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Michael Overholtzer
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Journal Articles

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

Open Access
Sunyana Gadal, Jacob A. Boyer, Simon F. Roy, Noah A. Outmezguine, Malvika Sharma, Hongyan Li, Ning Fan, Eric Chan, Yevgeniy Romin, Afsar Barlas, Qing Chang, Priya Pancholi, Neilawattie Merna Timaul, Michael Overholtzer, Rona Yaeger, Katia Manova-Todorova, Elisa de Stanchina, Marcus W. Bosenberg, Neal Rosen
Journal: Cancer Research
Cancer Res (2025) 85 (9): 1611–1627.
https://doi.org/10.1158/0008-5472.CAN-24-2220
Published: 02 May 2025
View articletitled, Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
Open the PDF for Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract A12: YAP‐dependent induction of amphiregulin identifies a non‐cell‐autonomous component of the Hippo pathway

Free
Jianmin Zhang, Jun‐Yuan Ji, Min Yu, Michael Overholtzer, Gromoslaw A. Smolen, Joan S. Brugge, Nicholas J. Dyson, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): A12.
https://doi.org/10.1158/0008-5472.FBCR09-A12
Published: 28 October 2014
View articletitled, Abstract A12: YAP‐dependent induction of amphiregulin identifies a non‐cell‐autonomous component of the Hippo pathway
Journal Articles

Abstract IA-13: Mechanisms regulating anchorage independent survival

Free
Zachary Schafer, Alex Grassian, Loling Song, Arnaud Mailleux, Tobias Schmelzle, Yoko Irie, Grace Gao, Michael Overholtzer, Zhenyang Jiang, Zachary Gerhart‐Hines, Pere Puigsever, Joan S. Brugge
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): IA-13.
https://doi.org/10.1158/0008-5472.FBCR09-IA-13
Published: 28 October 2014
View articletitled, Abstract IA-13: Mechanisms regulating anchorage independent survival
Journal Articles

Abstract SY29-03: Competition between tumor cells by entosis

Free
Qiang Sun, Tianzhi Luo, Yixin Ren, Oliver Florey, Edmund S. Cibas, Louis Hodgson, Douglas N. Robinson, Michael Overholtzer
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): SY29-03.
https://doi.org/10.1158/1538-7445.AM2014-SY29-03
Published: 01 October 2014
View articletitled, Abstract SY29-03: Competition between tumor cells by entosis
Journal Articles

Mechanisms of Ploidy Increase in Human Cancers: A New Role for Cell Cannibalism

Free
Matej Krajcovic, Michael Overholtzer
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1596–1601.
https://doi.org/10.1158/0008-5472.CAN-11-3127
Published: 01 April 2012
View articletitled, Mechanisms of Ploidy Increase in Human Cancers: A New Role for Cell Cannibalism
Open the PDF for Mechanisms of Ploidy Increase in Human Cancers: A New Role for Cell Cannibalism in another window
Journal Articles

Abstract SY09-03: Entosis: Adhesion, autophagy, and murder

Free
Michael Overholtzer
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): SY09-03.
https://doi.org/10.1158/1538-7445.AM2011-SY09-03
Published: 15 April 2011
View articletitled, Abstract SY09-03: Entosis: Adhesion, autophagy, and murder
Journal Articles

Abstract LB-228: YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

Free
Jianmin Zhang, Jun-Yuan Ji, Min Yi, Michael Overholtzer, Gromoslaw A. Smolen, Rececca Wang, Joan S. Brugge, Nicholas J. Dyson, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-228.
https://doi.org/10.1158/1538-7445.AM10-LB-228
Published: 15 April 2010
View articletitled, Abstract LB-228: YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
Journal Articles

Abstract #LB-272: A novel dose-dependent regulation of matrix adhesion by Notch that controls outgrowth of hyperproliferative structures

Free
Marco Mazzone, Laura Selfors, Darshan Pandya, Michael Overholtzer, Joan Brugge
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-272.
Published: 01 May 2009
View articletitled, Abstract #LB-272: A novel dose-dependent regulation of matrix adhesion by Notch that controls outgrowth of hyperproliferative structures
Journal Articles

A non-apoptotic cell death process, entosis, that occurs by cell-in-cell invasion.

Free
Michael Overholtzer, Arnaud Mailleux, Ghassan Mouneimne, Guillaume Normand, Stuart Schnitt, Randall King, Edmund Cibas, Joan Brugge
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1560.
Published: 01 May 2008
View articletitled, A non-apoptotic cell death process, entosis, that occurs by cell-in-cell invasion.
Journal Articles

Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast cancer

Free
Chuanwei Yang, Sally Trent, Michael Overholtzer, Dennis Sgroi, Emmett V. Schmidt
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1246.
Published: 01 May 2005
View articletitled, Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast cancer