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Melvin J. Yu
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Journal Articles

Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for In vivo Efficacy under Intermittent Dosing Conditions

Murray J. Towle, Kathleen A. Salvato, Bruce F. Wels, Kimberley K. Aalfs, Wanjun Zheng, Boris M. Seletsky, Xiaojie Zhu, Bryan M. Lewis, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2011) 71 (2): 496–505.
https://doi.org/10.1158/0008-5472.CAN-10-1874
Published: 13 January 2011
View article titled, Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for <em>In vivo</em> Efficacy under Intermittent Dosing Conditions
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Includes: Supplementary data
Journal Articles

Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng, Takanori Kawamura, Karen TenDyke, Diana Liu, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5760–5766.
https://doi.org/10.1158/0008-5472.CAN-04-1169
Published: 16 August 2004
View article titled, Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389
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Journal Articles

In Vitro and In Vivo Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B

Murray J. Towle, Kathleen A. Salvato, Jacqueline Budrow, Bruce F. Wels, Galina Kuznetsov, Kimberley K. Aalfs, Susan Welsh, Wanjun Zheng, Boris M. Seletsky, Monica H. Palme, Gregory J. Habgood, Lori A. Singer, Lucian V. DiPietro, Yuan Wang, Jack J. Chen, David A. Quincy, Ashley Davis, Kentaro Yoshimatsu, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2001) 61 (3): 1013–1021.
Published: 02 February 2001
View article titled, <em>In Vitro</em> and <em>In Vivo</em> Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B
Open the PDF for <em>In Vitro</em> and <em>In Vivo</em> Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B in another window