1-20 of 62
Michael A. Davies
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

Brian S. White, Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang, Yvonne A. Evrard, Li Chen, Ali Foroughi pour, John D. Landua, R. Jay Mashl, Sherri R. Davies, Bingliang Fang, Maria Gabriela Raso, Kurt W. Evans, Matthew H. Bailey, Yeqing Chen, Min Xiao, Jill C. Rubinstein, Brian J. Sanderson, Michael W. Lloyd, Sergii Domanskyi, Lacey E. Dobrolecki, Maihi Fujita, Junya Fujimoto, Guanghua Xiao, Ryan C. Fields, Jacqueline L. Mudd, Xiaowei Xu, Melinda G. Hollingshead, Shahanawaz Jiwani, Saul Acevedo, PDXNet Consortium, Brandi N. Davis-Dusenbery, Peter N. Robinson, Jeffrey A. Moscow, James H. Doroshow, Nicholas Mitsiades, Salma Kaochar, Chong-xian Pan, Luis G. Carvajal-Carmona, Alana L. Welm, Bryan E. Welm, Ramaswamy Govindan, Shunqiang Li, Michael A. Davies, Jack A. Roth, Funda Meric-Bernstam, Yang Xie, Meenhard Herlyn, Li Ding, Michael T. Lewis, Carol J. Bult, Dennis A. Dean, II, Jeffrey H. Chuang
Journal: Cancer Research
Cancer Res (2024) 84 (13): 2060–2072.
https://doi.org/10.1158/0008-5472.CAN-23-1349
Published: 02 July 2024
View articletitled, A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis
Open the PDF for A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis in another window
Includes: Supplementary data
Journal Articles

Abstract CT176: OBX-115 engineered tumor-infiltrating lymphocyte (TIL) cell therapy induced deepening and durable responses without interleukin 2 (IL2) in patients (pts) with immune checkpoint inhibitor (ICI)-resistant unresectable or metastatic melanoma

Rodabe N. Amaria, Jennifer L. McQuade, Michael A. Davies, Isabella C. Glitza Oliva, Steffy Jose, Erik N. Cressman, Ashlynd L. Clausell, Roland Bassett, Sapna Patel, Adi Diab, Hussein A. Tawbi, Michael K. Wong, Alexandra P. Ikeguchi, Madan Jagasia, Giridharan Ramsingh, Prakash Prabhakar, Raina Duan, Parameswaran Hari
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT176.
https://doi.org/10.1158/1538-7445.AM2024-CT176
Published: 05 April 2024
View articletitled, Abstract CT176: OBX-115 engineered tumor-infiltrating lymphocyte (TIL) cell therapy induced deepening and durable responses without interleukin 2 (IL2) in patients (pts) with immune checkpoint inhibitor (ICI)-resistant unresectable or metastatic melanoma
Journal Articles

Abstract 3605: Phase II study of pembrolizumab in conjunction with lymphodepletion, TIL ACT, and high- or low-dose IL-2 in patients with metastatic melanoma

Merve Hasanov, Simin Kiany, Marie-Andrée Forget, Roland L. Bassett, Michael A. Davies, Adi Diab, Jeffrey E. Gershenwald, Isabella C. Glitza, Jeffrey E. Lee, Anthony Lucci, Jennifer L. McQuade, Sapna P. Patel, Merrick I. Ross, Hussein A. Tawbi, Jennifer Wargo, Michael K. Wong, Chantale Bernatchez, Patrick Hwu, Cara Haymaker, Rodabe N. Amaria
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3605.
https://doi.org/10.1158/1538-7445.AM2024-3605
Published: 22 March 2024
View articletitled, Abstract 3605: Phase II study of pembrolizumab in conjunction with lymphodepletion, TIL ACT, and high- or low-dose IL-2 in patients with metastatic melanoma
Journal Articles

Abstract 4444: Targeting PI3K isoforms to improve the effectiveness of T cell mediated immunotherapy

Ritu Bohat, Xiaofang Liang, Chunyu Xu, Yitao Tang, Jiakai Hou, Nicholas A. Egan, Leilei Shi, Ashley Guerrero, Roshni Jaffery, Elizabeth M. Burton, Han Liang, Hussein Tawbi, Michael A. Davies, Weiyi Peng
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4444.
https://doi.org/10.1158/1538-7445.AM2023-4444
Published: 04 April 2023
View articletitled, Abstract 4444: Targeting PI3K isoforms to improve the effectiveness of T cell mediated immunotherapy
Journal Articles

Abstract 5788: Single-cell and spatial transcriptomic mapping of human renal cell carcinoma brain metastases uncovers actionable immune-resistance targets

Elshad Hasanov, Truong Nguyen Anh Lam, Jerome Lin, Patrick K. Reville, Merve Hasanov, Anna K. Casasent, David Shih, Sahin Hanalioglu, Mehmet Asim Bilen, Omar Alhalabi, Berrin Babaoglu, Baylar Baylarov, Adeboye O. Osunkoya, Lisa M. Norberg, Joy Gumin, Tuan M. Tran, Jianzhuo Li, Anh G. Hoang, Haidee D. Chancoco, Brittany C. Parker Kerrigan, Erika J. Thompson, Betty YS Kim, Dima Suki, Melike Mut, Figen Soylemezoglu, Giannicola Genovese, Kadir C. Akdemir, Hussain A. Tawbi, Nizar M. Tannir, Florencia McAllister, Michael A. Davies, Padmanee Sharma, Jason Huse, Frederick Lang, Nicholas Navin, Eric Jonasch
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5788.
https://doi.org/10.1158/1538-7445.AM2023-5788
Published: 04 April 2023
View articletitled, Abstract 5788: Single-cell and spatial transcriptomic mapping of human renal cell carcinoma brain metastases uncovers actionable immune-resistance targets
Journal Articles

Abstract 6425: Functional roles of enhancers in immune microenvironment & immunotherapy response

Kunal Rai, Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Firas Youssef Kreidieh, Christopher Terranova, Kyriakitsa Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarrantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Hussein Tawbi, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6425.
https://doi.org/10.1158/1538-7445.AM2023-6425
Published: 04 April 2023
View articletitled, Abstract 6425: Functional roles of enhancers in immune microenvironment & immunotherapy response
Journal Articles

Abstract 5407: A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis

Brian S. White, Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang, Yvonne A. Evrard, John David Landua, R Jay Mashl, Sherri R. Davies, Bingliang Fang, Maria Gabriela Raso, Kurt W. Evans, Matthew H. Bailey, Yeqing Chen, Min Xiao, Jill Rubinstein, Ali Foroughi pour, Lacey Elizabeth Dobrolecki, Maihi Fujita, Junya Fujimoto, Guanghua Xiao, Ryan C. Fields, Jacqueline L. Mudd, Xiaowei Xu, Melinda G. Hollingshead, Shahanawaz Jiwani, PDXNet consortium, Tiffany A. Wallace, Jeffrey A. Moscow, James H. Doroshow, Nicholas Mitsiades, Salma Kaochar, Chong-xian Pan, Moon S. Chen, Luis G. Carvajal-Carmona, Alana L. Welm, Bryan E. Welm, Ramaswamy Govindan, Shunqiang Li, Michael A. Davies, Jack A. Roth, Funda Meric-Bernstam, Yang Xie, Meenhard Herlyn, Li Ding, Michael T. Lewis, Carol J. Bolt, Dennis A. Dean, Jeffrey H. Chuang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5407.
https://doi.org/10.1158/1538-7445.AM2023-5407
Published: 04 April 2023
View articletitled, Abstract 5407: A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis
Journal Articles

Abstract A005: The aged tumor microenvironment influences tolerance to targeted therapy via NR2F1 overexpression in BRAF-mutant melanoma

Manoela Tiago, Timothy J. Purwin, Mitchell E. Fane, Yash Chhabra, Jessica L. F. Teh, Rama Kadamb, Weijia Cai, Inna Chervoneva, Sheera Rosenbaum, Vivian Chua, Nir Hacohen, Michael A. Davies, Jessie Villanieva, Ashani T. Weeraratna, Claudia Capparelli, Julio A. Aguirre-Ghiso, Andrew E. Aplin
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_1): A005.
https://doi.org/10.1158/1538-7445.AGCA22-A005
Published: 15 January 2023
View articletitled, Abstract A005: The aged tumor microenvironment influences tolerance to targeted therapy via NR2F1 overexpression in BRAF-mutant melanoma
Journal Articles

Abstract IA019: Unique features and dependencies of brain metastases

Michael A. Davies
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_2): IA019.
https://doi.org/10.1158/1538-7445.METASTASIS22-IA019
Published: 15 January 2023
View articletitled, Abstract IA019: Unique features and dependencies of brain metastases
Journal Articles

Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis

Johannes C. Melms, Jana Biermann, Amit Dipak Amin, Yiping Wang, Somnath Tagore, Massimo Andreatta, Ajay Nair, Meri Rogava, Patricia Ho, Lindsay A. Caprio, Zachary H. Walsh, Shivem Shah, Daniel H. Vacarro, Blake Caldwell, Adrienne M. Luoma, Joseph Driver, Matthew Ingham, Suthee Rapisuwon, Jennifer Wargo, Craig L. Slinguff, Evan Z. Macosco, Fei Chen, Richard Carvajal, Michael B. Atkins, Michael A. Davies, Elham Azizi, Santiago J. Carmona, Hanina Hibshoosh, Peter D. Canoll, Jeffrey N. Bruce, Wenya L. Bi, Gary K. Schwartz, Benjamin Izar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 984.
https://doi.org/10.1158/1538-7445.AM2022-984
Published: 15 June 2022
View articletitled, Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis
Journal Articles

Abstract 1202: A repository of PDX histology images for exploring spatial heterogeneity and cancer dynamics

Brian S. White, Xingyi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Akshat M. Savaliya, Lacey E. Dobrolecki, John D. Landua, Matthew H. Bailey, Maihi Fujita, Kurt W. Evans, Bingliang Fang, Junya Fujimoto, Maria Gabriela Raso, Shidan Wang, Guanghua Xiao, Yang Xie, Sherri R. Davies, Ryan C. Fields, R Jay Mashl, Jacqueline L. Mudd, Yeqing Chen, Min Xiao, Xiaowei Xu, Melinda G. Hollingshead, Shahanawaz Jiwani, PDXNet Consortium, Yvonne A. Evrard, Tiffany A. Wallace, Jeffrey A. Moscow, James H. Doroshow, Nicholas Mitsiades, Salma Kaochar, Chong-xian Pan, Moon S. Chen, Luis G. Carvajal-Carmona, Alana L. Welm, Bryan E. Welm, Michael T. Lewis, Ramaswamy Govindan, Li Ding, Shunqiang Li, Meenhard Herlyn, Michael A. Davies, Jack A. Roth, Funda Meric-Bernstam, Carol J. Bult, Brandi Davis-Dusenbery, Dennis A. Dean, Jeffrey H. Chuang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1202.
https://doi.org/10.1158/1538-7445.AM2022-1202
Published: 15 June 2022
View articletitled, Abstract 1202: A repository of PDX histology images for exploring spatial heterogeneity and cancer dynamics
Journal Articles

Abstract CT039: Intratumoral CD40 agonist sotigalimab with pembrolizumab induces broad innate and adaptive immune activation in local and distant tumors in metastatic melanoma

Salah-Eddine Bentebibel, Daniel Johnson, Rodabe Amariae, Daniel McGrail, Srisuda Lecagoonporn, Cara Haymaker, Dzifa Duose, Khalida Wani, Houssein Safa, Isabella Claudia Glitza, Sapna Pradyuman Patel, Michael K. Wong, Hussein Tawbi, Jared Burks, Xiaodong Yang, Patrick Hwu, Cassian Yee, Michael A. Davies, Ravi Murthy, Chantale Bernatchez, Suhendan Ekmekcioglu, Adi Diab, Gregory Lizée
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT039.
https://doi.org/10.1158/1538-7445.AM2022-CT039
Published: 15 June 2022
View articletitled, Abstract CT039: Intratumoral CD40 agonist sotigalimab with pembrolizumab induces broad innate and adaptive immune activation in local and distant tumors in metastatic melanoma
Journal Articles

Abstract 2844: The role of oxidative phosphorylation (OXPHOS) in melanoma brain metastasis (MBM) formation and growth

Grant M. Fischer, Renato A. Guerrieri, Qianghua Hu, Fernando C. Carapeto, Aron Y. Joon, Vashisht Y. Gopal, Barbara Knighton, Wanleng Deng, Lauren E. Haydu, Jeffrey E. Gershenwald, Alexander J. Lazar, Michael T. Tetzlaff, Michael A. Davies
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2844.
https://doi.org/10.1158/1538-7445.AM2021-2844
Published: 01 July 2021
View articletitled, Abstract 2844: The role of oxidative phosphorylation (OXPHOS) in melanoma brain metastasis (MBM) formation and growth
Journal Articles

Abstract 40: Targeting SOX10-deficient cells to reduce resistance to targeted therapy in melanoma

Claudia Capparelli, Timothy J. Purwin, Manoela Tiago, Nicole Wilski, Danielle Pomante, McKenna Glasheen, Sheera Rosenbaum, Mai Q. Nguyen, Weijia Cai, Richard Zheng, Gaurav Kumar, Inna Chervoneva, Ayako Shimada, Adam E. Snook, Paolo Fortina, Xiaowei Xu, Kim Hookim, Edna Cukierman, Michael A. Davies, Meenhard Herlyn, Andrew E. Aplin
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 40.
https://doi.org/10.1158/1538-7445.AM2021-40
Published: 01 July 2021
View articletitled, Abstract 40: Targeting SOX10-deficient cells to reduce resistance to targeted therapy in melanoma
Journal Articles

Abstract LB208: Obesity is associated with lower tumor oxidative phosphorylation (OXPhos) in metastatic melanoma (MM)

Andrew W. Hahn, Mingchu Xu, Jun Li, Lauren E. Haydu, M.A. Wadud Khan, Tuba N. Gide, Alexander M. Menzies, Courtney W. Hudgens, Theodore S. Nowicki, Jeffrey E. Gershenwald, Antoni Ribas, Michael T. Tetzlaff, Alexander J. Lazar, James Willmott, Jennifer Wargo, Andrew Futreal, Jianhua Zhang, Michael A. Davies, Jennifer L. McQuade
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB208.
https://doi.org/10.1158/1538-7445.AM2021-LB208
Published: 01 July 2021
View articletitled, Abstract LB208: Obesity is associated with lower tumor oxidative phosphorylation (OXPhos) in metastatic melanoma (MM)
Journal Articles

Abstract IA05: Distinct immune and molecular features of melanoma brain metastases

Michael A. Davies
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): IA05.
https://doi.org/10.1158/1538-7445.MEL2019-IA05
Published: 02 October 2020
View articletitled, Abstract IA05: Distinct immune and molecular features of melanoma brain metastases
Journal Articles

Abstract A11: Prognostic model for disease-specific survival in anorectal melanoma

Priyadharsini Nagarajan, JIn Piao, Jing Ning, Laura E. Noordenbos, Jonathan L. Curry, Carlos A. Torres-Cabala, A. Hafeez Diwan, Phyu P. Aung, Doina Ivan, Merrick I. Ross, Richard E. Royal, Jennifer A. Wargo, Wei-Lien Wang, Rashmi Samdani, Alexander J. Lazar, Asif Rashid, Michael A. Davies, Victor G. Prieto, Jeffrey E. Gershenwald, Michael T. Tetzlaff
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): A11.
https://doi.org/10.1158/1538-7445.MEL2019-A11
Published: 02 October 2020
View articletitled, Abstract A11: Prognostic model for disease-specific survival in anorectal melanoma
Journal Articles

Abstract A05: Molecular, immunologic, metabolic, and radiomic associations of oxidative phosphorylation (OXPHOS) in melanoma brain metastases (MBMs)

Grant M. Fischer, Aikaterini Kotrotsou, Sara Ahmed, Pilar O’Neal, Iman Sahnoune, Y.N. Vashisht Gopal, Courtney Hudgens, Barbara Knighton, Rivka Colen, Michael T. Tetzlaff, Michael A. Davies
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): A05.
https://doi.org/10.1158/1538-7445.MEL2019-A05
Published: 02 October 2020
View articletitled, Abstract A05: Molecular, immunologic, metabolic, and radiomic associations of oxidative phosphorylation (OXPHOS) in melanoma brain metastases (MBMs)
Journal Articles

Abstract PR02: Melanoma evolves complete immunotherapy resistance through acquisition of a hypermetabolic phenotype

Ashvin R. Jaiswal, Arthur J. Liu, Shivanand Pudakalakatti, Prasanta Dutta, Priyamvada Jayaprakash, Todd Bartkowiak, Casey Ager, Zhiqiang Wang, Alex Reuben, Zachary Cooper, Cristina Ivan, Zhenlin Ju, Felix Nwajei, Jing Wang, Michael A. Davies, R. Eric Davis, Jennifer A. Wargo, Pratip K. Bhattacharya, David S. Hong, Michael A. Curran
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): PR02.
https://doi.org/10.1158/1538-7445.MEL2019-PR02
Published: 02 October 2020
View articletitled, Abstract PR02: Melanoma evolves complete immunotherapy resistance through acquisition of a hypermetabolic phenotype
Journal Articles

Abstract 5704: Pan-cancer genomic characterization of patient-matched primary, extracranial, and brain metastases

Olivia W. Lee, Akash Mitra, Won-Chul Lee, Kazutaka Fukumura, Hannah Beird, Miles Andrews, Grant Fischer, John N. Weinstein, Michael A. Davies, Jason Huse, P. Andrew Futreal
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5704.
https://doi.org/10.1158/1538-7445.AM2020-5704
Published: 15 August 2020
View articletitled, Abstract 5704: Pan-cancer genomic characterization of patient-matched primary, extracranial, and brain metastases