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Journal Articles

Abstract 1628: A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects

Cancer Res (2023) 83 (7_Supplement): 1628.

https://doi.org/10.1158/1538-7445.AM2023-1628

Published: 04 April 2023

View article titled, Abstract 1628: A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects

Journal Articles

Abstract 3928: The pan-CLK/DYRK inhibitor cirtuvivint selectively disrupts alternative splicing and has broad anti-tumor activity in preclinical models

Elizabeth A. McMillan, Carine Bossard, Emily Creger, Carsten Merkwirth, Raffaella Pippa, Matthew Jarvis, Krishna Sriram, Melinda Pedraza, Maureen Ibanez, Deepti Bhat, Carolyn Lai, Josh Stewart, Brian Eastman, Chi-Ching Mak, Michael A. White, Darrin Beaupre

Cancer Res (2022) 82 (12_Supplement): 3928.

https://doi.org/10.1158/1538-7445.AM2022-3928

Published: 15 June 2022

View article titled, Abstract 3928: The pan-CLK/DYRK inhibitor cirtuvivint selectively disrupts alternative splicing and has broad anti-tumor activity in preclinical models

Journal Articles

TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer

Jonathan M. Cooper, Yi-Hung Ou, Elizabeth A. McMillan, Rachel M. Vaden, Aubhishek Zaman, Brian O. Bodemann, Gurbani Makkar, Bruce A. Posner, Michael A. White

Cancer Res (2017) 77 (18): 5077–5094.

https://doi.org/10.1158/0008-5472.CAN-17-0829

Published: 14 September 2017

View article titled, TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract PR04: Translational control of human colon tumor cell survival

Eyerusalem M. Lemma, Jamie L. McCall, Beth K. Clymer, David L. Kelly, Michael A. White, Robert E. Lewis

Cancer Res (2017) 77 (6_Supplement): PR04.

https://doi.org/10.1158/1538-7445.Transcontrol16-PR04

Published: 14 March 2017

View article titled, Abstract PR04: Translational control of human colon tumor cell survival

Journal Articles

Abstract 1252: TIMELESS is a KSR1-like effector of Ras-driven colon tumorigenesis

Beth K. Clymer, Kurt W. Fisher, David L. Kelly, Michael A. White, Robert E. Lewis

Cancer Res (2016) 76 (14_Supplement): 1252.

https://doi.org/10.1158/1538-7445.AM2016-1252

Published: 15 July 2016

View article titled, Abstract 1252: TIMELESS is a KSR1-like effector of Ras-driven colon tumorigenesis

Journal Articles

Abstract A2-06: An in vivo shRNA functional genomics screen identifies transcriptional and epigenetic regulators that are essential in lung tumorigenesis

Suzie K. Hight, Elizabeth McMillan, Chunli Shao, Luc Girard, Jaime Rodriguez Canales, Michael A. White, Ignacio I. Wistuba, David Mangelsdorf, John D. Minna

Cancer Res (2015) 75 (22_Supplement_1): A2-06.

https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-06

Published: 15 November 2015

View article titled, Abstract A2-06: An in vivo shRNA functional genomics screen identifies transcriptional and epigenetic regulators that are essential in lung tumorigenesis

Journal Articles

Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer

Lindsey K. Boroughs, Pei-Hsuan Chen, Ling Cai, Mirna Rodriguez, Winter Zhang, Kenneth E. Huffman, Lauren A. Byers, Luc Girard, Adi F. Gazdar, John V. Heymach, Michael A. White, John D. Minna, Ethan Emberley, Alison Pan, Frank Parlati, Ralph J. DeBerardinis

Cancer Res (2015) 75 (15_Supplement): 4710.

https://doi.org/10.1158/1538-7445.AM2015-4710

Published: 01 August 2015

View article titled, Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer

Journal Articles

Genetic Mutation of p53 and Suppression of the miR-17∼92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling

Robert Borkowski, Liqin Du, Zhenze Zhao, Elizabeth McMillan, Adam Kosti, Chin-Rang Yang, Milind Suraokar, Ignacio I. Wistuba, Adi F. Gazdar, John D. Minna, Michael A. White, Alexander Pertsemlidis

Cancer Res (2015) 75 (4): 666–675.

https://doi.org/10.1158/0008-5472.CAN-14-1329

Published: 15 February 2015

View article titled, Genetic Mutation of p53 and Suppression of the miR-17∼92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling

Includes: Supplementary data

Journal Articles

Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer

Cancer Res (2013) 73 (19_Supplement): C16.

https://doi.org/10.1158/1538-7445.FBCR13-C16

Published: 15 May 2014

View article titled, Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer

Journal Articles

RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage

Hsiang Ho, Jayavani Aruri, Rubina Kapadia, Hootan Mehr, Michael A. White, Anand K. Ganesan

Cancer Res (2012) 72 (21): 5516–5528.

https://doi.org/10.1158/0008-5472.CAN-12-0775

Published: 31 October 2012

View article titled, RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage

Includes: Supplementary data

Journal Articles

Abstract SY39-01: Harnessing cancer genome diversity for intervention target discovery and development

Michael A. White

Cancer Res (2012) 72 (8_Supplement): SY39-01.

https://doi.org/10.1158/1538-7445.AM2012-SY39-01

Published: 15 April 2012

View article titled, Abstract SY39-01: Harnessing cancer genome diversity for intervention target discovery and development

Journal Articles

Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth

Ugur Eskiocak, Sang Bum Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring E. Wright, Michael A. White, Jerry W. Shay

Cancer Res (2011) 71 (13): 4359–4365.

https://doi.org/10.1158/0008-5472.CAN-11-0794

Published: 30 June 2011

View article titled, Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth

Includes: Supplementary data

Journal Articles

Abstract SY01-02: Mapping the landscape of conditional vulnerabilities in non-small cell lung cancer

Hyunseok Kim, Hua Gao, John Minna, Bruce Posner, Michael A. White

Cancer Res (2011) 71 (8_Supplement): SY01-02.

https://doi.org/10.1158/1538-7445.AM2011-SY01-02

Published: 15 April 2011

View article titled, Abstract SY01-02: Mapping the landscape of conditional vulnerabilities in non-small cell lung cancer

Journal Articles

Abstract 2207: Functional interrogation of the colorectal cancer genome identifies numerous suppressors of anchorage-independent growth

Ugur Eskiocak, Sang B. Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring E. Wright, Michael A. White, Jerry W. Shay

Cancer Res (2011) 71 (8_Supplement): 2207.

https://doi.org/10.1158/1538-7445.AM2011-2207

Published: 15 April 2011

View article titled, Abstract 2207: Functional interrogation of the colorectal cancer genome identifies numerous suppressors of anchorage-independent growth

Journal Articles

Tumor Antigen Acrosin Binding Protein Normalizes Mitotic Spindle Function to Promote Cancer Cell Proliferation

Angelique W. Whitehurst, Yang Xie, Scott C. Purinton, Kathryn M. Cappell, Jackie T. Swanik, Brittany Larson, Luc Girard, John O. Schorge, Michael A. White

Cancer Res (2010) 70 (19): 7652–7661.

https://doi.org/10.1158/0008-5472.CAN-10-0840

Published: 29 September 2010

View article titled, Tumor Antigen Acrosin Binding Protein Normalizes Mitotic Spindle Function to Promote Cancer Cell Proliferation

Journal Articles

The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame ( INK4a/ARF ) Locus Encoded Proteins p16^INK4a and p19^ARF Repress Cyclin D1 Transcription through Distinct cis Elements

Mark D’Amico, Kongming Wu, Maofu Fu, Mahadev Rao, Chris Albanese, Robert G. Russell, Hanzhou Lian, David Bregman, Michael A. White, Richard G. Pestell

Cancer Res (2004) 64 (12): 4122–4130.

https://doi.org/10.1158/0008-5472.CAN-03-2519

Published: 17 June 2004

View article titled, The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame ( INK4a/ARF ) Locus Encoded Proteins p16INK4a and p19ARF Repress Cyclin D1 Transcription through Distinct cis Elements

Includes: Supplementary data

Journal Articles

Different Roles for Caveolin-1 in the Development of Non-Small Cell Lung Cancer versus Small Cell Lung Cancer

Noriaki Sunaga, Kuniharu Miyajima, Makoto Suzuki, Mitsuo Sato, Michael A. White, Ruben D. Ramirez, Jerry W. Shay, Adi F. Gazdar, John D. Minna

Cancer Res (2004) 64 (12): 4277–4285.

https://doi.org/10.1158/0008-5472.CAN-03-3941

Published: 17 June 2004

View article titled, Different Roles for Caveolin-1 in the Development of Non-Small Cell Lung Cancer versus Small Cell Lung Cancer

Journal Articles

Raf-induced Transformation Requires an Interleukin 1 Autocrine Loop

Terry Vale, Teri T. Ngo, Michael A. White, Peter E. Lipsky

Cancer Res (2001) 61 (2): 602–607.

Published: 01 January 2001

View article titled, Raf-induced Transformation Requires an Interleukin 1 Autocrine Loop

NARROW

Abstract 1628: A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects

Abstract 3928: The pan-CLK/DYRK inhibitor cirtuvivint selectively disrupts alternative splicing and has broad anti-tumor activity in preclinical models

TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer

Abstract PR04: Translational control of human colon tumor cell survival

Abstract 1252: TIMELESS is a KSR1-like effector of Ras-driven colon tumorigenesis

Abstract A2-06: An in vivo shRNA functional genomics screen identifies transcriptional and epigenetic regulators that are essential in lung tumorigenesis

Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer

Genetic Mutation of p53 and Suppression of the miR-17∼92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling

Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer

RhoJ Regulates Melanoma Chemoresistance by Suppressing Pathways That Sense DNA Damage

Abstract SY39-01: Harnessing cancer genome diversity for intervention target discovery and development

Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth

Abstract SY01-02: Mapping the landscape of conditional vulnerabilities in non-small cell lung cancer

Abstract 2207: Functional interrogation of the colorectal cancer genome identifies numerous suppressors of anchorage-independent growth

Tumor Antigen Acrosin Binding Protein Normalizes Mitotic Spindle Function to Promote Cancer Cell Proliferation

The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame ( INK4a/ARF ) Locus Encoded Proteins p16^INK4a and p19^ARF Repress Cyclin D1 Transcription through Distinct cis Elements

Different Roles for Caveolin-1 in the Development of Non-Small Cell Lung Cancer versus Small Cell Lung Cancer

Raf-induced Transformation Requires an Interleukin 1 Autocrine Loop

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