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Massimo Libra
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Journal Articles

Abstract 1700: Clonal emergence of resistance to methotrexate in osteosarcoma barcoded PDX cells

Giuseppe Longo, Sylvester Jusu, Zhongting Zhang, Zhaohui Xu, Wendong Zhang, Michael Roth, Rui Yang, Douglas Harrison, Massimo Libra, Amer Najjar, Jonathan Gill, Richard Gorlick
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1700.
https://doi.org/10.1158/1538-7445.AM2023-1700
Published: 04 April 2023
View articletitled, Abstract 1700: Clonal emergence of resistance to methotrexate in osteosarcoma barcoded PDX cells
Journal Articles

Abstract 4687: Oncogenic role of the transcription factor YY1 and its target Survivin in non-Hodgkin's lymphoma

Silvia Vivarelli, Luca Falzone, Saverio Candido, Benjamin Bonavida, Massimo Libra
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4687.
https://doi.org/10.1158/1538-7445.AM2020-4687
Published: 15 August 2020
View articletitled, Abstract 4687: Oncogenic role of the transcription factor YY1 and its target Survivin in non-Hodgkin's lymphoma
Journal Articles

Abstract 2400: Strong biological bias for ALK intron 19 breakpoints in NSCLC

Giulia C. Leonardi, Taek-Chin Cheong, Chiara Ambrogio, Tao Chen, Wei-Tien Tai, Elif Karaca, Ines Mota, Massimo Libra, Mark M. Awad, Rafael Blasco-Patino, Roberto Chiarle
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2400.
https://doi.org/10.1158/1538-7445.AM2020-2400
Published: 15 August 2020
View articletitled, Abstract 2400: Strong biological bias for ALK intron 19 breakpoints in NSCLC
Journal Articles

Abstract 4836: Diagnostic and prognostic significance of microRNA modulation in oral cancer

Luca Falzone, Silvia Vivarelli, Salvatore Crimi, Alberto Bianchi, Saverio Candido, Massimo Libra
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4836.
https://doi.org/10.1158/1538-7445.AM2020-4836
Published: 15 August 2020
View articletitled, Abstract 4836: Diagnostic and prognostic significance of microRNA modulation in oral cancer
Journal Articles

Abstract 5305: DNA methylation and gene expression in melanoma: A large-scale integrated analysis

Saverio Candido, Giuseppe A. Parasiliti Palumbo, Giulia Russo, Luca Falzone, Giulia C. Leonardi, Francesco Pappalardo, Massimo Libra
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5305.
https://doi.org/10.1158/1538-7445.AM2018-5305
Published: 01 July 2018
View articletitled, Abstract 5305: DNA methylation and gene expression in melanoma: A large-scale integrated analysis
Journal Articles

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling

Marco Donia, Katja Harbst, Marit van Buuren, Pia Kvistborg, Mattias F. Lindberg, Rikke Andersen, Manja Idorn, Shamaila Munir Ahmad, Eva Ellebæk, Anja Mueller, Paolo Fagone, Ferdinando Nicoletti, Massimo Libra, Martin Lauss, Sine Reker Hadrup, Henrik Schmidt, Mads Hald Andersen, Per thor Straten, Jonas A. Nilsson, Ton N. Schumacher, Barbara Seliger, Göran Jönsson, Inge Marie Svane
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4562–4566.
https://doi.org/10.1158/0008-5472.CAN-16-3172
Published: 31 August 2017
View articletitled, Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling
Open the PDF for Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 4304: MMP-9 as a marker of response to treatment with B-Raf inhibitors in cutaneous melanoma

Saverio Candido, Grazia Malaponte, Rossella Salemi, Franca Maria Pezzino, Aurora Scalisi, James A. McCubrey, Massimo Libra
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4304.
https://doi.org/10.1158/1538-7445.AM2015-4304
Published: 01 August 2015
View articletitled, Abstract 4304: MMP-9 as a marker of response to treatment with B-Raf inhibitors in cutaneous melanoma
Journal Articles

Abstract 4074: Transcription factors involved in the genesis and progression of cancer differently modulated by transforming growth factor-beta3 (TGF-Beta3) in prostate cell lines.

Silvia Caggia, Saverio Candido, Massimo Libra, Venera Cardile
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4074.
https://doi.org/10.1158/1538-7445.AM2013-4074
Published: 15 April 2013
View articletitled, Abstract 4074: Transcription factors involved in the genesis and progression of cancer differently modulated by transforming growth factor-beta3 (TGF-Beta3) in prostate cell lines.
Journal Articles

Abstract 4197: Discovering FUS-CHOP targets: A Chip-Seq approach

Elena Tonin, Francesco G. Sirocco, Sabrina Rossi, Angelo Paolo Dei Tos, Massimo Libra, Gregory J. Hannon, Roberta Maestro
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4197.
https://doi.org/10.1158/1538-7445.AM2012-4197
Published: 15 April 2012
View articletitled, Abstract 4197: Discovering FUS-CHOP targets: A Chip-Seq approach
Journal Articles

Abstract 5263: Osteopontin/matrixmetalloproteinasis pathway activation in head and neck cancer

Bibiana Bruni, Massimo Libra, M. Clorinda Mazzzarino, Grazia Malaponte, Franca Stivala
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5263.
https://doi.org/10.1158/1538-7445.AM2011-5263
Published: 15 April 2011
View articletitled, Abstract 5263: Osteopontin/matrixmetalloproteinasis pathway activation in head and neck cancer
Journal Articles

Abstract 332: B-Raf mutations are associated with a worse outcome in ovarian cancer

Massimo Libra, Alessia E. Russo, Ilenia Pellizzari, Marina Bagnoli, Francesco Raspagliesi, Roberto Sorio, Gustavo Baldassarre, Silvana Canevari, M.I.T.O. Group
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 332.
https://doi.org/10.1158/1538-7445.AM2011-332
Published: 15 April 2011
View articletitled, Abstract 332: B-Raf mutations are associated with a worse outcome in ovarian cancer
Journal Articles

Abstract #559: miRNA profiles associated to clinical response in advanced stage ovarian cancer patients

Loris De Cecco, Marina Bagnoli, Giancarlo Castellano, Paola Perego, Paola Alberti, Edoardo Marchesi, Massimo Libra, Roberto Sorio, Francesco Raspagliesi, Delia Mezzanzanica, Silvana Canevari
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 559.
Published: 01 May 2009
View articletitled, Abstract #559: miRNA profiles associated to clinical response in advanced stage ovarian cancer patients
Journal Articles

Abstract #2752: Activation of MAPK and AKT pathways in melanoma development by B-Raf and PI3KCA mutations

Massimo Libra, Grazia Malaponte, Bevelacqua Ylenia, Bibiana Bruni, Maria Mazzarino, James McCubrey, Franca Stivala
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2752.
Published: 01 May 2009
View articletitled, Abstract #2752: Activation of MAPK and AKT pathways in melanoma development by B-Raf and PI3KCA mutations
Journal Articles

Integrated computational and experimental analysis of osteopontin and matrix metalloproteinases in non-hodgkin lymphoma

Massimo Libra, Giancarlo Castellano, Grazia Malaponte, Loredana Militello, Silvana Canevari, Maria Mazzarino, Franca Stivala
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2214.
Published: 01 May 2008
View articletitled, Integrated computational and experimental analysis of osteopontin and matrix metalloproteinases in non-hodgkin lymphoma
Journal Articles

The Akt/Mammalian Target of Rapamycin Signal Transduction Pathway Is Activated in High-Risk Myelodysplastic Syndromes and Influences Cell Survival and Proliferation

Matilde Y. Follo, Sara Mongiorgi, Costanza Bosi, Alessandra Cappellini, Carlo Finelli, Francesca Chiarini, Veronica Papa, Massimo Libra, Giovanni Martinelli, Lucio Cocco, Alberto M. Martelli
Journal: Cancer Research
Cancer Res (2007) 67 (9): 4287–4294.
https://doi.org/10.1158/0008-5472.CAN-06-4409
Published: 04 May 2007
View articletitled, The Akt/Mammalian Target of Rapamycin Signal Transduction Pathway Is Activated in High-Risk Myelodysplastic Syndromes and Influences Cell Survival and Proliferation
Open the PDF for The Akt/Mammalian Target of Rapamycin Signal Transduction Pathway Is Activated in High-Risk Myelodysplastic Syndromes and Influences Cell Survival and Proliferation in another window
Journal Articles

Activation of MAPK and AKT pathways by BRAF, NRAS and PIK3CA mutations in melanoma

Massimo Libra, Grazia Malaponte, Giovanni Ligresti, Pietro Gangemi, Roberta Siciliano, Salvatore Travali, Maria Mazzarino, Katia Mangano, Ferdinando Nicoletti, Ellis Wong, Linda Steelman, James McCubrey, Franca Stivala
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 155.
Published: 01 May 2007
View articletitled, Activation of MAPK and AKT pathways by BRAF, NRAS and PIK3CA mutations in melanoma
Journal Articles

Inhibition of PTEN function increases chemotherapeutic drug and ionizing radiation resistance in breast cancer

William Chappell, Linda Steelman, Stephen Abrams, Ellis Wong, Brian Lehmann, David Terrian, Nick Leslie, Peter Downes, Alberto Martelli, Franca Stivala, Massimo Libra, Patrick Navolanic, James McCubrey
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 272.
Published: 01 May 2007
View articletitled, Inhibition of PTEN function increases chemotherapeutic drug and ionizing radiation resistance in breast cancer
Journal Articles

Correlation between overexpression of YY1 and downregulation of DR5 in prostate tumor arrays: novel mechanism of escape from immune surveillance

Sara Huerta-Yepez, Angeles Hernandez-Cueto, Mario Vega, Berenice Sanchez-Arellano, David Garcia-Herrera, Daniel Hernandez-Cueto, Cesar Gonzalez-Bonilla, Stavroula Baritaki, Massimo Libra, Benjamin Bonavida
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2400.
Published: 01 May 2007
View articletitled, Correlation between overexpression of YY1 and downregulation of DR5 in prostate tumor arrays: novel mechanism of escape from immune surveillance
Journal Articles

Analysis of BRAF, NRAS and PI3K mutation in primary and metastatic melanoma

Massimo Libra, Grazia Malaponte, Daniela Callari, Antonio D’Assoro, Salvatore Travali, Maria C Mazzarino, James A. McCubrey, Franca Stivala
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 306.
Published: 15 April 2006
View articletitled, Analysis of BRAF, NRAS and PI3K mutation in primary and metastatic melanoma
Journal Articles

Characteristics of rituximab-resistant B-NHL clones: deficiencies in rituximab-mediated changes in lipid raft microdomains and cell signaling

Ali R. Jazirehi, Christine Bezombes, Guy Laurant, Massimo Libra, Benjamin Bonavida
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1094.
Published: 15 April 2006
View articletitled, Characteristics of rituximab-resistant B-NHL clones: deficiencies in rituximab-mediated changes in lipid raft microdomains and cell signaling