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Matthias Schwab
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Journal Articles

Abstract 7155: A PD-L1-independent phenotype uncovers responders to combined therapy with immune checkpoint inhibitors in kidney cancer

Free
Florian A. Büttner, Viktor Grünwald, Elfriede Noessner, Igor Tsaur, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7155.
https://doi.org/10.1158/1538-7445.AM2025-7155
Published: 21 April 2025
View articletitled, Abstract 7155: A PD-L1-independent phenotype uncovers responders to combined therapy with immune checkpoint inhibitors in kidney cancer
Journal Articles

Abstract 6845: Evaluation of individual drug response to tyrosine kinase inhibitor treatment in precision-cut tumor slices of gastrointestinal stroma tumors

Free
Dina Mönch, Julia Thiel, Meng Dong, Annika Maaß, Annette M. Staiger, Katrin Kurz, German Ott, Philipp Renner, Tobias Leibold, Thomas Mürdter, Matthias Schwab, Marc-Hendrik Dahlke, Jana Koch
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6845.
https://doi.org/10.1158/1538-7445.AM2025-6845
Published: 21 April 2025
View articletitled, Abstract 6845: Evaluation of individual drug response to tyrosine kinase inhibitor treatment in precision-cut tumor slices of gastrointestinal stroma tumors
Journal Articles

Abstract 728: Identification of high-risk luminal early breast cancer patients based on a p53 signature

Free
Florian A. Büttner, Stefan Winter, Johanna Dahlen, Thomas E. Mürdter, Reiner Hoppe, Peter Fritz, Patrick Danaher, Stephen F. Madden, Matthias Schwab, Werner Schroth
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 728.
https://doi.org/10.1158/1538-7445.AM2025-728
Published: 21 April 2025
View articletitled, Abstract 728: Identification of high-risk luminal early breast cancer patients based on a p53 signature
Journal Articles

Abstract 1602: Advancing personalized medicine using precision-cut tumor slices - assessing individual responses to immunotherapy in the tumor microenvironment

Free
Julia Thiel, Jan Schlegel, Adrian Kneer, Sascha Dreher, Annelie Schäfer, Oliver Seifert, Katrin S. Kurz, Marc-H Dahlke, Georg Sauer, Gerhard Preissler, Laureano Simon, Myriam Fabre, Isabel Egaña, Roland Kontermann, Monilola Olayioye, German Ott, Walter E. Aulitzky, Thomas E. Mürdter, Matthias Schwab, Meng Dong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1602.
https://doi.org/10.1158/1538-7445.AM2025-1602
Published: 21 April 2025
View articletitled, Abstract 1602: Advancing personalized medicine using precision-cut tumor slices - assessing individual responses to immunotherapy in the tumor microenvironment
Journal Articles

Abstract 4478: Development and characterization of kinase sparing TPX2-tethering Aurora kinase A ligands for cancer therapy

Free
Athina Anastasia Moschopoulou, Melanie Henning, Benedikt Wagner, Dirk Flötgen, Juliander Reiner, Yulia Skliarenko, Stefan Zwirner, Clemens Hinterleitner, Marco Seehawer, Luana dArtista, Elke Rist, Tatu Pantsar, Thales Kronenberger, Daniel Dauch, Corinna Gehring-Khav, Antti Poso, Liudmila Andreeva, Matthias Schwab, Michael Forster, Wolfgang Albrecht, Stefan Laufer, Lars Zender
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4478.
https://doi.org/10.1158/1538-7445.AM2024-4478
Published: 22 March 2024
View articletitled, Abstract 4478: Development and characterization of kinase sparing TPX2-tethering Aurora kinase A ligands for cancer therapy
Journal Articles

Abstract 639: Evaluation of individual drug response in tumor microenvironment to cisplatin treatment in precision-cut tumor slices of ovarian cancer

Free
Julia Thiel, Adrian Kneer, Weimeng Yu, Bernd Winkler, Georg Sauer, German Ott, Walter E. Aulitzky, Thomas E. Mürdter, Matthias Schwab, Chunguang Liang, Meng Dong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 639.
https://doi.org/10.1158/1538-7445.AM2024-639
Published: 22 March 2024
View articletitled, Abstract 639: Evaluation of individual drug response in tumor microenvironment to cisplatin treatment in precision-cut tumor slices of ovarian cancer
Journal Articles

Abstract 2020: Nascent proteome analysis of drug response in precision-cut tumor slices

Free
Julia Thiel, Lina-Marie Wagner, Karim Aljakouch, Julia Schüler, Bernd Winkler, Kathrin Böpple, Thomas E. Mürdter, Georg Sauer, German Ott, Walter E. Aulitzky, Matthias Schwab, Jeroen Krijgsveld, Meng Dong
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2020.
https://doi.org/10.1158/1538-7445.AM2023-2020
Published: 04 April 2023
View articletitled, Abstract 2020: Nascent proteome analysis of drug response in precision-cut tumor slices
Journal Articles

Abstract 44: An in vivo platform of pre-characterized renal cell carcinoma (RCC) patient-derived xenograft models allows the preclinical evaluation of patient-tailored intervention strategies

Free
Dennis Kobelt, Dennis Gürgen, Michael Becker, Mathias Dahlmann, Susanne Flechsig, Elke Schaeffeler, Florian A. Büttner, Christian Schmees, Regina Bohnert, Jens Bedke, Matthias Schwab, Johann J. Wendler, Martin Schostak, Burkhard Jandrig, Wolfgang Walther, Jens Hoffmann
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 44.
https://doi.org/10.1158/1538-7445.AM2023-44
Published: 04 April 2023
View articletitled, Abstract 44: An in vivo platform of pre-characterized renal cell carcinoma (RCC) patient-derived xenograft models allows the preclinical evaluation of patient-tailored intervention strategies
Journal Articles

Abstract P2-11-12: The influences of adherence to tamoxifen and CYP2D6 pharmacogenetics on plasma concentrations of the active metabolite (Z)-endoxifen in breast cancer

Free
Jose Claudio Casali da Rocha, Jeanine M Nardin, Werner Schroth, Thais A Almeida, Thomas Mürdter, Solange Picolotto, Evelyn CL Vendramini, Reiner Hoppe, Jenifer P Kogin, Diandra Miqueleto, Silvia DR Moraes, Matthias Schwab, Roberto F Pecoits-Filho, Hiltrud Brauch
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-11-12.
https://doi.org/10.1158/1538-7445.SABCS19-P2-11-12
Published: 15 February 2020
View articletitled, Abstract P2-11-12: The influences of adherence to tamoxifen and CYP2D6 pharmacogenetics on plasma concentrations of the active metabolite (Z)-endoxifen in breast cancer
Journal Articles

Abstract 464: Gene expression signatures for the prediction of endocrine treatment outcome in early-stage luminal breast cancer patients

Free
Werner Schroth, Reiner Hoppe, Florian Büttner, Stefan Winter, Siarhei Kandabarau, Jörg Kumbrink, Heather A. Brauer, Peter Fritz, Matthias Schwab, Thomas Mürdter, Hiltrud Brauch
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 464.
https://doi.org/10.1158/1538-7445.AM2019-464
Published: 01 July 2019
View articletitled, Abstract 464: Gene expression signatures for the prediction of endocrine treatment outcome in early-stage luminal breast cancer patients
Journal Articles

Abstract 2529: Comprehensive genomic analyses of a case series of bilateral renal cell carcinoma

Free
Florian Büttner, Carolin Meyerhoff, Siarhei Kandabarau, Stefan Winter, Steffen Rausch, Arnulf Stenzl, Falko Fend, Christopher Schroeder, Peter Bauer, Per Hoffmann, Markus M. Nöthen, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2529.
https://doi.org/10.1158/1538-7445.AM2019-2529
Published: 01 July 2019
View articletitled, Abstract 2529: Comprehensive genomic analyses of a case series of bilateral renal cell carcinoma
Journal Articles

Abstract 3485: Transcriptomic and metabolomic profiles in renal cell carcinoma (RCC) tumors reflect ontogeny of RCC subtypes

Free
Pascale Fisel, Florian Büttner, Anna Reustle, Verena Klumpp, Stefan Winter, Steffen Rausch, Jörg Hennenlotter, Stephan Kruck, Arnulf Stenzl, Judith Wahrheit, Denise Sonntag, Marcus Scharpf, Falko Fend, Abbas Agaimy, Arndt Hartmann, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3485.
https://doi.org/10.1158/1538-7445.AM2018-3485
Published: 01 July 2018
View articletitled, Abstract 3485: Transcriptomic and metabolomic profiles in renal cell carcinoma (RCC) tumors reflect ontogeny of RCC subtypes
Journal Articles

Abstract 3425: Exome-sequencing derived mutations of endocrine treated ER-positive early breast cancer

Free
Werner Schroth, Siarhei Kandabarau, Peter Fritz, Thomas Mürdter, Liza Bacchus, German Tamoxifen Study Group, Matthias Schwab, Hiltrud Brauch
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3425.
https://doi.org/10.1158/1538-7445.AM2018-3425
Published: 01 July 2018
View articletitled, Abstract 3425: Exome-sequencing derived mutations of endocrine treated ER-positive early breast cancer
Journal Articles

Abstract 5687: Integrative -omics analysis to identify drug targets for ccRCC immunotherapy

Free
Anna Reustle, Moreno Di Marco, Florian Büttner, Stefan Winter, Siarhei Kandabarau, Daniel Kowalewski, Linus Backert, Steffen Rausch, Joerg Hennenlotter, Marcus Scharpf, Falko Fend, Arnulf Stenzl, Jens Bedke, Stefan Stevanovic, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5687.
https://doi.org/10.1158/1538-7445.AM2018-5687
Published: 01 July 2018
View articletitled, Abstract 5687: Integrative -omics analysis to identify drug targets for ccRCC immunotherapy
Journal Articles

Abstract 1843: Intratumoral heterogeneity of renal cancer is related to differences in drug response and development of therapy resistance

Free
Michael Becker, Burkhard Jandrig, Susanne Flechsig, Reiner Zeisig, Daniel Schindele, Martin Schostak, Christian Schmees, Annika Wulf-Goldenberg, Jörg Hennenlotter, Elke Schaeffeler, Matthias Schwab, Arnulf Stenzl, Jens Bedke, Jens Hoffmann
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1843.
https://doi.org/10.1158/1538-7445.AM2017-1843
Published: 01 July 2017
View articletitled, Abstract 1843: Intratumoral heterogeneity of renal cancer is related to differences in drug response and development of therapy resistance
Journal Articles

Abstract 1632: Identification and analysis of EGLN3 as tumor-associated peptide in ccRCC

Free
Anna Reustle, Moreno Di Marco, Florian Büttner, Stefan Winter, Daniel Kowalewski, Linus Backert, Steffen Rausch, Joerg Hennenlotter, Marcus Scharpf, Falko Fend, Arnulf Stenzl, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1632.
https://doi.org/10.1158/1538-7445.AM2017-1632
Published: 01 July 2017
View articletitled, Abstract 1632: Identification and analysis of EGLN3 as tumor-associated peptide in ccRCC
Journal Articles

Abstract 5219: Characterization of the breast cancer resistance protein BCRP in clear cell renal cell carcinoma

Free
Pascale Fisel, Anna Reustle, Olga Renner, Florian Büttner, Stefan Winter, Stephan Kruck, Steffen Rausch, Anne T. Nies, Jörg Hennenlotter, Marcus Scharpf, Falko Fend, Arnulf Stenzl, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5219.
https://doi.org/10.1158/1538-7445.AM2017-5219
Published: 01 July 2017
View articletitled, Abstract 5219: Characterization of the breast cancer resistance protein BCRP in clear cell renal cell carcinoma
Journal Articles

Abstract 5033: Optimized CYP2D6 phenotype assignment for plasma endoxifen prediction in breast cancer patients treated with tamoxifen

Free
Werner Schroth, Stefan Winter, Michel Eichelbaum, Thomas Muerdter, Matthias Schwab, Hiltrud Brauch
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5033.
https://doi.org/10.1158/1538-7445.AM2017-5033
Published: 01 July 2017
View articletitled, Abstract 5033: Optimized CYP2D6 phenotype assignment for plasma endoxifen prediction in breast cancer patients treated with tamoxifen
Journal Articles

OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

Free
Christina D. Drenberg, Alice A. Gibson, Stanley B. Pounds, Lei Shi, Dena P. Rhinehart, Lie Li, Shuiying Hu, Guoqing Du, Anne T. Nies, Matthias Schwab, Navjotsingh Pabla, William Blum, Tanja A. Gruber, Sharyn D. Baker, Alex Sparreboom
Journal: Cancer Research
Cancer Res (2017) 77 (8): 2102–2111.
https://doi.org/10.1158/0008-5472.CAN-16-2548
Published: 13 April 2017
View articletitled, OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Open the PDF for OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues in another window
Includes: Supplementary data
Journal Articles

Abstract 257: Evaluation of organic cation transporter 1 (OCT1, SLC22A1) as transporter for sorafenib

Free
Claudia Neul, Sharyn D. Baker, Alex Sparreboom, Elke Schaeffeler, Stefan Laufer, Matthias Schwab, Anne T. Nies
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 257.
https://doi.org/10.1158/1538-7445.AM2016-257
Published: 15 July 2016
View articletitled, Abstract 257: Evaluation of organic cation transporter 1 (OCT1, SLC22A1) as transporter for sorafenib