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Journal Articles

Abstract 1220: Deep mutational scanning of EGFR reveals potential domain-specific TKI sensitivities in lung cancer and glioblastoma

Tikvah Hayes, Elisa Aquilanti, Erica Kim, Nicole Persky, Lisa Brenan, Amy Goodale, Ted Sharpe, Doug Alan, Robert Shue, Lior Golomb, Brianna Silverman, Yvonne Li, Lindsay Westlake, Federica Piccioni, Andrew Cherniack, Xiaoping Yang Yang, David Root, J. Kevin Hicks, Andrew Chi, Jorg Dietrich, Daniel Cahill, Cory Johannessen, Tracy Batchelor, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1220.
https://doi.org/10.1158/1538-7445.AM2024-1220
Published: 22 March 2024
View article titled, Abstract 1220: Deep mutational scanning of EGFR reveals potential domain-specific TKI sensitivities in lung cancer and glioblastoma
Journal Articles

Abstract 4583: An essential role for Cmtr2 in endothelial cell function and vascular development

Alena Yermalovich, Zarin Mohsenin, Bruno Giotti, Douglas Wheeler, Kelly Xu, Alexander Tsankov, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4583.
https://doi.org/10.1158/1538-7445.AM2023-4583
Published: 04 April 2023
View article titled, Abstract 4583: An essential role for Cmtr2 in endothelial cell function and vascular development
Journal Articles

Abstract 5752: Enhancer amplification defines lineage addiction in human lung adenocarcinoma

John Louis Pulice, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5752.
https://doi.org/10.1158/1538-7445.AM2023-5752
Published: 04 April 2023
View article titled, Abstract 5752: Enhancer amplification defines lineage addiction in human lung adenocarcinoma
Journal Articles

Abstract 6130: Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin

Cameron Fraser, Xingping Qin, Kenichi Shimada, Johan Spetz, Mary Heather Florido, Rumani Singh, Stacey Yu, Adam Presser, Zintis Inde, Gaurav Joshi, Jennifer Guerriero, Francisco Sanchez-Rivera, Alison Karst, Omar Lopez, Chendi Li, Peter Winter, Ying Yue, Peter Sorger, Jingwei Cheng, Izidore Lossos, Aaron Hata, Ronny Drapkin, Adam Palmer, James Decaprio, Manisha Thakuria, Charles Yoon, Ursula Matulonis, Matthew Meyerson, Elizabeth Stover, Diana Cardona, Kris Wood, Shayna Sarosiek, David Kirsch, Joseph Mancias, Andrew Cherniack, Anthony Letai, Kristopher Sarosiek
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6130.
https://doi.org/10.1158/1538-7445.AM2023-6130
Published: 04 April 2023
View article titled, Abstract 6130: Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin
Journal Articles

Abstract 433: Mechanisms of resistance to BAY 2927088, the first reversible inhibitor targeting EGFR exon 20 insertion mutations in non-small cell lung cancer

Gizem Karsli Uzunbas, Quinn McVeigh, Akansha Gupta, Stephanie Hoyt, Andrew Cherniack, Franziska Siegel, Stephan Siegel, Matthew Meyerson, Heidi Greulich
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 433.
https://doi.org/10.1158/1538-7445.AM2023-433
Published: 04 April 2023
View article titled, Abstract 433: Mechanisms of resistance to BAY 2927088, the first reversible inhibitor targeting EGFR exon 20 insertion mutations in non-small cell lung cancer
Journal Articles

Abstract 4035: Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer

Franziska Siegel, Gizem Karsli-Uzunbas, Kristyna Kotynkova, Quinn McVeigh, Stephan Siegel, Daniel Korr, Volker Schulze, Markus Berger, Georg Beckmann, Andrew Cherniack, Matthew Meyerson, Heidi Greulich
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4035.
https://doi.org/10.1158/1538-7445.AM2023-4035
Published: 04 April 2023
View article titled, Abstract 4035: Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer
Journal Articles

Abstract P5-14-06: Tumor Genomic Landscape in Older Women with Metastatic Breast Cancer (MBC)

Hersh V. Gupta, Rachel Freedman, Melissa E. Hughes, Yvonne Y. Li, Gregory Kirkner, Janet L. Files, Sarah Strauss, Ana C. Garrido-Castro, Lauren Buckley, Romualdo Barroso-Sousa, Brittany Bychkovsky, Sara Tolaney, Laura MacConaill, Neal Lindeman, Bruce Johnson, Matthew Meyerson, Eric Winer, Deborah A. Dillon, Andrew Cherniack, Nancy U. Lin
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-14-06.
https://doi.org/10.1158/1538-7445.SABCS22-P5-14-06
Published: 01 March 2023
View article titled, Abstract P5-14-06: Tumor Genomic Landscape in Older Women with Metastatic Breast Cancer (MBC)
Journal Articles

Abstract HER2-05: HER2-05 Comprehensive genomic characterization of HER2-low breast cancer

Paolo Tarantino, Hersh V. Gupta, Melissa E. Hughes, Janet L. Files, Sarah Strauss, Gregory Kirkner, Anne-Marie Feeney, Yvonne Y. Li, Ana C. Garrido-Castro, Romualdo Barroso-Sousa, Brittany Bychkovsky, Laura MacConaill, Neal Lindeman, Bruce Johnson, Matthew Meyerson, Sheheryar Kabraji, Rinath Jeselsohn, Xintao Qiu, Rong Li, Henry W. Long, Eric Winer, Deborah A. Dillon, Giuseppe Curigliano, Andrew Cherniack, Sara Tolaney, Nancy U. Lin
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): HER2-05.
https://doi.org/10.1158/1538-7445.SABCS22-HER2-05
Published: 01 March 2023
View article titled, Abstract HER2-05: HER2-05 Comprehensive genomic characterization of HER2-low breast cancer
Journal Articles

Abstract PD7-07: Somatic alterations in primary tumors of patients (pts) with metastatic breast cancer (MBC) may predict likelihood of brain metastasis

Sheheryar Kabraji, Yvonne Y. Li, Melissa E. Hughes, Hersh V. Gupta, Lauren Buckley, Janet L. Files, Ayesha Mohammed-Abreu, Anne-Marie Feeney, Greg Kirkner, Ashka Patel, Ana C. Garrido-Castro, Romualdo Barroso-Sousa, Brittany Bychkovsky, Matthew Meyerson, Sara Tolaney, Deborah A. Dillon, Bruce Johnson, Eric Winer, Andrew Cherniack, Nancy U. Lin
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD7-07.
https://doi.org/10.1158/1538-7445.SABCS22-PD7-07
Published: 01 March 2023
View article titled, Abstract PD7-07: Somatic alterations in primary tumors of patients (pts) with metastatic breast cancer (MBC) may predict likelihood of brain metastasis
Journal Articles

Abstract A003: Enhancer amplification defines lineage addiction in human lung adenocarcinoma

John L. Pulice, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): A003.
https://doi.org/10.1158/1538-7445.CancEpi22-A003
Published: 01 December 2022
View article titled, Abstract A003: Enhancer amplification defines lineage addiction in human lung adenocarcinoma
Journal Articles

Fusobacterium and Colorectal Cancer: Important Association or Random Coincidence?

Blake E. Sanders, Guanxi Qiao, Jodi Hirschman, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2022) 82 (20): 3671–3672.
https://doi.org/10.1158/0008-5472.CAN-22-0099
Published: 17 October 2022
View article titled, <em>Fusobacterium</em> and Colorectal Cancer: Important Association or Random Coincidence?
Open the PDF for <em>Fusobacterium</em> and Colorectal Cancer: Important Association or Random Coincidence? in another window
Journal Articles

Correction: Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines

Zhouwei Zhang, Lior Golomb, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2022) 82 (15): 2808.
https://doi.org/10.1158/0008-5472.CAN-22-2038
Published: 03 August 2022
View article titled, Correction: Functional Genomic Analysis of <em>CDK4</em> and <em>CDK6</em> Gene Dependency across Human Cancer Cell Lines
Open the PDF for Correction: Functional Genomic Analysis of <em>CDK4</em> and <em>CDK6</em> Gene Dependency across Human Cancer Cell Lines in another window
Journal Articles

Abstract SY11-02: Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses

James A. DeCaprio, Jason Nomburg, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): SY11-02.
https://doi.org/10.1158/1538-7445.AM2022-SY11-02
Published: 15 June 2022
View article titled, Abstract SY11-02: Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses
Journal Articles

Abstract ND04: BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy

Stefan Gradl, Sooncheol Lee, Martin Lange, Xiaoyun Wu, Silvia Goldoni, Timothy Lewis, Charlotte Kopitz, Colin Garvie, Philip Lienau, Stephanie Hoyt, Henrik Seidel, Stephan Kaulfuss, Manuel Ellermann, Luc de Waal, Adrian Tersteegen, Sven Golfier, Detlev Suelzle, Christa Hegele-Hartung, James Carr, Frederick Brookfield, Michael Bruening, Melanie Berthold, Thibaud Jourdan, Monica Schenone, Galen Gao, Joseph McGaunn, Antje Wengner, Elisa Aquilanti, Franziska Siegel, Marine Garrido, Annette Walter, Isabelle Genvresse, Andrew Cherniack, Stuart Schreiber, Knut Eis, Ashley Eheim, Matthew Meyerson, Heidi Greulich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): ND04.
https://doi.org/10.1158/1538-7445.AM2022-ND04
Published: 15 June 2022
View article titled, Abstract ND04: BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy
Journal Articles

Abstract 197: A systemic model derivation platform for generating 3D neuroendocrine tumor cell spheroids to accelerate cancer research

Adel Attari, Madison Liistro, Barbara Van Hare, Jennifer Chan, Emma Coleman, Tim Heffernan, Bianca Amador, Matthew Meyerson, Jesse Boehm, William Sellers, Yuen-Yi (Moony) Tseng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 197.
https://doi.org/10.1158/1538-7445.AM2022-197
Published: 15 June 2022
View article titled, Abstract 197: A systemic model derivation platform for generating 3D neuroendocrine tumor cell spheroids to accelerate cancer research
Journal Articles

Abstract 46: Independent clonal origins of synchronous primary tumors in multifocal ileal neuroendocrine tumor patients

NETTA MÄKINEN, Meng Zhou, Zhouwei Zhang, Yosuke Kasai, Elizabeth Perez, Grace E. Kim, Chrissie Thirlwell, Eric Nakakura, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 46.
https://doi.org/10.1158/1538-7445.AM2022-46
Published: 15 June 2022
View article titled, Abstract 46: Independent clonal origins of synchronous primary tumors in multifocal ileal neuroendocrine tumor patients
Journal Articles

Abstract 879: SLFN12-mediated depletion of tRNA-Leu-TAA by velcrin treatment induces ribosome pausing at Leu-TTA codons and represses global translation initiation

Stephanie Hoyt, Sooncheol Lee, Joseph McGaunn, Andrew Cherniack, Matthew Meyerson, Heidi Greulich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 879.
https://doi.org/10.1158/1538-7445.AM2022-879
Published: 15 June 2022
View article titled, Abstract 879: SLFN12-mediated depletion of tRNA-Leu-TAA by velcrin treatment induces ribosome pausing at Leu-TTA codons and represses global translation initiation
Journal Articles

Abstract 867: Velcrin-induced cleavage of tRNA-Leu-TAA by SLFN12 RNase causes cancer cell death

Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin Garvie, Joseph McGaunn, Andrew D. Cherniack, Matthew Meyerson, Heidi Greulich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2022-867
Published: 15 June 2022
View article titled, Abstract 867: Velcrin-induced cleavage of tRNA-Leu-TAA by SLFN12 RNase causes cancer cell death
Journal Articles

Abstract 2151: Identification and proteogenomic characterization of novel lung adenocarcinoma subtypes with therapeutic relevance

Whijae Roh, Yifat Geffen, Mendy Miller, Shankara Anand, Jaegil Kim, David Heiman, Matthew Meyerson, Peter Laird, Andrew Cherniack, NCI CCG Tumor Molecular Pathology (TMP) Analysis Working Group, Gad Getz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2151.
https://doi.org/10.1158/1538-7445.AM2022-2151
Published: 15 June 2022
View article titled, Abstract 2151: Identification and proteogenomic characterization of novel lung adenocarcinoma subtypes with therapeutic relevance
Journal Articles

Abstract 2663: Preclinical profiling of BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy

Silvia Goldoni, Martin Lange, Charlotte Kopitz, Stefan Kaulfuss, Sven Golfier, Adrian Tersteegen, Stefanie Bunse, Melanie Berthold, Thibaud Jordan, Philip Lienau, Franziska Siegel, Annette Walter, Henrik Seidel, Elisa Aquilanti, Andrew Baker, Xiaoyun Wu, Sooncheol Lee, Stefan Gradl, Emmanuelle di Tomaso, Matthew Meyerson, Knut Eis, Ashley Eheim, Heidi Greulich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2663.
https://doi.org/10.1158/1538-7445.AM2022-2663
Published: 15 June 2022
View article titled, Abstract 2663: Preclinical profiling of BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy