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Journal Articles

Abstract LB049: Isoharpontigenin inhibits migration and invasion of lung cancer cells through MEG3/EGFR pathway

Sophia Shi, Zhuo Zhang, Jingxia Li, Huailu Tu, Max Costa
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB049.
https://doi.org/10.1158/1538-7445.AM2024-LB049
Published: 05 April 2024
View articletitled, Abstract LB049: Isoharpontigenin inhibits migration and invasion of lung cancer cells through MEG3/EGFR pathway
Journal Articles

Abstract 324: Nickel exposure alters extracellular vesicles biogenesis to carry NUPR1 and mediate cancer progression

Shan Liu, Angelica Ortiz, Juan Iovanna, Max Costa
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 324.
https://doi.org/10.1158/1538-7445.AM2023-324
Published: 04 April 2023
View articletitled, Abstract 324: Nickel exposure alters extracellular vesicles biogenesis to carry NUPR1 and mediate cancer progression
Journal Articles

Abstract 5993: Inhibition of isorhapontigenin on migration and invasion of bladder cancer cells depends on Sestrin 2 and Beclin 1

Zhuo Zhang, Jingxia Li, Huailu Tu, Max Costa
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5993.
https://doi.org/10.1158/1538-7445.AM2022-5993
Published: 15 June 2022
View articletitled, Abstract 5993: Inhibition of isorhapontigenin on migration and invasion of bladder cancer cells depends on Sestrin 2 and Beclin 1
Journal Articles

Abstract 228: Depletion of stem-loop binding protein and elevation of polyadenylation of histone 3.1 contribute to malignant cell transformation induced by bisphenol A

Arul Veerappan, Zhou Zhang, Max Costa
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 228.
https://doi.org/10.1158/1538-7445.AM2022-228
Published: 15 June 2022
View articletitled, Abstract 228: Depletion of stem-loop binding protein and elevation of polyadenylation of histone 3.1 contribute to malignant cell transformation induced by bisphenol A
Journal Articles

Abstract 4403: Regulation of SATB2 via miR-31 in Ni-induced malignant cell transformation

Qiao Yi Chen, Yusha Zhu, Ashley Jordan, Jinquan Li, Hong Sun, Thomas Kluz, Max Costa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4403.
https://doi.org/10.1158/1538-7445.AM2019-4403
Published: 01 July 2019
View articletitled, Abstract 4403: Regulation of SATB2 via miR-31 in Ni-induced malignant cell transformation
Journal Articles

Abstract 356: Polyadenyaltion of canonical histone mRNA: A potential mechanism of arsenic-induced carcinogenesis

Qiao Yi Chen, Danqi Chen, Thomas Kluz, Feng Wu, Yusha Zhu, Thomas Des Marais, Jinquan Li, Xiaoru Zhang, Ashley Jordan, Hong Sun, Chunyuan Jin, Max Costa
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 356.
https://doi.org/10.1158/1538-7445.AM2018-356
Published: 01 July 2018
View articletitled, Abstract 356: Polyadenyaltion of canonical histone mRNA: A potential mechanism of arsenic-induced carcinogenesis
Journal Articles

Abstract 1480: Overexpression of histone H3.1 induced cell malignant transformation and mutation of H3.1 C96/110A further induced chromatin instability

Yusha Zhu, Hong Sun, Max Costa
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1480.
https://doi.org/10.1158/1538-7445.AM2018-1480
Published: 01 July 2018
View articletitled, Abstract 1480: Overexpression of histone H3.1 induced cell malignant transformation and mutation of H3.1 C96/110A further induced chromatin instability
Journal Articles

Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway

Yusha Zhu, Anthony Murphy, Thomas Kluz, Bo Li, Max Costa, Chuanshu Huang, Hong Sun
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5857.
https://doi.org/10.1158/1538-7445.AM2018-5857
Published: 01 July 2018
View articletitled, Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway
Journal Articles

Abstract 4537: Hexavalent chromium induces H4K16 hypoacetylation by NUPR1-mediated inactivation of histone acetyltransferase hMOF

Qiao Yi Chen, Xiaoru Zhang, Thomas Kluz, Max Costa, Hong Sun
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4537.
https://doi.org/10.1158/1538-7445.AM2016-4537
Published: 15 July 2016
View articletitled, Abstract 4537: Hexavalent chromium induces H4K16 hypoacetylation by NUPR1-mediated inactivation of histone acetyltransferase hMOF
Journal Articles

Abstract 3590: Depleted uranium-induced leukemia: Epigenetic and genetic changes.

Alexandra C. Miller, Hailey Clancy, Thomas Kluz, Stuart Cohen, Rafael Rivas, Karvelisse Miller, Max Costa
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3590.
https://doi.org/10.1158/1538-7445.AM2013-3590
Published: 15 April 2013
View articletitled, Abstract 3590: Depleted uranium-induced leukemia: Epigenetic and genetic changes.
Journal Articles

Abstract 72: Gene-specific H3K4 trimethylation changes in healthy human subjects exposed to carcinogenic metal components of air particles

Laura Cantone, Thomas Kluz, Letizia Tarantini, Matteo Bonzini, Barbara Marinelli, Pier Alberto Bertazzi, Andrea Baccarelli, Max Costa
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 72.
https://doi.org/10.1158/1538-7445.AM2011-72
Published: 15 April 2011
View articletitled, Abstract 72: Gene-specific H3K4 trimethylation changes in healthy human subjects exposed to carcinogenic metal components of air particles
Journal Articles

Abstract 5548: Comparison of gene expression profile in chromate transformed BEAS-2B cells

Sun Hong, Harriet A. Clancy, Thomas Kluz, Jiri Zavadil, Max Costa
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5548.
https://doi.org/10.1158/1538-7445.AM2011-5548
Published: 15 April 2011
View articletitled, Abstract 5548: Comparison of gene expression profile in chromate transformed BEAS-2B cells
Journal Articles

Abstract 1996: Chronic arsenic exposure and changes in global levels of histone modifications in a human population in Bangladesh

Yana Chervona, Adriana Arita, Fen Wu, Hong Sun, Kathrine Kiok, Thomas Kluz, Hsiang-Chi Tseng, Jiri Zavadil, Gary Leroy, Mary Gamble, Max Costa
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1996.
https://doi.org/10.1158/1538-7445.AM2011-1996
Published: 15 April 2011
View articletitled, Abstract 1996: Chronic arsenic exposure and changes in global levels of histone modifications in a human population in Bangladesh
Journal Articles

Abstract 2012: Changes in gene expression and global histone marks in a human population exposed to nickel compounds

Adriana G. Arita, Fen Wu, Hong Sun, Kathrin Kiok, Thomas Kluz, Qingshan Qu, Najuan Zhao, Ye Ruan, Jingping Niu, Richard Hayes, Max Costa
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2012.
https://doi.org/10.1158/1538-7445.AM2011-2012
Published: 15 April 2011
View articletitled, Abstract 2012: Changes in gene expression and global histone marks in a human population exposed to nickel compounds
Journal Articles

Abstract 1005: Plk3 functions as an essential component of the survival and hypoxia regulatory pathway by direct phosphorylation and regulation of PTEN and HIF-1α

Yixin Yao, Dazhong Xu, Max Costa, Wei Dai, Luo Lu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1005.
https://doi.org/10.1158/1538-7445.AM2011-1005
Published: 15 April 2011
View articletitled, Abstract 1005: Plk3 functions as an essential component of the survival and hypoxia regulatory pathway by direct phosphorylation and regulation of PTEN and HIF-1α
Journal Articles

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

Xue Zhou, Hong Sun, Haobin Chen, Jiri Zavadil, Thomas Kluz, Adriana Arita, Max Costa
Journal: Cancer Research
Cancer Res (2010) 70 (10): 4214–4221.
https://doi.org/10.1158/0008-5472.CAN-09-2942
Published: 12 May 2010
View articletitled, Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase
Open the PDF for Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase in another window
Includes: Supplementary data
Journal Articles

Abstract 4373: JNK1 participates in the VHL-independent HIF-1α degradation pathway by regulating Hsp90/Hsp70 turnover and the HDAC6-dependent chaperone activity

Dongyun Zhang, Tongjian Cai, Jingxia Li, Max Costa, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4373.
https://doi.org/10.1158/1538-7445.AM10-4373
Published: 15 April 2010
View articletitled, Abstract 4373: JNK1 participates in the VHL-independent HIF-1α degradation pathway by regulating Hsp90/Hsp70 turnover and the HDAC6-dependent chaperone activity
Journal Articles

JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70

Dongyun Zhang, Jingxia Li, Max Costa, Jimin Gao, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2010) 70 (2): 813–823.
https://doi.org/10.1158/0008-5472.CAN-09-0448
Published: 13 January 2010
View articletitled, JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70
Open the PDF for JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70 in another window
Journal Articles

Abstract #5267: Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation

Dongyun Zhang, Weiming Ouyang, Jingxia Li, Udit N. Verma, Max Costa, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5267.
Published: 01 May 2009
View articletitled, Abstract #5267: Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation
Journal Articles

Abstract #492: Inactivation of histone demethylase JMJD1A by carcinogenic nickel compounds

Haobin Chen, Ronghe Zhang, Thomas Kluz, Max Costa
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 492.
Published: 01 May 2009
View articletitled, Abstract #492: Inactivation of histone demethylase JMJD1A by carcinogenic nickel compounds