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Journal Articles

Abstract 4689: Poly ADP ribose polymerase inhibitors potentiate proton therapy end-of-range relative biological effective dose by increasing replication stress

Yiqun Han, Qin Zhou, Anna Olson, Cameron M. Callaghan, Bin Chen, Nicholas B. Remmes, Meng Xu Welliver, Zheming Wu, Daniel K. Ebner, Jake A. Kloeber, Zhenkun Lou, Robert W. Mutter
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4689.
https://doi.org/10.1158/1538-7445.AM2025-4689
Published: 21 April 2025
View articletitled, Abstract 4689: Poly ADP ribose polymerase inhibitors potentiate proton therapy end-of-range relative biological effective dose by increasing replication stress
Journal Articles

Abstract 887: Fast, interactive, AI-assisted 3D lung tumour segmentation

Mayank Patwari, Yi Wei, Meng Xu, Zhenning Zhang, Konstantinos Sidiropoulos, Balaji Selvaraj, Georgia Hughes, Nadine Garibli, Kamsiriochukwu Ojiako, Mohan Lella, Leon Fedden, James Parkin, Michael Parker, Shaneil Patel, Qin Li, Kedar Patwardhan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 887.
https://doi.org/10.1158/1538-7445.AM2024-887
Published: 22 March 2024
View articletitled, Abstract 887: Fast, interactive, AI-assisted 3D lung tumour segmentation
Journal Articles

Abstract 5427: Improving non-small cell lung cancer segmentation on a challenging dataset

Yi Wei, Balaji Selvaraj, Mayank Patwari, Qin Li, Meng Xu, Konstantinos Sidiropoulos, Zhenning Zhang, Leon Fedden, Anant Madabhushi, Mohammadhadi Khorrami, Vidya Sankar Viswanathan, Amit Gupta
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5427.
https://doi.org/10.1158/1538-7445.AM2023-5427
Published: 04 April 2023
View articletitled, Abstract 5427: Improving non-small cell lung cancer segmentation on a challenging dataset
Journal Articles

Abstract 2093: PEGylated IL-2 with enhanced anti-tumor efficacy and safety profile

Yuntao Song, Hui Li, Wei Zhang, Dayan Fu, Meng Xu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2093.
https://doi.org/10.1158/1538-7445.AM2022-2093
Published: 15 June 2022
View articletitled, Abstract 2093: PEGylated IL-2 with enhanced anti-tumor efficacy and safety profile
Journal Articles

Abstract P1-02-17: Artificial intelligence-based whole slide scoring of nuclear breast cancer IHC markers Ki67, ER, and PR matches performance of manual clinical scoring

Monesh Kapadia, Mehrnoush Khojasteh, Margarita Kouzova, Carol Jones, Xiao-Meng Xu, Matthew T. Olson, Sarah Gladden, Nancy Sapanara, Shalini Singh, Chen Chun Chen, Isaac Bai, Jim Ranger-Moore, Landon J. Inge, Uday Kurkure, Ipshita Bhattacharya, Margaret Zhao, Karel Zuiderveld, Chandana Chintakindi, Bryan Lopez, Christoph Guetter
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-02-17.
https://doi.org/10.1158/1538-7445.SABCS21-P1-02-17
Published: 15 February 2022
View articletitled, Abstract P1-02-17: Artificial intelligence-based whole slide scoring of nuclear breast cancer IHC markers Ki67, ER, and PR matches performance of manual clinical scoring
Journal Articles

Abstract 293: Heat shock factor 1 directly suppresses AMP-activated protein kinase to promote tumorigenesis

Kuo-Hui Su, Siyuan Dai, Zijian Tang, Meng Xu, Chengkai Dai
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 293.
https://doi.org/10.1158/1538-7445.AM2020-293
Published: 15 August 2020
View articletitled, Abstract 293: Heat shock factor 1 directly suppresses AMP-activated protein kinase to promote tumorigenesis
Journal Articles

Abstract 4508: Modulating the release rate of polyethylene glycol (PEG) polymers from interleukin-2 (IL-2) PEG conjugates to optimize anti-tumor efficacy

Hui Li, Yuntao Song, Haiping Zhou, Chuan Liao, Meng Xu, Chuang Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4508.
https://doi.org/10.1158/1538-7445.AM2020-4508
Published: 15 August 2020
View articletitled, Abstract 4508: Modulating the release rate of polyethylene glycol (PEG) polymers from interleukin-2 (IL-2) PEG conjugates to optimize anti-tumor efficacy
Journal Articles

SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial–Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model

Meng Xu, Jingxiao Wang, Zhong Xu, Rong Li, Pan Wang, Runze Shang, Antonio Cigliano, Silvia Ribback, Antonio Solinas, Giovanni Mario Pes, Katja Evert, Haichuan Wang, Xinhua Song, Shu Zhang, Li Che, Rosa Maria Pascale, Diego Francesco Calvisi, Qingguang Liu, Xin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5563–5574.
https://doi.org/10.1158/0008-5472.CAN-18-3750
Published: 01 November 2019
View articletitled, SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial–Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model
Open the PDF for SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial–Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model in another window
Includes: Supplementary data
Journal Articles

Abstract 3180: Chemotherapeutical agent triggers transient resistance of cancer cells by promoting ABCB1 intercellular transfer

Xiaokun Wang, Dongjuan Qiao, Likun Chen, Liyan Huang, Meng Xu, Zhen Chen, Fang Wang, Zhesheng Chen, Musheng Zeng, Li-Wu Fu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3180.
https://doi.org/10.1158/1538-7445.AM2017-3180
Published: 01 July 2017
View articletitled, Abstract 3180: Chemotherapeutical agent triggers transient resistance of cancer cells by promoting ABCB1 intercellular transfer
Journal Articles

Abstract 854: Inhibition of PRMT5 results in radiosensitization in lung cancer cell lines

Smitha Sharma, X Wu, P Smith, N Denko, C Li, H Lai, F Yan, K Shilo, A Chakravarti, S Sif, R Baiocchi, G Otterson, Meng Xu-Welliver
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 854.
https://doi.org/10.1158/1538-7445.AM2014-854
Published: 01 October 2014
View articletitled, Abstract 854: Inhibition of PRMT5 results in radiosensitization in lung cancer cell lines
Journal Articles

Abstract 2189: Inhibition of PIN1 suppresses tumorigenicity of EBV-associated NPC.

Meng Xu, Chit Chow, Chartia Ching-Mei Cheung, Chi-Man Tsang, Samantha Wei-Man Lun, Jessie Wai-Fung Yuen, Grace Tin-Yun Chung, Sah-Wah Tsao, Ka Fai To, Kwok Wai Lo
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2189.
https://doi.org/10.1158/1538-7445.AM2013-2189
Published: 15 April 2013
View articletitled, Abstract 2189: Inhibition of PIN1 suppresses tumorigenicity of EBV-associated NPC.
Journal Articles

Abstract 2513: Molecular dissection of cell death mechanisms following ionizing radiation in vitro and in vivo

Meng Xu Welliver, Lori S. Hart, Jiangbin Ye, Chao Lu, Rosemarie Mick, Mei Kong, Dara Ditsworth, Anna Mesina, Fangping Zhao, Jennifer L. Guerriero, Weixing Zong, Constantinos Koumenis, Craig B. Thompson
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2513.
https://doi.org/10.1158/1538-7445.AM2011-2513
Published: 15 April 2011
View articletitled, Abstract 2513: Molecular dissection of cell death mechanisms following ionizing radiation in vitro and in vivo
Journal Articles

Inactivation and Degradation of O 6-Alkylguanine-DNA Alkyltransferase after Reaction with Nitric Oxide

Liping Liu, Meng Xu-Welliver, Sreenivas Kanugula, Anthony E. Pegg
Journal: Cancer Research
Cancer Res (2002) 62 (11): 3037–3043.
Published: 01 June 2002
View articletitled, Inactivation and Degradation of O 6-Alkylguanine-DNA Alkyltransferase after Reaction with Nitric Oxide
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Journal Articles

Effect of O6-Benzylguanine on Alkylating Agent-induced Toxicity and Mutagenicity in Chinese Hamster Ovary Cells Expressing Wild-Type and Mutant O6-Alkylguanine-DNA Alkyltransferases

Yingna Cai, Michael H. Wu, Meng Xu-Welliver, Anthony E. Pegg, Susan M. Ludeman, M. Eileen Dolan
Journal: Cancer Research
Cancer Res (2000) 60 (19): 5464–5469.
Published: 01 October 2000
View articletitled, Effect of O6-Benzylguanine on Alkylating Agent-induced Toxicity and Mutagenicity in Chinese Hamster Ovary Cells Expressing Wild-Type and Mutant O6-Alkylguanine-DNA Alkyltransferases
Open the PDF for Effect of O6-Benzylguanine on Alkylating Agent-induced Toxicity and Mutagenicity in Chinese Hamster Ovary Cells Expressing Wild-Type and Mutant O6-Alkylguanine-DNA Alkyltransferases in another window
Journal Articles

Direct Reversal of DNA Damage by Mutant Methyltransferase Protein Protects Mice against Dose-intensified Chemotherapy and Leads to in Vivo Selection of Hematopoietic Stem Cells

Susanne Ragg, Meng Xu-Welliver, Jeff Bailey, Maria D’Souza, Ryan Cooper, Saurabh Chandra, Roopa Seshadri, Anthony E. Pegg, David A. Williams
Journal: Cancer Research
Cancer Res (2000) 60 (18): 5187–5195.
Published: 01 September 2000
View articletitled, Direct Reversal of DNA Damage by Mutant Methyltransferase Protein Protects Mice against Dose-intensified Chemotherapy and Leads to in Vivo Selection of Hematopoietic Stem Cells
Open the PDF for Direct Reversal of DNA Damage by Mutant Methyltransferase Protein Protects Mice against Dose-intensified Chemotherapy and Leads to in Vivo Selection of Hematopoietic Stem Cells in another window
Journal Articles

Alteration of the Conserved Residue Tyrosine-158 to Histidine Renders Human O6-Alkylguanine-DNA Alkyltransferase Insensitive to the Inhibitor O6-Benzylguanine

Meng Xu-Welliver, José Leitão, Sreenivas Kanugula, Anthony E. Pegg
Journal: Cancer Research
Cancer Res (1999) 59 (7): 1514–1519.
Published: 01 April 1999
View articletitled, Alteration of the Conserved Residue Tyrosine-158 to Histidine Renders Human O6-Alkylguanine-DNA Alkyltransferase Insensitive to the Inhibitor O6-Benzylguanine
Open the PDF for Alteration of the Conserved Residue Tyrosine-158 to Histidine Renders Human O6-Alkylguanine-DNA Alkyltransferase Insensitive to the Inhibitor O6-Benzylguanine in another window
Journal Articles

Isolation of Human O6-Alkylguanine-DNA Alkyltransferase Mutants Highly Resistant to Inactivation by O6-Benzylguanine

Meng Xu-Welliver, Sreenivas Kanugula, Anthony E. Pegg
Journal: Cancer Research
Cancer Res (1998) 58 (9): 1936–1945.
Published: 01 May 1998
View articletitled, Isolation of Human O6-Alkylguanine-DNA Alkyltransferase Mutants Highly Resistant to Inactivation by O6-Benzylguanine
Open the PDF for Isolation of Human O6-Alkylguanine-DNA Alkyltransferase Mutants Highly Resistant to Inactivation by O6-Benzylguanine in another window