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Matthias Fischer
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Journal Articles

Abstract 2850: Noncoding regulatory mutations as driving event for the oncogenic core regulatory circuitries of neuroblastoma

Mario Capasso, Vincenzo Aievola, Vito Alessandro Lasorsa, Annalaura Montella, Ferdinando Bonfiglio, Marianna Avitabile, Teresa Maiorino, Matilde Tirelli, Giuseppe D'Alterio, Matthias Fischer, Frank Westermann, Achille Iolascon
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2850.
https://doi.org/10.1158/1538-7445.AM2024-2850
Published: 22 March 2024
View article titled, Abstract 2850: Noncoding regulatory mutations as driving event for the oncogenic core regulatory circuitries of neuroblastoma
Journal Articles

Subcellular Distribution of p53 by the p53-Responsive lncRNA NBAT1 Determines Chemotherapeutic Response in Neuroblastoma

Sanhita Mitra, Somsundar Veppil Muralidharan, Mirco Di Marco, Prasanna Kumar Juvvuna, Subazini Thankaswamy Kosalai, Silke Reischl, Daniel Jachimowicz, Santhilal Subhash, Ivan Raimondi, Leo Kurian, Maite Huarte, Per Kogner, Matthias Fischer, John Inge Johnsen, Tanmoy Mondal, Chandrasekhar Kanduri
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1457–1471.
https://doi.org/10.1158/0008-5472.CAN-19-3499
Published: 15 March 2021
View article titled, Subcellular Distribution of p53 by the p53-Responsive lncRNA <em>NBAT1</em> Determines Chemotherapeutic Response in Neuroblastoma
Open the PDF for Subcellular Distribution of p53 by the p53-Responsive lncRNA <em>NBAT1</em> Determines Chemotherapeutic Response in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma

Luca Montemurro, Salvatore Raieli, Silvia Angelucci, Damiano Bartolucci, Camilla Amadesi, Silvia Lampis, Anna Lisa Scardovi, Leonardo Venturelli, Giammario Nieddu, Lucia Cerisoli, Matthias Fischer, Gabriella Teti, Mirella Falconi, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Journal: Cancer Research
Cancer Res (2019) 79 (24): 6166–6177.
https://doi.org/10.1158/0008-5472.CAN-19-0008
Published: 13 December 2019
View article titled, A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma
Open the PDF for A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View article titled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Open the PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface in another window
Includes: Supplementary data
Journal Articles

Abstract LB-051: High LDHA expression predicts decreased survival in neuroblastoma

Carmen Dorneburg, Lisa Christner, Thomas F. Barth, Wolfgang Mueller-Klieser, Matthias Fischer, Hero Barbara, Anneleen Beckers, Frank Speleman, Klaus-Michael Debatin, Christian Beltinger
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-051.
https://doi.org/10.1158/1538-7445.AM2017-LB-051
Published: 01 July 2017
View article titled, Abstract LB-051: High LDHA expression predicts decreased survival in neuroblastoma
Journal Articles

Abstract 1023: Activation of proto-oncogenes by enhancer-hijacking in high‐risk neuroblastoma

Daniel Dreidax, Moritz Gartlgruber, Sebastian Steinhauser, Larisa Savelyeva, Ron Schwessinger, Umut Toprak, Nati Ha, Dilafruz Juraeva, Martin Peifer, Matthias Fischer, Stefan Gröschel, Kai-Oliver Henrich, Young-Gyu Park, Benedikt Brors, Matthias Schlesner, Carl Herrmann, Frank Westermann
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1023.
https://doi.org/10.1158/1538-7445.AM2017-1023
Published: 01 July 2017
View article titled, Abstract 1023: Activation of proto-oncogenes by enhancer-hijacking in high‐risk neuroblastoma
Journal Articles

Abstract 5679: Using droplet digital PCR to analyze MYCN copy number in plasma from patients with high-risk neuroblastoma

Marco Lodrini, Annika Sprüssel, Kathy Astrahantseff, Daniela Tiburtius, Robert Konschak, Holger Lode, Matthias Fischer, Johannes H. Schulte, Angelika Eggert, Hedwig Deubzer
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5679.
https://doi.org/10.1158/1538-7445.AM2017-5679
Published: 01 July 2017
View article titled, Abstract 5679: Using droplet digital PCR to analyze <em>MYCN</em> copy number in plasma from patients with high-risk neuroblastoma
Journal Articles

Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas

Kai-Oliver Henrich, Sebastian Bender, Maral Saadati, Daniel Dreidax, Moritz Gartlgruber, Chunxuan Shao, Carl Herrmann, Manuel Wiesenfarth, Martha Parzonka, Lea Wehrmann, Matthias Fischer, David J. Duffy, Emma Bell, Alica Torkov, Peter Schmezer, Christoph Plass, Thomas Höfer, Axel Benner, Stefan M. Pfister, Frank Westermann
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5523–5537.
https://doi.org/10.1158/0008-5472.CAN-15-2507
Published: 15 September 2016
View article titled, Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Open the PDF for Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas in another window
Includes: Supplementary data
Journal Articles

Abstract 1611: The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting

Michelle Haber, Jayne Murray, Laura Gamble, Ashleigh Carnegie-Clark, Hannah Webber, Michelle Ruhle, Michelle J. Henderson, Shiloh Middlemass, Daniel Carter, Maria Tsoli, Anahid Ehteda, Sandy Simon, Andre Oberthuer, Matthias Fischer, Katerina Gurova, Catherine Burkhart, Andrei Purmal, Richard B. Lock, David Ziegler, Glenn M. Marshall, Andrei V. Gudkov, Murray D. Norris
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1611.
https://doi.org/10.1158/1538-7445.AM2015-1611
Published: 01 August 2015
View article titled, Abstract 1611: The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting
Journal Articles

Abstract LB-210: Telomerase activation by genomic rearrangements in high-risk neuroblastoma

Martin Peifer, Frederik Roels, Falk Hertwig, Roopika Menon, Andrea Kraemer, Reinhard Buettner, Sven Perner, Alexander Schramm, Johannes H. Schulte, Frank Westermann, Roman K. Thomas, Matthias Fischer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-210.
https://doi.org/10.1158/1538-7445.AM2015-LB-210
Published: 01 August 2015
View article titled, Abstract LB-210: Telomerase activation by genomic rearrangements in high-risk neuroblastoma
Journal Articles

GRHL1 Acts as Tumor Suppressor in Neuroblastoma and Is Negatively Regulated by MYCN and HDAC3

Johannes Fabian, Marco Lodrini, Ina Oehme, Marie C. Schier, Theresa M. Thole, Thomas Hielscher, Annette Kopp-Schneider, Lennart Opitz, David Capper, Andreas von Deimling, Inga Wiegand, Till Milde, Ulrich Mahlknecht, Frank Westermann, Odilia Popanda, Frederik Roels, Barbara Hero, Frank Berthold, Matthias Fischer, Andreas E. Kulozik, Olaf Witt, Hedwig E. Deubzer
Journal: Cancer Research
Cancer Res (2014) 74 (9): 2604–2616.
https://doi.org/10.1158/0008-5472.CAN-13-1904
Published: 30 April 2014
View article titled, <em>GRHL1</em> Acts as Tumor Suppressor in Neuroblastoma and Is Negatively Regulated by MYCN and HDAC3
Open the PDF for <em>GRHL1</em> Acts as Tumor Suppressor in Neuroblastoma and Is Negatively Regulated by MYCN and HDAC3 in another window
Includes: Supplementary data
Journal Articles

CAMTA1, a 1p36 Tumor Suppressor Candidate, Inhibits Growth and Activates Differentiation Programs in Neuroblastoma Cells

Kai-Oliver Henrich, Tobias Bauer, Johannes Schulte, Volker Ehemann, Hedwig Deubzer, Sina Gogolin, Daniel Muth, Matthias Fischer, Axel Benner, Rainer König, Manfred Schwab, Frank Westermann
Journal: Cancer Research
Cancer Res (2011) 71 (8): 3142–3151.
https://doi.org/10.1158/0008-5472.CAN-10-3014
Published: 13 April 2011
View article titled, <em>CAMTA1</em>, a 1p36 Tumor Suppressor Candidate, Inhibits Growth and Activates Differentiation Programs in Neuroblastoma Cells
Open the PDF for <em>CAMTA1</em>, a 1p36 Tumor Suppressor Candidate, Inhibits Growth and Activates Differentiation Programs in Neuroblastoma Cells in another window
Includes: Supplementary data
Journal Articles

Transcriptional Repression of SKP2 Is Impaired in MYCN-Amplified Neuroblastoma

Daniel Muth, Seda Ghazaryan, Isabella Eckerle, Emily Beckett, Christina Pöhler, Julia Batzler, Claudia Beisel, Sina Gogolin, Matthias Fischer, Kai-Oliver Henrich, Volker Ehemann, Paul Gillespie, Manfred Schwab, Frank Westermann
Journal: Cancer Research
Cancer Res (2010) 70 (9): 3791–3802.
https://doi.org/10.1158/0008-5472.CAN-09-1245
Published: 28 April 2010
View article titled, Transcriptional Repression of <em>SKP2</em> Is Impaired in <em>MYCN</em>-Amplified Neuroblastoma
Open the PDF for Transcriptional Repression of <em>SKP2</em> Is Impaired in <em>MYCN</em>-Amplified Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 568: Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma

Frank Westermann, Kai-Oliver Henrich, Matthias Fischer, Manfred Schwab
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 568.
https://doi.org/10.1158/1538-7445.AM10-568
Published: 15 April 2010
View article titled, Abstract 568: Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma
Journal Articles

Repository of multi-lab array-based neuroblastoma prognosis data

Xinyu Wen, Qingrong Chen, Jun Wei, Shahab Asgharzdeh, Robert Seeger, Andre Oberthuer, Matthias Fischer, Miki Ohira, Akira Nakagawara, Javed Khan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1733.
Published: 01 May 2008
View article titled, Repository of multi-lab array-based neuroblastoma prognosis data