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Massimo Santoro
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Journal Articles

Retraction: Suppression of HMGA2 Protein Synthesis Could Be a Tool for the Therapy of Well Differentiated Liposarcomas Overexpressing HMGA2

Francesca Pentimalli, Monica Dentice, Monica Fedele, Giovanna Maria Pierantoni, Letizia Cito, Pierlorenzo Pallante, Massimo Santoro, Giuseppe Viglietto, Paola Dal Cin, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6909.
https://doi.org/10.1158/0008-5472.CAN-18-3458
Published: 13 December 2018
View article titled, Retraction: Suppression of HMGA2 Protein Synthesis Could Be a Tool for the Therapy of Well Differentiated Liposarcomas Overexpressing <em>HMGA2</em>
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Journal Articles

Retraction: Overexpression of Proteins HMGA1 Induces Cell Cycle Deregulation and Apoptosis in Normal Rat Thyroid Cells

Monica Fedele, Giovanna Maria Pierantoni, Maria Teresa Berlingieri, Sabrina Battista, Gustavo Baldassarre, Nikhil Munshi, Monica Dentice, Dimitris Thanos, Massimo Santoro, Giuseppe Viglietto, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6910.
https://doi.org/10.1158/0008-5472.CAN-18-3460
Published: 13 December 2018
View article titled, Retraction: Overexpression of Proteins HMGA1 Induces Cell Cycle Deregulation and Apoptosis in Normal Rat Thyroid Cells
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Journal Articles

Retraction: The Receptor-Type Protein Tyrosine Phosphatase J Antagonizes the Biochemical and Biological Effects of RET-Derived Oncoproteins

Angela Iervolino, Rodolfo Iuliano, Francesco Trapasso, Giuseppe Viglietto, Rosa Marina Melillo, Francesca Carlomagno, Massimo Santoro, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6907.
https://doi.org/10.1158/0008-5472.CAN-18-3456
Published: 13 December 2018
View article titled, Retraction: The Receptor-Type Protein Tyrosine Phosphatase J Antagonizes the Biochemical and Biological Effects of RET-Derived Oncoproteins
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Journal Articles

CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells

Valentina De Falco, Anna Tamburrino, Simona Ventre, Maria Domenica Castellone, Mouhannad Malek, Serge N. Manié, Massimo Santoro
Journal: Cancer Research
Cancer Res (2012) 72 (6): 1449–1458.
https://doi.org/10.1158/0008-5472.CAN-11-3320
Published: 14 March 2012
View article titled, CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
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Includes: Supplementary data
Journal Articles

Is Co-option a Prevailing Mechanism during Cancer Progression?

Marc Billaud, Massimo Santoro
Journal: Cancer Research
Cancer Res (2011) 71 (21): 6572–6575.
https://doi.org/10.1158/0008-5472.CAN-11-2158
Published: 30 October 2011
View article titled, Is Co-option a Prevailing Mechanism during Cancer Progression?
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Journal Articles

The β-Catenin Axis Integrates Multiple Signals Downstream from RET/Papillary Thyroid Carcinoma Leading to Cell Proliferation

Maria Domenica Castellone, Valentina De Falco, Deva Magendra Rao, Roberto Bellelli, Magesh Muthu, Fulvio Basolo, Alfredo Fusco, J. Silvio Gutkind, Massimo Santoro
Journal: Cancer Research
Cancer Res (2009) 69 (5): 1867–1876.
https://doi.org/10.1158/0008-5472.CAN-08-1982
Published: 02 March 2009
View article titled, The β-Catenin Axis Integrates Multiple Signals Downstream from RET/Papillary Thyroid Carcinoma Leading to Cell Proliferation
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Journal Articles

Identification of Polo-like Kinase 1 as a Potential Therapeutic Target in Anaplastic Thyroid Carcinoma

Tito Claudio Nappi, Paolo Salerno, Horst Zitzelsberger, Francesca Carlomagno, Giuliana Salvatore, Massimo Santoro
Journal: Cancer Research
Cancer Res (2009) 69 (5): 1916–1923.
https://doi.org/10.1158/0008-5472.CAN-08-1693
Published: 02 March 2009
View article titled, Identification of Polo-like Kinase 1 as a Potential Therapeutic Target in Anaplastic Thyroid Carcinoma
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Includes: Supplementary data
Journal Articles

Loss of the CBX7 Gene Expression Correlates with a Highly Malignant Phenotype in Thyroid Cancer

Pierlorenzo Pallante, Antonella Federico, Maria Teresa Berlingieri, Mimma Bianco, Angelo Ferraro, Floriana Forzati, Antonino Iaccarino, Maria Russo, Giovanna Maria Pierantoni, Vincenza Leone, Silvana Sacchetti, Giancarlo Troncone, Massimo Santoro, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2008) 68 (16): 6770–6778.
https://doi.org/10.1158/0008-5472.CAN-08-0695
Published: 12 August 2008
View article titled, Loss of the <em>CBX7</em> Gene Expression Correlates with a Highly Malignant Phenotype in Thyroid Cancer
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Includes: Supplementary data
Journal Articles

Biological Role and Potential Therapeutic Targeting of the Chemokine Receptor CXCR4 in Undifferentiated Thyroid Cancer

Valentina De Falco, Valentina Guarino, Elvira Avilla, Maria Domenica Castellone, Paolo Salerno, Giuliana Salvatore, Pinuccia Faviana, Fulvio Basolo, Massimo Santoro, Rosa Marina Melillo
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11821–11829.
https://doi.org/10.1158/0008-5472.CAN-07-0899
Published: 18 December 2007
View article titled, Biological Role and Potential Therapeutic Targeting of the Chemokine Receptor CXCR4 in Undifferentiated Thyroid Cancer
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Journal Articles

Cytosolic Phospholipase A2α Regulates Cell Growth in RET/PTC-Transformed Thyroid Cells

Stefania Mariggiò, Beatrice Maria Filippi, Cristiano Iurisci, Luana Katia Dragani, Valentina De Falco, Massimo Santoro, Daniela Corda
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11769–11778.
https://doi.org/10.1158/0008-5472.CAN-07-1997
Published: 18 December 2007
View article titled, Cytosolic Phospholipase A<sub>2</sub>α Regulates Cell Growth in <em>RET/PTC</em>-Transformed Thyroid Cells
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Journal Articles

A Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid Carcinoma

Giuliana Salvatore, Tito Claudio Nappi, Paolo Salerno, Yuan Jiang, Corrado Garbi, Clara Ugolini, Paolo Miccoli, Fulvio Basolo, Maria Domenica Castellone, Anna Maria Cirafici, Rosa Marina Melillo, Alfredo Fusco, Michael L. Bittner, Massimo Santoro
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10148–10158.
https://doi.org/10.1158/0008-5472.CAN-07-1887
Published: 01 November 2007
View article titled, A Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid Carcinoma
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Includes: Supplementary data
Journal Articles

The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells

Nagako Akeno-Stuart, Michelle Croyle, Jeffrey A. Knauf, Roberta Malaguarnera, Donata Vitagliano, Massimo Santoro, Christine Stephan, Konstantina Grosios, Markus Wartmann, Robert Cozens, Giorgio Caravatti, Doriano Fabbro, Heidi A. Lane, James A. Fagin
Journal: Cancer Research
Cancer Res (2007) 67 (14): 6956–6964.
https://doi.org/10.1158/0008-5472.CAN-06-4605
Published: 17 July 2007
View article titled, The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells
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Journal Articles

PIK3CA gene copy number in 116 thyroid carcinomas and 17 thyroid cancer cell lines

Virginia Lopez Martinez, Angela M. Costa, Giuliana Salvatore, Agustin Herrero, Jose Cameselle-Teijeiro, Massimo Santoro, Ginesa Garcia-Rostan
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 265.
Published: 01 May 2007
View article titled, <em>PIK3CA</em> gene copy number in 116 thyroid carcinomas and 17 thyroid cancer cell lines
Journal Articles

RET/Papillary Thyroid Carcinoma Oncogenic Signaling through the Rap1 Small GTPase

Valentina De Falco, Maria Domenica Castellone, Gabriella De Vita, Anna Maria Cirafici, Jerome M. Hershman, Carmen Guerrero, Alfredo Fusco, Rosa Marina Melillo, Massimo Santoro
Journal: Cancer Research
Cancer Res (2007) 67 (1): 381–390.
https://doi.org/10.1158/0008-5472.CAN-06-0981
Published: 08 January 2007
View article titled, RET/Papillary Thyroid Carcinoma Oncogenic Signaling through the Rap1 Small GTPase
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Journal Articles

The Receptor-Type Protein Tyrosine Phosphatase J Antagonizes the Biochemical and Biological Effects of RET-Derived Oncoproteins

Angela Iervolino, Rodolfo Iuliano, Francesco Trapasso, Giuseppe Viglietto, Rosa Marina Melillo, Francesca Carlomagno, Massimo Santoro, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6280–6287.
https://doi.org/10.1158/0008-5472.CAN-06-0228
Published: 15 June 2006
View article titled, The Receptor-Type Protein Tyrosine Phosphatase J Antagonizes the Biochemical and Biological Effects of RET-Derived Oncoproteins
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Journal Articles

Mutation of the PIK3CA Gene in Anaplastic Thyroid Cancer

Ginesa García-Rostán, Angela M. Costa, Isabel Pereira-Castro, Giuliana Salvatore, Radhames Hernandez, Mario J.A. Hermsem, Agustin Herrero, Alfredo Fusco, Jose Cameselle-Teijeiro, Massimo Santoro
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10199–10207.
https://doi.org/10.1158/0008-5472.CAN-04-4259
Published: 15 November 2005
View article titled, Mutation of the <em>PIK3CA</em> Gene in Anaplastic Thyroid Cancer
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Journal Articles

Regulation of p27Kip1 Protein Levels Contributes to Mitogenic Effects of the RET/PTC Kinase in Thyroid Carcinoma Cells

Donata Vitagliano, Francesca Carlomagno, Maria Letizia Motti, Giuseppe Viglietto, Yuri E. Nikiforov, Marina N. Nikiforova, Jerome M. Hershman, Anderson J. Ryan, Alfredo Fusco, Rosa Marina Melillo, Massimo Santoro
Journal: Cancer Research
Cancer Res (2004) 64 (11): 3823–3829.
https://doi.org/10.1158/0008-5472.CAN-03-3918
Published: 01 June 2004
View article titled, Regulation of p27Kip1 Protein Levels Contributes to Mitogenic Effects of the RET/PTC Kinase in Thyroid Carcinoma Cells
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Journal Articles

Suppression of HMGA2 Protein Synthesis Could Be a Tool for the Therapy of Well Differentiated Liposarcomas Overexpressing HMGA2

Francesca Pentimalli, Monica Dentice, Monica Fedele, Giovanna Maria Pierantoni, Letizia Cito, Pierlorenzo Pallante, Massimo Santoro, Giuseppe Viglietto, Paola Dal Cin, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2003) 63 (21): 7423–7427.
Published: 11 November 2003
View article titled, Suppression of HMGA2 Protein Synthesis Could Be a Tool for the Therapy of Well Differentiated Liposarcomas Overexpressing <em>HMGA2</em>
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Journal Articles

An Adenovirus Carrying the Rat Protein Tyrosine Phosphatase η Suppresses the Growth of Human Thyroid Carcinoma Cell Lines in Vitro and in Vivo

Rodolfo Iuliano, Francesco Trapasso, Ilaria Le Pera, Filippo Schepis, Irene Samà, Alessandra Clodomiro, Kristoffel R. Dumon, Massimo Santoro, Lorenzo Chiariotti, Giuseppe Viglietto, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2003) 63 (4): 882–886.
Published: 15 February 2003
View article titled, An Adenovirus Carrying the Rat Protein Tyrosine Phosphatase η Suppresses the Growth of Human Thyroid Carcinoma Cell Lines <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

ZD6474, an Orally Available Inhibitor of KDR Tyrosine Kinase Activity, Efficiently Blocks Oncogenic RET Kinases

Francesca Carlomagno, Donata Vitagliano, Teresa Guida, Fortunato Ciardiello, Giampaolo Tortora, Giancarlo Vecchio, Anderson J. Ryan, Gabriella Fontanini, Alfredo Fusco, Massimo Santoro
Journal: Cancer Research
Cancer Res (2002) 62 (24): 7284–7290.
Published: 15 December 2002
View article titled, ZD6474, an Orally Available Inhibitor of KDR Tyrosine Kinase Activity, Efficiently Blocks Oncogenic RET Kinases
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