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Journal Articles

Abstract 4460: Investigating a non-canonical role for SHP2 in pancreatic ductal adenocarcinoma metabolism and response to dietary modifications

R. McKinnon Walsh, Jarrid L. Jack, Austin E. Eades, Bailey A. Bye, Mariana T. Ruckert, Joseph Ambrose, Michael N. VanSaun

Cancer Res (2024) 84 (6_Supplement): 4460.

https://doi.org/10.1158/1538-7445.AM2024-4460

Published: 22 March 2024

View article titled, Abstract 4460: Investigating a non-canonical role for SHP2 in pancreatic ductal adenocarcinoma metabolism and response to dietary modifications

Journal Articles

Abstract A110: Clec4f is expressed in a subset of primary PDAC cells and confers invasive behavior

Bailey A. Bye, Richard M. Walsh, Austin E. Eades, Michael N. VanSaun

Cancer Res (2024) 84 (2_Supplement): A110.

https://doi.org/10.1158/1538-7445.PANCA2023-A110

Published: 16 January 2024

View article titled, Abstract A110: Clec4f is expressed in a subset of primary PDAC cells and confers invasive behavior

Journal Articles

Abstract C060: Adipose-tumor crosstalk alters tumor immune profile by promoting PDAC CXCL5 secretion

R. McKinnon Walsh, Joseph Ambrose, Bailey A. Bye, Austin E. Eades, Jarrid L. Jack, Mariana T. Ruckert, Appolinaire A. Olou, Fanuel Messaggio, Prabhakar Chalise, Dong Pei, Michael N. VanSaun

Cancer Res (2022) 82 (22_Supplement): C060.

https://doi.org/10.1158/1538-7445.PANCA22-C060

Published: 15 November 2022

View article titled, Abstract C060: Adipose-tumor crosstalk alters tumor immune profile by promoting PDAC CXCL5 secretion

Journal Articles

Abstract 4027: Dual MEK and AKT inhibition suppresses pancreatic cancer growth and migration

Jarrid Jack, Alexandra Pierce, Bailey Bye, McKinnon Walsh, Prabhakar Chalise, Michael N. VanSaun

Cancer Res (2022) 82 (12_Supplement): 4027.

https://doi.org/10.1158/1538-7445.AM2022-4027

Published: 15 June 2022

View article titled, Abstract 4027: Dual MEK and AKT inhibition suppresses pancreatic cancer growth and migration

Journal Articles

Abstract 157: DUSP6 modulates migration and glycolysis in PDAC cells

Mariana T. Ruckert, Bailey A. Bye, Michael N. VanSaun, Vanessa S. Silveira

Cancer Res (2022) 82 (12_Supplement): 157.

https://doi.org/10.1158/1538-7445.AM2022-157

Published: 15 June 2022

View article titled, Abstract 157: DUSP6 modulates migration and glycolysis in PDAC cells

Journal Articles

Abstract 3168: Pancreatic cancer lipid theft is mediated by MAP Kinase signaling in adipocytes

Joseph Ambrose, Austin E. Eades, McKinnon Walsh, Michael N. VanSaun

Cancer Res (2021) 81 (13_Supplement): 3168.

https://doi.org/10.1158/1538-7445.AM2021-3168

Published: 01 July 2021

View article titled, Abstract 3168: Pancreatic cancer lipid theft is mediated by MAP Kinase signaling in adipocytes

Journal Articles

Abstract 2467: Adiponectin receptor agonism induces a metabolic switch in pancreatic cancer cells from oxidative phosphorylation to glycolysis

Sharon J. Manley, Jarrid Jack, Joseph Ambrose, Appolinaire A. Olou, Michael N. VanSaun

Cancer Res (2021) 81 (13_Supplement): 2467.

https://doi.org/10.1158/1538-7445.AM2021-2467

Published: 01 July 2021

View article titled, Abstract 2467: Adiponectin receptor agonism induces a metabolic switch in pancreatic cancer cells from oxidative phosphorylation to glycolysis

Journal Articles

Abstract 2824: SHP2-PDHA metabolic axis is critical for adipocyte function by mitigating ER stress-induced adipocytes dysfunction: Implication for obesity-driven pancreatic ductal adenocarcinoma progression

Appolinaire A. Olou, Jarrid Jack, Sharon Manley, Joseph Ambrose, McKinnon Walsh, Austin Eades, Michael N. VanSaun

Cancer Res (2021) 81 (13_Supplement): 2824.

https://doi.org/10.1158/1538-7445.AM2021-2824

Published: 01 July 2021

View article titled, Abstract 2824: SHP2-PDHA metabolic axis is critical for adipocyte function by mitigating ER stress-induced adipocytes dysfunction: Implication for obesity-driven pancreatic ductal adenocarcinoma progression

Journal Articles

Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer

Nagaraj S. Nagathihalli, Jason A. Castellanos, Purushottam Lamichhane, Fanuel Messaggio, Chanjuan Shi, Xizi Dai, Priyamvada Rai, Xi Chen, Michael N. VanSaun, Nipun B. Merchant

Cancer Res (2018) 78 (21): 6235–6246.

https://doi.org/10.1158/0008-5472.CAN-18-0634

Published: 01 November 2018

View article titled, Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer

Journal Articles

Abstract 2802: High fat diet increases development of hepatocellular carcinoma in glycine N-methyltransferase deficient mice

Michael N. VanSaun, Alisha Mendonsa, Fanuel Messaggio, Nagaraj Nagathihalli, Lee Gorden

Cancer Res (2017) 77 (13_Supplement): 2802.

https://doi.org/10.1158/1538-7445.AM2017-2802

Published: 01 July 2017

View article titled, Abstract 2802: High fat diet increases development of hepatocellular carcinoma in glycine N-methyltransferase deficient mice

Journal Articles

Abstract A46: AdipoRon suppresses ERK and STAT3 to inhibit pancreatic cancer growth

Fanuel Messaggio, Alisha M. Mendonsa, Jason A. Castellanos, Casey Roberts, Nagaraj S. Nagathihalli, Nipun B. Merchant, Lee D. Gorden, Michael N. VanSaun

Cancer Res (2016) 76 (24_Supplement): A46.

https://doi.org/10.1158/1538-7445.PANCA16-A46

Published: 14 December 2016

View article titled, Abstract A46: AdipoRon suppresses ERK and STAT3 to inhibit pancreatic cancer growth

Journal Articles

Abstract B75: Targeting the immune-microenvironment with combined inhibition of MEK and STAT3 in a mouse model of pancreatic cancer

Casey Roberts, Michael N. VanSaun, Purushottam Lamichhane, Fanuel Messaggio, Krisztina Kovacs, Supriya Srinivasan, Xizi Dai, Jennifer Barretta, Nagaraj Nagathihalli, Nipun B. Merchant

Cancer Res (2016) 76 (24_Supplement): B75.

https://doi.org/10.1158/1538-7445.PANCA16-B75

Published: 14 December 2016

View article titled, Abstract B75: Targeting the immune-microenvironment with combined inhibition of MEK and STAT3 in a mouse model of pancreatic cancer

Journal Articles

Abstract 4984: Contribution of MMP13 to tumor development in the steatotic liver microenvironment

Alisha Maria Mendonsa, Michael N. VanSaun, Lee Gorden

Cancer Res (2014) 74 (19_Supplement): 4984.

https://doi.org/10.1158/1538-7445.AM2014-4984

Published: 01 October 2014

View article titled, Abstract 4984: Contribution of MMP13 to tumor development in the steatotic liver microenvironment

Journal Articles

Abstract A90: Adiponectin deficiency enhances pancreatic cancer growth.

Alisha Mendonsa, Madeleine C. Chalfant, Lee Gorden, Michael N. VanSaun

Cancer Res (2012) 72 (14_Supplement): A90.

https://doi.org/10.1158/1538-7445.PANCA2012-A90

Published: 03 April 2014

View article titled, Abstract A90: Adiponectin deficiency enhances pancreatic cancer growth.

Journal Articles

Abstract 299: Modulation of the leptin receptor in pancreatic cancer cells mediates tumor growth

Alisha Mendonsa, Madeleine Chalfant, Nagaraj Nagathihalli, Nipun Merchant, Lee Gorden, Michael N. VanSaun

Cancer Res (2012) 72 (8_Supplement): 299.

https://doi.org/10.1158/1538-7445.AM2012-299

Published: 15 April 2012

View article titled, Abstract 299: Modulation of the leptin receptor in pancreatic cancer cells mediates tumor growth

Journal Articles

Abstract 1947: Self-reporting dendritic nanoparticles (nanodendrons) for drug delivery targeted to the tumor microenvironment and with reduced neurotoxicity

Lynn E. Samuelson, Randy L. Scherer, Carter J. Kathy, E Ashley Dozier, Sheree Printz, Michael N. VanSaun, Kang-Hsien Fan, Y Shyr, Paul E. Matrisian, Darryl J. Bornhop, Lynn M. Matrisian, J Oliver McIntyre

Cancer Res (2012) 72 (8_Supplement): 1947.

https://doi.org/10.1158/1538-7445.AM2012-1947

Published: 15 April 2012

View article titled, Abstract 1947: Self-reporting dendritic nanoparticles (nanodendrons) for drug delivery targeted to the tumor microenvironment and with reduced neurotoxicity

Journal Articles

Abstract 389: MMP12 and myeloid cell populations influence establishment of tumor metastases in the steatotic liver microenvironment

Alisha M. Mendonsa, Madeleine Chalfant, Michael N. VanSaun, Lynn Matrisian, David L. Gorden

Cancer Res (2012) 72 (8_Supplement): 389.

https://doi.org/10.1158/1538-7445.AM2012-389

Published: 15 April 2012

View article titled, Abstract 389: MMP12 and myeloid cell populations influence establishment of tumor metastases in the steatotic liver microenvironment

Journal Articles

Abstract 390: Increased orthotopic pancreatic tumor cell growth in obese mice

Lee Gorden, Michael N. VanSaun

Cancer Res (2011) 71 (8_Supplement): 390.

https://doi.org/10.1158/1538-7445.AM2011-390

Published: 15 April 2011

View article titled, Abstract 390: Increased orthotopic pancreatic tumor cell growth in obese mice

Journal Articles

Abstract LB-378: Establishment of hepatic metastases in a steatotic microenvironment is enhanced by stromal derived MMP-12

Michael N. VanSaun, Alisha Mendonsa, In Kyu Lee, Lynn M. Matrisian, Lee Gorden

Cancer Res (2010) 70 (8_Supplement): LB-378.

https://doi.org/10.1158/1538-7445.AM10-LB-378

Published: 15 April 2010

View article titled, Abstract LB-378: Establishment of hepatic metastases in a steatotic microenvironment is enhanced by stromal derived MMP-12

Journal Articles

Metastasis Research Society–American Association for Cancer Research Joint Conference on Metastasis

Danny R. Welch, Carlton R. Cooper, Douglas R. Hurst, Conor C. Lynch, Michelle D. Martin, Kedar S. Vaidya, Michael N. VanSaun, Andrea M. Mastro

Cancer Res (2008) 68 (23): 9578–9582.

https://doi.org/10.1158/0008-5472.CAN-08-3360

Published: 01 December 2008

View article titled, Metastasis Research Society–American Association for Cancer Research Joint Conference on Metastasis

NARROW

Abstract 4460: Investigating a non-canonical role for SHP2 in pancreatic ductal adenocarcinoma metabolism and response to dietary modifications

Abstract A110: Clec4f is expressed in a subset of primary PDAC cells and confers invasive behavior

Abstract C060: Adipose-tumor crosstalk alters tumor immune profile by promoting PDAC CXCL5 secretion

Abstract 4027: Dual MEK and AKT inhibition suppresses pancreatic cancer growth and migration

Abstract 157: DUSP6 modulates migration and glycolysis in PDAC cells

Abstract 3168: Pancreatic cancer lipid theft is mediated by MAP Kinase signaling in adipocytes

Abstract 2467: Adiponectin receptor agonism induces a metabolic switch in pancreatic cancer cells from oxidative phosphorylation to glycolysis

Abstract 2824: SHP2-PDHA metabolic axis is critical for adipocyte function by mitigating ER stress-induced adipocytes dysfunction: Implication for obesity-driven pancreatic ductal adenocarcinoma progression

Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer

Abstract 2802: High fat diet increases development of hepatocellular carcinoma in glycine N-methyltransferase deficient mice

Abstract A46: AdipoRon suppresses ERK and STAT3 to inhibit pancreatic cancer growth

Abstract B75: Targeting the immune-microenvironment with combined inhibition of MEK and STAT3 in a mouse model of pancreatic cancer

Abstract 4984: Contribution of MMP13 to tumor development in the steatotic liver microenvironment

Abstract A90: Adiponectin deficiency enhances pancreatic cancer growth.

Abstract 299: Modulation of the leptin receptor in pancreatic cancer cells mediates tumor growth

Abstract 1947: Self-reporting dendritic nanoparticles (nanodendrons) for drug delivery targeted to the tumor microenvironment and with reduced neurotoxicity

Abstract 389: MMP12 and myeloid cell populations influence establishment of tumor metastases in the steatotic liver microenvironment

Abstract 390: Increased orthotopic pancreatic tumor cell growth in obese mice

Abstract LB-378: Establishment of hepatic metastases in a steatotic microenvironment is enhanced by stromal derived MMP-12

Metastasis Research Society–American Association for Cancer Research Joint Conference on Metastasis

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