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Michael E. Berens
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Journal Articles

Abstract 2959: Signatures of therapy-induced senescence in glioblastoma-derived extracellular vesicles

Valerie DeLuca, Priya Digumarti, Krystine Garcia-Mansfield, Patrick Pirrotte, Michael E. Berens
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2959.
https://doi.org/10.1158/1538-7445.AM2024-2959
Published: 22 March 2024
View articletitled, Abstract 2959: Signatures of therapy-induced senescence in glioblastoma-derived extracellular vesicles
Journal Articles

Abstract 2130: Glioblastoma-derived extracellular vesicle cargo as a reporter of drug delivery and effect

Valerie DeLuca, Nanyun Tang, Nathaniel Hansen, Anjali Raju, Charles Shaffer, Yue Hao, Terry C. Burns, Jann N. Sarkaria, Ian Parney, Patrick Pirrotte, Kendall Van Keuren-Jensen, Michael E. Berens
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2130.
https://doi.org/10.1158/1538-7445.AM2024-2130
Published: 22 March 2024
View articletitled, Abstract 2130: Glioblastoma-derived extracellular vesicle cargo as a reporter of drug delivery and effect
Journal Articles

Abstract 2788: Extracellular vesicles as a pharmacodynamic reporter in glioblastoma

Valerie DeLuca, Nanyun Tang, Yue Hao, Anjali Raju, Charles Shaffer, Cecile Riviere-Cazaux, Terry C. Burns, Jann Sarkaria, Ian Parney, Patrick Pirrotte, Kendall Van Keuren-Jensen, Michael E. Berens
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2788.
https://doi.org/10.1158/1538-7445.AM2023-2788
Published: 04 April 2023
View articletitled, Abstract 2788: Extracellular vesicles as a pharmacodynamic reporter in glioblastoma
Journal Articles

Abstract 4794: Deciphering tumor recurrence post-therapy: Interactions between the tumor microenvironment and therapy-induced senescent glioblastoma

Valerie DeLuca, Priya Digumarti, Michael E. Berens
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4794.
https://doi.org/10.1158/1538-7445.AM2023-4794
Published: 04 April 2023
View articletitled, Abstract 4794: Deciphering tumor recurrence post-therapy: Interactions between the tumor microenvironment and therapy-induced senescent glioblastoma
Journal Articles

Abstract 4102: Vulnerability signature guided glioblastoma umbrella trial

Michael E. Berens, Sen Peng, Matthew Lee, Nanyun Tang, Manmeet S. Ahluwalia, Ekokobe Fonkem, Karen L. Fink, Jeffrey Raizer, Christopher Walker, Harshil Dhruv
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4102.
https://doi.org/10.1158/1538-7445.AM2022-4102
Published: 15 June 2022
View articletitled, Abstract 4102: Vulnerability signature guided glioblastoma umbrella trial
Journal Articles

Abstract 3248: Acquired resistance to targeted inhibitors in EGFR-driven glioblastoma: Identification of dual kinase targets

Abigail K. Shelton, Erin Smithberger, Madison Butler, Allie Stamper, Ryan E. Bash, Steve P. Angus, Michael P. East, Gary L. Johnson, Michael E. Berens, Frank B. Furnari, Ryan Miller
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3248.
https://doi.org/10.1158/1538-7445.AM2022-3248
Published: 15 June 2022
View articletitled, Abstract 3248: Acquired resistance to targeted inhibitors in EGFR-driven glioblastoma: Identification of dual kinase targets
Journal Articles

Abstract 1857: Glioblastoma growth is suppressed dual inhibition of EGFR and CDK6 kinases

Erin Smithberger, Abigail K. Shelton, Ryan E. Bash, Madison K. Butler, Alex R. Flores, Allie Stamper, Steven P. Angus, Michael P. East, Gary L. Johnson, Michael E. Berens, Frank B. Furnari, Ryan Miller
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1857.
https://doi.org/10.1158/1538-7445.AM2022-1857
Published: 15 June 2022
View articletitled, Abstract 1857: Glioblastoma growth is suppressed dual inhibition of EGFR and CDK6 kinases
Journal Articles

Abstract 180: Identifying signatures of vulnerability through machine learning in an umbrella trial for glioblastoma

Matthew Eric Lee, Nanyun Tang, Manmeet Ahluwalia, Ekokobe Fonkem, Karen Fink, Harshil Dhurv, Harshil Dhurv, Michael E. Berens, Sen Peng
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 180.
https://doi.org/10.1158/1538-7445.AM2021-180
Published: 01 July 2021
View articletitled, Abstract 180: Identifying signatures of vulnerability through machine learning in an umbrella trial for glioblastoma
Journal Articles

Abstract 318: Multi-omics to edge into precision medicine for DIPG

Nanyun Tang, Kristin Leskoske, Krystine Garcia-Mansfield, Ritin Sharma, Hannah Tolson, Patrick Pirrotte, Michael E. Berens
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 318.
https://doi.org/10.1158/1538-7445.AM2021-318
Published: 01 July 2021
View articletitled, Abstract 318: Multi-omics to edge into precision medicine for DIPG
Journal Articles

Abstract 2984: Building an in vitro blood brain barrier model to test the influence of tight junction gene alleles on disruption by focused ultrasound to treat brain tumors

Jayashree Iyer, Adam Akkad, Nanyun Tang, Michael E. Berens, Frederic Zenhausern, Jian Gu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2984.
https://doi.org/10.1158/1538-7445.AM2021-2984
Published: 01 July 2021
View articletitled, Abstract 2984: Building an in vitro blood brain barrier model to test the influence of tight junction gene alleles on disruption by focused ultrasound to treat brain tumors
Journal Articles

Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma

Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, James Jensen, Alexandra Garancher, Lianne Q. Chau, Silvia K. Tacheva-Grigorova, Sameerah Wahab, Yoko T. Udaka, Darren Finlay, Huriye Seker-Cin, Brendan Reardon, Susanne Gröbner, Jonathan Serrano, Jonas Ecker, Lin Qi, Mari Kogiso, Yuchen Du, Patricia A. Baxter, Jacob J. Henderson, Michael E. Berens, Kristiina Vuori, Till Milde, Yoon-Jae Cho, Xiao-Nan Li, James M. Olson, Iris Reyes, Matija Snuderl, Terence C. Wong, David P. Dimmock, Shareef A. Nahas, Denise Malicki, John R. Crawford, Michael L. Levy, Eliezer M. Van Allen, Stefan M. Pfister, Pablo Tamayo, Marcel Kool, Jill P. Mesirov, Robert J. Wechsler-Reya
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5393–5407.
https://doi.org/10.1158/0008-5472.CAN-20-1655
Published: 02 December 2020
View articletitled, Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma
Open the PDF for Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5822: Targeting an immortalization mutation to control glioblastoma

Jayashree S. Iyer, Nanyun Tang, Shayesteh R. Ferdosi, Vijay Gokhale, Laurence H. Hurley, Harshil D. Dhruv, Michael E. Berens
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5822.
https://doi.org/10.1158/1538-7445.AM2020-5822
Published: 15 August 2020
View articletitled, Abstract 5822: Targeting an immortalization mutation to control glioblastoma
Journal Articles

Abstract 3681: Selective vulnerability of GBM PDX to a panel of EGFR tyrosine kinase inhibitors

Nanyun Tang, George Reid, C Ryan Miller, Michael E. Berens
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3681.
https://doi.org/10.1158/1538-7445.AM2020-3681
Published: 15 August 2020
View articletitled, Abstract 3681: Selective vulnerability of GBM PDX to a panel of EGFR tyrosine kinase inhibitors
Journal Articles

Abstract 3019: Dynamic kinome profiling of EGFRvIII-driven murine astrocyte models of glioblastoma reveals targets for dual kinase inhibitor therapy

Erin Smithberger, Abigail K. Shelton, Madison K. Butler, Alex R. Flores, Ryan E. Bash, Steven P. Angus, Noah Sciaky, Harshil D. Dhruv, Gary L. Johnson, Michael E. Berens, Frank B. Furnari, C. Ryan Miller
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3019.
https://doi.org/10.1158/1538-7445.AM2019-3019
Published: 01 July 2019
View articletitled, Abstract 3019: Dynamic kinome profiling of EGFRvIII-driven murine astrocyte models of glioblastoma reveals targets for dual kinase inhibitor therapy
Journal Articles

Abstract 331: Dynamic kinome targeting reveals kinases involved in acquired resistance to tyrosine kinase inhibitors in EGFR-driven glioblastomas

Abby Shelton, Erin Smithberger, Madison Butler, Alex Flores, Ryan Bash, Steve Angus, Noah Sciaky, Harshil Dhruv, Gary L. Johnson, Michael E. Berens, Frank Furnari, C. Ryan Miller
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 331.
https://doi.org/10.1158/1538-7445.AM2019-331
Published: 01 July 2019
View articletitled, Abstract 331: Dynamic kinome targeting reveals kinases involved in acquired resistance to tyrosine kinase inhibitors in EGFR-driven glioblastomas
Journal Articles

Abstract 881: Identifying the context of vulnerability to MLN4924 in glioblastoma (GBM)

Leena Chaudhuri, Rita L. Bybee, Lauren K. Hartman, Sen Peng, Darren Finlay, Kristiina Vuori, Michael E. Berens, Harshil D. Dhruv
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 881.
https://doi.org/10.1158/1538-7445.AM2018-881
Published: 01 July 2018
View articletitled, Abstract 881: Identifying the context of vulnerability to MLN4924 in glioblastoma (GBM)
Journal Articles

Abstract 2372: Kinome profiling of non-germline, genetically engineered mouse models of glioblastoma driven by Cdkn2a, Egfr, and/or Pten mutations reveals genotype-dependent kinase targets

Erin Smithberger, Alex R. Flores, Madison K. Butler, Harshil D. Dhruv, Gary L. Johnson, Michael E. Berens, Frank B. Furnari, C. Ryan Miller
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2372.
https://doi.org/10.1158/1538-7445.AM2018-2372
Published: 01 July 2018
View articletitled, Abstract 2372: Kinome profiling of non-germline, genetically engineered mouse models of glioblastoma driven by Cdkn2a, Egfr, and/or Pten mutations reveals genotype-dependent kinase targets
Journal Articles

Abstract 3039: Role of IDH mutation status on molecular and spatial heterogeneity in glial tumors across progression and recurrence

Michael E. Berens, Jill S. Barnholtz-Sloan, Miribella Rusu, John Graf, Anup Sood, Sanghee Cho, Maria Zavodszky, Sara Byron, Rebecca Halperin, Yi Fritz, Seungchan Kim, Fiona Ginty
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3039.
https://doi.org/10.1158/1538-7445.AM2018-3039
Published: 01 July 2018
View articletitled, Abstract 3039: Role of IDH mutation status on molecular and spatial heterogeneity in glial tumors across progression and recurrence
Journal Articles

Abstract 3589: A systematic approach toward gene annotation of the hallmarks of cancer

Jeff Kiefer, Sara Nasser, John Graf, Chinnappa Kodira, Fiona Ginty, Lee Newberg, Anup Sood, Michael E. Berens
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3589.
https://doi.org/10.1158/1538-7445.AM2017-3589
Published: 01 July 2017
View articletitled, Abstract 3589: A systematic approach toward gene annotation of the hallmarks of cancer
Journal Articles

Abstract 1329: Intravenous delivery of Erlotinib-loaded PLA-PEG nanoparticles for treatment of GB

Lauren K. Hartman, Harshil D. Dhruv, Kyle T. Householder, Jeffrey E. Roth, Allison N. Schorzman, William Zamboni, Rachel Sirianni, Michael E. Berens
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1329.
https://doi.org/10.1158/1538-7445.AM2016-1329
Published: 15 July 2016
View articletitled, Abstract 1329: Intravenous delivery of Erlotinib-loaded PLA-PEG nanoparticles for treatment of GB