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Journal Articles

Abstract 1219: Establishment and characterization of amitrole-induced mouse thyroid adenoma-derived cell lines

Yo-Taro Shirai, Nobuo Hoshi, Huaitian Liu, Maxwell P. Lee, Shioko Kimura

Cancer Res (2023) 83 (7_Supplement): 1219.

https://doi.org/10.1158/1538-7445.AM2023-1219

Published: 04 April 2023

View article titled, Abstract 1219: Establishment and characterization of amitrole-induced mouse thyroid adenoma-derived cell lines

Journal Articles

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Farid Rashidi Mehrabadi, Salem Malikić, Kerrie L. Marie, Eva Pérez-Guijarro, Erfan Sadeqi Azer, Howard H. Yang, Can Kızılkale, Charli Gruen, Huaitian Liu, Christina Marcelus, Aydın Buluç, Funda Ergün, Maxwell P. Lee, Glenn Merlino, Chi-Ping Day, S. Cenk Sahinalp

Cancer Res (2021) 81 (13_Supplement): LB019.

https://doi.org/10.1158/1538-7445.AM2021-LB019

Published: 01 July 2021

View article titled, Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Journal Articles

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Jae Young So, Nicolas Skrypek, Howard H. Yang, Anand S. Merchant, George W. Nelson, Wei-Dong Chen, Hiroki Ishii, Jennifer M. Chen, Gangqing Hu, Bhagelu R. Achyut, Esther C. Yoon, Liying Han, Chuanshu Huang, Margaret C. Cam, Keji Zhao, Maxwell P. Lee, Li Yang

Cancer Res (2020) 80 (12): 2612–2627.

https://doi.org/10.1158/0008-5472.CAN-19-3339

Published: 15 June 2020

View article titled, Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Includes: Supplementary data

Journal Articles

Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell–Autonomous Suppressor Role

Nellie Moshkovich, Humberto J. Ochoa, Binwu Tang, Howard H. Yang, Yuan Yang, Jing Huang, Maxwell P. Lee, Lalage M. Wakefield

Cancer Res (2020) 80 (11): 2125–2137.

https://doi.org/10.1158/0008-5472.CAN-19-3018

Published: 02 June 2020

View article titled, Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell–Autonomous Suppressor Role

Includes: Supplementary data

Journal Articles

Abstract 3676: Novel tumor suppressive role of Peptidylarginine deiminase IV involving cancer stem cell regulation in breast cancer models

Humberto J. Ochoa, Nellie Moshkovich, Binwu Tang, Howard H. Yang, Maxwell P. Lee, Lalage M. Wakefield

Cancer Res (2019) 79 (13_Supplement): 3676.

https://doi.org/10.1158/1538-7445.AM2019-3676

Published: 01 July 2019

View article titled, Abstract 3676: Novel tumor suppressive role of Peptidylarginine deiminase IV involving cancer stem cell regulation in breast cancer models

Journal Articles

Abstract 1768: An anti-TGF-β1/2 antibody that spares TGF-β3 retains full anti-tumor efficacy and generates an improved metabolic profile

Yu-an Yang, Srividya Vasu, Howard Yang, Maxwell P. Lee, Sushil Rane, Amer M. Mirza, Lalage M. Wakefield

Cancer Res (2018) 78 (13_Supplement): 1768.

https://doi.org/10.1158/1538-7445.AM2018-1768

Published: 01 July 2018

View article titled, Abstract 1768: An anti-TGF-β1/2 antibody that spares TGF-β3 retains full anti-tumor efficacy and generates an improved metabolic profile

Journal Articles

Abstract 1846: Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis therapies to target breast cancer metastasis

Yu-an Yang, Howard Yang, Ying Hu, Peter Watson, Huaitian Liu, Thomas R. Geiger, Miriam R. Anver, Diana Haines, Philip Martin, Maxwell P. Lee, Kent W. Hunter, Lalage M. Wakefield

Cancer Res (2017) 77 (13_Supplement): 1846.

https://doi.org/10.1158/1538-7445.AM2017-1846

Published: 01 July 2017

View article titled, Abstract 1846: Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis therapies to target breast cancer metastasis

Journal Articles

Abstract 2561: Integrated analysis of ESCC tumor/normal tissues and patient blood samples using expression, genotypes and DNA somatic change data

Howard H. Yang, Hua Su, Huaitian Liu, Nan Hu, Chaoyu Wang, Lemin Wang, Ti Ding, Carol Giffen, Alisa M. Goldstein, Philip R. Taylor, Maxwell P. Lee

Cancer Res (2016) 76 (14_Supplement): 2561.

https://doi.org/10.1158/1538-7445.AM2016-2561

Published: 15 July 2016

View article titled, Abstract 2561: Integrated analysis of ESCC tumor/normal tissues and patient blood samples using expression, genotypes and DNA somatic change data

Journal Articles

Abstract IA21: An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes

Kent W. Hunter, Ling Bai, Howard H. Yang, Ying Hu, Anjali Shukla, Ngoc-Han Ha, Anthony Doran, Farhoud Faraji, Natalie Goldberger, Maxwell P. Lee, Thomas Keane

Cancer Res (2016) 76 (7_Supplement): IA21.

https://doi.org/10.1158/1538-7445.TUMMET15-IA21

Published: 26 May 2016

View article titled, Abstract IA21: An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes

Journal Articles

Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer

Cancer Res (2016) 76 (7): 1714–1723.

https://doi.org/10.1158/0008-5472.CAN-15-0338

Published: 31 March 2016

View article titled, Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer

Includes: Supplementary data

Journal Articles

Abstract 2244: Functional interactions between estrogen-related-receptor β (ESRRB) and transforming growth factor-beta (TGF-β) in the regulation of breast cancer stem cell dynamics

Nellie Moshkovich, Misako Sato, Binwu Tang, Yu-an Yang, Kathleen C. Flanders, Mitsutaka Kadota, Howard Yang, Maxwell P. Lee, Lalage M. Wakefield

Cancer Res (2015) 75 (15_Supplement): 2244.

https://doi.org/10.1158/1538-7445.AM2015-2244

Published: 01 August 2015

View article titled, Abstract 2244: Functional interactions between estrogen-related-receptor β (ESRRB) and transforming growth factor-beta (TGF-β) in the regulation of breast cancer stem cell dynamics

Journal Articles

Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Howard H. Yang, Huaitian Liu, Ronald Lubet, Clinton J. Grubbs, Holly Nicastro, Maxwell P. Lee

Cancer Res (2015) 75 (15_Supplement): 896.

https://doi.org/10.1158/1538-7445.AM2015-896

Published: 01 August 2015

View article titled, Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Journal Articles

Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Cancer Res (2015) 75 (15_Supplement): 4622.

https://doi.org/10.1158/1538-7445.AM2015-4622

Published: 01 August 2015

View article titled, Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Journal Articles

Abstract 4125: Robust feature selection and gene committee predictor for breast cancer patient survival prediction

Howard H. Yang, Maxwell P. Lee

Cancer Res (2014) 74 (19_Supplement): 4125.

https://doi.org/10.1158/1538-7445.AM2014-4125

Published: 01 October 2014

View article titled, Abstract 4125: Robust feature selection and gene committee predictor for breast cancer patient survival prediction

Journal Articles

Abstract 5368: Epigenetic changes in breast cancer cells associated with acquired Tamoxifen resistance.

Kristin E. Williams, Douglas L. Anderton, Maxwell P. Lee, Brian T. Pentecost, Kathleen F. Arcaro

Cancer Res (2013) 73 (8_Supplement): 5368.

https://doi.org/10.1158/1538-7445.AM2013-5368

Published: 15 April 2013

View article titled, Abstract 5368: Epigenetic changes in breast cancer cells associated with acquired Tamoxifen resistance.

Journal Articles

Abstract A7: Roles of miRNAs in the switch of TGF-β from tumor suppressor to pro-oncogenic factor in cancer progression

Yoshiko Nagano, Maxwell P. Lee, Lalage M. Wakefield

Cancer Res (2012) 72 (2_Supplement): A7.

https://doi.org/10.1158/1538-7445.NONRNA12-A7

Published: 03 April 2013

View article titled, Abstract A7: Roles of miRNAs in the switch of TGF-β from tumor suppressor to pro-oncogenic factor in cancer progression

Journal Articles

Abstract 4527: Pharmacodynamic and pathway analysis of three presumed inhibitors of poly (ADP-ribose) polymerase: ABT-888, AZD2281, and BSI201

Jiuping Ji, Maxwell P. Lee, Mitsutaka Kadota, Yiping Zhang, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow

Cancer Res (2011) 71 (8_Supplement): 4527.

https://doi.org/10.1158/1538-7445.AM2011-4527

Published: 15 April 2011

View article titled, Abstract 4527: Pharmacodynamic and pathway analysis of three presumed inhibitors of poly (ADP-ribose) polymerase: ABT-888, AZD2281, and BSI201

Journal Articles

Abstract 4971: Transcriptome analysis and the identification of novel somatic mutations in breast cancer by the next-generation sequencing

Maxwell P. Lee, Mitsutaka Kadota

Cancer Res (2011) 71 (8_Supplement): 4971.

https://doi.org/10.1158/1538-7445.AM2011-4971

Published: 15 April 2011

View article titled, Abstract 4971: Transcriptome analysis and the identification of novel somatic mutations in breast cancer by the next-generation sequencing

Journal Articles

Identification of Novel Gene Amplifications in Breast Cancer and Coexistence of Gene Amplification with an Activating Mutation of PIK3CA

Mitsutaka Kadota, Misako Sato, Beverly Duncan, Akira Ooshima, Howard H. Yang, Natacha Diaz-Meyer, Sheryl Gere, Shun-Ichiro Kageyama, Junya Fukuoka, Takuya Nagata, Kazuhiro Tsukada, Barbara K. Dunn, Lalage M. Wakefield, Maxwell P. Lee

Cancer Res (2009) 69 (18): 7357–7365.

https://doi.org/10.1158/0008-5472.CAN-09-0064

Published: 14 September 2009

View article titled, Identification of Novel Gene Amplifications in Breast Cancer and Coexistence of Gene Amplification with an Activating Mutation of <em>PIK3CA</em>

Includes: Supplementary data

Journal Articles

Genomic Characterization of Esophageal Squamous Cell Carcinoma from a High-Risk Population in China

Nan Hu, Chaoyu Wang, David Ng, Robert Clifford, Howard H. Yang, Ze-Zhong Tang, Quan-Hong Wang, Xiao-You Han, Carol Giffen, Alisa M. Goldstein, Philip R. Taylor, Maxwell P. Lee

Cancer Res (2009) 69 (14): 5908–5917.

https://doi.org/10.1158/0008-5472.CAN-08-4622

Published: 15 July 2009

View article titled, Genomic Characterization of Esophageal Squamous Cell Carcinoma from a High-Risk Population in China

Includes: Supplementary data

NARROW

Abstract 1219: Establishment and characterization of amitrole-induced mouse thyroid adenoma-derived cell lines

Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell–Autonomous Suppressor Role

Abstract 3676: Novel tumor suppressive role of Peptidylarginine deiminase IV involving cancer stem cell regulation in breast cancer models

Abstract 1768: An anti-TGF-β1/2 antibody that spares TGF-β3 retains full anti-tumor efficacy and generates an improved metabolic profile

Abstract 1846: Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis therapies to target breast cancer metastasis

Abstract 2561: Integrated analysis of ESCC tumor/normal tissues and patient blood samples using expression, genotypes and DNA somatic change data

Abstract IA21: An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes

Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer

Abstract 2244: Functional interactions between estrogen-related-receptor β (ESRRB) and transforming growth factor-beta (TGF-β) in the regulation of breast cancer stem cell dynamics

Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Abstract 4125: Robust feature selection and gene committee predictor for breast cancer patient survival prediction

Abstract 5368: Epigenetic changes in breast cancer cells associated with acquired Tamoxifen resistance.

Abstract A7: Roles of miRNAs in the switch of TGF-β from tumor suppressor to pro-oncogenic factor in cancer progression

Abstract 4527: Pharmacodynamic and pathway analysis of three presumed inhibitors of poly (ADP-ribose) polymerase: ABT-888, AZD2281, and BSI201

Abstract 4971: Transcriptome analysis and the identification of novel somatic mutations in breast cancer by the next-generation sequencing

Identification of Novel Gene Amplifications in Breast Cancer and Coexistence of Gene Amplification with an Activating Mutation of PIK3CA

Genomic Characterization of Esophageal Squamous Cell Carcinoma from a High-Risk Population in China

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