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Abstract 2786: Color-coded fluorescence-guided surgery in a patient-derived orthotopic xenograft (PDOX) nude mouse model of colon-cancer liver metastasis with ICG and a fluorescent antibody

Hiroto Nishino, Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Jun Yamamoto, Yoshihiko Tashiro, Robert M. Hoffman, Michael Bouvet

Cancer Res (2020) 80 (16_Supplement): 2786.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2786

Published: 15 August 2020

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Journal Articles

Abstract 1658: Anti-CEACAM binding protein for fluorescence visualization of primary colon cancer in patient-derived orthotopic xenograph mouse models

Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Verena Schmitt, Gunther Wennemuth, Alexej Schmidt, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet

Cancer Res (2020) 80 (16_Supplement): 1658.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1658

Published: 15 August 2020

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Journal Articles

Abstract 3733: Development of photoimmunotherapy for colon cancer in nude mice models

Hannah Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Sahar Razemjooie, Paul Yazaki, Robert Hoffman, Michael Bouvet

Cancer Res (2019) 79 (13_Supplement): 3733.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3733

Published: 01 July 2019

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Journal Articles

Abstract 3110: Heterokaryon formation and nuclear fusion of hybridizing cancer cells visualized in real time by color-coded imaging

Atsushi Suetsugu, Takuro Matsumoto, Kousuke Hasegawa, Miki Nakamura, Takahiro Kunisada, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman

Cancer Res (2018) 78 (13_Supplement): 3110.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3110

Published: 01 July 2018

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Journal Articles

Abstract 5900: Transforming growth factor-beta (TGF-β) inhibitor modulates cancer stroma in a pancreatic cancer orthotopic mouse model

Takashi Murakami, Yukihiko Hiroshima, Kentaro Miyake, Tasuku Kiyuna, Ho Kyoung Hwang, Kei Kawaguchi, Jonathan C. DeLong, Thinzer M. Lwin, Kentaro Igarashi, Ryusei Matsuyama, Ryutaro Mori, Takafumi Kumamoto, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman

Cancer Res (2017) 77 (13_Supplement): 5900.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5900

Published: 01 July 2017

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Journal Articles

Abstract 3729: Tumor-specific antibody labeling of pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model using a fluorescent humanized anti-CEA antibody

Thinzar Lwin, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet

Cancer Res (2017) 77 (13_Supplement): 3729.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3729

Published: 01 July 2017

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Journal Articles

Abstract 1872: Fluorescence-guided surgery in the tumor microenvironment in a syngeneic mouse model of EL-4 lymphoma

Kosuke Hasegawa, Atsushi Suetsugu, Miki Nakamura, Takuro Matsumoto, Takahiro Kunisada, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman

Cancer Res (2017) 77 (13_Supplement): 1872.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1872

Published: 01 July 2017

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Journal Articles

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection

Willemieke S. Tummers, Jason M. Warram, Kiranya E. Tipirneni, John Fengler, Paula Jacobs, Lalitha Shankar, Lori Henderson, Betsy Ballard, T. Joshua Pfefer, Brian W. Pogue, Jamey P. Weichert, Michael Bouvet, Jonathan Sorger, Christopher H. Contag, John V. Frangioni, Michael F. Tweedle, James P. Basilion, Sanjiv S. Gambhir, Eben L. Rosenthal

Cancer Res (2017) 77 (9): 2197–2206.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-3217

Published: 30 April 2017

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Includes: Supplementary data

Journal Articles

eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth

Jan Strnadel, Sunkyu Choi, Ken Fujimura, Huawei Wang, Wei Zhang, Meghan Wyse, Tracy Wright, Emilie Gross, Carlos Peinado, Hyun Woo Park, Jack Bui, Jonathan Kelber, Michael Bouvet, Kun-Liang Guan, Richard L. Klemke

Cancer Res (2017) 77 (8): 1997–2007.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-2594

Published: 13 April 2017

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Includes: Supplementary data

Journal Articles

Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Tasuku Kiyuna, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman

Cancer Res (2016) 76 (14_Supplement): 1408.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1408

Published: 15 July 2016

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Journal Articles

Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, MIchael Bouvet, Itaru Endo, Robert M. Hoffman

Cancer Res (2016) 76 (14_Supplement): 4220.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4220

Published: 15 July 2016

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Journal Articles

Abstract 4221: Imaging formation of the tumor microenvironment in orthotopic liver tumors in red fluorescent protein (RFP) transgenic nude mice

Atsushi Suetsugu, Yukihiko Hiroshima, Takuro Matsumoto, Kosuke Hasegawa, Miki Nakamura, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman

Cancer Res (2016) 76 (14_Supplement): 4221.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4221

Published: 15 July 2016

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Journal Articles

Abstract LB-263: Analysis of microenvironment effects on pancreatic cancer biomarker expression using a novel method for FFPE RNA extraction

Malachia Hoover, Yvess Adamian, Mark Brown, Ali A. Maawy, Robert Hoffman, Michael Bouvet, Robert Doebler, Jonathan A. Kelber

Cancer Res (2016) 76 (14_Supplement): LB-263.

DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-263

Published: 15 July 2016

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Journal Articles

Abstract 1456: Efficacy of photo-immunotherapy in combination with surgical resection on a pancreatic cancer patient derived orthotopic xenograft (PDOX)

Yukihiko Hiroshima, Ali Maawy, Takashi Murakami, Nzola De Magalhães, Daisuke Kawaguchi, Kenichi Matsuo, Kuniya Tanaka, Michael Bouvet, Robert M. Hoffman, Itaru Endo

Cancer Res (2015) 75 (15_Supplement): 1456.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1456

Published: 01 August 2015

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Journal Articles

Abstract 2019: Photoimmunotherapy with an anti-EGFR antibody conjugated to an IRDye700 results in extensive and rapid cell death in vitro and in vivo in human pancreatic cancer cell lines

Nzola de Magalhães, Takashi Murakami, Roger Heim, Lew Makings, Miguel Garcia-Guzman, Hisataka Kobayashi, Robert M. Hoffman, Michael Bouvet

Cancer Res (2015) 75 (15_Supplement): 2019.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2019

Published: 01 August 2015

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Journal Articles

Abstract 5117: Fluorescence-guided surgery of liver metastasis in orthotopic nude-mouse models

Takashi Murakami, Yukihiko Hiroshima, Shinji Miwa, Yano Shuya, Makoto Toneri, Mako Yamamoto, Masashi Momiyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Satoshi Hasegawa, Itaru Endo, Robert M. Hoffman

Cancer Res (2015) 75 (15_Supplement): 5117.

DOI: https://doi.org/10.1158/1538-7445.AM2015-5117

Published: 01 August 2015

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Journal Articles

Abstract 5123: Curative fluorescence-guided surgery of pancreatic cancer in combination with UVC irradiation in orthotopic mouse models

Yukihiko Hiroshima, Ali Maawy, Yong Zhang, Sho Sato, Takashi Murakami, Mako Yamamoto, Fuminari Uehara, Shinji Miwa, Shuya Yano, Masashi Momiyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman

Cancer Res (2015) 75 (15_Supplement): 5123.

DOI: https://doi.org/10.1158/1538-7445.AM2015-5123

Published: 01 August 2015

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Journal Articles

Abstract 3241: Tumor-targeting Salmonella typhimurium A1-R inhibits peritoneal dissemination of ovarian cancer and prolongs survival of the tumor-bearing nude mice

Yasunori Matsumoto, Shinji Miwa, Ming Zhao, Yong Zhang, Shuya Yano, Fuminari Uehara, Mako Yamamoto, Yukihiko Hiroshima, Makoto Toneri, Michael Bouvet, Hisahiro Matsubara, Robert Hoffmann

Cancer Res (2015) 75 (15_Supplement): 3241.

DOI: https://doi.org/10.1158/1538-7445.AM2015-3241

Published: 01 August 2015

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Journal Articles

Abstract 219: Fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore in combination with neoadjuvant chemotherapy inhibits metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model

Yukihiko Hiroshima, Ali Maawy, Yong Zhang, Takashi Murakami, Masashi Momiyama, Ryutaro Mori, Ryusei Matsuyama, Matthew H. Katz, Jason B. Fleming, Takashi Chishima, Kuniya Tanaka, Yasushi ichikawa, Itaru Endo, Robert M. Hoffman, Michael Bouvet

Cancer Res (2015) 75 (15_Supplement): 219.

DOI: https://doi.org/10.1158/1538-7445.AM2015-219

Published: 01 August 2015

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Journal Articles

Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models

Cristina A. Metildi, Sharmeela Kaushal, George A. Luiken, Robert M. Hoffman, Michael Bouvet

Cancer Res (2015) 75 (15_Supplement): 216.

DOI: https://doi.org/10.1158/1538-7445.AM2015-216

Published: 01 August 2015

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2 3 4 5

NARROW

Abstract 2786: Color-coded fluorescence-guided surgery in a patient-derived orthotopic xenograft (PDOX) nude mouse model of colon-cancer liver metastasis with ICG and a fluorescent antibody

Abstract 1658: Anti-CEACAM binding protein for fluorescence visualization of primary colon cancer in patient-derived orthotopic xenograph mouse models

Abstract 3733: Development of photoimmunotherapy for colon cancer in nude mice models

Abstract 3110: Heterokaryon formation and nuclear fusion of hybridizing cancer cells visualized in real time by color-coded imaging

Abstract 5900: Transforming growth factor-beta (TGF-β) inhibitor modulates cancer stroma in a pancreatic cancer orthotopic mouse model

Abstract 3729: Tumor-specific antibody labeling of pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model using a fluorescent humanized anti-CEA antibody

Abstract 1872: Fluorescence-guided surgery in the tumor microenvironment in a syngeneic mouse model of EL-4 lymphoma

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection

eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth

Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model

Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery

Abstract 4221: Imaging formation of the tumor microenvironment in orthotopic liver tumors in red fluorescent protein (RFP) transgenic nude mice

Abstract LB-263: Analysis of microenvironment effects on pancreatic cancer biomarker expression using a novel method for FFPE RNA extraction

Abstract 1456: Efficacy of photo-immunotherapy in combination with surgical resection on a pancreatic cancer patient derived orthotopic xenograft (PDOX)

Abstract 2019: Photoimmunotherapy with an anti-EGFR antibody conjugated to an IRDye700 results in extensive and rapid cell death in vitro and in vivo in human pancreatic cancer cell lines

Abstract 5117: Fluorescence-guided surgery of liver metastasis in orthotopic nude-mouse models

Abstract 5123: Curative fluorescence-guided surgery of pancreatic cancer in combination with UVC irradiation in orthotopic mouse models

Abstract 3241: Tumor-targeting Salmonella typhimurium A1-R inhibits peritoneal dissemination of ovarian cancer and prolongs survival of the tumor-bearing nude mice

Abstract 219: Fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore in combination with neoadjuvant chemotherapy inhibits metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model

Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models

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