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Michael Berger
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Journal Articles

Abstract 5440: Deep-learning model for tumor type classification enables enhanced clinical decision support in cancer diagnosis

Madison Darmofal, Shalabh Suman, Gurnit Atwal, Jie-Fu Chen, Anna Varghese, Jason C. Chang, Anoop Balakrishnan Rema, Aijazuddin Syed, Quaid Morris, Michael Berger
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5440.
https://doi.org/10.1158/1538-7445.AM2023-5440
Published: 04 April 2023
View article titled, Abstract 5440: Deep-learning model for tumor type classification enables enhanced clinical decision support in cancer diagnosis
Journal Articles

Abstract OT2-01-11: ctDNA-guided Adaptive Therapy Escalation in ER+ MBC: A Phase 1b Study with Letrozole, Palbociclib and Onapristone ER

Joshua Drago, Elaine Walsh, Mithat Gonen, Michael Berger, Mark E. Robson, Sarat Chandarlapaty, Pedram Razavi, Komal Jhaveri
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT2-01-11.
https://doi.org/10.1158/1538-7445.SABCS22-OT2-01-11
Published: 01 March 2023
View article titled, Abstract OT2-01-11: ctDNA-guided Adaptive Therapy Escalation in ER+ MBC: A Phase 1b Study with Letrozole, Palbociclib and Onapristone ER
Journal Articles

Abstract P4-02-18: Impact of clonal hematopoiesis on disease progression following CDK4/6 inhibitor therapy

Jacqueline Tao, Pablo Sanchez Vela, Anton Safonov, Emanuela Ferraro, Sebastia Franch Exposito, Kamal Menghrajani, Ryan Ptashkin, Elizabeth Comen, Lior Z. Braunstein, Mark E. Robson, Sarat Chandarlapaty, Jorge Reis-Filho, Michael Berger, Ahmet Zehir, Larry Norton, Ross Levine, Pedram Razavi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-18.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-18
Published: 01 March 2023
View article titled, Abstract P4-02-18: Impact of clonal hematopoiesis on disease progression following CDK4/6 inhibitor therapy
Journal Articles

Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy Lee, Sandra Cohen, Jane Park, Corinne Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa De Stanchina, Michael Berger, Anuradha Gopalan, Lukas Dow, Juan Miguel Mosquera, Himisha Beltran, Cora Sternberg, Ping Chi, Howard Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): B026.
https://doi.org/10.1158/1538-7445.CancEpi22-B026
Published: 01 December 2022
View article titled, Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Journal Articles

Abstract 56: MSK-ACCESS Heme: A cell-free DNA next-generation sequencing assay to identify somatic alterations in patients with lymphoma

Sara E. DiNapoli, Coleman Spence, Erika Gedvilaite, Anita Bowman, Monica Diosdado, Anna Razumova, Dana Tsui, Gilles A. Salles, Connie Batlevi, Gottfried von Keudell, Ryan Ptashkin, Ahmet Zehir, Michael Berger, A Rose Brannon, Ryma Benayed, Maria Arcila
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 56.
https://doi.org/10.1158/1538-7445.AM2022-56
Published: 15 June 2022
View article titled, Abstract 56: MSK-ACCESS Heme: A cell-free DNA next-generation sequencing assay to identify somatic alterations in patients with lymphoma
Journal Articles

Abstract PS13-46: Immunomodulation with dexamethasone in neoadjuvant chemotherapy for triple negative breast cancer

Daniel Goldstein, Mahmoud Kassem, Dionisia Quiroga, Abdul Miah, Craig Vargo, Namrata Vilas Shinde, Michael Berger, Nicole Williams, Daniel Stover, Sagar Sardesai, Maryam Lustberg, Bhuvaneswari Ramaswamy, Gary Tozbikian, Patrick Schnell, Mathew Cherian
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-46.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-46
Published: 15 February 2021
View article titled, Abstract PS13-46: Immunomodulation with dexamethasone in neoadjuvant chemotherapy for triple negative breast cancer
Journal Articles

Abstract 1109: Integrative analysis of clinical and genomic information identifies predictive markers of metastatic risk

Christopher J. Fong, Francisco Sanchez-Vega, Bastien Ngyuen, Anisha Luthra, Subhiksha Nandakumar, Henry Walch, Walid Chatila, Arjun Rajanna, Ahmet Zehir, Michael Berger, Jianjiong Gao, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1109.
https://doi.org/10.1158/1538-7445.AM2020-1109
Published: 15 August 2020
View article titled, Abstract 1109: Integrative analysis of clinical and genomic information identifies predictive markers of metastatic risk
Journal Articles

Abstract 3208: OncoKB, a precision oncology knowledgebase

Sarah Suehnholz, Hongxin Zhang, Moriah Nissan, Ritika Kundra, Jing Su, Lindsay LaFave, Kinisha Gala, Chad Vanderbilt, Maria Arcila, Marc Ladanyi, Michael Berger, Ahmet Zehir, Julia E. Rudolph, Paul Sabbatini, Ross Levine, Ahmet Dogan, Jianjiong Gao, David B. Solit, Nikolaus Schultz, Debyani Chakravarty
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3208.
https://doi.org/10.1158/1538-7445.AM2020-3208
Published: 15 August 2020
View article titled, Abstract 3208: OncoKB, a precision oncology knowledgebase
Journal Articles

Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis

Kelly L. Bolton, Ryan N. Ptashkin, Teng Gao, Lior Braunstein, Sean M. Devlin, Minal Patel, Antonin Berthon, Aijazuddin Syed, Mariko Yabe, Catherine Coombs, Nicole M. Caltabellotta, Mike Walsh, Ken Offit, Zsofia Stadler, Choonsik Lee, Paul Pharoah, Konrad H. Stopsack, Barbara Spitzer, Simon Mantha, James Fagin, Laura Boucai, Christopher J. Gibson, Benjamin Ebert, Andrew L. Young, Todd Druley, Koichi Takahashi, Nancy Gillis, Markus Ball, Eric Padron, David Hyman, Jose Baselga, Larry Norton, Stuart Gardos, Virginia Klimek, Howard Scher, Dean Bajorin, Eder Paraiso, Ryma Benayed, Maria Arcilla, Marc Ladanyi, David Solit, Michael Berger, Martin Tallman, Montserrat Garcia-Closas, Nilanjan Chatterjee, Luis Diaz, Ross Levine, Lindsay Morton, Ahmet Zehir, Elli Papaemmanuil
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5703.
https://doi.org/10.1158/1538-7445.AM2020-5703
Published: 15 August 2020
View article titled, Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
Journal Articles

Abstract 1387: Tracking minimal residual disease in post-operative cell-free DNA using MSK-ACCESS

Maysun M. Hasan, Juber Patel, Ian Johnson, Fanli Meng, Grittney K. Tam, Xiaohong Jing, Julie L. Yang, A. Rose Brannon, Jayakumaran Gowtham, Dennis P. Stephens, Monica Diosdado, Ryma Benayed, Ahmet Zehir, Chin-Tung Chen, Martin R. Weiser, Dana Tsui, Brian Houck-Loomis, Michael Berger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1387.
https://doi.org/10.1158/1538-7445.AM2019-1387
Published: 01 July 2019
View article titled, Abstract 1387: Tracking minimal residual disease in post-operative cell-free DNA using MSK-ACCESS
Journal Articles

Abstract 4158: Dissecting the role of zygosity and lineage in Lynch Syndrome-associated microsatellite Instability

Preethi Srinivasan, Chaitanya Bandlamudi, Jinru Shia, Alicia S. Latham, Philip Jonsson, Alexander Penson, Sumit Middha, Jackie Hechtman, Ahmet Zehir, Allison Richards, Shweta Chawan, Yelena Kemel, Diana Mandelker, Liying Zhang, David Hyman, Marc Ladanyi, Mark Robson, Kenneth Offit, David Solit, Barry Taylor, Michael Berger, Zsofia Stadler
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4158.
https://doi.org/10.1158/1538-7445.AM2019-4158
Published: 01 July 2019
View article titled, Abstract 4158: Dissecting the role of zygosity and lineage in Lynch Syndrome-associated microsatellite Instability
Journal Articles

Abstract 2516: A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA

Juber Patel, Maysun Hasan, Fanli Meng, Xiaohong Jing, Grittney Tam, Ian Johnson, Youyun Zheng, Chaitanya Bandlamudi, Caitlin Stewart, Helen Won, Oliver Hampton, Alison Schram, Ezra Rosen, Alexander Drilon, Anna Varghese, David Hyman, Dana Tsui, Brian Houck-Loomis, Michael Berger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2516.
https://doi.org/10.1158/1538-7445.AM2019-2516
Published: 01 July 2019
View article titled, Abstract 2516: A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA
Journal Articles

Abstract 1572: Inherited truncating RAD52 variant discovered using integrated germline- somatic analysis predicts clinical outcome in patients with lung cancers

Semanti Mukherjee, Preethi Srinivasan, Chaitanya Bandlamudi, Matthew D. Hellmann, Vignesh Ravichandran, Myvizhi Esai Selvan, Yelena Kemel, Diana Mandelker, Marjorie Zauderer, Michael Walsh, Ahmet Zehir, Maria I Carlo, Karen Cadoo, Steven M Lipkin, Marc Ladanyi, David Solit, Mark Robson, Liying Zhang, David Jones, Charles Rudin, Robert Klein, Zsofia Stadler, Joseph Vijai, Zeynep Gumus, Barry Taylor, Michael Berger, Kenneth Kenneth
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1572.
https://doi.org/10.1158/1538-7445.AM2019-1572
Published: 01 July 2019
View article titled, Abstract 1572: Inherited truncating <em>RAD52</em> variant discovered using integrated germline- somatic analysis predicts clinical outcome in patients with lung cancers
Journal Articles

Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2

Pushkar Malakar, Ilan Stein, Amijai Saragovi, Roni Winkler, Noam Stern-Ginossar, Michael Berger, Eli Pikarsky, Rotem Karni
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2480–2493.
https://doi.org/10.1158/0008-5472.CAN-18-1432
Published: 15 May 2019
View article titled, Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2
Open the PDF for Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2 in another window
Includes: Supplementary data
Journal Articles

Abstract 5598: Development and optimization of a comprehensive high-sensitivity NGS cancer assay and bioinformatics pipeline for plasma cfDNA profiling

Juber Patel, Maysun Hasan, Fanli Meng, Xiaohong Jing, Dilmi Perera, Jonathan Reichel, Erika Gedvilaite, Julie Yang, Maha Shady, Sandeep Raj, Preethi Srinivasan, Ian Johnson, Jiashi Wang, Mirna Jarosz, Aliaksandra Samoila, Agnes Viale, Bob Li, Pedram Razavi, Dana Tsui, Michael Berger
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5598.
https://doi.org/10.1158/1538-7445.AM2018-5598
Published: 01 July 2018
View article titled, Abstract 5598: Development and optimization of a comprehensive high-sensitivity NGS cancer assay and bioinformatics pipeline for plasma cfDNA profiling
Journal Articles

Abstract 5500: KMT2C directs estrogen receptor activity in normal and transformed mammary cells

Kinisha Gala, Amit Sinha, Francisco Sanchez-Vega, Young Rock Chung, James Hseih, Michael Berger, Nikolaus Schultz, Alessandro Pastore, Omar Abdel-Wahab, Sarat Chandarlapaty
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5500.
https://doi.org/10.1158/1538-7445.AM2017-5500
Published: 01 July 2017
View article titled, Abstract 5500: KMT2C directs estrogen receptor activity in normal and transformed mammary cells
Journal Articles

Abstract 298: Amplification of mutant ERBB2 drives resistance to the irreversible kinase inhibitor neratinib in ERBB2-mutated breast cancer patients

F Javier Carmona, David Hyman, Gary Ulaner, Joe Erinjeri, Nancy Bouvier, Helen Won, Richard Cutler, Al Alani, Michael Berger, José Baselga, Maurizio Scaltriti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 298.
https://doi.org/10.1158/1538-7445.AM2016-298
Published: 15 July 2016
View article titled, Abstract 298: Amplification of mutant ERBB2 drives resistance to the irreversible kinase inhibitor neratinib in ERBB2-mutated breast cancer patients
Journal Articles

Abstract 2640: Clonal hematopoiesis identified by matched-normal blood sequencing of solid tumor patients without hematologic malignancy is common and is associated with decreased overall survival

Catherine Coombs, Ahmet Zehir, Sean Devlin, Sumit Middha, Donavan Cheng, Ashwin Kishtagari, David Hyman, David Solit, Mark Robson, Jose Baselga, Maria Arcila, Martin Tallman, Ross Levine, Michael Berger
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2640.
https://doi.org/10.1158/1538-7445.AM2016-2640
Published: 15 July 2016
View article titled, Abstract 2640: Clonal hematopoiesis identified by matched-normal blood sequencing of solid tumor patients without hematologic malignancy is common and is associated with decreased overall survival
Journal Articles

Abstract 863: Differential activity and SERD sensitivity of clinical ESR1 mutations

Weiyi Toy, Hazel Weir, Pedram Razavi, Michael Berger, Wai Lin Wong, Elisa De Stanchina, Joœe Baselga, Sarat Chandarlapaty
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 863.
https://doi.org/10.1158/1538-7445.AM2016-863
Published: 15 July 2016
View article titled, Abstract 863: Differential activity and SERD sensitivity of clinical ESR1 mutations
Journal Articles

Abstract CT330: Phase I study of PI3Kα inhibitor BYL719 + aromatase inhibitor (AI) in patients (pts) with hormone receptor-positive (HR+) metastatic breast cancer (MBC)

Payal D. Shah, Mary E. Moynahan, Shanu Modi, Nicola Hamilton, Betty Ann Caravella, Stephen Zamora, Chau Dang, Theresa Gilewski, Tiffany Traina, Elizabeth Comen, Steven M. Sugarman, Gabriella D'Andrea, Diana Lake, Shari Goldfarb, Sujata Patil, Anne Covey, Michael Berger, Mario Lacouture, Larry Norton, Clifford A. Hudis, Jose Baselga, Sarat Chandarlapaty, Maura Dickler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT330.
https://doi.org/10.1158/1538-7445.AM2015-CT330
Published: 01 August 2015
View article titled, Abstract CT330: Phase I study of PI3Kα inhibitor BYL719 + aromatase inhibitor (AI) in patients (pts) with hormone receptor-positive (HR+) metastatic breast cancer (MBC)