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Michael Ohlmeyer
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Journal Articles

Abstract 6444: PP2A activation targets PAI-1/CCL2 to suppress therapy-induced senescence in neuroblastoma

Free
Nazia Nazam, Maryam Ghufran, Morgan L. Brown, Sorina Shirley, Jerry E. Stewart, Michael Ohlmeyer, Taylor Schanel, Elizabeth A. Beierle
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6444.
https://doi.org/10.1158/1538-7445.AM2025-6444
Published: 21 April 2025
View articletitled, Abstract 6444: PP2A activation targets PAI-1/CCL2 to suppress therapy-induced senescence in neuroblastoma
Journal Articles

Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma

Free
Brittany L. Allen-Petersen, Tyler Risom, Zipei Feng, Zhiping Wang, Zina P. Jenny, Mary C. Thoma, Katherine R. Pelz, Jennifer P. Morton, Owen J. Sansom, Charles D. Lopez, Brett Sheppard, Dale J. Christensen, Michael Ohlmeyer, Goutham Narla, Rosalie C. Sears
Journal: Cancer Research
Cancer Res (2019) 79 (1): 209–219.
https://doi.org/10.1158/0008-5472.CAN-18-0717
Published: 02 January 2019
View articletitled, Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma
Open the PDF for Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1827: Direct activation of the tumor suppressor protein phosphatase 2A as a therapeutic strategy for TKI-resistant lung adenocarcinoma

Free
Rita Tohme, Jaya Sangodkar, Neil Dhawan, Sudeh Izadmeher, Neelesh Sharma, Michael Ohlmeyer, Goutham Narla
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1827.
https://doi.org/10.1158/1538-7445.AM2018-1827
Published: 01 July 2018
View articletitled, Abstract 1827: Direct activation of the tumor suppressor protein phosphatase 2A as a therapeutic strategy for TKI-resistant lung adenocarcinoma
Journal Articles

Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

Free
Kimberly McClinch, Rita A. Avelar, David Callejas, Sudeh Izadmehr, Danica Wiredja, Abbey Perl, Jaya Sangodkar, David B. Kastrinsky, Daniela Schlatzer, Maxwell Cooper, Janna Kiselar, Agnes Stachnik, Shen Yao, Divya Hoon, Daniel McQuaid, Nilesh Zaware, Yixuan Gong, David L. Brautigan, Stephen R. Plymate, Cynthia C.T. Sprenger, William K. Oh, Alice C. Levine, Alexander Kirschenbaum, John P. Sfakianos, Rosalie Sears, Analisa DiFeo, Yiannis Ioannou, Michael Ohlmeyer, Goutham Narla, Matthew D. Galsky
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2065–2080.
https://doi.org/10.1158/0008-5472.CAN-17-0123
Published: 12 April 2018
View articletitled, Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer
Open the PDF for Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4173: Drug target mutations as a mechanism of acquired resistance to small molecules activators of protein phosphatase 2a

Free
Rita Tohme, Jaya Sangodkar, Janna Kiselar, Daniel Leonard, Caitlin O'Connor, Sai Gandhe, Wenqing Xu, David Brautigan, Mark Chance, Michael Ohlmeyer, Goutham Narla
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4173.
https://doi.org/10.1158/1538-7445.AM2017-4173
Published: 01 July 2017
View articletitled, Abstract 4173: Drug target mutations as a mechanism of acquired resistance to small molecules activators of protein phosphatase 2a
Journal Articles

Abstract 3865: Therapeutic activation of protein phosphatase 2A for the treatment of lung cancer

Free
Jaya Sangodkar, Rita Tohme, Janna Kiselar, Sudeh Izadmehr, Divya Hoon, Sahar Mazhar, Abbey Perl, Danica Wiredja, Daniela Schlatzer, Shen Yao, David Kastrinsky, Neelesh Sharma, David Brautigan, Mark Chance, Alain Borczuk, Michael Ohlmeyer, Yiannis Ioannou, Goutham Narla
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3865.
https://doi.org/10.1158/1538-7445.AM2016-3865
Published: 15 July 2016
View articletitled, Abstract 3865: Therapeutic activation of protein phosphatase 2A for the treatment of lung cancer
Journal Articles

Abstract 5329: Development of small molecule activators of protein phosphatase 2A for the treatment of lung cancer

Free
Jaya Sangodkar, Sudeh Izadmehr, Sahar Mahzar, Divya Hoon, Shen Yao, David Kastrinsky, Daniela Schlatzer, Neelesh Sharma, Alain C. Borczuk, Michael Ohlmeyer, Yiannis Ioannou, Goutham Narla
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5329.
https://doi.org/10.1158/1538-7445.AM2015-5329
Published: 01 August 2015
View articletitled, Abstract 5329: Development of small molecule activators of protein phosphatase 2A for the treatment of lung cancer
Journal Articles

Abstract SY38-03: Targeting post-translational activation of MYC for the treatment of cancer

Free
Xiaoyan Wang, Amy Farrell, Mahnaz Janghorban, Brittany Allen-Petersen, Juan Liang, Tyler Risom, Michael Ohlmeyer, Goutham Narla, Rosalie C. Sears
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): SY38-03.
https://doi.org/10.1158/1538-7445.AM2015-SY38-03
Published: 01 August 2015
View articletitled, Abstract SY38-03: Targeting post-translational activation of MYC for the treatment of cancer
Journal Articles

Abstract A10: BRD4 is a new therapeutic target in melanoma

Free
Barbara Fontanals-Cirera, Miguel F. Segura, Avital Gaziel-Sovran, Maria V. Guijarro, Doug Hanniford, Pilar Gonzalez-Gomez, Weijia Zhang, Guantao Zhang, Farbod Darvishian, Michael Ohlmeyer, Iman Osman, Ming-Ming Zhou, Eva Hernando
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A10.
https://doi.org/10.1158/1538-7445.CEC13-A10
Published: 13 May 2014
View articletitled, Abstract A10: BRD4 is a new therapeutic target in melanoma
Journal Articles

BRD4 Sustains Melanoma Proliferation and Represents a New Target for Epigenetic Therapy

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Miguel F. Segura, Bárbara Fontanals-Cirera, Avital Gaziel-Sovran, María V. Guijarro, Doug Hanniford, Guangtao Zhang, Pilar González-Gomez, Marta Morante, Luz Jubierre, Weijia Zhang, Farbod Darvishian, Michael Ohlmeyer, Iman Osman, Ming-Ming Zhou, Eva Hernando
Journal: Cancer Research
Cancer Res (2013) 73 (20): 6264–6276.
https://doi.org/10.1158/0008-5472.CAN-13-0122-T
Published: 14 October 2013
View articletitled, BRD4 Sustains Melanoma Proliferation and Represents a New Target for Epigenetic Therapy
Open the PDF for BRD4 Sustains Melanoma Proliferation and Represents a New Target for Epigenetic Therapy in another window
Journal Articles

Abstract 1885: Targeting the FOXO1/KLF6 transcriptional network to modulate response to anti-EGFR based therapy

Free
Jaya Sangodkar, Neil Dhawan, Heather Melville, Varan J. Singh, Caroline Farrington, Eric Yuan, Huma Rana, Blake Smith, Vickram Gidwani, Rachel Okrent, David Burstein, Michael Ohlmeyer, Katerina Politi, Analisa DiFeo, Goutham Narla
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1885.
https://doi.org/10.1158/1538-7445.AM2012-1885
Published: 15 April 2012
View articletitled, Abstract 1885: Targeting the FOXO1/KLF6 transcriptional network to modulate response to anti-EGFR based therapy