Bukur, Sjoerd van der Burg, Cecile Gouttefangeas, Judith R. Kroep, Marij Schoenmaekers-Welters, Jordi Piro, Berta Ponsati, Hans Skovgaard Poulsen, Ulrik Lassen, Francisco Martinez-Ricarte, Jordi Rodon, Juan Sahuquillo, Monika Stieglbauer, Stefan Stevanovic, Per thor Straten, Marco Skardelly, Ghazaleh Tabatabai, Michael Platten, David Capper, Andreas von Deimling, Valérie Dutoit, Hideho Okada, Christian Ottensmeier, Randi Kristina Feist, Jens Fritsche, Karoline Laske, Peter Lewandrowski, Martin Löwer, Regina Mendryzk, Miriam Meyer, Carsten Reinhardt, Bernhard Rössler, Anna Paruzynski, Nina Pawlowski, Colette Song, Stevermann Lea, Toni Weinschenk, Christoph Huber, Hans-Georg Rammensee, Pierre-Yves Dietrich, Wick Wolfgang, Ugur Sahin, Harpreet Singh-Jasuja
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2654.
https://doi.org/10.1158/1538-7445.AM2016-2654
Published: 15 July 2016
View article titled, Abstract 2654: GAPVAC-101 phase I trial: First data of an innovative actively personalized peptide vaccination trial in patients with newly diagnosed glioblastoma
Journal Articles

The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress

Felix Sahm, Iris Oezen, Christiane A. Opitz, Bernhard Radlwimmer, Andreas von Deimling, Tilman Ahrendt, Seray Adams, Helge B. Bode, Gilles J. Guillemin, Wolfgang Wick, Michael Platten
Journal: Cancer Research
Cancer Res (2013) 73 (11): 3225–3234.
https://doi.org/10.1158/0008-5472.CAN-12-3831
Published: 30 May 2013
View article titled, The Endogenous Tryptophan Metabolite and NAD<sup>+</sup> Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
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Includes: Supplementary data
Journal Articles

Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker.

Benedikt Wiestler, David Capper, Tim Holland-Letz, Andreas von Deimling, Stefan M. Pfister, Michael Platten, Michael Weller, Wolfgang Wick
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-80.
https://doi.org/10.1158/1538-7445.AM2013-LB-80
Published: 15 April 2013
View article titled, Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker.
Journal Articles

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

Michael Platten, Wolfgang Wick, Benoît J. Van den Eynde
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5435–5440.
https://doi.org/10.1158/0008-5472.CAN-12-0569
Published: 31 October 2012
View article titled, Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
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Journal Articles

Abstract LB-382: Inhibition of CD95 signalling by APG-101 enhances efficacy of radiotherapy (RT) and reduces RT-induced tumor satellite formation

Philipp N. Pfenning, Markus Weiler, Christian Merz, Manfred Jugold, Christian Gieffers, Michael Platten, Harald Fricke, Wolfgang Wick
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-382.
https://doi.org/10.1158/1538-7445.AM2011-LB-382
Published: 15 April 2011
View article titled, Abstract LB-382: Inhibition of CD95 signalling by APG-101 enhances efficacy of radiotherapy (RT) and reduces RT-induced tumor satellite formation
Journal Articles

SD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells In vitro and In vivo

Martin Uhl, Steffen Aulwurm, Jörg Wischhusen, Markus Weiler, Jing Ying Ma, Ramona Almirez, Ruban Mangadu, Yu-Wang Liu, Michael Platten, Ulrich Herrlinger, Alison Murphy, Darren H. Wong, Wolfgang Wick, Linda S. Higgins, Michael Weller
Journal: Cancer Research
Cancer Res (2004) 64 (21): 7954–7961.
https://doi.org/10.1158/0008-5472.CAN-04-1013
Published: 01 November 2004
View article titled, SD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells <em>In vitro</em> and <em>In vivo</em>
Open the PDF for SD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells <em>In vitro</em> and <em>In vivo</em> in another window
Journal Articles

MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas

Manuel A. Friese, Michael Platten, Stefan Z. Lutz, Ulrike Naumann, Steffen Aulwurm, Felix Bischof, Hans-Jörg Bühring, Johannes Dichgans, Hans-Georg Rammensee, Alexander Steinle, Michael Weller
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8996–9006.
Published: 24 December 2003
View article titled, MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas
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Journal Articles

Soluble Decoy Receptor 3 Is Expressed by Malignant Gliomas and Suppresses CD95 Ligand-induced Apoptosis and Chemotaxis

Wilfried Roth, Stefan Isenmann, Mitsutoshi Nakamura, Michael Platten, Wolfgang Wick, Paul Kleihues, Mathias Bähr, Hiroko Ohgaki, Avi Ashkenazi, Michael Weller
Journal: Cancer Research
Cancer Res (2001) 61 (6): 2759–2765.
Published: 03 March 2001
View article titled, Soluble Decoy Receptor 3 Is Expressed by Malignant Gliomas and Suppresses CD95 Ligand-induced Apoptosis and Chemotaxis
Open the PDF for Soluble Decoy Receptor 3 Is Expressed by Malignant Gliomas and Suppresses CD95 Ligand-induced Apoptosis and Chemotaxis in another window