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Matthias M. Gaida
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Journal Articles

Abstract LB317: Liquid-liquid phase separation drives tumorigenesis by modulating the chromatin accessibility of paused and non-paused genes in hepatocellular carcinoma

Free
Alavaro Lucci, Anna E. Barry, Victoria Johnson, Brittany Ruiz, Laura Reynolds, Adam Wojnar, Kasonde Chewe, Yotsawat Pomyen, Christoph Eckert, Kai Zhang, Jason Hill, Ashesh Shah, Adam Bodzin, Elda Grabocka, Matthias M. Gaida, Nicolas Fawzi, Hien Dang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): LB317.
https://doi.org/10.1158/1538-7445.AM2025-LB317
Published: 25 April 2025
View articletitled, Abstract LB317: Liquid-liquid phase separation drives tumorigenesis by modulating the chromatin accessibility of paused and non-paused genes in hepatocellular carcinoma
Journal Articles

Evolutionary Pressures Shape Undifferentiated Pleomorphic Sarcoma Development and Radiotherapy Response

Available to Purchase
Erik S. Blomain, Shaghayegh Soudi, Ziwei Wang, Anish Somani, Ajay Subramanian, Serey C.L. Nouth, Eniola Oladipo, Christin New, Deborah E. Kenney, Neda Nemat-Gorgani, Thomas Kindler, Raffi S. Avedian, Robert J. Steffner, David G. Mohler, Susan M. Hiniker, Alexander L. Chin, Anusha Kalbasi, Michael S. Binkley, Marius Fried, Matthias M. Gaida, Matt van de Rijn, Everett J. Moding
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1162–1174.
https://doi.org/10.1158/0008-5472.CAN-24-3281
Published: 14 March 2025
View articletitled, Evolutionary Pressures Shape Undifferentiated Pleomorphic Sarcoma Development and Radiotherapy Response
Open the PDF for Evolutionary Pressures Shape Undifferentiated Pleomorphic Sarcoma Development and Radiotherapy Response in another window
Includes: Supplementary data
Journal Articles

Abstract 6225: SERPINB3 promotes the aggressive basal-like/squamous subtype and correlates with poor prognosis in pancreatic ductal adenocarcinoma through metabolic reprogramming

Free
Yuuki Ohara, Wei Tang, Liu Huaitian, Shouhui Yang, Peijun He, Helen Cawley, Paloma Valenzuela, Lin Zhang, Jochen Gaedcke, B. Michael Ghadimi, Matthias M. Gaida, Frank Bergmann, H. Richard Alexander, Nader Hanna, Stefan Ambs, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6225.
https://doi.org/10.1158/1538-7445.AM2023-6225
Published: 04 April 2023
View articletitled, Abstract 6225: SERPINB3 promotes the aggressive basal-like/squamous subtype and correlates with poor prognosis in pancreatic ductal adenocarcinoma through metabolic reprogramming
Journal Articles

Abstract 2860: NOSTRIN-induced inhibition of pancreatic cancer progression involves CCBE1 in an eNOS-independent manner

Free
Lin Zhang, Shouhui Yang, Limin Wang, Peijun He, Ohara Yuuki, Paloma Valenzuela, Wei Tang, Jochen Gaedcke, B. Michael Ghadim, Matthias M. Gaida, Frank Bergmann, H. Richard Alexander, Nader Hanna, Brid M Ryan, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2860.
https://doi.org/10.1158/1538-7445.AM2021-2860
Published: 01 July 2021
View articletitled, Abstract 2860: NOSTRIN-induced inhibition of pancreatic cancer progression involves CCBE1 in an eNOS-independent manner
Journal Articles

Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

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Wenjie Huang, Bernat Navarro-Serer, Yea Ji Jeong, Peter Chianchiano, Limin Xia, Claudio Luchini, Nicola Veronese, Cameron Dowiak, Tammy Ng, Maria A. Trujillo, Bo Huang, Michael J. Pflüger, Anne M. Macgregor-Das, Gemma Lionheart, Danielle Jones, Kohei Fujikura, Kim-Vy Nguyen-Ngoc, Neil M. Neumann, Vincent P. Groot, Alina Hasanain, A. Floortje van Oosten, Sandra E. Fischer, Steven Gallinger, Aatur D. Singhi, Amer H. Zureikat, Randall E. Brand, Matthias M. Gaida, Stefan Heinrich, Richard A. Burkhart, Jin He, Christopher L. Wolfgang, Michael G. Goggins, Elizabeth D. Thompson, Nicholas J. Roberts, Andrew J. Ewald, Laura D. Wood
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2804–2817.
https://doi.org/10.1158/0008-5472.CAN-19-1523
Published: 02 July 2020
View articletitled, Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome
Open the PDF for Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract C61: Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer

Free
Shouhui Yang, Wei Tang, Peijun He, Limin Wang, Jochen Gaedcke, B. Michael Ghadim, Philipp Ströbel, Azadeh Azizian, Matthias M. Gaida, Frank Bergmann, H. Richard Alexander, Nader Hanna, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C61.
https://doi.org/10.1158/1538-7445.PANCA19-C61
Published: 13 December 2019
View articletitled, Abstract C61: Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer
Journal Articles

Abstract 4789: A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Free
Shouhui Yang, Peijun He, Liming Wang, Jian Wang, Aaron Schetter, Wei Tang, Naotake Funamizu, Katsuhiko Yanaga, Tadashi Uwagawa, Abhay R. Satoskar, Jochen Gaedcke, Markus Bernhardt, B. Michael Ghadimi, Matthias M Gaida, Frank Bergmann, Jens Werner, Thomas Ried, Nader Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4789.
https://doi.org/10.1158/1538-7445.AM2017-4789
Published: 01 July 2017
View articletitled, Abstract 4789: A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2
Journal Articles

Abstract B34: A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Cancer

Free
Shouhui Yang, Peijun He, Jian Wang, Aaron Schetter, Wei Tang, Naotake Funamizu, Katsuhiko Yanaga, Tadashi Uwagawa, Abhay R. Satoskar, Jochen Gaedcke, Markus Bernhardt, B. Michael Ghadimi, Matthias M. Gaida, Frank Bergmann, Jens Werner, Thomas Ried, Nader Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B34.
https://doi.org/10.1158/1538-7445.PANCA16-B34
Published: 14 December 2016
View articletitled, Abstract B34: A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Cancer
Journal Articles

Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression

Free
Sandeep K. Botla, Soniya Savant, Pouria Jandaghi, Andrea S. Bauer, Oliver Mücke, Evgeny A. Moskalev, John P. Neoptolemos, Eithne Costello, William Greenhalf, Aldo Scarpa, Matthias M. Gaida, Markus W. Büchler, Oliver Strobel, Thilo Hackert, Nathalia A. Giese, Hellmut G. Augustin, Jörg D. Hoheisel
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (14): 4149–4159.
https://doi.org/10.1158/0008-5472.CAN-15-0390
Published: 14 July 2016
View articletitled, Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression
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Includes: Supplementary data
Journal Articles

A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2

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Shouhui Yang, Peijun He, Jian Wang, Aaron Schetter, Wei Tang, Naotake Funamizu, Katsuhiko Yanaga, Tadashi Uwagawa, Abhay R. Satoskar, Jochen Gaedcke, Markus Bernhardt, B. Michael Ghadimi, Matthias M. Gaida, Frank Bergmann, Jens Werner, Thomas Ried, Nader Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3838–3850.
https://doi.org/10.1158/0008-5472.CAN-15-2841
Published: 30 June 2016
View articletitled, A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2
Open the PDF for A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2 in another window
Includes: Supplementary data
Journal Articles

Abstract 923: Nitric oxide signaling pathway as a pathogenic driver in pancreatic cancer

Free
Jian Wang, Peijun He, Matthias M. Gaida, Shouhui Yang, Aaron Schetter, Jochen Gaedcke, Michael Ghadimi, Thomas Ried, Harris G. Yfantis, Dong H. Lee, Jonathan M. Weiss, Nadar Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 923.
https://doi.org/10.1158/1538-7445.AM2015-923
Published: 01 August 2015
View articletitled, Abstract 923: Nitric oxide signaling pathway as a pathogenic driver in pancreatic cancer
Journal Articles

Abstract 4363: Macrophage migration inhibitory factor (MIF) and miR-301b interactively enhance disease aggressiveness by targeting NR3C2 in human pancreatic cancer

Free
Shouhui Yang, Peijun He, Jian Wang, Aaron Schetter, Naotake Funamizu, Katsuhiko Yanaga, Jochen Gaedcke, B. Michael Ghadimi, Matthias M. Gaida, Thomas Ried, Nader Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4363.
https://doi.org/10.1158/1538-7445.AM2014-4363
Published: 01 October 2014
View articletitled, Abstract 4363: Macrophage migration inhibitory factor (MIF) and miR-301b interactively enhance disease aggressiveness by targeting NR3C2 in human pancreatic cancer
Journal Articles

Abstract 926: Nitric oxide enhances tumor progression and disease aggressiveness in pancreatic cancer

Free
Jian Wang, Peijun He, Matthias M. Gaida, Shouhui Yang, Aaron Schetter, Jochen Gaedcke, Michael Ghadimi, Thomas Ried, Harris G. Yfantis, Dong H. Lee, Jonathan M. Weiss, Jim Stauffer, Nader Hanna, H. Richard Alexander, S. Perwez Hussain
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 926.
https://doi.org/10.1158/1538-7445.AM2014-926
Published: 01 October 2014
View articletitled, Abstract 926: Nitric oxide enhances tumor progression and disease aggressiveness in pancreatic cancer