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Masayuki Watanabe
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Journal Articles

Abstract 4340: RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk

Takatsugu Ishimoto, Keisuke Miyake, Masakazu Yashiro, Tsugio Eto, Daisuke Izumi, Kota Arima, Yoshifumi Baba, Masayuki Watanabe, Kosei Hirakawa, Hideo Baba, Patrick Tan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4340.
https://doi.org/10.1158/1538-7445.AM2017-4340
Published: 01 July 2017
View article titled, Abstract 4340: RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk
Journal Articles

Abstract 423: CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasive ability in gastric cancer

Daisuke Izumi, Takatsugu Ishimoto, Hidetaka Sugihara, Eto Kojiro, Hiroshi Sawayama, Keisuke Miyake, Yuki Kiyozumi, Keisuke Kosumi, Ryuma Tokunaga, Kazuto Harada, Junji Kurashige, Masaaki Iwatsuki, Shiro Iwagami, Yoshifumi Baba, Yasuo Sakamoto, Yuji Miyamoto, Naoya Yoshida, Masayuki Watanabe, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 423.
https://doi.org/10.1158/1538-7445.AM2015-423
Published: 01 August 2015
View article titled, Abstract 423: CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasive ability in gastric cancer
Journal Articles

Abstract 3132: Suppressor microRNA-145 is epigenetically regulated by promoter hypermethylation in esophageal squamous cell carcinoma

kazuto harada, Yoshifumi Baba, Keisuke Kosumi, Ryuma Tokunaga, Daisuke Izumi, Mayuko Ouchi, Kennichi Nakamura, Yuki Kiyozumi, Junji Kurashige, Yukiharu Hiyoshi, Shiro Iwagami, Yuji Miyamoato, Yasuo Sakamoto, Naoya Yoshida, Masayuki Watanabe, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3132.
https://doi.org/10.1158/1538-7445.AM2015-3132
Published: 01 August 2015
View article titled, Abstract 3132: Suppressor microRNA-145 is epigenetically regulated by promoter hypermethylation in esophageal squamous cell carcinoma
Journal Articles

Abstract 4829: The clinical significance of APOBEC3B in esophageal squamous cell carcinoma

Keisuke Kosumi, Yoshifumi Baba, Takatsugu Ishimoto, Kenichi Nakamura, Kazuto Harada, Mayuko Ohuchi, Yuki Kiyozumi, Daisuke Izumi, Ryuma Tokunaga, Junji Kurashige, Ryuichi Karashima, Yukiharu Hiyoshi, Shiro Iwagami, Yasuo Sakamoto, Yuji Miyamoto, Naoya Yoshida, Masayuki Watanabe, Hideo Baba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4829.
https://doi.org/10.1158/1538-7445.AM2015-4829
Published: 01 August 2015
View article titled, Abstract 4829: The clinical significance of APOBEC3B in esophageal squamous cell carcinoma
Journal Articles

Abstract 3357: Glucose transporter 1 positivity on primary lesions of esophageal squamous cell carcinoma is associated with hematogenous recurrence

Hiroshi Sawayama, Takatsugu Ishimoto, Masayuki Watanabe, Naoya Yoshida, Yoshifumi Baba, Hidetaka Sugihara, Daisuke Izumi, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3357.
https://doi.org/10.1158/1538-7445.AM2014-3357
Published: 01 October 2014
View article titled, Abstract 3357: Glucose transporter 1 positivity on primary lesions of esophageal squamous cell carcinoma is associated with hematogenous recurrence
Journal Articles

Small Molecule Agonists of PPAR-γ Exert Therapeutic Effects in Esophageal Cancer

Hiroshi Sawayama, Takatsugu Ishimoto, Masayuki Watanabe, Naoya Yoshida, Hidetaka Sugihara, Junji Kurashige, Kotaro Hirashima, Masaaki Iwatsuki, Yoshifumi Baba, Eiji Oki, Masaru Morita, Yoshinobu Shiose, Hideo Baba
Journal: Cancer Research
Cancer Res (2014) 74 (2): 575–585.
https://doi.org/10.1158/0008-5472.CAN-13-1836
Published: 16 January 2014
View article titled, Small Molecule Agonists of PPAR-γ Exert Therapeutic Effects in Esophageal Cancer
Open the PDF for Small Molecule Agonists of PPAR-γ Exert Therapeutic Effects in Esophageal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5350: Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma by regulating cell cycle and apoptosis.

Shigeki Nakagawa, Hirohisa Okabe, Yasuo Sakamoto, Hiromitsu Hayashi, Daisuke Hashimoto, Hideyuki Kuroki, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Masayuki Watanabe, Toru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5350.
https://doi.org/10.1158/1538-7445.AM2013-5350
Published: 15 April 2013
View article titled, Abstract 5350: Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma by regulating cell cycle and apoptosis.
Journal Articles

Abstract 5511: The proliferation-inhibiting effects of Efatutazone, a novel third-generation peroxisome proliferator-activated receptor gamma agonist, on esophageal squamous cell carcinoma in vitro and in vivo.

Hiroshi Sawayama, Takatsugu Ishimoto, Masayuki Watanabe, Naoya Yoshida, Yoshifumi Baba, Masaaki Iwatsuki, Hidetaka Sugihara, Hiroshi Onuma, Yoshinobu Shiose, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5511.
https://doi.org/10.1158/1538-7445.AM2013-5511
Published: 15 April 2013
View article titled, Abstract 5511: The proliferation-inhibiting effects of Efatutazone, a novel third-generation peroxisome proliferator-activated receptor gamma agonist, on esophageal squamous cell carcinoma <em>in vitro</em> and <em>in vivo</em>.
Journal Articles

Abstract 5334: Tumor-associated-macrophage induces CD44 expression through microRNAs suppression promotes cancer progression and chemoresistance.

Takatsugu Ishimoto, Masayuki Watanabe, Nobuyuki Ozaki, Masaaki Iwatsuki, Yoshifumi Baba, Naoya Yoshida, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5334.
https://doi.org/10.1158/1538-7445.AM2013-5334
Published: 15 April 2013
View article titled, Abstract 5334: Tumor-associated-macrophage induces CD44 expression through microRNAs suppression promotes cancer progression and chemoresistance.
Journal Articles

Abstract 4158: MicroRNA-mediated regulation of Bmi1 expression in gastric and colon cancer cells.

Hidetaka Sugihara, Takatsugu Ishimoto, Masayuki Watanabe, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4158.
https://doi.org/10.1158/1538-7445.AM2013-4158
Published: 15 April 2013
View article titled, Abstract 4158: MicroRNA-mediated regulation of Bmi1 expression in gastric and colon cancer cells.
Journal Articles

Abstract 648: Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.

Asuka Murata, Yoshifumi Baba, Masayuki Watanabe, Hironobu Shigaki, Shiro Iwagami, Yasuo Sakamoto, Yuji Miyamoto, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 648.
https://doi.org/10.1158/1538-7445.AM2013-648
Published: 15 April 2013
View article titled, Abstract 648: Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.
Journal Articles

Abstract 2965: Relationship between LINE-1 methylation level, allelic imbalance and PIK3CA mutation in esophageal squamous cell carcinoma.

Yoshifumi Baba, Masayuki Watanabe, Asuka Murata, Hironobu Shigaki, Shiro Iwagami, Masaaki Iwatsuki, Takatsugu Ishimoto, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2965.
https://doi.org/10.1158/1538-7445.AM2013-2965
Published: 15 April 2013
View article titled, Abstract 2965: Relationship between LINE-1 methylation level, allelic imbalance and <em>PIK3CA</em> mutation in esophageal squamous cell carcinoma.
Journal Articles

Abstract 1849: A novel gene-pathway regulating of microRNA mediates resistance to trastuzumab forgastric cancer.

Kojiro Eto, Masayuki Watanabe, Masaaki Iwatsuki, Hideo Baba
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1849.
https://doi.org/10.1158/1538-7445.AM2013-1849
Published: 15 April 2013
View article titled, Abstract 1849: A novel gene-pathway regulating of microRNA mediates resistance to trastuzumab forgastric cancer.
Journal Articles

CD44s Regulates the TGF-β–Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

Kosuke Mima, Hirohisa Okabe, Takatsugu Ishimoto, Hiromitsu Hayashi, Shigeki Nakagawa, Hideyuki Kuroki, Masayuki Watanabe, Toru Beppu, Mayumi Tamada, Osamu Nagano, Hideyuki Saya, Hideo Baba
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3414–3423.
https://doi.org/10.1158/0008-5472.CAN-12-0299
Published: 01 July 2012
View article titled, CD44s Regulates the TGF-β–Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
Open the PDF for CD44s Regulates the TGF-β–Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 4146: The expression of exosomal microRNA in serum of patients with esophageal squamous cell carcinoma

Youhei Tanaka, Masayuki Watanabe, Hidenobu Kamohara, Junji Kurashige, Kousuke Mima, Hirohisa Okabe, Hideo Baba
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4146.
https://doi.org/10.1158/1538-7445.AM2012-4146
Published: 15 April 2012
View article titled, Abstract 4146: The expression of exosomal microRNA in serum of patients with esophageal squamous cell carcinoma
Journal Articles

Abstract 4101: Prognostic significance of LINE-1 mathylation level in gastric cancer

Shiro Iwagami, Yoshifumi Baba, Masayuki Watanabe, Hironobu Shigaki, Keisuke Miyake, Jyunji Kurashige, Takatsugu Ishimoto, Masayuki Iwatsuki, Hideo Baba
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4101.
https://doi.org/10.1158/1538-7445.AM2012-4101
Published: 15 April 2012
View article titled, Abstract 4101: Prognostic significance of LINE-1 mathylation level in gastric cancer
Journal Articles

Abstract 2306: Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in esophageal squamous cell carcinoma

Junji Kurashige, Masayuki Watanabe, Masaaki Iwatsuki, Yoshifumi Baba, Hideo Baba
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2306.
https://doi.org/10.1158/1538-7445.AM2012-2306
Published: 15 April 2012
View article titled, Abstract 2306: Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in esophageal squamous cell carcinoma
Journal Articles

Abstract 915: Serine protease inhibitor Kazal type 1 promote a carcinogenesis of the colon

Satoshi Ida, Masaki Ohmuraya, Masaaki Iwatsuki, Naoko Hayashi, Kei Horino, Masayuki Watanabe, Hiroshi Takamori, Tooru Beppu, Hideo Baba
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 915.
https://doi.org/10.1158/1538-7445.AM2011-915
Published: 15 April 2011
View article titled, Abstract 915: Serine protease inhibitor Kazal type 1 promote a carcinogenesis of the colon
Journal Articles

Abstract 3367: Clinicopathological significances of CD44v6 in colon cancer

Seiya Saitou, Masayuki Watanabe, Hirohisa Okabe, Kouiti Kinoshita, Junji Kurashige, Masaaki Iwatuki, Yoshihumi Baba, Naoko Hayashi, Hideo Baba
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3367.
https://doi.org/10.1158/1538-7445.AM2011-3367
Published: 15 April 2011
View article titled, Abstract 3367: Clinicopathological significances of CD44v6 in colon cancer
Journal Articles

Abstract 1155: Serum microRNA-21 is a novel biomarker in patients with esophageal squamous cell carcinoma

Junji Kurashige, Masayuki Watanabe, Hidenobu Kamohara, Masaaki Iwatsuki, Yukiharu Hiyoshi, Koichi Kinoshita, Seiya Saito, Yoshifumi Baba, Naoko Hayashi, Hideo Baba
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1155.
https://doi.org/10.1158/1538-7445.AM2011-1155
Published: 15 April 2011
View article titled, Abstract 1155: Serum microRNA-21 is a novel biomarker in patients with esophageal squamous cell carcinoma