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Meike Vogler
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Journal Articles

NRAS-Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3K α

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Nadezda Dolgikh, Manuela Hugle, Meike Vogler, Simone Fulda
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2000–2013.
https://doi.org/10.1158/0008-5472.CAN-17-1737
Published: 12 April 2018
View articletitled, NRAS-Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3K α
Open the PDF for NRAS-Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3K α in another window
Includes: Supplementary data
Journal Articles

Abstract 2911: Small molecule XIAP inhibitors sensitize acute leukemia cells for TRAIL- or chemotherapy-induced apoptosis, overcome Bcl-2-mediated resistance and reduce leukemic burden in vivo in NOD/SCID mice

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Melanie Fakler, Sandra Löder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2911.
https://doi.org/10.1158/1538-7445.AM10-2911
Published: 15 April 2010
View articletitled, Abstract 2911: Small molecule XIAP inhibitors sensitize acute leukemia cells for TRAIL- or chemotherapy-induced apoptosis, overcome Bcl-2-mediated resistance and reduce leukemic burden in vivo in NOD/SCID mice
Journal Articles

Abstract #2039: Targeting XIAP overcomes Bcl-2-imposed resistance of pancreatic carcinoma towards TRAIL in vitro and in vivo

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Dominic Stadel, Meike Vogler, Tobias Haas, Henning Walczak, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2039.
Published: 01 May 2009
View articletitled, Abstract #2039: Targeting XIAP overcomes Bcl-2-imposed resistance of pancreatic carcinoma towards TRAIL in vitro and in vivo
Journal Articles

Abstract #2781: XIAP inhibitors prime childhood acute leukemia cells for TRAIL-induced apoptosis, overcome Bcl-2-mediated resistance and exert anti-leukemic activity in a NOD/SCID mouse model of childhood acute leukemia

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Melanie Fakler, Sandra Loeder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2781.
Published: 01 May 2009
View articletitled, Abstract #2781: XIAP inhibitors prime childhood acute leukemia cells for TRAIL-induced apoptosis, overcome Bcl-2-mediated resistance and exert anti-leukemic activity in a NOD/SCID mouse model of childhood acute leukemia
Journal Articles

Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Möller, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2425–2434.
https://doi.org/10.1158/0008-5472.CAN-08-2436
Published: 17 March 2009
View articletitled, Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma
Open the PDF for Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma in another window
Includes: Supplementary data
Journal Articles

Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7956–7965.
https://doi.org/10.1158/0008-5472.CAN-08-1296
Published: 30 September 2008
View articletitled, Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo
Open the PDF for Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo in another window
Includes: Supplementary data
Journal Articles

Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer

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Meike Vogler, Henning Walczak, Dominic Stadel, Tobias Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Moeller, Juergen Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2550.
Published: 01 May 2008
View articletitled, Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer
Journal Articles

Small molecule XIAP inhibitors prime childhood acute leukemia cells for TRAIL- or chemotherapy-induced apoptosis and overcome Bcl-2-mediated resistance

Free
Melanie Fakler, Meike Vogler, Sandra Loder, Irmela Jeremias, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2989.
Published: 01 May 2008
View articletitled, Small molecule XIAP inhibitors prime childhood acute leukemia cells for TRAIL- or chemotherapy-induced apoptosis and overcome Bcl-2-mediated resistance
Journal Articles

Targeting XIAP overcomes apoptosis resistance of pancreatic carcinoma and synergizes with TRAIL to suppress tumor growth and invasion in vivo

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Meike Vogler, Cornelia Hasel, Peter Moeller, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4869.
Published: 01 May 2007
View articletitled, Targeting XIAP overcomes apoptosis resistance of pancreatic carcinoma and synergizes with TRAIL to suppress tumor growth and invasion in vivo
Journal Articles

Targeting XIAP overcomes apoptosis resistance of pancreatic carcinoma cells in vitro and suppresses tumor growth and invasion in vivo

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Meike Vogler, Katharina Dürr, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1142.
Published: 15 April 2006
View articletitled, Targeting XIAP overcomes apoptosis resistance of pancreatic carcinoma cells in vitro and suppresses tumor growth and invasion in vivo
Journal Articles

Sensitization for γ-Irradiation–Induced Apoptosis by Second Mitochondria-Derived Activator of Caspase

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Stavros Giagkousiklidis, Meike Vogler, Mike-Andrew Westhoff, Hubert Kasperczyk, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10502–10513.
https://doi.org/10.1158/0008-5472.CAN-05-0866
Published: 15 November 2005
View articletitled, Sensitization for γ-Irradiation–Induced Apoptosis by Second Mitochondria-Derived Activator of Caspase
Open the PDF for Sensitization for γ-Irradiation–Induced Apoptosis by Second Mitochondria-Derived Activator of Caspase in another window
Includes: Supplementary data
Journal Articles

Sensitization for gamma-irradiation-induced apoptosis by Smac agonists

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Stavros Giagkousiklidis, Meike Vogler, Hubert Kasperczyk, Andrew Westhoff, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 390.
Published: 01 May 2005
View articletitled, Sensitization for gamma-irradiation-induced apoptosis by Smac agonists
Journal Articles

Inhibition of tumor cell growth: a novel function of Smac contributing to its antitumor activity

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Meike Vogler, Stavros Giagkousiklidis, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 196.
Published: 01 May 2005
View articletitled, Inhibition of tumor cell growth: a novel function of Smac contributing to its antitumor activity