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Michael Ittmann
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Journal Articles

Abstract 2077: Exploring the multifaceted efficacy of de novo lipogenesis inhibitor in cancer therapy

Dallin Lowder, Jin Na Shin, Maria E. Ruiz-Echartea, Jenny Deng, Aleksandra Rusin, Darlene Skapura, Michael Ittmann, Salma Kaochar
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2077.
https://doi.org/10.1158/1538-7445.AM2024-2077
Published: 22 March 2024
View articletitled, Abstract 2077: Exploring the multifaceted efficacy of de novo lipogenesis inhibitor in cancer therapy
Journal Articles

Abstract A037: Kinase GRK3 connects angiogenesis and neuroendocrine differentiation in prostate cancer progression by enhancing epigenetic activity of HDAC2

Samira Naderinezhad, Zheng Wang, Guoliang Zhang, Michael Ittmann, Martin Gleave, Wenliang Li
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A037.
https://doi.org/10.1158/1538-7445.PRCA2023-A037
Published: 02 June 2023
View articletitled, Abstract A037: Kinase GRK3 connects angiogenesis and neuroendocrine differentiation in prostate cancer progression by enhancing epigenetic activity of HDAC2
Journal Articles

Abstract 442: Developing a lipogenesis inhibitor for prostate cancer

Dallin Lowder, Jin Na Shin, Maria E. Ruiz-Echartea, Darlene Skapura, Jenny Deng, Aleksandra Rusin, Christel Davis, Erik Ehli, Cristian Coarfa, Michael Ittmann, Salma Kaochar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 442.
https://doi.org/10.1158/1538-7445.AM2023-442
Published: 04 April 2023
View articletitled, Abstract 442: Developing a lipogenesis inhibitor for prostate cancer
Journal Articles

Abstract 5999: Comparative and integrative analysis of transcriptomic and epigenome wide DNA methylation changes in African American prostate cancer

Bernard Kwabi-Addo, Somiranjan Ghosh, Chad Creighton, Michael Ittmann
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5999.
https://doi.org/10.1158/1538-7445.AM2023-5999
Published: 04 April 2023
View articletitled, Abstract 5999: Comparative and integrative analysis of transcriptomic and epigenome wide DNA methylation changes in African American prostate cancer
Journal Articles

The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response

Jacob E. Berchuck, Elio Adib, Sarah Abou Alaiwi, Amit K. Dash, Jin Na Shin, Dallin Lowder, Collin McColl, Patricia Castro, Ryan Carelli, Elisa Benedetti, Jenny Deng, Matthew Robertson, Sylvan C. Baca, Connor Bell, Heather M. McClure, Talal El Zarif, Matthew P. Davidsohn, Gitanjali Lakshminarayanan, Kinza Rizwan, Darlene G. Skapura, Sandra L. Grimm, Christel M. Davis, Erik A. Ehli, Kaitlin M. Kelleher, Ji-Heui Seo, Nicholas Mitsiades, Cristian Coarfa, Mark M. Pomerantz, Massimo Loda, Michael Ittmann, Matthew L. Freedman, Salma Kaochar
Journal: Cancer Research
Cancer Res (2022) 82 (16): 2848–2859.
https://doi.org/10.1158/0008-5472.CAN-21-3552
Published: 16 August 2022
View articletitled, The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
Open the PDF for The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response in another window
Includes: Supplementary data
Journal Articles

Abstract 186: Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers

Yan Zhang, Dayong Zheng, Ting Zhou, Mohit Hulsurkar, Michael Ittmann, Long Shao, Martin Gleave, Wenliang Li
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 186.
https://doi.org/10.1158/1538-7445.AM2019-186
Published: 01 July 2019
View articletitled, Abstract 186: Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers
Journal Articles

Abstract 1565: A novel therapeutic target in lethal prostate cancer in African American males

Salma Kaochar, Michael Ittmann, Matthew Robertson, Jin Wang, Darlene Skapura, Christel Davis, Erik Ehli, Matthew Freedman, Cristian Coarfa, Bert O'Malley, Nicholas Mitsiades
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1565.
https://doi.org/10.1158/1538-7445.AM2019-1565
Published: 01 July 2019
View articletitled, Abstract 1565: A novel therapeutic target in lethal prostate cancer in African American males
Journal Articles

Abstract 3467: Growth factor receptor trafficking in neuroblastoma differentiation

Jacqueline Lesperance, Divya Subramonian, Sarah Woodfield, Rongjun Guo, Andrew Bean, Dolores Lopez-Terrada, Michael Ittmann, Sara Hakim, Peter E. Zage
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3467.
https://doi.org/10.1158/1538-7445.AM2018-3467
Published: 01 July 2018
View articletitled, Abstract 3467: Growth factor receptor trafficking in neuroblastoma differentiation
Journal Articles

RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression

Yongquan Wang, Jianghua Wang, Li Zhang, Omer Faruk Karatas, Longjiang Shao, Yiqun Zhang, Patricia Castro, Chad J. Creighton, Michael Ittmann
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4247–4257.
https://doi.org/10.1158/0008-5472.CAN-17-0669
Published: 14 August 2017
View articletitled, RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression
Open the PDF for RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression in another window
Includes: Supplementary data
Journal Articles

Abstract 1577: GRK3 is a direct target of ADT-induced CREB1 activation and it promotes neuroendocrine differentiation of prostate cancer cells

Dayong Zheng, Mohit Hulsurkar, Meixiang Sang, Songlin Zhang, Jianming Xu, Martin Gleave, Michael Ittmann, Wenliang Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1577.
https://doi.org/10.1158/1538-7445.AM2017-1577
Published: 01 July 2017
View articletitled, Abstract 1577: GRK3 is a direct target of ADT-induced CREB1 activation and it promotes neuroendocrine differentiation of prostate cancer cells
Journal Articles

MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer

Li Zhang, Jianghua Wang, Yongquan Wang, Yiqun Zhang, Patricia Castro, Longjiang Shao, Arun Sreekumar, Nagireddy Putluri, Nilanjan Guha, Saligrama Deepak, Arunkumar Padmanaban, Chad J. Creighton, Michael Ittmann
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6290–6298.
https://doi.org/10.1158/0008-5472.CAN-16-0087
Published: 31 October 2016
View articletitled, MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer
Open the PDF for MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1174: AZD4547 and AZD5363 synergistically inhibit prostate cancer progression by modulating MAPK and AKT activation

Shu Feng, Michael Ittmann
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1174.
https://doi.org/10.1158/1538-7445.AM2016-1174
Published: 15 July 2016
View articletitled, Abstract 1174: AZD4547 and AZD5363 synergistically inhibit prostate cancer progression by modulating MAPK and AKT activation
Journal Articles

Abstract 1056: Inhibition of hexose monophosphate pathway promotes castration resistant prostate cancer

Akash K. Kaushik, Ali Shojaie, Katrin Panzitt, Rajni Sonavane, Harene Venghatakrishnan, Mohan Manikkam, Alexander Zaslavsky, Vasanta Putluri, Vihas Vasu, Yiqing Zhang, Ayesha Khan, Stacy Lloyd, Adam Szafran, Subhamoy Dasgupta, David Bader, Fabio Stossi, Hangwen Li, Susmita Samanta, Xuhong Cao, Efrosini Tsouko, Shixia Huang, Daniel Frigo, Lawrence Chan, Dean Edwards, Benny Kaipparettu, Nicholas Mitsiades, Nancy Weigel, Michael Mancini, Michael Ittmann, Arul Chinnaiyan, Nagireddy Putluri, Ganesh Palapattu, George Michailidis, Arun Sreekumar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1056.
https://doi.org/10.1158/1538-7445.AM2016-1056
Published: 15 July 2016
View articletitled, Abstract 1056: Inhibition of hexose monophosphate pathway promotes castration resistant prostate cancer
Journal Articles

Abstract 4591: Differential expression of tight junction polarity genes in human colon cancer

Kathryn E. Royse, Liang Chen, Jocelyn Uriostegui, Michael Ittmann, David Y. Graham, Hashem El-Serag, Li Jiao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4591.
https://doi.org/10.1158/1538-7445.AM2015-4591
Published: 01 August 2015
View articletitled, Abstract 4591: Differential expression of tight junction polarity genes in human colon cancer
Journal Articles

Abstract 3918: Synergistic targeting of fibroblast growth factor receptor and AKT pathways significantly inhibits prostate cancer progression

Shu Feng, Michael Ittmann
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3918.
https://doi.org/10.1158/1538-7445.AM2015-3918
Published: 01 August 2015
View articletitled, Abstract 3918: Synergistic targeting of fibroblast growth factor receptor and AKT pathways significantly inhibits prostate cancer progression
Journal Articles

Abstract 4132: Expression of pattern recognition receptor genes and survival in colorectal adenocarcinoma

Liang Chen, David Berger, Michael Ittmann, Hashem B. El-Serag, Courtney J. Balentine, David Y. Graham, Peter A. Richardson, Margaret R. Spitz, Susan G. Hilsenbeck, Rolando Rumbaut, Zhigang Duan, Donna L. White, Li Jiao
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4132.
https://doi.org/10.1158/1538-7445.AM2014-4132
Published: 01 October 2014
View articletitled, Abstract 4132: Expression of pattern recognition receptor genes and survival in colorectal adenocarcinoma
Journal Articles

Abstract 3446: Fibroblast growth factor 23 promotes prostate cancer cell proliferation and invasiveness in vitro

Shu Feng, Michael Ittmann
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3446.
https://doi.org/10.1158/1538-7445.AM2014-3446
Published: 01 October 2014
View articletitled, Abstract 3446: Fibroblast growth factor 23 promotes prostate cancer cell proliferation and invasiveness in vitro
Journal Articles

The Steroid Receptor Coactivator-3 Is Required for the Development of Castration-Resistant Prostate Cancer

Jean C-Y. Tien, Zhaoliang Liu, Lan Liao, Fen Wang, Yixiang Xu, Ye-Lin Wu, Niya Zhou, Michael Ittmann, Jianming Xu
Journal: Cancer Research
Cancer Res (2013) 73 (13): 3997–4008.
https://doi.org/10.1158/0008-5472.CAN-12-3929
Published: 30 June 2013
View articletitled, The Steroid Receptor Coactivator-3 Is Required for the Development of Castration-Resistant Prostate Cancer
Open the PDF for The Steroid Receptor Coactivator-3 Is Required for the Development of Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract C64: Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation

Nahyun Choi, Boyu Zhang, Li Zhang, Michael Ittmann, Li Xin
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): C64.
https://doi.org/10.1158/1538-7445.PRCA2012-C64
Published: 09 May 2013
View articletitled, Abstract C64: Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation
Journal Articles

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee

Michael Ittmann, Jiaoti Huang, Enrico Radaelli, Philip Martin, Sabina Signoretti, Ruth Sullivan, Brian W. Simons, Jerrold M. Ward, Brian D. Robinson, Gerald C. Chu, Massimo Loda, George Thomas, Alexander Borowsky, Robert D. Cardiff
Journal: Cancer Research
Cancer Res (2013) 73 (9): 2718–2736.
https://doi.org/10.1158/0008-5472.CAN-12-4213
Published: 30 April 2013
View articletitled, Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Open the PDF for Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee in another window
Includes: Supplementary data