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Matteo Fassan
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Journal Articles

Abstract 2014: Immune exclusion signatures identify patients at high risk of relapse despite adjuvant chemotherapy in stage 2 colon cancer in the TOSCA phase 3 trial: PROSIT study

Free
Luca Mazzarella, Alberto Puccini, Lorenzo Ferrando, Gianmaria Frige', Eliana Rulli, Anna Maria Pessino, Alessandro Pastorino, Valentino Martelli, Anna Garuti, Davide Bedognetti, Alberto Ballestrero, Valter Torri, Roberto Labianca, Matteo Fassan, Sara Lonardi, Gabriele Zoppoli, Alberto Sobrero
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2014.
https://doi.org/10.1158/1538-7445.AM2025-2014
Published: 21 April 2025
View articletitled, Abstract 2014: Immune exclusion signatures identify patients at high risk of relapse despite adjuvant chemotherapy in stage 2 colon cancer in the TOSCA phase 3 trial: PROSIT study
Journal Articles

Abstract PO1-03-09: Transcriptomic profiling of ER-negative and ER-low, HER2-negative breast cancer and its implications on immune regulation

Free
Gaia Griguolo, Claudio Vernieri, Davide Massa, Lorenzo Nicolè, Claudia Pinato, Federica Miglietta, Andrea Vingiani, Silvia Brich, Riccardo Lobefaro, Francesca Schiavi, Matteo Fassan, Giancarlo Pruneri, Valentina Guarneri, Maria Vittoria Dieci
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-03-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-03-09
Published: 02 May 2024
View articletitled, Abstract PO1-03-09: Transcriptomic profiling of ER-negative and ER-low, HER2-negative breast cancer and its implications on immune regulation
Journal Articles

Abstract PO3-13-06: TILs are an independent prognostic factor in early-stage TNBC patients achieving pathologic complete response after neoadjuvant chemotherapy

Free
Maria Vittoria Dieci, Claudio Vernieri, Davide Massa, Lorenzo Nicolè, Gaia Griguolo, Federica Miglietta, Andrea Vingiani, Riccardo Lobefaro, Fabio Girardi, Grazia Vernaci, Tommaso Giarratano, Carlo Alberto Giorgi, Giancarlo Pruneri, Matteo Fassan, Filippo De Braud, Valentina Guarneri
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-13-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-13-06
Published: 02 May 2024
View articletitled, Abstract PO3-13-06: TILs are an independent prognostic factor in early-stage TNBC patients achieving pathologic complete response after neoadjuvant chemotherapy
Journal Articles

Abstract 1014: High tumor mutational burden in patients with mismatch repair proficient metastatic colorectal cancer: Single institution cohort

Free
Giulia Maddalena, Valentina Angerilli, Gianmarco Ricagno, Aldo Montagna, Riccardo Cerantola, Giada Munari, Sara Lonardi, Francesca Bergamo, Matteo Fassan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1014.
https://doi.org/10.1158/1538-7445.AM2023-1014
Published: 04 April 2023
View articletitled, Abstract 1014: High tumor mutational burden in patients with mismatch repair proficient metastatic colorectal cancer: Single institution cohort
Journal Articles

Abstract PD7-08: Gene Expression Profiling of Breast Cancer Brain Metastasis shows enrichment for non-luminal subtypes with potential prognostic implications

Free
Gaia Griguolo, Maria Vittoria Dieci, Susan Fineberg, claudia Pinato, Michele Bottosso, Luc Bauchet, Federica Miglietta, Jack Jacob, Giovanni Zarrilli, Valérie Rigau, Maria Cristina Guarascio, Francesca Zanconato, Francesca Schiavi, Matteo Fassan, William Jacot, Stefano Piccolo, Amelie Darlix, Valentina Guarneri
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD7-08.
https://doi.org/10.1158/1538-7445.SABCS22-PD7-08
Published: 01 March 2023
View articletitled, Abstract PD7-08: Gene Expression Profiling of Breast Cancer Brain Metastasis shows enrichment for non-luminal subtypes with potential prognostic implications
Journal Articles

Abstract 1269: Negative ultra-selection of patients with RAS/BRAF wild-type (wt), microsatellite stable (MSS) metastatic colorectal cancer (mCRC) receiving anti-EGFR-based therapy: The PRESSING2 study

Free
Giovanni Randon, Giulia Maddalena, Marco Maria Germani, Filippo Pagani, Francesca Bergamo, Mirella Giordano, Chiara Pircher, Caterina Sposetti, Luca Zambelli, Francesca Corti, Marta Bini, Alessandro Rametta, Andrea Spagnoletti, Aldo Montagna, Matteo Fassan, Alessandra Boccaccino, Guglielmo Vetere, Silvia Damian, Massimo Milione, Filippo de Braud, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1269.
https://doi.org/10.1158/1538-7445.AM2022-1269
Published: 15 June 2022
View articletitled, Abstract 1269: Negative ultra-selection of patients with RAS/BRAF wild-type (wt), microsatellite stable (MSS) metastatic colorectal cancer (mCRC) receiving anti-EGFR-based therapy: The PRESSING2 study
Journal Articles

Abstract A045: Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer

Free
Alison May Berner, Calum Gabbutt, Salpie Nowinski, Jacob Househam, Nick Trahearn, George D. Cresswell, Vinaya Srirangam Nadhamuni, Christopher Kimberley, Matteo Fassan, Ann-Marie Baker, Andrea Sottoriva, Christina Thirlwell, John Bridgewater, Trevor Graham
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): A045.
https://doi.org/10.1158/1538-7445.EVODYN22-A045
Published: 15 May 2022
View articletitled, Abstract A045: Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer
Journal Articles

Abstract P2-12-04: Characterization of gut microbiome composition in triple negative breast cancer patients treated with neoadjuvant chemotherapy

Free
Grazia Maria Vernaci, Davide Massa, Ilaria Patuzzi, Alice Menichetti, Tommaso Giarratano, Gaia Griguolo, Federica Miglietta, Matteo Fassan, Edoardo Savarino, PierFranco Conte, Valentina Guarneri, Maria Vittoria Dieci
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-12-04.
https://doi.org/10.1158/1538-7445.SABCS21-P2-12-04
Published: 15 February 2022
View articletitled, Abstract P2-12-04: Characterization of gut microbiome composition in triple negative breast cancer patients treated with neoadjuvant chemotherapy
Journal Articles

Abstract 2373: Expression of exosomal let-7g in biofluids and outcome in colon cancer patient treated with anti-EGFR therapy

Free
Jens C. Hahne, Andrea Lampis, Michele Ghidini, Margherita Ratti, Chiara Senti, Rodolfo Passalacqua, Luciano Cascione, Chiara Braconi, Owen Sansom, Matteo Fassan, Nicola Valeri
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2373.
https://doi.org/10.1158/1538-7445.AM2021-2373
Published: 01 July 2021
View articletitled, Abstract 2373: Expression of exosomal let-7g in biofluids and outcome in colon cancer patient treated with anti-EGFR therapy
Journal Articles

CKAP2L Promotes Non–Small Cell Lung Cancer Progression through Regulation of Transcription Elongation

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Tiziana Monteverde, Sudhakar Sahoo, Manuela La Montagna, Peter Magee, Lei Shi, Dave Lee, Robert Sellers, Alexander R. Baker, Hui Sun Leong, Matteo Fassan, Michela Garofalo
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1719–1731.
https://doi.org/10.1158/0008-5472.CAN-20-1968
Published: 01 April 2021
View articletitled, CKAP2L Promotes Non–Small Cell Lung Cancer Progression through Regulation of Transcription Elongation
Open the PDF for CKAP2L Promotes Non–Small Cell Lung Cancer Progression through Regulation of Transcription Elongation in another window
Includes: Supplementary data
Journal Articles

Abstract 5720: MicroRNA deregulation of the serine synthesis pathway controls intrinsic and non-cell autonomous mechanism of resistance to Regorafenib in metastatic colorectal cancer (mCRC)

Free
Somaieh Hedayat, Andrea Lampis, George Vlachogiannis, khurum Khan, Silvia Marchetti, Matteo Fassan, Michele Ghidini, Ruwaida Begum, Marta Schirripa, Rodolfo Passalacqua, David Cunningham, Fotios Loupakis, Nicola Valeri
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5720.
https://doi.org/10.1158/1538-7445.AM2020-5720
Published: 15 August 2020
View articletitled, Abstract 5720: MicroRNA deregulation of the serine synthesis pathway controls intrinsic and non-cell autonomous mechanism of resistance to Regorafenib in metastatic colorectal cancer (mCRC)
Journal Articles

Abstract CT261: METAMECH -A Master Observational Trial empowering mechanobiology translational research and mechanobased proof of concept trials in breast cancer

Free
Paolo Luraghi, Luca Lazzari, Maria Vittoria Dieci, Serena Bellani, Chiara Soffientini, Rosario Rizzuto, Antonio Rosato, Vincenzo Costanzo, Giorgio Scita, Giannino Del Sal, Massimiliano Pagani, Marco Foiani, Claudio Tripodo, Silvio Bicciato, Giovanni Blandino, Alberto Zambelli, Valter Torri, Matteo Fassan, PierFranco Conte, Silvia Marsoni, Stefano Piccolo
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT261.
https://doi.org/10.1158/1538-7445.AM2020-CT261
Published: 15 August 2020
View articletitled, Abstract CT261: METAMECH -A Master Observational Trial empowering mechanobiology translational research and mechanobased proof of concept trials in breast cancer
Journal Articles

Abstract CT263: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: The PEGASUS trial

Free
Elena Elez, Filippo Pietrantonio, Andrea Sartore-Bianchi, Clara Montagut, Andres Cervantes, Stefania Sciallero, Maria Giulia Zampino, Stefania Mosconi, Valter Torri, Noelia Tarazona, Luca Lazzari, Paolo Luraghi, Susana Muñoz, Matteo Fassan, Enzo Medico, Livio Trusolino, Maria Rescigno, Salvatore Siena, Alberto Sobrero, Roberto Labianca, Josep Tabernero, Alberto Bardelli, Sara Lonardi, Silvia Marsoni
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT263.
https://doi.org/10.1158/1538-7445.AM2020-CT263
Published: 15 August 2020
View articletitled, Abstract CT263: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: The PEGASUS trial
Journal Articles

Abstract 258: MicroRNAs as biomarkers of resistance to HER2 inhibition in combination with chemotherapy in gastro-esophageal cancer

Free
Hazel Lote, Andrea Lampis, George Vlachogiannis, Jens Hahne, Sing-Yu Moorcraft, Michael Davidson, Carolin Fong, Ruwaida Begum, Matteo Fassan, Sheela Rao, David Watkins, Naureen Starling, Ian Chau, David Cunningham, Nicola Valeri
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 258.
https://doi.org/10.1158/1538-7445.AM2020-258
Published: 15 August 2020
View articletitled, Abstract 258: MicroRNAs as biomarkers of resistance to HER2 inhibition in combination with chemotherapy in gastro-esophageal cancer
Journal Articles

Abstract 235: Preclinical activity of an antibody drug conjugate targeting tumor specificmuc1 structural peptide-glycotope

Free
Marc Trombe, Anne Caron, Alexia Tellier, Chantal Carrez, Stephane Guérif, Severine Clavier, Nathalie Karst, Juhani Saarinen, Tero Satomaa, Virve Pitkänen, Olli Aitio, Annamari Heiskanen, Matteo Fassan, Jan Pinkas, Raffaele Baffa, Veronique Blanc, Celine Nicolazzi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 235.
https://doi.org/10.1158/1538-7445.AM2019-235
Published: 01 July 2019
View articletitled, Abstract 235: Preclinical activity of an antibody drug conjugate targeting tumor specificmuc1 structural peptide-glycotope
Journal Articles

Abstract LB-305: Circulating miR-652-3p as a biomarker of resistance to regorafenib in metastatic colorectal cancer patients

Free
Somaieh Hedayat, Khurum Khan, David Cunningham, George Vlachogiannis, Andrea Lampis, Silvia Marchetti, Matteo Fassan, Ruwaida Begum, Marta Schirripa, Fotios Fotios Loupakis, Nicola Valeri
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-305.
https://doi.org/10.1158/1538-7445.AM2019-LB-305
Published: 01 July 2019
View articletitled, Abstract LB-305: Circulating miR-652-3p as a biomarker of resistance to regorafenib in metastatic colorectal cancer patients
Journal Articles

The TLR7/8/9 Antagonist IMO-8503 Inhibits Cancer-Induced Cachexia

Free
Federica Calore, Priya Londhe, Paolo Fadda, Giovanni Nigita, Lucia Casadei, Gioacchino Paolo Marceca, Matteo Fassan, Francesca Lovat, Pierluigi Gasparini, Lara Rizzotto, Nicola Zanesi, Devine Jackson, Svasti Mehta, Patrick Nana-Sinkam, Deepa Sampath, Raphael E. Pollock, Denis C. Guttridge, Carlo M. Croce
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6680–6690.
https://doi.org/10.1158/0008-5472.CAN-17-3878
Published: 03 December 2018
View articletitled, The TLR7/8/9 Antagonist IMO-8503 Inhibits Cancer-Induced Cachexia
Open the PDF for The TLR7/8/9 Antagonist IMO-8503 Inhibits Cancer-Induced Cachexia in another window
Journal Articles

Abstract 4977: MIR1307 mediates pancreatic cancer resistance to FOLFIRINOX chemotherapy by affecting response to DNA damage

Free
Pietro Carotenuto, Domenico Zito, Maria C. Previdi, Maya Raj, Matteo Fassan, Andrea Lampis, Francesco Scalafani, Andrea Lanese, Ian Said-Huntingford, Jens C. Hahne, Kate Young, Ruwaida Begum, Zakaria Ethiar, Andrew Wotherspoon, Naureen Starling, Anguraj Sadanandam, David Cunningham, Ian Chau, Paul Workman, Rajesh Chopra, Nicola Valeri, Chiara Braconi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4977.
https://doi.org/10.1158/1538-7445.AM2018-4977
Published: 01 July 2018
View articletitled, Abstract 4977: MIR1307 mediates pancreatic cancer resistance to FOLFIRINOX chemotherapy by affecting response to DNA damage
Journal Articles

Abstract 1823: Identification of molecular determinants of vinorelbine resistance in BRAF(V600E) mutated chemorefractory metastatic colorectal cancer patients

Free
Loredana Vecchione, Ines Beumer, Antonio Mulero-Sanchez, Mireille Snel, Filippo Pietrantonio, Chiara Cremolini, Fotios Loupakis, Antonia Martinetti, Giovanni Fuca', Roberto Moretto, Gabriella Fontanini, Matteo Fassan, Sara Lonardi, Marta Schirripa, Ulrich Keilholz, Rene' Bernards
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1823.
https://doi.org/10.1158/1538-7445.AM2018-1823
Published: 01 July 2018
View articletitled, Abstract 1823: Identification of molecular determinants of vinorelbine resistance in BRAF(V600E) mutated chemorefractory metastatic colorectal cancer patients
Journal Articles

Abstract LB-245: Multiple DNA-damage response pathways are modulated by RANBP9 protein in NSCLC

Free
Anna Tessari, Kareesma Parbhoo, Meghan Pawlikowski, Matteo Fassan, Eliana Rulli, Claudia Foray, Alessandra Fabbri, Valerio Embrione, Monica Ganzinelli, Marina Capece, Massimo Broggini, Gabriella Farina, Mirko Marabese, Marina C. Garassino, Carlo Croce, Dario Palmieri, Vincenzo Coppola
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-245.
https://doi.org/10.1158/1538-7445.AM2018-LB-245
Published: 01 July 2018
View articletitled, Abstract LB-245: Multiple DNA-damage response pathways are modulated by RANBP9 protein in NSCLC