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Abstract CT093: Cancer Core Europe - Basket of Baskets - first results from module 1: Atezolizumab in genomically selected populations

Irene Brana, Christophe Massard, Frans Opdam, Richard D. Baird, Luigi De Petris, Richard Schlenk, Claudio Vernieri, David Tamborero, Shubha Anand, Etienne Rouleau, Adria Lopez, Nikos Demiris, Paolo Nuciforo, Elena Provenzano, Daniel Huebschmann, Katrin Pfütze, Maria Pernemalm, Daniel Vis, Ana Vivancos, Valtteri Wirta, Peter Horak, Omar Saavedra, Marloes van Dongen, Emily Barker, Susana Aguilar, Elena Chavarria, Xenia Villalobos, Marta Rotxes, Arantxa Romero, Francisco Martínez-Jiménez, Alena Gros, Anna Pedrola, Cristina Viaplana, Neeltje Steeghs, Elena Garralda, Cancer Core Europe - Basket of Baskets study team, Alejandro Piris, Karim Fizazi, Fabrice Barlesi, Karen Barker, Michiel Heijden, Wilbert Zwart, Filippo de Braud, Elias Arner, Janne Lehtiö, Michael Baumann, Stefan Fröhling, Josep Tabernero, Javier Carmona, Jordi Rodon

Cancer Res (2025) 85 (8_Supplement_2): CT093.

https://doi.org/10.1158/1538-7445.AM2025-CT093

Published: 25 April 2025

View articletitled, Abstract CT093: Cancer Core Europe - Basket of Baskets - first results from module 1: Atezolizumab in genomically selected populations

Journal Articles

Abstract 4756: A SPP1-EGFR pathway links stem-like properties of KRAS-mutated lung cancer to radiation resistance

Meng Wang, Jing Han, Lynnette Marcar, Josh Black, Qi Liu, Xiangyong Li, Kshithija Nagulapalli, Lecia V. Sequist, Raymond H. Mak, Cyril H. Benes, Theodore S. Hong, Kristin Gurtner, Mechthild Krause, Michael Baumann, Jing X. Kang, Johnathan R. Whetstine, Henning Willers

Cancer Res (2017) 77 (13_Supplement): 4756.

https://doi.org/10.1158/1538-7445.AM2017-4756

Published: 01 July 2017

View articletitled, Abstract 4756: A SPP1-EGFR pathway links stem-like properties of KRAS-mutated lung cancer to radiation resistance

Journal Articles

Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin–EGFR Pathway

Cancer Res (2017) 77 (8): 2018–2028.

https://doi.org/10.1158/0008-5472.CAN-16-0808

Published: 13 April 2017

View articletitled, Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin–EGFR Pathway

Includes: Supplementary data

Journal Articles

An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

Cancer Res (2016) 76 (9): 2637–2651.

https://doi.org/10.1158/0008-5472.CAN-15-2116

Published: 01 May 2016

View articletitled, An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

Includes: Supplementary data

Journal Articles

Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells

Monica Cojoc, Claudia Peitzsch, Ina Kurth, Franziska Trautmann, Leoni A. Kunz-Schughart, Gennady D. Telegeev, Eduard A. Stakhovsky, John R. Walker, Karl Simin, Stephen Lyle, Susanne Fuessel, Kati Erdmann, Manfred P. Wirth, Mechthild Krause, Michael Baumann, Anna Dubrovska

Cancer Res (2015) 75 (7): 1482–1494.

https://doi.org/10.1158/0008-5472.CAN-14-1924

Published: 31 March 2015

View articletitled, Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells

Includes: Supplementary data

Journal Articles

Abstract LB-209: Chromatin condensation in KRAS-mutant lung cancer as a therapeutic target: challenging the paradigm of associating KRAS mutation with EGFR inhibitor resistance

Meng Wang, Ashley M. Kern, Marieke Hülskötter, Patricia Greninger, Anurag Singh, Yunfeng Pan, Dipanjan Chowdhury, Mechthild Krause, Michael Baumann, Cyril H. Benes, Jason A. Efstathiou, Jeff Settleman, Henning Willers

Cancer Res (2014) 74 (19_Supplement): LB-209.

https://doi.org/10.1158/1538-7445.AM2014-LB-209

Published: 01 October 2014

View articletitled, Abstract LB-209: Chromatin condensation in KRAS-mutant lung cancer as a therapeutic target: challenging the paradigm of associating KRAS mutation with EGFR inhibitor resistance

Journal Articles

EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation

Cancer Res (2014) 74 (10): 2825–2834.

https://doi.org/10.1158/0008-5472.CAN-13-3157

Published: 14 May 2014

View articletitled, EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation

Includes: Supplementary data

Journal Articles

Abstract LB-211: beta1 integrin targeting results in radiosensitization by controlling DNA repair mechanisms and chromatin organization

Ellen Dickreuter, Katja Storch, Iris Eke, Mechthild Krause, Michael Baumann, Nils Cordes

Cancer Res (2012) 72 (8_Supplement): LB-211.

https://doi.org/10.1158/1538-7445.AM2012-LB-211

Published: 15 April 2012

View articletitled, Abstract LB-211: beta1 integrin targeting results in radiosensitization by controlling DNA repair mechanisms and chromatin organization

Journal Articles

EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks

Meng Wang, Fabian Morsbach, David Sander, Liliana Gheorghiu, Akash Nanda, Cyril Benes, Malte Kriegs, Mechthild Krause, Ekkehard Dikomey, Michael Baumann, Jochen Dahm-Daphi, Jeffrey Settleman, Henning Willers

Cancer Res (2011) 71 (19): 6261–6269.

https://doi.org/10.1158/0008-5472.CAN-11-0213

Published: 29 September 2011

View articletitled, EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks

Includes: Supplementary data

Journal Articles

Enhanced Susceptibility of Irradiated Tumor Vessels to Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibition

Daniel Zips, Wolfgang Eicheler, Peter Geyer, Franziska Hessel, Annegret Dörfler, Howard D. Thames, Martin Haberey, Michael Baumann

Cancer Res (2005) 65 (12): 5374–5379.

https://doi.org/10.1158/0008-5472.CAN-04-3379

Published: 15 June 2005

View articletitled, Enhanced Susceptibility of Irradiated Tumor Vessels to Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibition

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Abstract CT093: Cancer Core Europe - Basket of Baskets - first results from module 1: Atezolizumab in genomically selected populations

Abstract 4756: A SPP1-EGFR pathway links stem-like properties of KRAS-mutated lung cancer to radiation resistance

Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin–EGFR Pathway

An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells

Abstract LB-209: Chromatin condensation in KRAS-mutant lung cancer as a therapeutic target: challenging the paradigm of associating KRAS mutation with EGFR inhibitor resistance

EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation

Abstract LB-211: beta1 integrin targeting results in radiosensitization by controlling DNA repair mechanisms and chromatin organization

EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks

Enhanced Susceptibility of Irradiated Tumor Vessels to Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibition

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