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Journal Articles

Abstract 7377: Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

Cancer Res (2024) 84 (6_Supplement): 7377.

https://doi.org/10.1158/1538-7445.AM2024-7377

Published: 22 March 2024

View article titled, Abstract 7377: Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

Journal Articles

Abstract 2940: Use of NK humanized mouse models for the in vivo evaluation of anti-tumor NK-cell therapies

Pauline Rettman, Laure-Marie Meyer, Ravi Rangara, Anna Ponchet-Lac, Nicolas Moindrot, Angélique Biancotto, Céline Lefranc, Fabien Delahaye, Emilia Rabia, Matteo Cesaroni, Sukhvinder Sidhu, Céline Nicolazzi

Cancer Res (2023) 83 (7_Supplement): 2940.

https://doi.org/10.1158/1538-7445.AM2023-2940

Published: 04 April 2023

View article titled, Abstract 2940: Use of NK humanized mouse models for the <em>in vivo</em> evaluation of anti-tumor NK-cell therapies

Journal Articles

Abstract 3367: Tumor-derived Extracellular Vesicles as a potential PD biomarker for TEAD central pocket binder activity in liquid biopsy

Manoel Nunes, Emmanuel Spanakis, Wilson Dos-Santos-Bele, Emilia Rabia, Stephane Soubigou, Gaelle Muzard, Odette Dos-Santos, Jack Pollard, Angela Hadjipanayis, Fabien Delahaye, Olivier Venier, Laurent Debussche, Don Jackson, Colette Dib, Iris Valtingojer, Matteo Cesaroni

Cancer Res (2023) 83 (7_Supplement): 3367.

https://doi.org/10.1158/1538-7445.AM2023-3367

Published: 04 April 2023

View article titled, Abstract 3367: Tumor-derived Extracellular Vesicles as a potential PD biomarker for TEAD central pocket binder activity in liquid biopsy

Journal Articles

Transcriptional Selectivity of Epigenetic Therapy in Cancer

Takahiro Sato, Matteo Cesaroni, Woonbok Chung, Shoghag Panjarian, Anthony Tran, Jozef Madzo, Yasuyuki Okamoto, Hanghang Zhang, Xiaowei Chen, Jaroslav Jelinek, Jean-Pierre J. Issa

Cancer Res (2017) 77 (2): 470–481.

https://doi.org/10.1158/0008-5472.CAN-16-0834

Published: 16 January 2017

View article titled, Transcriptional Selectivity of Epigenetic Therapy in Cancer

Includes: Supplementary data

Journal Articles

Abstract 2779: A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Andrew D. Kelly, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Sijia Yu, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi, Hagop M. Kantarjain, Jaroslav Jelinek, Jean-Pierre J. Issa

Cancer Res (2016) 76 (14_Supplement): 2779.

https://doi.org/10.1158/1538-7445.AM2016-2779

Published: 15 July 2016

View article titled, Abstract 2779: A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Journal Articles

Abstract LB-204: Neoadjuvant Ezh2 inhibition amplifies an inflammatory program and sensitizes Kras-driven NSCLC to anti-NF-κB inhibition

Michela Serresi, Bjorn Siteur, Matteo Cesaroni, Natalie Proost, Danielle Hulsman, Maarten van Lohuizen, Gaetano Gargiulo

Cancer Res (2016) 76 (14_Supplement): LB-204.

https://doi.org/10.1158/1538-7445.AM2016-LB-204

Published: 15 July 2016

View article titled, Abstract LB-204: Neoadjuvant Ezh2 inhibition amplifies an inflammatory program and sensitizes Kras-driven NSCLC to anti-NF-κB inhibition

Journal Articles

Abstract 2657: Target specificity of epigenetic therapy in cancer

Takahiro Sato, Matteo Cesaroni, Shoghag Panjarian, Anthony Tran, Jozef Madzo, Yasuyuki Okamoto, Hanghang Zhang, Xiaowei Chen, Jaroslav Jelinek, Jean-Pierre J. Issa

Cancer Res (2016) 76 (14_Supplement): 2657.

https://doi.org/10.1158/1538-7445.AM2016-2657

Published: 15 July 2016

View article titled, Abstract 2657: Target specificity of epigenetic therapy in cancer

Journal Articles

Abstract B42: Decitabine specifically targets genes that gain DNA methylation and lose expression in cancer and can be combined with histone methylation inhibitors for increased efficacy

Takahiro Sato, Matteo Cesaroni, Anthony Tran, Jozef Madzo, Yasuyuki Okamoto, Hanghang Zhang, Shoghag Panjarian, Jaroslav Jelinek, Jean-Pierre Issa

Cancer Res (2016) 76 (2_Supplement): B42.

https://doi.org/10.1158/1538-7445.CHROMEPI15-B42

Published: 14 January 2016

View article titled, Abstract B42: Decitabine specifically targets genes that gain DNA methylation and lose expression in cancer and can be combined with histone methylation inhibitors for increased efficacy

Journal Articles

Abstract 3521: Combined targeting of DNA and histone methylation improves the efficacy and specificity of epigenetic therapy

Takahiro Sato, Matteo Cesaroni, Jaroslav Jelinek, Jean-Pierre Issa

Cancer Res (2015) 75 (15_Supplement): 3521.

https://doi.org/10.1158/1538-7445.AM2015-3521

Published: 01 August 2015

View article titled, Abstract 3521: Combined targeting of DNA and histone methylation improves the efficacy and specificity of epigenetic therapy

Journal Articles

Abstract 2889: Distinct microbiome in colorectal cancers with the CpG Island Methylator Phenotype

Ang Sun, Matteo Cesaroni, Christian Jobin, Carlos Barrero, Jaroslav Jelinek, Jacqueline D. Sautter, Thomas E. Rams, Salim Merali, Jean-Pierre Issa

Cancer Res (2015) 75 (15_Supplement): 2889.

https://doi.org/10.1158/1538-7445.AM2015-2889

Published: 01 August 2015

View article titled, Abstract 2889: Distinct microbiome in colorectal cancers with the CpG Island Methylator Phenotype

Journal Articles

Abstract 2954: Low level methylation (1-20%) or methylation seeds is a distinct epigenetic regulator of gene expression and is a strong predictor of methylation gains in AML and MDS patients

Priyanka Madireddi, Jaroslav Jelinek, Justin Lee, Matteo Cesaroni, Rodrigo Rodrigues, Yan Zhang, Jean-Pierre Issa

Cancer Res (2015) 75 (15_Supplement): 2954.

https://doi.org/10.1158/1538-7445.AM2015-2954

Published: 01 August 2015

View article titled, Abstract 2954: Low level methylation (1-20%) or methylation seeds is a distinct epigenetic regulator of gene expression and is a strong predictor of methylation gains in AML and MDS patients

Journal Articles

Abstract 5302: Genome-wide methylation analysis reveals multiple epigenetic subtypes of acute myeloid leukemia

Andrew D. Kelly, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi, Hagop M. Kantarjian, Jaroslav Jelinek, Jean-Pierre J. Issa

Cancer Res (2015) 75 (15_Supplement): 5302.

https://doi.org/10.1158/1538-7445.AM2015-5302

Published: 01 August 2015

View article titled, Abstract 5302: Genome-wide methylation analysis reveals multiple epigenetic subtypes of acute myeloid leukemia

Journal Articles

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor–Binding Sites in Chronic Myelomonocytic Leukemia

Jumpei Yamazaki, Jaroslav Jelinek, Yue Lu, Matteo Cesaroni, Jozef Madzo, Frank Neumann, Rong He, Rodolphe Taby, Aparna Vasanthakumar, Trisha Macrae, Kelly R. Ostler, Hagop M. Kantarjian, Shoudan Liang, Marcos R. Estecio, Lucy A. Godley, Jean-Pierre J. Issa

Cancer Res (2015) 75 (14): 2833–2843.

https://doi.org/10.1158/0008-5472.CAN-14-0739

Published: 14 July 2015

View article titled, <em>TET2</em> Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor–Binding Sites in Chronic Myelomonocytic Leukemia

Includes: Supplementary data

Journal Articles

Abstract 373: An siRNA screen identifies CHD4 as a target for epigenetic therapy

Yasuyuki Okamoto, Jumpei Yamazaki, Takahiro Sato, Matteo Cesaroni, Woonbok Chung, Judith Garriga, Jaroslav Jelinek, Richard A Katz, Jean-Pierre Issa

Cancer Res (2014) 74 (19_Supplement): 373.

https://doi.org/10.1158/1538-7445.AM2014-373

Published: 01 October 2014

View article titled, Abstract 373: An siRNA screen identifies CHD4 as a target for epigenetic therapy

Journal Articles

Abstract 2302: CpG hypermethylation marks potentially curable acute myeloid leukemia

Jaroslav Jelinek, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi-Kashani, Hagop M. Kantarjian, Jean-Pierre J. Issa

Cancer Res (2014) 74 (19_Supplement): 2302.

https://doi.org/10.1158/1538-7445.AM2014-2302

Published: 01 October 2014

View article titled, Abstract 2302: CpG hypermethylation marks potentially curable acute myeloid leukemia

Journal Articles

Abstract 413: Validation of methylation biomarkers that distinguish normal colon mucosa from cancer patients from normal colon mucosa of patients without cancer

Matteo Cesaroni

Cancer Res (2014) 74 (19_Supplement): 413.

https://doi.org/10.1158/1538-7445.AM2014-413

Published: 01 October 2014

View article titled, Abstract 413: Validation of methylation biomarkers that distinguish normal colon mucosa from cancer patients from normal colon mucosa of patients without cancer

Journal Articles

Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53

Silvia Licciulli, Jacqueline L. Avila, Linda Hanlon, Scott Troutman, Matteo Cesaroni, Smitha Kota, Brian Keith, M. Celeste Simon, Ellen Puré, Fred Radtke, Anthony J. Capobianco, Joseph L. Kissil

Cancer Res (2013) 73 (19): 5974–5984.

https://doi.org/10.1158/0008-5472.CAN-13-1384

Published: 01 October 2013

View article titled, Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53

Includes: Supplementary data

Journal Articles

RaLP, a New Member of the Src Homology and Collagen Family, Regulates Cell Migration and Tumor Growth of Metastatic Melanomas

Ernesta Fagiani, Giuseppina Giardina, Lucilla Luzi, Matteo Cesaroni, Micaela Quarto, Maria Capra, Giovanni Germano, Maria Bono, Manuela Capillo, PierGiuseppe Pelicci, Luisa Lanfrancone

Cancer Res (2007) 67 (7): 3064–3073.

https://doi.org/10.1158/0008-5472.CAN-06-2301

Published: 04 April 2007

View article titled, RaLP, a New Member of the Src Homology and Collagen Family, Regulates Cell Migration and Tumor Growth of Metastatic Melanomas

Includes: Supplementary data

NARROW

Abstract 7377: Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

Abstract 2940: Use of NK humanized mouse models for the in vivo evaluation of anti-tumor NK-cell therapies

Abstract 3367: Tumor-derived Extracellular Vesicles as a potential PD biomarker for TEAD central pocket binder activity in liquid biopsy

Transcriptional Selectivity of Epigenetic Therapy in Cancer

Abstract 2779: A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Abstract LB-204: Neoadjuvant Ezh2 inhibition amplifies an inflammatory program and sensitizes Kras-driven NSCLC to anti-NF-κB inhibition

Abstract 2657: Target specificity of epigenetic therapy in cancer

Abstract B42: Decitabine specifically targets genes that gain DNA methylation and lose expression in cancer and can be combined with histone methylation inhibitors for increased efficacy

Abstract 3521: Combined targeting of DNA and histone methylation improves the efficacy and specificity of epigenetic therapy

Abstract 2889: Distinct microbiome in colorectal cancers with the CpG Island Methylator Phenotype

Abstract 2954: Low level methylation (1-20%) or methylation seeds is a distinct epigenetic regulator of gene expression and is a strong predictor of methylation gains in AML and MDS patients

Abstract 5302: Genome-wide methylation analysis reveals multiple epigenetic subtypes of acute myeloid leukemia

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor–Binding Sites in Chronic Myelomonocytic Leukemia

Abstract 373: An siRNA screen identifies CHD4 as a target for epigenetic therapy

Abstract 2302: CpG hypermethylation marks potentially curable acute myeloid leukemia

Abstract 413: Validation of methylation biomarkers that distinguish normal colon mucosa from cancer patients from normal colon mucosa of patients without cancer

Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53

RaLP, a New Member of the Src Homology and Collagen Family, Regulates Cell Migration and Tumor Growth of Metastatic Melanomas

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