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Matthew D. Hall
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Journal Articles

Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

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Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou, Yaqin Zhang, Changmin Peng, Yunxiao Meng, Zhuqing Li, Muhammad Jameel Mughal, Yanjun Gao, Edward Seto, Min Shen, Matthew D. Hall, Junfeng Ma, Cynthia X. Ma, Shunqiang Li, Wenge Zhu
Journal: Cancer Research
Cancer Res (2025) 85 (9): 1708–1724.
https://doi.org/10.1158/0008-5472.CAN-24-2492
Published: 02 May 2025
View articletitled, Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer
Open the PDF for Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2248: Inhibiting NNMT in cancer-associated fibroblasts reduces immunosuppression

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Janna Heide, Agnes J. Bilecz, Maria F. Allega, Samarjit Patnaik, Gordon M. Stott, Matthew D. Hall, Andras Piffko, Ernst Lengyel
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2248.
https://doi.org/10.1158/1538-7445.AM2025-2248
Published: 21 April 2025
View articletitled, Abstract 2248: Inhibiting NNMT in cancer-associated fibroblasts reduces immunosuppression
Journal Articles

Abstract 3169: Dependency-agnostic drug discovery: A dual-screening strategy to uncover novel cancer vulnerabilities

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Olasunkanmi Olaoye, Colleen Harrington, Kenneth N. Ross, Allen T. Basanthakumar, Jamie O. Brett, Shakchhi Joshi, Jonathan H. Shrimp, Min Shen, Lucy Merickel, Audrey Taillon, Silvi Salhotra, Bo Kyung A. Seong, Ji Seul Han, Yara R. Zabala, Ashleigh Meyer, Qi Liu, Luc de Waal, Jun Qi, Matthew D. Hall, Marcia C. Haigis, Jennifer Roth, Kimberly Stegmaier
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3169.
https://doi.org/10.1158/1538-7445.AM2025-3169
Published: 21 April 2025
View articletitled, Abstract 3169: Dependency-agnostic drug discovery: A dual-screening strategy to uncover novel cancer vulnerabilities
Journal Articles

Abstract A004: Lymphopenia and spleen dose for inoperable pancreatic cancer patients receiving ablative 5-fraction radiation therapy

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Michael D. Chuong, Roberto Herrera, Nicolas Carvallo, Muni Rubens, Rupesh Kotecha, Matthew D. Hall, Kathryn E. Mittauer, Nema Bassiri-Gharb, Alonso N. Gutierrez, Adeel Kaiser
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A004.
https://doi.org/10.1158/1538-7445.PANCA2023-A004
Published: 16 January 2024
View articletitled, Abstract A004: Lymphopenia and spleen dose for inoperable pancreatic cancer patients receiving ablative 5-fraction radiation therapy
Journal Articles

Abstract PR08: Lactate dehydrogenase A is a pharmacologically tractable EWS-FLI1 transcriptional target that regulates the glycolytic dependence of Ewing sarcoma

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Choh Yeung, Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Marielle E. Yohe, Haiyan Lei, Ganesha Rai, Daniel J. Urban, Michelle S. Johnson, Gloria A. Benevides, Giuseppe L. Squadrito, Sandy Eldridge, John Hamre, III, Arnulfo Mendoza, Jack F. Shern, Lee J. Helman, Murali C. Krishna, Matthew D. Hall, Victor M. Darley-Usmar, Leonard M. Neckers, Christine M. Heske
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): PR08.
https://doi.org/10.1158/1538-7445.PEDCA19-PR08
Published: 15 July 2020
View articletitled, Abstract PR08: Lactate dehydrogenase A is a pharmacologically tractable EWS-FLI1 transcriptional target that regulates the glycolytic dependence of Ewing sarcoma
Journal Articles

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

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Choh Yeung, Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa, Ganesha Rai, Daniel J. Urban, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Marielle E. Yohe, Haiyan Lei, Sandy Eldridge, John Hamre, III, Tyrone Dowdy, Victor Ruiz-Rodado, Adrian Lita, Arnulfo Mendoza, Jack F. Shern, Mioara Larion, Lee J. Helman, Gordon M. Stott, Murali C. Krishna, Matthew D. Hall, Victor Darley-Usmar, Leonard M. Neckers, Christine M. Heske
Journal: Cancer Research
Cancer Res (2019) 79 (19): 5060–5073.
https://doi.org/10.1158/0008-5472.CAN-19-0217
Published: 01 October 2019
View articletitled, Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma
Open the PDF for Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma in another window
Includes: Supplementary data
Journal Articles

Abstract LB-066: A high-throughput screen of an annotated small molecule library identifies substrates of P-glycoprotein

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Tobie D. Lee, Olivia W. Lee, Kyle R. Brimacombe, Min Shen, Lu Chen, Rajarshi Guha, Bethelihem Tebase, Robert W. Robey, Suresh V. Ambudkar, Michael M. Gottesman, Matthew D. Hall
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-066.
https://doi.org/10.1158/1538-7445.AM2018-LB-066
Published: 01 July 2018
View articletitled, Abstract LB-066: A high-throughput screen of an annotated small molecule library identifies substrates of P-glycoprotein
Journal Articles

Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes

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Matthew D. Hall, Katherine A. Telma, Ki-Eun Chang, Tobie D. Lee, James P. Madigan, John R. Lloyd, Ian S. Goldlust, James D. Hoeschele, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2014) 74 (14): 3913–3922.
https://doi.org/10.1158/0008-5472.CAN-14-0247
Published: 14 July 2014
View articletitled, Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes
Open the PDF for Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes in another window
Includes: Supplementary data
Journal Articles

Abstract 944: The effect of endogenous peroxidase activity on cell culture-based drug activity screening.

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Joshua Bakhsheshian, Alexandra D.T. Kwit, Kyle R. Brimacombe, Matthew D. Hall, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 944.
https://doi.org/10.1158/1538-7445.AM2013-944
Published: 15 April 2013
View articletitled, Abstract 944: The effect of endogenous peroxidase activity on cell culture-based drug activity screening.
Journal Articles

Abstract B12: The miR-15 family and miR-155 mediate WEE1 and CHEK1 effects on cisplatin-resistance in cancer cells

Free
Lynn M. Pouliot, Jennifer Bai, Matthew D. Hall, Scott E. Martin, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2012) 72 (2_Supplement): B12.
https://doi.org/10.1158/1538-7445.NONRNA12-B12
Published: 03 April 2013
View articletitled, Abstract B12: The miR-15 family and miR-155 mediate WEE1 and CHEK1 effects on cisplatin-resistance in cancer cells
Journal Articles

Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family

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Lynn M. Pouliot, Yu-Chi Chen, Jennifer Bai, Rajarshi Guha, Scott E. Martin, Michael M. Gottesman, Matthew D. Hall
Journal: Cancer Research
Cancer Res (2012) 72 (22): 5945–5955.
https://doi.org/10.1158/0008-5472.CAN-12-1400
Published: 14 November 2012
View articletitled, Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family
Open the PDF for Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family in another window
Includes: Supplementary data
Journal Articles

Abstract 843: Influx of thiosemicarbazone NSC73306 is mediated by the cisplatin and copper transporter SLC31A1 (CTR1)

Free
King Leung Fung, Abisola K. Tepede, Kristen M. Pluchino, Matthew D. Hall, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 843.
https://doi.org/10.1158/1538-7445.AM2012-843
Published: 15 April 2012
View articletitled, Abstract 843: Influx of thiosemicarbazone NSC73306 is mediated by the cisplatin and copper transporter SLC31A1 (CTR1)
Journal Articles

Abstract 3533: Resistance is useless: Development of the MDR1-selective agent NSC73306

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Matthew D. Hall, Misty D. Handley, Kristen Pluchino, Kyle R. Brimacombe, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3533.
https://doi.org/10.1158/1538-7445.AM10-3533
Published: 15 April 2010
View articletitled, Abstract 3533: Resistance is useless: Development of the MDR1-selective agent NSC73306
Journal Articles

Identification of Compounds Selectively Killing Multidrug-Resistant Cancer Cells

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Dóra Türk, Matthew D. Hall, Benjamin F. Chu, Joseph A. Ludwig, Henry M. Fales, Michael M. Gottesman, Gergely Szakács
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8293–8301.
https://doi.org/10.1158/0008-5472.CAN-09-2422
Published: 28 October 2009
View articletitled, Identification of Compounds Selectively Killing Multidrug-Resistant Cancer Cells
Open the PDF for Identification of Compounds Selectively Killing Multidrug-Resistant Cancer Cells in another window
Includes: Supplementary data