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Michael L. Gatza
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Journal Articles

Abstract P6-11-05: Carnitine palmitoyltransferase 1A (CPT1A) mediates therapeutic response to endocrine therapy in estrogen receptor positive breast cancer

Shaimaa Hussein, Michael L. Gatza, Shridar Ganesan
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-11-05.
https://doi.org/10.1158/1538-7445.SABCS22-P6-11-05
Published: 01 March 2023
View article titled, Abstract P6-11-05: Carnitine palmitoyltransferase 1A (CPT1A) mediates therapeutic response to endocrine therapy in estrogen receptor positive breast cancer
Journal Articles

Abstract 2456: SOX4 and SMARCA4 upregulate glycolysis-driven tumor proliferation through Hexokinase 2 in triple negative breast cancer

Pooja Khanna, Gaurav Mehta, Vrushank Bhatt, Jessie Y. Guo, Michael L. Gatza
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2456.
https://doi.org/10.1158/1538-7445.AM2021-2456
Published: 01 July 2021
View article titled, Abstract 2456: SOX4 and SMARCA4 upregulate glycolysis-driven tumor proliferation through Hexokinase 2 in triple negative breast cancer
Journal Articles

Abstract PD15-09: Sox4 and smarca4 upregulate glycolysis-driven tumor proliferation through hexokinase 2 in tnbc

Pooja Khanna, Gaurav Mehta, Michael L Gatza
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD15-09.
https://doi.org/10.1158/1538-7445.SABCS20-PD15-09
Published: 15 February 2021
View article titled, Abstract PD15-09: Sox4 and smarca4 upregulate glycolysis-driven tumor proliferation through hexokinase 2 in tnbc
Journal Articles

Abstract PO-035: SOX4 and SMARCA4 upregulate glycolysis-driven tumor proliferation through Hexokinase 2 in Triple Negative Breast Cancer

Pooja Khanna, Gaurav Mehta, Vrushank Bhatt, Jessie Y. Guo, Michael L. Gatza
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-035.
https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-035
Published: 02 December 2020
View article titled, Abstract PO-035: SOX4 and SMARCA4 upregulate glycolysis-driven tumor proliferation through Hexokinase 2 in Triple Negative Breast Cancer
Journal Articles

Abstract 5858: Multiplatform analyses identify upregulated hematopoietic cell kinase activity in poorly prognostic high-grade serous ovarian cancer and its role in regulating tumor aggressiveness

Christen A. Khella, Michael L. Gatza
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5858.
https://doi.org/10.1158/1538-7445.AM2020-5858
Published: 15 August 2020
View article titled, Abstract 5858: Multiplatform analyses identify upregulated hematopoietic cell kinase activity in poorly prognostic high-grade serous ovarian cancer and its role in regulating tumor aggressiveness
Journal Articles

Abstract P3-03-02: Integrative proteogenomic analyses identifies CPT1A and fatty acid oxidation as a potential therapeutic strategy in hormone receptor positive breast cancer

Michael L Gatza, Vrushank Bhatt, Kimberly Parker, Guarav Mehta, Christen Khella, Yanxiang Guo, Nidhi Jariwala
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-03-02.
https://doi.org/10.1158/1538-7445.SABCS19-P3-03-02
Published: 15 February 2020
View article titled, Abstract P3-03-02: Integrative proteogenomic analyses identifies <em>CPT1A</em> and fatty acid oxidation as a potential therapeutic strategy in hormone receptor positive breast cancer
Journal Articles

SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium

Ansu O. Perekatt, Pooja P. Shah, Shannon Cheung, Nidhi Jariwala, Alex Wu, Vishal Gandhi, Namit Kumar, Qiang Feng, Neeket Patel, Lei Chen, Shilpy Joshi, Anbo Zhou, M. Mark Taketo, Jinchuan Xing, Eileen White, Nan Gao, Michael L. Gatza, Michael P. Verzi
Journal: Cancer Research
Cancer Res (2018) 78 (17): 4878–4890.
https://doi.org/10.1158/0008-5472.CAN-18-0043
Published: 04 September 2018
View article titled, SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium
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Includes: Supplementary data
Journal Articles

New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging

Hailey E. Brighton, Steven P. Angus, Tao Bo, Jose Roques, Alicia C. Tagliatela, David B. Darr, Kubra Karagoz, Noah Sciaky, Michael L. Gatza, Norman E. Sharpless, Gary L. Johnson, James E. Bear
Journal: Cancer Research
Cancer Res (2018) 78 (2): 542–557.
https://doi.org/10.1158/0008-5472.CAN-17-1653
Published: 15 January 2018
View article titled, New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging
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Includes: Supplementary data
Journal Articles

NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress–Induced DPP3–KEAP1 Interaction

Kevin Lu, Allen L. Alcivar, Jianglin Ma, Tzeh Keong Foo, Susan Zywea, Amar Mahdi, Yanying Huo, Thomas W. Kensler, Michael L. Gatza, Bing Xia
Journal: Cancer Research
Cancer Res (2017) 77 (11): 2881–2892.
https://doi.org/10.1158/0008-5472.CAN-16-2204
Published: 31 May 2017
View article titled, NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress–Induced DPP3–KEAP1 Interaction
Open the PDF for NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress–Induced DPP3–KEAP1 Interaction in another window
Includes: Supplementary data
Journal Articles

Abstract S2-04: Comprehensive molecular characterization of invasive lobular breast tumors

Giovanni Ciriello, Michael L Gatza, Katherine A Hoadley, Hailei Zhang, Suhn K Rhie, Reanne Bowlby, Matthew D Wilkerson, Cyriac Kandoth, Michael McLellan, Andrew Cherniack, Peter W Laird, Chris Sander, Tari A King, Charles M Perou
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): S2-04.
https://doi.org/10.1158/1538-7445.SABCS14-S2-04
Published: 01 May 2015
View article titled, Abstract S2-04: Comprehensive molecular characterization of invasive lobular breast tumors
Journal Articles

Abstract 970: Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer

Christian D. Young, Lisa J. Zimmerman, Michael L. Gatza, Meghan M. Morrison, Corbin A. Whitwell, Neil E. Bhola, Ariella B. Hanker, Thomas Stricker, Premal Patel, Dana M. Brantley-Sieders, Charles M. Perou, Ben H. Park, Daniel C. Liebler, Rebecca S. Cook, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 970.
https://doi.org/10.1158/1538-7445.AM2014-970
Published: 01 October 2014
View article titled, Abstract 970: Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer
Journal Articles

FOXO Transcription Factors Control E2F1 Transcriptional Specificity and Apoptotic Function

Igor Shats, Michael L. Gatza, Beiyu Liu, Steven P. Angus, Lingchong You, Joseph R. Nevins
Journal: Cancer Research
Cancer Res (2013) 73 (19): 6056–6067.
https://doi.org/10.1158/0008-5472.CAN-13-0453
Published: 01 October 2013
View article titled, FOXO Transcription Factors Control E2F1 Transcriptional Specificity and Apoptotic Function
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Includes: Supplementary data
Journal Articles

Abstract 5123: An integrated genomics approach to identify novel drivers of oncogenic pathway activity in human cancer

Michael L. Gatza, So Young Kim, Jason Reeves, Joseph E. Lucas, Joseph R. Nevins
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5123.
https://doi.org/10.1158/1538-7445.AM2012-5123
Published: 15 April 2012
View article titled, Abstract 5123: An integrated genomics approach to identify novel drivers of oncogenic pathway activity in human cancer
Journal Articles

Using a Stem Cell–Based Signature to Guide Therapeutic Selection in Cancer

Igor Shats, Michael L. Gatza, Jeffrey T. Chang, Seiichi Mori, Jialiang Wang, Jeremy Rich, Joseph R. Nevins
Journal: Cancer Research
Cancer Res (2011) 71 (5): 1772–1780.
https://doi.org/10.1158/0008-5472.CAN-10-1735
Published: 01 March 2011
View article titled, Using a Stem Cell–Based Signature to Guide Therapeutic Selection in Cancer
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Includes: Supplementary data
Journal Articles

Stress induced mono-ubiquitination of HTLV-I Tax affects subcellular distribution and host cell protein interactions

Michael L. Gatza, Susan J. Marriott
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 603.
Published: 15 April 2006
View article titled, Stress induced mono-ubiquitination of HTLV-I Tax affects subcellular distribution and host cell protein interactions