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Abstract 228: Depletion of stem-loop binding protein and elevation of polyadenylation of histone 3.1 contribute to malignant cell transformation induced by bisphenol A

Arul Veerappan, Zhou Zhang, Max Costa

Cancer Res (2022) 82 (12_Supplement): 228.

DOI: https://doi.org/10.1158/1538-7445.AM2022-228

Published: 15 June 2022

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Journal Articles

Abstract 5993: Inhibition of isorhapontigenin on migration and invasion of bladder cancer cells depends on Sestrin 2 and Beclin 1

Zhuo Zhang, Jingxia Li, Huailu Tu, Max Costa

Cancer Res (2022) 82 (12_Supplement): 5993.

DOI: https://doi.org/10.1158/1538-7445.AM2022-5993

Published: 15 June 2022

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Journal Articles

Abstract 4403: Regulation of SATB2 via miR-31 in Ni-induced malignant cell transformation

Qiao Yi Chen, Yusha Zhu, Ashley Jordan, Jinquan Li, Hong Sun, Thomas Kluz, Max Costa

Cancer Res (2019) 79 (13_Supplement): 4403.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4403

Published: 01 July 2019

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Journal Articles

Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway

Yusha Zhu, Anthony Murphy, Thomas Kluz, Bo Li, Max Costa, Chuanshu Huang, Hong Sun

Cancer Res (2018) 78 (13_Supplement): 5857.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5857

Published: 01 July 2018

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Journal Articles

Abstract 356: Polyadenyaltion of canonical histone mRNA: A potential mechanism of arsenic-induced carcinogenesis

Qiao Yi Chen, Danqi Chen, Thomas Kluz, Feng Wu, Yusha Zhu, Thomas Des Marais, Jinquan Li, Xiaoru Zhang, Ashley Jordan, Hong Sun, Chunyuan Jin, Max Costa

Cancer Res (2018) 78 (13_Supplement): 356.

DOI: https://doi.org/10.1158/1538-7445.AM2018-356

Published: 01 July 2018

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Journal Articles

Abstract 1480: Overexpression of histone H3.1 induced cell malignant transformation and mutation of H3.1 C96/110A further induced chromatin instability

Yusha Zhu, Hong Sun, Max Costa

Cancer Res (2018) 78 (13_Supplement): 1480.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1480

Published: 01 July 2018

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Journal Articles

Abstract 4537: Hexavalent chromium induces H4K16 hypoacetylation by NUPR1-mediated inactivation of histone acetyltransferase hMOF

Qiao Yi Chen, Xiaoru Zhang, Thomas Kluz, Max Costa, Hong Sun

Cancer Res (2016) 76 (14_Supplement): 4537.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4537

Published: 15 July 2016

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Journal Articles

Abstract 3590: Depleted uranium-induced leukemia: Epigenetic and genetic changes.

Alexandra C. Miller, Hailey Clancy, Thomas Kluz, Stuart Cohen, Rafael Rivas, Karvelisse Miller, Max Costa

Cancer Res (2013) 73 (8_Supplement): 3590.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3590

Published: 15 April 2013

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Journal Articles

Abstract 1005: Plk3 functions as an essential component of the survival and hypoxia regulatory pathway by direct phosphorylation and regulation of PTEN and HIF-1α

Yixin Yao, Dazhong Xu, Max Costa, Wei Dai, Luo Lu

Cancer Res (2011) 71 (8_Supplement): 1005.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1005

Published: 15 April 2011

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Journal Articles

Abstract 1996: Chronic arsenic exposure and changes in global levels of histone modifications in a human population in Bangladesh

Yana Chervona, Adriana Arita, Fen Wu, Hong Sun, Kathrine Kiok, Thomas Kluz, Hsiang-Chi Tseng, Jiri Zavadil, Gary Leroy, Mary Gamble, Max Costa

Cancer Res (2011) 71 (8_Supplement): 1996.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1996

Published: 15 April 2011

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Journal Articles

Abstract 2012: Changes in gene expression and global histone marks in a human population exposed to nickel compounds

Adriana G. Arita, Fen Wu, Hong Sun, Kathrin Kiok, Thomas Kluz, Qingshan Qu, Najuan Zhao, Ye Ruan, Jingping Niu, Richard Hayes, Max Costa

Cancer Res (2011) 71 (8_Supplement): 2012.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2012

Published: 15 April 2011

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Journal Articles

Abstract 72: Gene-specific H3K4 trimethylation changes in healthy human subjects exposed to carcinogenic metal components of air particles

Laura Cantone, Thomas Kluz, Letizia Tarantini, Matteo Bonzini, Barbara Marinelli, Pier Alberto Bertazzi, Andrea Baccarelli, Max Costa

Cancer Res (2011) 71 (8_Supplement): 72.

DOI: https://doi.org/10.1158/1538-7445.AM2011-72

Published: 15 April 2011

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Journal Articles

Abstract 5548: Comparison of gene expression profile in chromate transformed BEAS-2B cells

Sun Hong, Harriet A. Clancy, Thomas Kluz, Jiri Zavadil, Max Costa

Cancer Res (2011) 71 (8_Supplement): 5548.

DOI: https://doi.org/10.1158/1538-7445.AM2011-5548

Published: 15 April 2011

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Journal Articles

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

Xue Zhou, Hong Sun, Haobin Chen, Jiri Zavadil, Thomas Kluz, Adriana Arita, Max Costa

Cancer Res (2010) 70 (10): 4214–4221.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-2942

Published: 12 May 2010

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Includes: Supplementary data

Journal Articles

Abstract 4373: JNK1 participates in the VHL-independent HIF-1α degradation pathway by regulating Hsp90/Hsp70 turnover and the HDAC6-dependent chaperone activity

Dongyun Zhang, Tongjian Cai, Jingxia Li, Max Costa, Chuanshu Huang

Cancer Res (2010) 70 (8_Supplement): 4373.

DOI: https://doi.org/10.1158/1538-7445.AM10-4373

Published: 15 April 2010

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Journal Articles

JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70

Dongyun Zhang, Jingxia Li, Max Costa, Jimin Gao, Chuanshu Huang

Cancer Res (2010) 70 (2): 813–823.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-0448

Published: 13 January 2010

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Journal Articles

Abstract #5267: Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation

Dongyun Zhang, Weiming Ouyang, Jingxia Li, Udit N. Verma, Max Costa, Chuanshu Huang

Cancer Res (2009) 69 (9_Supplement): 5267.

Published: 01 May 2009

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Journal Articles

Abstract #492: Inactivation of histone demethylase JMJD1A by carcinogenic nickel compounds

Haobin Chen, Ronghe Zhang, Thomas Kluz, Max Costa

Cancer Res (2009) 69 (9_Supplement): 492.

Published: 01 May 2009

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Journal Articles

Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1α under Hypoxic Conditions

Yali Yang, Jingxiang Bai, Rulong Shen, Sharron A.N. Brown, Elena Komissarova, Ying Huang, Ning Jiang, Gregory F. Alberts, Max Costa, Luo Lu, Jeffrey A. Winkles, Wei Dai

Cancer Res (2008) 68 (11): 4077–4085.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-6182

Published: 02 June 2008

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Includes: Supplementary data

Journal Articles

JNK1, but not JNK2, is required for COX-2 induction by nickel compounds

Dongyun Zhang, Jingxia Li, Kangjian Wu, Weiming Ouyang, Jin Ding, Max Costa, Zheng-gang Liu, Chuanshu Huang

Cancer Res (2008) 68 (9_Supplement): 2230.

Published: 01 May 2008

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NARROW

Abstract 228: Depletion of stem-loop binding protein and elevation of polyadenylation of histone 3.1 contribute to malignant cell transformation induced by bisphenol A

Abstract 5993: Inhibition of isorhapontigenin on migration and invasion of bladder cancer cells depends on Sestrin 2 and Beclin 1

Abstract 4403: Regulation of SATB2 via miR-31 in Ni-induced malignant cell transformation

Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway

Abstract 356: Polyadenyaltion of canonical histone mRNA: A potential mechanism of arsenic-induced carcinogenesis

Abstract 1480: Overexpression of histone H3.1 induced cell malignant transformation and mutation of H3.1 C96/110A further induced chromatin instability

Abstract 4537: Hexavalent chromium induces H4K16 hypoacetylation by NUPR1-mediated inactivation of histone acetyltransferase hMOF

Abstract 3590: Depleted uranium-induced leukemia: Epigenetic and genetic changes.

Abstract 1005: Plk3 functions as an essential component of the survival and hypoxia regulatory pathway by direct phosphorylation and regulation of PTEN and HIF-1α

Abstract 1996: Chronic arsenic exposure and changes in global levels of histone modifications in a human population in Bangladesh

Abstract 2012: Changes in gene expression and global histone marks in a human population exposed to nickel compounds

Abstract 72: Gene-specific H3K4 trimethylation changes in healthy human subjects exposed to carcinogenic metal components of air particles

Abstract 5548: Comparison of gene expression profile in chromate transformed BEAS-2B cells

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

Abstract 4373: JNK1 participates in the VHL-independent HIF-1α degradation pathway by regulating Hsp90/Hsp70 turnover and the HDAC6-dependent chaperone activity

JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70

Abstract #5267: Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation

Abstract #492: Inactivation of histone demethylase JMJD1A by carcinogenic nickel compounds

Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1α under Hypoxic Conditions

JNK1, but not JNK2, is required for COX-2 induction by nickel compounds

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