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Journal Articles

Abstract A058 Response of neuroblastoma patient-derived xenografts to cyclophosphamide + topotecan enables identification of gene expression patterns associated with drug resistance

Nighat Noureen, Harry May, In-Hyoung Yang, Kristyn McCoy, Jonas Nance, Diana Ixlamati-Nava, Meredith S Irwin, Michael D. Hogarty, Charles P. Reynolds, Min H. Kang

Cancer Res (2024) 84 (17_Supplement): A058.

https://doi.org/10.1158/1538-7445.PEDIATRIC24-A058

Published: 05 September 2024

View article titled, Abstract A058 Response of neuroblastoma patient-derived xenografts to cyclophosphamide + topotecan enables identification of gene expression patterns associated with drug resistance

Journal Articles

Abstract B062: VCAN+ macrophages promote neuroblastoma cell growth, migration, and adrenergic to mesenchymal transition via the HB-EGF/ERBB signaling axis

Rumeysa Biyik-Sit, Wenbao Yu, Chia-Hui Chen, Anusha Thadi, Minxing Pang, Liron D. Grossmann, Tasleema Patel, Daniel Martinez, Lea F. Surrey, Michael D. Hogarty, Kathrin Bernt, Nancy Zhang, John M. Maris, Kai Tan

Cancer Res (2024) 84 (17_Supplement): B062.

https://doi.org/10.1158/1538-7445.PEDIATRIC24-B062

Published: 05 September 2024

View article titled, Abstract B062: VCAN+ macrophages promote neuroblastoma cell growth, migration, and adrenergic to mesenchymal transition via the HB-EGF/ERBB signaling axis

Journal Articles

Abstract 5122: Modulating anti-GD2 immunotherapy via dual DFMO and TGF-β inhibition in neuroblastoma

Om H. Gandhi, Christina S. Turn, Kangning Liu, Annette T. Vu, Hamid Bassiri, Michael D. Hogarty

Cancer Res (2024) 84 (6_Supplement): 5122.

https://doi.org/10.1158/1538-7445.AM2024-5122

Published: 22 March 2024

View article titled, Abstract 5122: Modulating anti-GD2 immunotherapy via dual DFMO and TGF-β inhibition in neuroblastoma

Journal Articles

Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma

Maged Zeineldin, Sara M. Federico, Lyra Griffith, Jongyre Jeon, Xiang Chen, John Easton, Jianrong Wu, Shenghua Mao, Yanling Liu, Arlene Naranjo, Alberto S. Pappo, Michael D. Hogarty, Michael A. Dyer

Cancer Res (2018) 78 (19_Supplement): PR11.

https://doi.org/10.1158/1538-7445.PEDCA17-PR11

Published: 01 October 2018

View article titled, Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma

Journal Articles

Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Maged Zeineldin, Sara Federico, Xiang Chen, Beisi Xu, Elizabeth Stewart, Arlene Naranjo, Michael D. Hogarty, Michael A. Dyer

Cancer Res (2018) 78 (19_Supplement): IA18.

https://doi.org/10.1158/1538-7445.PEDCA17-IA18

Published: 01 October 2018

View article titled, Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Journal Articles

Abstract 4137: Inhibition of protein synthesis with polyamine depletion in high-risk neuroblastoma

Andrea T. Flynn, Kangning Liu, Annette Vu, Michael D. Hogarty

Cancer Res (2018) 78 (13_Supplement): 4137.

https://doi.org/10.1158/1538-7445.AM2018-4137

Published: 01 July 2018

View article titled, Abstract 4137: Inhibition of protein synthesis with polyamine depletion in high-risk neuroblastoma

Journal Articles

Abstract 1201: Disrupted endoplasmic reticulum-mitochondria contacts promote multidrug resistance

Jorida Coku, Madison C. Pedrotty, David M. Booth, Sharon Kim, Annette Vu, C. Patrick Reynolds, György Hajnóczky, Michael D. Hogarty

Cancer Res (2017) 77 (13_Supplement): 1201.

https://doi.org/10.1158/1538-7445.AM2017-1201

Published: 01 July 2017

View article titled, Abstract 1201: Disrupted endoplasmic reticulum-mitochondria contacts promote multidrug resistance

Journal Articles

Abstract 1630: Modulation of the neuroblastoma microenvironment via polyamine blockade

Adriana D. Benavides, Annette Vu, Gabrielle M. Ferry, Michael D. Hogarty, Hamid Bassiri

Cancer Res (2017) 77 (13_Supplement): 1630.

https://doi.org/10.1158/1538-7445.AM2017-1630

Published: 01 July 2017

View article titled, Abstract 1630: Modulation of the neuroblastoma microenvironment via polyamine blockade

Journal Articles

Abstract 2459: Chemotherapy resistance in pediatric neuroblastoma is associated with reduced ER-mitochondria tethering

Jorida Coku, Elizabeth O. Scadden, Kangning Liu, Annette Vu, David M. Booth, Michelle Chen, Sharon Kim, C. Patrick Reynolds, György Hajnóczky, Michael D. Hogarty

Cancer Res (2016) 76 (14_Supplement): 2459.

https://doi.org/10.1158/1538-7445.AM2016-2459

Published: 15 July 2016

View article titled, Abstract 2459: Chemotherapy resistance in pediatric neuroblastoma is associated with reduced ER-mitochondria tethering

Journal Articles

Abstract 2980: Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

Cancer Res (2015) 75 (15_Supplement): 2980.

https://doi.org/10.1158/1538-7445.AM2015-2980

Published: 01 August 2015

View article titled, Abstract 2980: Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

Journal Articles

Abstract B56: Genomic background of neuroblastomas with intratumor heterogeneity of MYCN amplification

Inge M. Ambros, Clemens Brunner, Dominik Bogen, Gabriele Amann, Reza Abbasi, Barbara Gürtl-Lackner, Michael D. Hogarty, Tommy Martinsson, Martin Bilban, Ruth Ladenstein, Peter F. Ambros

Cancer Res (2014) 74 (20_Supplement): B56.

https://doi.org/10.1158/1538-7445.PEDCAN-B56

Published: 09 October 2014

View article titled, Abstract B56: Genomic background of neuroblastomas with intratumor heterogeneity of MYCN amplification

Journal Articles

Abstract B40: MYCN/MYC protein expression in high-MKI (Mitosis-Karyorrhexis Index) neuroblastomas: A report from the Children's Oncology Group

Larry L. Wang, Risa Teshiba, Lejian He, Arlene Naranjo, Wendy B. London, Julie M. Gastier-Foster, Robert C. Seeger, Susan L. Cohn, John M. Maris, Julie R. Park, Michael D. Hogarty, Hiroyuki Shimada

Cancer Res (2014) 74 (20_Supplement): B40.

https://doi.org/10.1158/1538-7445.PEDCAN-B40

Published: 09 October 2014

View article titled, Abstract B40: MYCN/MYC protein expression in high-MKI (Mitosis-Karyorrhexis Index) neuroblastomas: A report from the Children's Oncology Group

Journal Articles

Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma

Kelly C. Goldsmith, Michelle Gross, Susan Peirce, Dema Luyindula, Xueyuan Liu, Annette Vu, Michael Sliozberg, Rong Guo, Huaqing Zhao, C. Patrick Reynolds, Michael D. Hogarty

Cancer Res (2012) 72 (10): 2565–2577.

https://doi.org/10.1158/0008-5472.CAN-11-3603

Published: 14 May 2012

View article titled, Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma

Includes: Supplementary data

Journal Articles

Abstract 4848: A synthetic-lethal screen identifies novel Mcl1 regulators in neuroblastoma

Theodore Laetsch, Xueyuan Liu, Michael Sliozberg, Michael Vido, Annette Vu, Kelly Goldsmith, Michael D. Hogarty

Cancer Res (2012) 72 (8_Supplement): 4848.

https://doi.org/10.1158/1538-7445.AM2012-4848

Published: 15 April 2012

View article titled, Abstract 4848: A synthetic-lethal screen identifies novel Mcl1 regulators in neuroblastoma

Journal Articles

Abstract 926: Whole genome and transcriptome sequencing defines the spectrum of somatic changes in high-risk neuroblastoma

Cancer Res (2011) 71 (8_Supplement): 926.

https://doi.org/10.1158/1538-7445.AM2011-926

Published: 15 April 2011

View article titled, Abstract 926: Whole genome and transcriptome sequencing defines the spectrum of somatic changes in high-risk neuroblastoma

Journal Articles

Abstract 5249: Identification of genome-wide alternative splicing events in high-risk MYCN amplified neuroblastomas

Shahab Asgharzadeh, Lingyun Ji, Richard Sposto, Edward Attiyeh, Yue-Xian Tu, Michael Hadjidaniel, Michael D. Hogarty, Wendy B. London, Julie Gastier-Foster, Jun Wei, Xiang Guo, Daniela S. Gerhard, Malcolm A. Smith, Javed Khan, John M. Maris, Robert C. Seeger

Cancer Res (2010) 70 (8_Supplement): 5249.

https://doi.org/10.1158/1538-7445.AM10-5249

Published: 15 April 2010

View article titled, Abstract 5249: Identification of genome-wide alternative splicing events in high-risk MYCN amplified neuroblastomas

Journal Articles

Abstract 5252: BH3 profiling identifies apoptosis resistance heterogeneity in neuroblastoma and predicts in vivo potency of Bcl2 antagonists

Kelly C. Goldsmith, Michelle Gross, Xueyuan Liu, Susan K. Peirce, Chengyu Prince, Michael D. Hogarty

Cancer Res (2010) 70 (8_Supplement): 5252.

https://doi.org/10.1158/1538-7445.AM10-5252

Published: 15 April 2010

View article titled, Abstract 5252: BH3 profiling identifies apoptosis resistance heterogeneity in neuroblastoma and predicts in vivo potency of Bcl2 antagonists

Journal Articles

Abstract 5258: Genomic characterization and targeted resequencing of high-risk neuroblastoma (the neuroblastoma TARGET)

Edward F. Attiyeh, Michael D. Hogarty, Yaël P. Mossé, Sharon J. Diskin, Hakon Hakonarson, Shahab Asgharzadeh, Richard Sposto, Wendy B. London, Julie M. Gastier-Foster, Daniela S. Gerhard, Malcolm A. Smith, Jinghui Zhang, Javed Khan, Robert C. Seeger, John M. Maris

Cancer Res (2010) 70 (8_Supplement): 5258.

https://doi.org/10.1158/1538-7445.AM10-5258

Published: 15 April 2010

View article titled, Abstract 5258: Genomic characterization and targeted resequencing of high-risk neuroblastoma (the neuroblastoma TARGET)

Journal Articles

ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma

Cancer Res (2008) 68 (23): 9735–9745.

https://doi.org/10.1158/0008-5472.CAN-07-6866

Published: 01 December 2008

View article titled, ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma

Includes: Supplementary data

Journal Articles

Abstract 5832: Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target

Michelle Haber, Ngan Cheng, Janice Smith, Jayne Murray, Michael D. Hogarty, Wendy B London, Glenn M Marshall, Murray D. Norris

Cancer Res (2008) 68 (9_Supplement): 5832.

https://doi.org/10.1158/1538-7445.AM2008-5832

Published: 15 May 2008

View article titled, Abstract 5832: Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target

NARROW

Abstract A058 Response of neuroblastoma patient-derived xenografts to cyclophosphamide + topotecan enables identification of gene expression patterns associated with drug resistance

Abstract B062: VCAN+ macrophages promote neuroblastoma cell growth, migration, and adrenergic to mesenchymal transition via the HB-EGF/ERBB signaling axis

Abstract 5122: Modulating anti-GD2 immunotherapy via dual DFMO and TGF-β inhibition in neuroblastoma

Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma

Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Abstract 4137: Inhibition of protein synthesis with polyamine depletion in high-risk neuroblastoma

Abstract 1201: Disrupted endoplasmic reticulum-mitochondria contacts promote multidrug resistance

Abstract 1630: Modulation of the neuroblastoma microenvironment via polyamine blockade

Abstract 2459: Chemotherapy resistance in pediatric neuroblastoma is associated with reduced ER-mitochondria tethering

Abstract 2980: Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

Abstract B56: Genomic background of neuroblastomas with intratumor heterogeneity of MYCN amplification

Abstract B40: MYCN/MYC protein expression in high-MKI (Mitosis-Karyorrhexis Index) neuroblastomas: A report from the Children's Oncology Group

Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma

Abstract 4848: A synthetic-lethal screen identifies novel Mcl1 regulators in neuroblastoma

Abstract 926: Whole genome and transcriptome sequencing defines the spectrum of somatic changes in high-risk neuroblastoma

Abstract 5249: Identification of genome-wide alternative splicing events in high-risk MYCN amplified neuroblastomas

Abstract 5252: BH3 profiling identifies apoptosis resistance heterogeneity in neuroblastoma and predicts in vivo potency of Bcl2 antagonists

Abstract 5258: Genomic characterization and targeted resequencing of high-risk neuroblastoma (the neuroblastoma TARGET)

ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma

Abstract 5832: Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target

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