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Abstract 1158: Phenotypic screening using AMIDA identifies different drug responses in breast and prostate cancer cell lines in an organotypic cell culture model

Mervi Toriseva, Katja Fagerlund, Jesse Mattsson, Tiina E. Kähkönen, Ilmari Ahonen, Malin Åkerfelt, Jenni Bernoulli, Jussi M. Halleen, Matthias Nees, Jenni H. Mäki-Jouppila

Cancer Res (2018) 78 (13_Supplement): 1158.

https://doi.org/10.1158/1538-7445.AM2018-1158

Published: 01 July 2018

View articletitled, Abstract 1158: Phenotypic screening using AMIDA identifies different drug responses in breast and prostate cancer cell lines in an organotypic cell culture model

Journal Articles

Abstract 2679: Cyanobacterial trypsin-3 inhibitor inhibits prostate cancer cell invasion

Hannu Koistinen, Matti Wahlsten, Muhammad N. Ahmed, Kaarina Sivonen, Matthias Nees, Ulf-Håkan Stenman, David P. Fewer

Cancer Res (2018) 78 (13_Supplement): 2679.

https://doi.org/10.1158/1538-7445.AM2018-2679

Published: 01 July 2018

View articletitled, Abstract 2679: Cyanobacterial trypsin-3 inhibitor inhibits prostate cancer cell invasion

Journal Articles

Abstract 4951: FGFRL1 in prostate cancer progression

Lan Yu, Andrew Erickson, Mervi Toriseva, Teresa Elo, Johanna Tuomela, Heikki Seikkula, Martti Nurmi, Peter Boström, Tuomas Mirtti, Kalle Alanen, Markku Kallajoki, Matthias Nees, Pirkko Härkönen

Cancer Res (2016) 76 (14_Supplement): 4951.

https://doi.org/10.1158/1538-7445.AM2016-4951

Published: 15 July 2016

View articletitled, Abstract 4951: FGFRL1 in prostate cancer progression

Journal Articles

Abstract 1698: Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project

Cancer Res (2015) 75 (15_Supplement): 1698.

https://doi.org/10.1158/1538-7445.AM2015-1698

Published: 01 August 2015

View articletitled, Abstract 1698: Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project

Journal Articles

Abstract 2023: Complex in vitro and in vivo prostate cancer models for the PREDECT consortium

Suzana Vidic, Norbert Esser, Ronald de Hoogt, Ingrid Verberne, Ira Kogan-Sakin, Yan Stein, Varda Rotter, Michael Barbier, Yolanda Chong, Sabine D. Breucker, Karine Smans, Malin Akerfelt, Matthias Nees, Peter King, Ian Hickson, Wytske van Weerden, Ralph Graeser

Cancer Res (2014) 74 (19_Supplement): 2023.

https://doi.org/10.1158/1538-7445.AM2014-2023

Published: 01 October 2014

View articletitled, Abstract 2023: Complex in vitro and in vivo prostate cancer models for the PREDECT consortium

Journal Articles

Abstract A46: Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion

Malin Åkerfelt, Johanna Björk, Tuomas Mirtti, Vidal Fey, Lea Sistonen, Matthias Nees

Cancer Res (2013) 73 (3_Supplement): A46.

https://doi.org/10.1158/1538-7445.TIM2013-A46

Published: 01 May 2014

View articletitled, Abstract A46: Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion

Journal Articles

Abstract 4032: Transcriptomics analyses of normal and transformed keratinocyte lines generated novel biomarkers for prognosticating outcome in head and neck cancer.

Roland C. Grafstrom, Marina Merne, Pekka Kohonen, Fredrik Jerhammar, Matthias Nees, Karin Roberg, Rebecca Ceder

Cancer Res (2013) 73 (8_Supplement): 4032.

https://doi.org/10.1158/1538-7445.AM2013-4032

Published: 15 April 2013

View articletitled, Abstract 4032: Transcriptomics analyses of normal and transformed keratinocyte lines generated novel biomarkers for prognosticating outcome in head and neck cancer.

Journal Articles

Abstract 2597: PLA2G7 associates with aggressive prostate cancer in vivo and regulates prostate cancer cell migration and adhesion in vitro

Paula Vainio, Mika Hilvo, Tiina Vesterinen, Santosh Gupta, Ville Härmä, Matthias Nees, Juha P. Turunen, Johan Lundin, Antti Rannikko, Matej Orešič, Olli Kallioniemi, Kristiina Iljin

Cancer Res (2011) 71 (8_Supplement): 2597.

https://doi.org/10.1158/1538-7445.AM2011-2597

Published: 15 April 2011

View articletitled, Abstract 2597: PLA2G7 associates with aggressive prostate cancer in vivo and regulates prostate cancer cell migration and adhesion in vitro

Journal Articles

FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

Santosh Gupta, Kristiina Iljin, Henri Sara, John Patrick Mpindi, Tuomas Mirtti, Paula Vainio, Juha Rantala, Kalle Alanen, Matthias Nees, Olli Kallioniemi

Cancer Res (2010) 70 (17): 6735–6745.

https://doi.org/10.1158/0008-5472.CAN-10-0244

Published: 31 August 2010

View articletitled, FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

Includes: Supplementary data

Journal Articles

MicroRNAs in bone metastatic breast cancer cells - expression and effects on IL-11 production and cell survival

Sirkku Pollari, Kirsi Hellstrom, Saija Haapa-Paananen, Suvi-Katri Leivonen, Pekka Kohonen, Niko Sahlberg, Merja Perala, Sanna-Maria Kakonen, Matthias Nees, Olli Kallioniemi

Cancer Res (2008) 68 (9_Supplement): 3677.

Published: 01 May 2008

View articletitled, MicroRNAs in bone metastatic breast cancer cells - expression and effects on IL-11 production and cell survival

Journal Articles

High-throughput RNAi and drug screening for the identification and inhibition of oncogenic processes activated by the TMPRSS2-ERG gene fusions in prostate cancer

Kristiina Iljin, Paula Vainio, Mari Bjorkman, Sami Kilpinen, Henri Sara, Maija Wolf, Henrik Edgren, Pekka Kohonen, John Mpindi, Santosh Gupta, Pasi Halonen, Tao He, Merja Perala, Matthias Nees, Olli Kallioniemi

Cancer Res (2008) 68 (9_Supplement): 4129.

Published: 01 May 2008

View articletitled, High-throughput RNAi and drug screening for the identification and inhibition of oncogenic processes activated by the TMPRSS2-ERG gene fusions in prostate cancer

Journal Articles

High-throughput siRNA screening reveals candidate therapeutic targets for clinically aggressive breast cancers, including several genes in the HER-2 amplicon

Kristine Kleivi, Kirsi Hellstrom, Henrik Edgren, Saija Haapa-Paananen, Maija Wolf, Sirkku Pollari, Suvi-Katri Leivonen, Pekka Kohonen, Niko Sahlberg, Rami Makela, Juha Rantala, Pekka Tiikkainen, Petri Saviranta, Anne-Lise Borresen-Dale, Matthias Nees, Merja Perala, Olli Kallioniemi

Cancer Res (2008) 68 (9_Supplement): 918.

Published: 01 May 2008

View articletitled, High-throughput siRNA screening reveals candidate therapeutic targets for clinically aggressive breast cancers, including several genes in the HER-2 amplicon

Journal Articles

Genome-scale uHTP cell microarray siRNA screening: Identification of siRNAs impacting on prostate cancer cell function and maintenance

Juha Rantala, Kristiina Iljin, Paula Ojala, Santosh Gupta, Henrik Edgren, Petri Saviranta, Matthias Nees, Maija Wolf, Olli Kallioniemi

Cancer Res (2008) 68 (9_Supplement): 935.

Published: 01 May 2008

View articletitled, Genome-scale uHTP cell microarray siRNA screening: Identification of siRNAs impacting on prostate cancer cell function and maintenance

Journal Articles

Rapid bioinformatic analysis of gene expression and predicted functions in over 14,000 healthy and cancer tissues: discovery of novel cancer associated kinases

Sami Kilpinen, Reija Autio, Kalle Ojala, Kristiina Iljin, Elmar Bucher, Henri Sara, Tommi Pisto, Rolf Skotheim, Paula Vainio, Kristine Kleivi, Kimmo Jaakkola, Mari Bjorkman, Matti Saarela, Henrik Edgren, Maija Wolf, Jaakko Astola, Sampsa Hautaniemi, Matthias Nees, Olli Kallioniemi

Cancer Res (2008) 68 (9_Supplement): 792.

Published: 01 May 2008

View articletitled, Rapid bioinformatic analysis of gene expression and predicted functions in over 14,000 healthy and cancer tissues: discovery of novel cancer associated kinases

Journal Articles

Histone deacetylase inhibition as a potential therapeutic in ERG-positive prostate cancer

Mari Peltola, Kristiina Iljin, Maija Wolf, Henrik Edgren, Santosh Gupta, Sami Kilpinen, Matthias Nees, Olli Kallioniemi

Cancer Res (2007) 67 (9_Supplement): 685.

Published: 01 May 2007

View articletitled, Histone deacetylase inhibition as a potential therapeutic in ERG-positive prostate cancer

Journal Articles

High-throughput gene silencing in breast cancer by RNAi reveals functional taxonomies and identifies candidate drug targets overexpressed in highly proliferative clinical breast cancers

Kristine Kleivi, Saija Haapa-Paananen, Henrik Edgren, Maija Wolf, Sirkku Pollari, Niko Salhberg, Antti Kulta, Pekka Kohonen, Rami Makela, Juha Rantala, Pekka Tiikkainen, Kirsi Hellstrom, Anne-Lise Borresen-Dale, Petri Saviranta, Matthias Nees, merja Perala, Olli Kallioniemi

Cancer Res (2007) 67 (9_Supplement): 4955.

Published: 01 May 2007

View articletitled, High-throughput gene silencing in breast cancer by RNAi reveals functional taxonomies and identifies candidate drug targets overexpressed in highly proliferative clinical breast cancers

Journal Articles

TMPRSS2 Fusions with Oncogenic ETS Factors in Prostate Cancer Involve Unbalanced Genomic Rearrangements and Are Associated with HDAC1 and Epigenetic Reprogramming

Kristiina Iljin, Maija Wolf, Henrik Edgren, Santosh Gupta, Sami Kilpinen, Rolf I. Skotheim, Mari Peltola, Frank Smit, Gerald Verhaegh, Jack Schalken, Matthias Nees, Olli Kallioniemi

Cancer Res (2006) 66 (21): 10242–10246.

https://doi.org/10.1158/0008-5472.CAN-06-1986

Published: 01 November 2006

View articletitled, TMPRSS2 Fusions with Oncogenic ETS Factors in Prostate Cancer Involve Unbalanced Genomic Rearrangements and Are Associated with HDAC1 and Epigenetic Reprogramming

Includes: Supplementary data

Journal Articles

Human Papillomavirus Type 16 E6 and E7 Proteins Inhibit Differentiation-dependent Expression of Transforming Growth Factor-β2 in Cervical Keratinocytes

Matthias Nees, Joel M. Geoghegan, Peter Munson, Vinayakumar Prabhu, Yun Liu, Elliot Androphy, Craig D. Woodworth

Cancer Res (2000) 60 (15): 4289–4298.

Published: 01 August 2000

View articletitled, Human Papillomavirus Type 16 E6 and E7 Proteins Inhibit Differentiation-dependent Expression of Transforming Growth Factor-β2 in Cervical Keratinocytes

Journal Articles

Targeted Disruption of the Epidermal Growth Factor Receptor Inhibits Development of Papillomas and Carcinomas from Human Papillomavirus-immortalized Keratinocytes

Craig D. Woodworth, Darci Gaiotti, Evan Michael, Laura Hansen, Matthias Nees

Cancer Res (2000) 60 (16): 4397–4402.

Published: 01 August 2000

View articletitled, Targeted Disruption of the Epidermal Growth Factor Receptor Inhibits Development of Papillomas and Carcinomas from Human Papillomavirus-immortalized Keratinocytes

Journal Articles

Expression of Mutated p53 Occurs in Tumor-distant Epithelia of Head and Neck Cancer Patients: A Possible Molecular Basis for the Development of Multiple Tumors

Matthias Nees, Nils Homann, Hilde Discher, Thomas Andl, Christel Enders, Christel Herold-Mende, Antje Schuhmann, Franz X. Bosch

Cancer Res (1993) 53 (18): 4189–4196.

Published: 01 September 1993

View articletitled, Expression of Mutated p53 Occurs in Tumor-distant Epithelia of Head and Neck Cancer Patients: A Possible Molecular Basis for the Development of Multiple Tumors

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Abstract 1158: Phenotypic screening using AMIDA identifies different drug responses in breast and prostate cancer cell lines in an organotypic cell culture model

Abstract 2679: Cyanobacterial trypsin-3 inhibitor inhibits prostate cancer cell invasion

Abstract 4951: FGFRL1 in prostate cancer progression

Abstract 1698: Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project

Abstract 2023: Complex in vitro and in vivo prostate cancer models for the PREDECT consortium

Abstract A46: Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion

Abstract 4032: Transcriptomics analyses of normal and transformed keratinocyte lines generated novel biomarkers for prognosticating outcome in head and neck cancer.

Abstract 2597: PLA2G7 associates with aggressive prostate cancer in vivo and regulates prostate cancer cell migration and adhesion in vitro

FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

MicroRNAs in bone metastatic breast cancer cells - expression and effects on IL-11 production and cell survival

High-throughput RNAi and drug screening for the identification and inhibition of oncogenic processes activated by the TMPRSS2-ERG gene fusions in prostate cancer

High-throughput siRNA screening reveals candidate therapeutic targets for clinically aggressive breast cancers, including several genes in the HER-2 amplicon

Genome-scale uHTP cell microarray siRNA screening: Identification of siRNAs impacting on prostate cancer cell function and maintenance

Rapid bioinformatic analysis of gene expression and predicted functions in over 14,000 healthy and cancer tissues: discovery of novel cancer associated kinases

Histone deacetylase inhibition as a potential therapeutic in ERG-positive prostate cancer

High-throughput gene silencing in breast cancer by RNAi reveals functional taxonomies and identifies candidate drug targets overexpressed in highly proliferative clinical breast cancers

TMPRSS2 Fusions with Oncogenic ETS Factors in Prostate Cancer Involve Unbalanced Genomic Rearrangements and Are Associated with HDAC1 and Epigenetic Reprogramming

Human Papillomavirus Type 16 E6 and E7 Proteins Inhibit Differentiation-dependent Expression of Transforming Growth Factor-β2 in Cervical Keratinocytes

Targeted Disruption of the Epidermal Growth Factor Receptor Inhibits Development of Papillomas and Carcinomas from Human Papillomavirus-immortalized Keratinocytes

Expression of Mutated p53 Occurs in Tumor-distant Epithelia of Head and Neck Cancer Patients: A Possible Molecular Basis for the Development of Multiple Tumors

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