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Matthew A. Coelho
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Journal Articles

Abstract 420: On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells

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Gabriele Picco, Yanhua Rao, Angham Al Saedi, Samantha J. Walker, Shriram Bhosle, Yang Lee, Sara F. Vieira, Gilberto Valdes Garcia, Kieron May, Francesco Sassi, Mamta Sharma, Cansu Dincer, Inigo Barrio Hernandez, Theo Bell, Anastasia Kavasakali, Maria Garcia-Casado, Ray Shenje, Cuthbert Martyr, Edward Brnardic, Nanhua Deng, Hristina Grigorova Dimitrova, Emre Karakoc, Emma Hitch, Katrina McCarten, Zoe Hewitson, Howard Lightfoot, Syd Barthorpe, Michael P. DeMartino, Phil Landis, Emanuel Gonçalves, Andrea Bertotti, Livio Trusolino, Geeta Sharma, Matthew A. Coelho, Jonathan Houseley, Benjamin Schwartz, Mathew J. Garnett
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 420.
https://doi.org/10.1158/1538-7445.AM2025-420
Published: 21 April 2025
View articletitled, Abstract 420: On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells
Journal Articles

An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations

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Jesse Boumelha, Sophie de Carné Trécesson, Emily K. Law, Pablo Romero-Clavijo, Matthew A. Coelho, Kevin W. Ng, Edurne Mugarza, Christopher Moore, Sareena Rana, Deborah R. Caswell, Miguel Murillo, David C. Hancock, Prokopios P. Argyris, William L. Brown, Cameron Durfee, Lindsay K. Larson, Rachel I. Vogel, Alejandro Suárez-Bonnet, Simon L. Priestnall, Philip East, Sarah J. Ross, George Kassiotis, Miriam Molina-Arcas, Charles Swanton, Reuben Harris, Julian Downward
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3435–3448.
https://doi.org/10.1158/0008-5472.CAN-22-0325
Published: 04 October 2022
View articletitled, An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations
Open the PDF for An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations in another window
Includes: Supplementary data