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Journal Articles

Abstract 3379: Adaptation of soft agar colony formation assays to identify agents which block proliferation of putative colon cancer stem cells

Michael C. Alley, Mark W. Burkett, Karen M. Hite, Susan D. Mertins, John E. Niederhuber, Robert H. Shoemaker

Cancer Res (2012) 72 (8_Supplement): 3379.

https://doi.org/10.1158/1538-7445.AM2012-3379

Published: 15 April 2012

View article titled, Abstract 3379: Adaptation of soft agar colony formation assays to identify agents which block proliferation of putative colon cancer stem cells

Journal Articles

Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts in vivo

Michael C. Alley, Melinda G. Hollingshead, Suzanne D. Borgel, Kevin Plater, Mark W. Burkett, Miriam R. Anver, Brandon R. Yen, Karen M. Hite, Dominic A. Scudiero, Anne Monks, Susan D. Mertins, Robert H. Shoemaker, John E. Niederhuber

Cancer Res (2011) 71 (8_Supplement): 5202.

https://doi.org/10.1158/1538-7445.AM2011-5202

Published: 15 April 2011

View article titled, Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts in vivo

Journal Articles

The histone deacetylase inhibitor FK228 can increase adenovirus transgene expression in human LOX IMVI melanoma xenografts

Merrill E. Goldsmith, Alian Aguila, Michael C. Alley, William R. Waud, Susan Bates, Tito Fojo

Cancer Res (2005) 65 (9_Supplement): 313.

Published: 01 May 2005

View article titled, The histone deacetylase inhibitor FK228 can increase adenovirus transgene expression in human LOX IMVI melanoma xenografts

Journal Articles

The novel inhibitor of heterotrimer G-protein signaling, BIM-46174, enhances the anticancer activity of cisplatin in human NSCLC lung tumor xenografts

Gregoire Prevost, Marie-Odile Lonchampt, Susan Holbeck, S. Attoub, Daniel W. Zaharevitz, Michael C. Alley, John J. Wright, Marie-Christine Brezak, Helene Couloumb, Ann Savola, Marion Huchet, Sophie Chaumeron, Q.-D. Nguyen, P. Forgez, Eric Ferrandis, Pierre Roubert, Christian Gespach, Philip G. Kasprzyk

Cancer Res (2005) 65 (9_Supplement): 158.

Published: 01 May 2005

View article titled, The novel inhibitor of heterotrimer G-protein signaling, BIM-46174, enhances the anticancer activity of cisplatin in human NSCLC lung tumor xenografts

Journal Articles

In vitro and in vivo evaluations of leptomycin analogs which exhibit potent and differential anticancer activities

Michael C. Alley, Melinda G. Hollingshead, Christine M. Pacula-Cox, John M. Venditti, Thomas G. McCloud, Rhone K. Akee, David J. Newman

Cancer Res (2005) 65 (9_Supplement): 149.

Published: 01 May 2005

View article titled, In vitro and in vivo evaluations of leptomycin analogs which exhibit potent and differential anticancer activities

Journal Articles

SJG-136 (NSC 694501), A Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 2: Efficacy Evaluations

Michael C. Alley, Melinda G. Hollingshead, Christine M. Pacula-Cox, William R. Waud, John A. Hartley, Philip W. Howard, Stephen J. Gregson, David E. Thurston, Edward A. Sausville

Cancer Res (2004) 64 (18): 6700–6706.

https://doi.org/10.1158/0008-5472.CAN-03-2942

Published: 16 September 2004

View article titled, SJG-136 (NSC 694501), A Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: <subtitle>Part 2: Efficacy Evaluations</subtitle>

Journal Articles

SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 1: Cellular Pharmacology, In vitro and Initial In vivo Antitumor Activity

John A. Hartley, Victoria J. Spanswick, Natalie Brooks, Peter H. Clingen, Peter J. McHugh, Daniel Hochhauser, R. Barbara Pedley, Lloyd R. Kelland, Michael C. Alley, Robert Schultz, Melinda G. Hollingshead, Karen M. Schweikart, Joseph E. Tomaszewski, Edward A. Sausville, Stephen J. Gregson, Philip W. Howard, David E Thurston

Cancer Res (2004) 64 (18): 6693–6699.

https://doi.org/10.1158/0008-5472.CAN-03-2941

Published: 16 September 2004

View article titled, SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: <subtitle>Part 1: Cellular Pharmacology, In vitro and Initial In vivo Antitumor Activity</subtitle>

Journal Articles

The histone deacetylase inhibitor FK228 can increase the levels of coxsackie-adenovirus receptor (CAR) in human xenografts in mouse model systems.

Merrill E. Goldsmith, Alian Aguila, Santhi J. Gollapalli, Michael C. Alley, William R. Waud, Susan Bates, Tito Fojo

Cancer Res (2004) 64 (7_Supplement): 540–541.

Published: 01 April 2004

View article titled, The histone deacetylase inhibitor FK228 can increase the levels of coxsackie-adenovirus receptor (CAR) in human xenografts in mouse model systems.

Journal Articles

In vitro and in vivo evaluations of artemisinin derivatives with potent and unique anticancer activities.

Michael C. Alley, Melinda G. Hollingshead, Sherman F. Stinson, Susan Holbeck, Shannon Decker, Mahmoud A. Elsohly, Ahmed M. Galal, Samir A. Ross, Edward A. Sausville

Cancer Res (2004) 64 (7_Supplement): 577.

Published: 01 April 2004

View article titled, In vitro and in vivo evaluations of artemisinin derivatives with potent and unique anticancer activities.

Journal Articles

2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a Novel Chloroethylnitrosourea Analogue with Enhanced Antitumor Activity against Human Glioma Xenografts

Daniela Marcantonio, Lawrence C. Panasci, Melinda G. Hollingshead, Michael C. Alley, Richard F. Camalier, Edward A. Sausville, Donald J. Dykes, Christopher A. Carter, Louis Malspeis

Cancer Res (1997) 57 (18): 3895–3898.

Published: 01 September 1997

View article titled, 2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a Novel Chloroethylnitrosourea Analogue with Enhanced Antitumor Activity against Human Glioma Xenografts

Journal Articles

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Angelika M. Burger, Gurmeet Kaur, Michael C. Alley, Jeffrey G. Supko, Louis Malspeis, Michael R. Grever, Edward A. Sausville

Cancer Res (1995) 55 (13): 2794–2799.

Published: 01 July 1995

View article titled, Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Journal Articles

Evidence for Prostanoid Biosynthesis as a Biochemical Feature of Certain Subclasses of Non-Small Cell Carcinomas of the Lung as Determined in Established Cell Lines Derived from Human Lung Tumors

Walter C. Hubbard, Michael C. Alley, Glenn N. Gray, Karen C. Green, Theodore L. McLemore, Michael R. Boyd

Cancer Res (1989) 49 (4): 826–832.

Published: 01 February 1989

View article titled, Evidence for Prostanoid Biosynthesis as a Biochemical Feature of Certain Subclasses of Non-Small Cell Carcinomas of the Lung as Determined in Established Cell Lines Derived from Human Lung Tumors

Journal Articles

Profiles of Prostaglandin Biosynthesis in Sixteen Established Cell Lines Derived from Human Lung, Colon, Prostate, and Ovarian Tumors

Walter C. Hubbard, Michael C. Alley, Theodore L. McLemore, Michael R. Boyd

Cancer Res (1988) 48 (17): 4770–4775.

Published: 01 September 1988

View article titled, Profiles of Prostaglandin Biosynthesis in Sixteen Established Cell Lines Derived from Human Lung, Colon, Prostate, and Ovarian Tumors

Journal Articles

In Vivo and in Vitro Enhanced Antitumor Effects by Pentoxifylline in Human Cancer Cells Treated with Thiotepa

Howard J. Fingert, Anthony T. Pu, Zuying Chen, Paul B. Googe, Michael C. Alley, Arthur B. Pardee

Cancer Res (1988) 48 (15): 4375–4381.

Published: 01 August 1988

View article titled, In Vivo and in Vitro Enhanced Antitumor Effects by Pentoxifylline in Human Cancer Cells Treated with Thiotepa

Journal Articles

Evidence for Thromboxane Biosynthesis in Established Cell Lines Derived from Human Lung Adenocarcinomas

Walter C. Hubbard, Michael C. Alley, Theodore L. McLemore, Michael R. Boyd

Cancer Res (1988) 48 (10): 2674–2677.

Published: 01 May 1988

View article titled, Evidence for Thromboxane Biosynthesis in Established Cell Lines Derived from Human Lung Adenocarcinomas

Journal Articles

Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay

Michael C. Alley, Dominic A. Scudiero, Anne Monks, Miriam L. Hursey, Maciej J. Czerwinski, Donald L. Fine, Betty J. Abbott, Joseph G. Mayo, Robert H. Shoemaker, Michael R. Boyd

Cancer Res (1988) 48 (3): 589–601.

Published: 01 February 1988

View article titled, Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay

Journal Articles

Novel Intrapulmonary Model for Orthotopic Propagation of Human Lung Cancers in Athymic Nude Mice

Theodore L. McLemore, Mark C. Liu, Penny C. Blacker, Marybelle Gregg, Michael C. Alley, Betty J. Abbott, Robert H. Shoemaker, Mark E. Bohlman, Charles C. Litterst, Walter C. Hubbard, Robert H. Brennan, James B. McMahon, Donald L. Fine, Joseph C. Eggleston, Joseph G. Mayo, Michael R. Boyd

Cancer Res (1987) 47 (19): 5132–5140.

Published: 01 October 1987

View article titled, Novel Intrapulmonary Model for Orthotopic Propagation of Human Lung Cancers in Athymic Nude Mice

NARROW

Abstract 3379: Adaptation of soft agar colony formation assays to identify agents which block proliferation of putative colon cancer stem cells

Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts in vivo

The histone deacetylase inhibitor FK228 can increase adenovirus transgene expression in human LOX IMVI melanoma xenografts

The novel inhibitor of heterotrimer G-protein signaling, BIM-46174, enhances the anticancer activity of cisplatin in human NSCLC lung tumor xenografts

In vitro and in vivo evaluations of leptomycin analogs which exhibit potent and differential anticancer activities

SJG-136 (NSC 694501), A Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 2: Efficacy Evaluations

SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 1: Cellular Pharmacology, In vitro and Initial In vivo Antitumor Activity

The histone deacetylase inhibitor FK228 can increase the levels of coxsackie-adenovirus receptor (CAR) in human xenografts in mouse model systems.

In vitro and in vivo evaluations of artemisinin derivatives with potent and unique anticancer activities.

2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a Novel Chloroethylnitrosourea Analogue with Enhanced Antitumor Activity against Human Glioma Xenografts

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Evidence for Prostanoid Biosynthesis as a Biochemical Feature of Certain Subclasses of Non-Small Cell Carcinomas of the Lung as Determined in Established Cell Lines Derived from Human Lung Tumors

Profiles of Prostaglandin Biosynthesis in Sixteen Established Cell Lines Derived from Human Lung, Colon, Prostate, and Ovarian Tumors

In Vivo and in Vitro Enhanced Antitumor Effects by Pentoxifylline in Human Cancer Cells Treated with Thiotepa

Evidence for Thromboxane Biosynthesis in Established Cell Lines Derived from Human Lung Adenocarcinomas

Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay

Novel Intrapulmonary Model for Orthotopic Propagation of Human Lung Cancers in Athymic Nude Mice

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