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Michael Goggins
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Journal Articles

Abstract 885: A risk prediction tool for individuals with a family history of breast, ovarian, or pancreatic cancer: BRCAPANCPRO

Amanda L. Blackford, Erica J. Childs, Nancy Porter, Gloria Petersen, Kari Rabe, Steven Gallinger, Ayelet Borgida, Sapna Syngal, Ann Schwartz, Michele Cote, Ralph Hruban, Michael Goggins, Alison P. Klein, Giovanni Parmigiani
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 885.
https://doi.org/10.1158/1538-7445.AM2021-885
Published: 01 July 2021
View article titled, Abstract 885: A risk prediction tool for individuals with a family history of breast, ovarian, or pancreatic cancer: BRCAPANCPRO
Journal Articles

Abstract 30: Impact of race, sex and age on the risk of pancreatic cancer in new onset diabetics in real-world data

Nancy R. Porter, Elham Afghani, Bryan Lau, Michael Goggins, Alison P. Klein
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 30.
https://doi.org/10.1158/1538-7445.AM2021-30
Published: 01 July 2021
View article titled, Abstract 30: Impact of race, sex and age on the risk of pancreatic cancer in new onset diabetics in real-world data
Journal Articles

Abstract PR12: The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice

Dannielle Engle, Herve Tiriac, Keith Rivera, Arnaud Pommier, Sean Whalen, Tobiloba Oni, Brinda Alagesan, Eun Lee, Melissa Yao, Matthew Lucito, Benjamin Spielman, Kenneth Yu, Robert Grutzmann, Daniela Aust, Phyllis Gimotty, Katherine Pollard, Ralph Hruban, Michael Goggins, Christian Pilarsky, Young Park, Darryl Pappin, Michael A. Hollingsworth, David Tuveson
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): PR12.
https://doi.org/10.1158/1538-7445.PANCA19-PR12
Published: 13 December 2019
View article titled, Abstract PR12: The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice
Journal Articles

Abstract 2509: High-resolution 1H human plasma profiling of pancreatic ductal adenocarcinoma

Santosh K. Bharti, Michael Goggins, Zaver M. Bhujwalla
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2509.
https://doi.org/10.1158/1538-7445.AM2017-2509
Published: 01 July 2017
View article titled, Abstract 2509: High-resolution <sup>1</sup>H &lt;MRS&gt; human plasma profiling of pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1378: Generating quality control reference standards to evaluate ultrasensitive variant detection

Marija Debeljak, Lisa Haley, Derek A. Anderson, Emily M. Adams, Masaya Suenaga, Katie Beierl, Ming-Tseh Lin, Michael Goggins, Christopher D. Gocke, James R. Eshleman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1378.
https://doi.org/10.1158/1538-7445.AM2016-1378
Published: 15 July 2016
View article titled, Abstract 1378: Generating quality control reference standards to evaluate ultrasensitive variant detection
Journal Articles

p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia

Audrey M. Hendley, Yue J. Wang, Kishore Polireddy, Janivette Alsina, Ishrat Ahmed, Kelly J. Lafaro, Hao Zhang, Nilotpal Roy, Samuel G. Savidge, Yanna Cao, Matthias Hebrok, Anirban Maitra, Albert B. Reynolds, Michael Goggins, Mamoun Younes, Christine A. Iacobuzio-Donahue, Steven D. Leach, Jennifer M. Bailey
Journal: Cancer Research
Cancer Res (2016) 76 (11): 3351–3363.
https://doi.org/10.1158/0008-5472.CAN-15-2268
Published: 31 May 2016
View article titled, p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia
Open the PDF for p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia in another window
Includes: Supplementary data
Journal Articles

Abstract 4186: p120 catenin: A novel regulator of epithelial cell delamination in early Kras-driven pancreatic cancer

Audrey M. Hendley, Yue J. Wang, Janivette Alsina, Ishrat Ahmed, Hao Zhang, Samuel Savidge, Hao Ho, Albert Reynolds, Anirban Maitra, Michael Goggins, Christine Iacobuzio-Donahue, Steven D. Leach, Jennifer M. Bailey
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4186.
https://doi.org/10.1158/1538-7445.AM2015-4186
Published: 01 August 2015
View article titled, Abstract 4186: p120 catenin: A novel regulator of epithelial cell delamination in early Kras-driven pancreatic cancer
Journal Articles

Abstract 2183: Expression patterns in pancreatic intraepithelial neoplasms

Michael Ayars, Eileen O'Sullivan, Michael Goggins
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2183.
https://doi.org/10.1158/1538-7445.AM2015-2183
Published: 01 August 2015
View article titled, Abstract 2183: Expression patterns in pancreatic intraepithelial neoplasms
Journal Articles

The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?

Anne Marie Lennon, Christopher L. Wolfgang, Marcia Irene Canto, Alison P. Klein, Joseph M. Herman, Michael Goggins, Elliot K. Fishman, Ihab Kamel, Matthew J. Weiss, Luis A. Diaz, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Ralph H. Hruban
Journal: Cancer Research
Cancer Res (2014) 74 (13): 3381–3389.
https://doi.org/10.1158/0008-5472.CAN-14-0734
Published: 30 June 2014
View article titled, The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?
Open the PDF for The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia? in another window
Journal Articles

Abstract B14: Epigenetic silencing of DAZ-interacting protein 1 in pancreatic ductal adenocarcinoma.

Eileen O'Sullivan, Noriyuki Omura, Michael Goggins
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B14.
https://doi.org/10.1158/1538-7445.PANCA2012-B14
Published: 03 April 2014
View article titled, Abstract B14: Epigenetic silencing of DAZ-interacting protein 1 in pancreatic ductal adenocarcinoma.
Journal Articles

Abstract 4006: Smad6 upregulation provides an alternative mechanism for BMP inactivation in SMAD4 wild type pancreatic cancers.

Jacqueline A. Brosnan, Richard Morgan, Catherine M. White, Seung-Mo Hong, Shinichi Yachida, Michael Goggins, Barish Edil, Christine A. Iacobuzio-Donahue
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4006.
https://doi.org/10.1158/1538-7445.AM2013-4006
Published: 15 April 2013
View article titled, Abstract 4006: Smad6 upregulation provides an alternative mechanism for BMP inactivation in SMAD4 wild type pancreatic cancers.
Journal Articles

Abstract 2174: MLL3 act as a tumor suppressor gene in pancreatic cancer

Sonal Gupta, Radha Mukherjee, Marco dal Molin, Michael Goggins, Sachin Hebbar, Anirban Maitra
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2174.
https://doi.org/10.1158/1538-7445.AM2012-2174
Published: 15 April 2012
View article titled, Abstract 2174: MLL3 act as a tumor suppressor gene in pancreatic cancer
Journal Articles

Abstract 2628: Genome-wide sequencing identifies ATM as a pancreatic cancer susceptibility gene

Nicholas J. Roberts, Yuchen Jiao, Jun Yu, Levy Kopelovich, Gloria M. Petersen, Melissa Bondy, Steven Gallinger, Ann G. Schwartz, Sapna Syngal, Michele L. Cote, Jennifer Axilbund, Richard Schulick, Syed Z. Ali, James R. Eshleman, Victor Velculescu, Michael Goggins, Bert Vogelstein, Nikolas Papadopoulous, Ralph H. Hruban, Kenneth W. Kinzler, Alison P. Klein
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2628.
https://doi.org/10.1158/1538-7445.AM2012-2628
Published: 15 April 2012
View article titled, Abstract 2628: Genome-wide sequencing identifies <em>ATM</em> as a pancreatic cancer susceptibility gene
Journal Articles

Pancreatic Cancers Epigenetically Silence SIP1 and Hypomethylate and Overexpress miR-200a/200b in Association with Elevated Circulating miR-200a and miR-200b Levels

Ang Li, Noriyuki Omura, Seung-Mo Hong, Audrey Vincent, Kimberly Walter, Margaret Griffith, Michael Borges, Michael Goggins
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5226–5237.
https://doi.org/10.1158/0008-5472.CAN-09-4227
Published: 30 June 2010
View article titled, Pancreatic Cancers Epigenetically Silence <em>SIP1</em> and Hypomethylate and Overexpress <em>miR-200a/200b</em> in Association with Elevated Circulating <em>miR-200a</em> and <em>miR-200b</em> Levels
Open the PDF for Pancreatic Cancers Epigenetically Silence <em>SIP1</em> and Hypomethylate and Overexpress <em>miR-200a/200b</em> in Association with Elevated Circulating <em>miR-200a</em> and <em>miR-200b</em> Levels in another window
Includes: Supplementary data
Journal Articles

Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling

Georg Feldmann, Anjali Mishra, Seung-Mo Hong, Savita Bisht, Christopher J. Strock, Douglas W. Ball, Michael Goggins, Anirban Maitra, Barry D. Nelkin
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4460–4469.
https://doi.org/10.1158/0008-5472.CAN-09-1107
Published: 01 June 2010
View article titled, Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling
Open the PDF for Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 4173: In vivo and in vitro propagation of Intraductal Papillay Mucinous Neoplasms

Hirohiko Kamiyama, Mihoko Kamiyama, Seung-Mo Hong, Collins Karikari, Ming-Tseh Lin, Margaret Griffith, Angela Young, Alexis Kirby, Michael Borges, Conrad Lubek, Masamichi Mizuma, Georg Feldman, Chanjuan Shi, Hong Liang, Michael Goggins, Anirban Maitra, Ralph Hruban, James Eshleman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4173.
https://doi.org/10.1158/1538-7445.AM10-4173
Published: 15 April 2010
View article titled, Abstract 4173: <em>In vivo and in vitro propagation of Intraductal Papillay Mucinous Neoplasms</em>
Journal Articles

Abstract 4094: Pancreatic cancers epigenetically silence ZFHX1B, hypomethylate and overexpress miR-200a/−200b, in association with elevated circulating miR-200a and miR-200b levels

Ang Li, Noriyuki Omura, Seung-Mo Hong, Audrey Vincent, Kimberly Walter, Margaret Griffith, Michael Borges, Michael Goggins
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4094.
https://doi.org/10.1158/1538-7445.AM10-4094
Published: 15 April 2010
View article titled, Abstract 4094: Pancreatic cancers epigenetically silence <em>ZFHX1B,</em> hypomethylate and overexpress miR-200a/−200b, in association with elevated circulating miR-200a and miR-200b levels
Journal Articles

Abstract #5156: Quantitative detection of methylation in pancreatic cancer by multiplex GeXP MSP

Ang Li, Noriyuki Omura, Michael Borges, Michael Goggins
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5156.
Published: 01 May 2009
View article titled, Abstract #5156: Quantitative detection of methylation in pancreatic cancer by multiplex GeXP MSP
Journal Articles

Abstract #2282: Ten new familial pancreatic cancer cell lines

Hirohiko Kamiyama, Ming-Tseh Lin, Mihoko Kamiyama, Li Hua, Collins Karikari, Baojin Fu, Alison Klein, Michael Goggins, Ralph Hruban, Anirban Maitra, Christine Iacobuzio-Donahue, James Eshleman
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2282.
Published: 01 May 2009
View article titled, Abstract #2282: Ten new familial pancreatic cancer cell lines
Journal Articles

Abstract #5410: Early detection of pancreatic carcinoma

David Gold, David Modrak, Guy Newsome, Zarir Karanjawala, Ralph Hruban, Michael Goggins, David Goldenberg
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5410.
Published: 01 May 2009
View article titled, Abstract #5410: Early detection of pancreatic carcinoma