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Masayuki Nagahashi
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Journal Articles

Abstract PO2-15-09: Immune related cell fraction in peripheral blood and outcomes of advanced breast cancer patients treated with Eribulin

Masayuki Nagahashi, Ayako Bun, Mamiko Kuroiwa, Miki Komatsu, Sayaka Urano, Yukie Fujimoto, Aoi Oshiro, Ayumu Mitsuyoshi, Haruka Kanaoka, Akira Hattori, Reiko Fukui, Tomoko Higuchi, Arisa Nishimukai, Keiko Murase, Yuichi Takatsuka, Yasuo Miyoshi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-15-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-15-09
Published: 02 May 2024
View article titled, Abstract PO2-15-09: Immune related cell fraction in peripheral blood and outcomes of advanced breast cancer patients treated with Eribulin
Journal Articles

Abstract PO2-06-04: Prospective study on eribulin efficacy in advanced and metastatic breast cancer: changes in TGF-β compared to other standard chemotherapy agents (KBCSG-TR 2018, POTENTIAL)

Takahiro Nakayama, Tersuhiro Yoshinami, Fumie Fujisawa, Minako Nishio, Takashi Yamanaka, Toshinari Yamashita, Chiya Oshiro, Ayaka Izui, Nobumoto Tomioka, Hideki Maeda, Masafumi Shimoda, Kenzo Shimazu, Michiko Tsuneizumi, Ryoichi Matsunuma, Hiroko Bando, Aya Ueda, Hiroyuki Yasojima, Kumiko Okada, Kenichi Inoue, Yuichiro Kai, Katsuhide Yoshidome, Hidetoshi Kawaguchi, Masayuki Nagahashi, Kazuteru Oshima, Shinichiro Kashiwagi, Tsutomu Iwasa, Kanae Taruno, Shigeru Tsuyuki, Fumine Tsukamoto, Takashi Morimoto, Nobuyoshi Kittaka, Toru Higuchi, Yoichi Naito, Ryotaro Saita, Hiroyoshi Nishikawa, Daisuke Sugiyama, Yasuo Miyoshi, Yohei Uchida, Tomomi Yamada, Norikazu Masuda
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-06-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-06-04
Published: 02 May 2024
View article titled, Abstract PO2-06-04: Prospective study on eribulin efficacy in advanced and metastatic breast cancer: changes in TGF-β compared to other standard chemotherapy agents (KBCSG-TR 2018, POTENTIAL)
Journal Articles

Abstract PO3-13-04: The role of sphingolipids in cancer progression and its microenvironment in breast cancer patients

Akira Hattori, Masayuki Nagahashi, Aoi Oshiro, Ayumu Mitsuyoshi, Haruka Kanaoka, Ayako Bun, Reiko Fukui, Yukie Fujimoto, Tomoko Higuchi, Arisa Nishimukai, Keiko Murase, Yuichi Takatsuka, Yasuo Miyoshi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-13-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-13-04
Published: 02 May 2024
View article titled, Abstract PO3-13-04: The role of sphingolipids in cancer progression and its microenvironment in breast cancer patients
Journal Articles

Abstract 2032: Intratumoral tumor infiltrating lymphocytes is associated with cell proliferation and better survival but not with response to chemotherapy

Rongrong Wu, Masanori Oshi, Mariko Asaoka, Masayuki Nagahashi, Li Yan, Yasuo Miyoshi, Takashi Ishikawa, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2032.
https://doi.org/10.1158/1538-7445.AM2023-2032
Published: 04 April 2023
View article titled, Abstract 2032: Intratumoral tumor infiltrating lymphocytes is associated with cell proliferation and better survival but not with response to chemotherapy
Journal Articles

Abstract P5-12-02: Germline variants detected by next-generation sequencing-based multigene panel testing in patients with suspected hereditary breast cancer at a University Hospital in Japan

Yusa Atake, Masayuki Nagahashi, Haruka Kanaoka, Akira Hattori, Ayako Bun, Reiko Fukui, Hiromi Ozawa, Yukie Fujimoto, Tomoko Higuchi, Michiko Imamura, Keiko Murase, Yuichi Takatsuka, Mina Kashima, Chiho Okada, Chinatsu Kinjo, Mikako Miyata, Ayako Miyazaki, Mako Ueda, Hiroshi Tsubamoto, Hideaki Sawai, Yasuo Miyoshi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-12-02.
https://doi.org/10.1158/1538-7445.SABCS22-P5-12-02
Published: 01 March 2023
View article titled, Abstract P5-12-02: Germline variants detected by next-generation sequencing-based multigene panel testing in patients with suspected hereditary breast cancer at a University Hospital in Japan
Journal Articles

Abstract P2-20-12: Abundance of tumor-infiltrating lymphocytes is associated with pathologic complete response to neoadjuvant chemotherapy but not with survival in ER-positive/HER2-negative breast cancer

Rongrong Wu, Masayuki Nagahashi, Masanori Oshi, Yasuo Miyoshi, Takashi Ishikawa, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-20-12.
https://doi.org/10.1158/1538-7445.SABCS22-P2-20-12
Published: 01 March 2023
View article titled, Abstract P2-20-12: Abundance of tumor-infiltrating lymphocytes is associated with pathologic complete response to neoadjuvant chemotherapy but not with survival in ER-positive/HER2-negative breast cancer
Journal Articles

Abstract P2-11-28: Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients

Masayuki Nagahashi, Chie Toshikawa, YiWei Ling, Tetsu Hayashida, Yuko Kitagawa, Manabu Futamura, Takashi Kuwayama, Seigo Nakamura, Hideko Yamauchi, Teruo Yamauchi, Koji Kaneko, Chizuko Kanbayashi, Nobuaki Sato, Junko Tsuchida, Kazuki Moro, Masato Nakajima, Yoshifumi Shimada, Hiroshi Ichikawa, Stephen Lyle, Yasuo Miyoshi, Kazuaki Takabe, Shujiro Okuda, Toshifumi Wakai
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-11-28.
https://doi.org/10.1158/1538-7445.SABCS22-P2-11-28
Published: 01 March 2023
View article titled, Abstract P2-11-28: Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients
Journal Articles

Abstract P3-19-27: Prognostic impact of postmastectomy radiation therapy in breast cancer patients with T1, 2 and 1-3 lymph nodes from Japan Breast Cancer Registry

Akimitsu Yamada, Naoki Hayashi, Hiraku Kumamaru, Masayuki Nagahashi, Shiori Usune, Hiroaki Miyata, Takashi Ishikawa, Kazutaka Narui, Itaru Endo, Shigeru Imoto, Shinji Ohno, Hiromitsu Jinno
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-19-27.
https://doi.org/10.1158/1538-7445.SABCS21-P3-19-27
Published: 15 February 2022
View article titled, Abstract P3-19-27: Prognostic impact of postmastectomy radiation therapy in breast cancer patients with T1, 2 and 1-3 lymph nodes from Japan Breast Cancer Registry
Journal Articles

Abstract P4-07-26: Clinical impact of tumor infiltrating lymphocytes and neutrophil-lymphocyte ratio in estrogen receptor-positive/HER2-negative breast cancer patients with high 21-gene signature recurrence scores

Haruka Kanaoka, Masayuki Nagahashi, Eri Ishikawa, Ayako Bun, Reiko Fukui, Hiromi Ozawa, Tomoko Higuchi, Keiko Natori, Michiko Imamura, Yuichi Takatsuka, Yasuo Miyoshi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-07-26.
https://doi.org/10.1158/1538-7445.SABCS21-P4-07-26
Published: 15 February 2022
View article titled, Abstract P4-07-26: Clinical impact of tumor infiltrating lymphocytes and neutrophil-lymphocyte ratio in estrogen receptor-positive/HER2-negative breast cancer patients with high 21-gene signature recurrence scores
Journal Articles

Abstract PS7-79: Clinicopathological characteristics of male breast cancer in Japan from the national clinical database

Akihiko Shimomura, Masayuki Nagahashi, Hiraku Kumamaru, Yutaka Yamamoto, Hiromitsu Jinno, Shigeru Imoto, Registration Committee of Japan Breast Cancer Society
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS7-79.
https://doi.org/10.1158/1538-7445.SABCS20-PS7-79
Published: 15 February 2021
View article titled, Abstract PS7-79: Clinicopathological characteristics of male breast cancer in Japan from the national clinical database
Journal Articles

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

Masayuki Nagahashi, Akimitsu Yamada, Eriko Katsuta, Tomoyoshi Aoyagi, Wei-Ching Huang, Krista P. Terracina, Nitai C. Hait, Jeremy C. Allegood, Junko Tsuchida, Kizuki Yuza, Masato Nakajima, Manabu Abe, Kenji Sakimura, Sheldon Milstien, Toshifumi Wakai, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1713–1725.
https://doi.org/10.1158/0008-5472.CAN-17-1423
Published: 01 April 2018
View article titled, Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis
Open the PDF for Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 407: FTY720 suppressed CT26 murine colon cancer peritoneal carcinomatosis progression by decreasing tumor associated macrophages and TNF-alpha

Tomoyoshi Aoyagi, Dorit Avini, Masayuki Nagahashi, Akimitsu Yamada, Krista P. Terracina, Wei-Ching Huang, Kazunori Aoki, Yasunori Matsumoto, Sarah Spiegel, Hisahiro Matsubara, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 407.
https://doi.org/10.1158/1538-7445.AM2015-407
Published: 01 August 2015
View article titled, Abstract 407: FTY720 suppressed CT26 murine colon cancer peritoneal carcinomatosis progression by decreasing tumor associated macrophages and TNF-alpha
Journal Articles

Abstract 1890: Activated SphK1 and export of S1P via ABCC1 shorten disease free survival in breast cancer

Akimitsu Yamada, Masayuki Nagahashi, Tomoyoshi Aoyagi, Wei C. Huang, Krista P. Terracina, Jeremy C. Allegood, Santiago Lima, Sheldon Milstien, Sarah Spiegel, Kumiko Kida, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1890.
https://doi.org/10.1158/1538-7445.AM2014-1890
Published: 01 October 2014
View article titled, Abstract 1890: Activated SphK1 and export of S1P via ABCC1 shorten disease free survival in breast cancer
Journal Articles

Abstract 4884: Determination of sphingosine-1-phosphate levels in tissue interstitial fluid and lymphatic fluid utilizing novel collection techniques

Masayuki Nagahashi, Akimitsu Yamada, Hiroshi Miyazaki, Jeremy C. Allegood, Tomoyoshi Aoyagi, Wei-Ching Huang, Krista P. Terracina, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4884.
https://doi.org/10.1158/1538-7445.AM2014-4884
Published: 01 October 2014
View article titled, Abstract 4884: Determination of sphingosine-1-phosphate levels in tissue interstitial fluid and lymphatic fluid utilizing novel collection techniques
Journal Articles

Abstract 2695: FTY720 as a novel therapeutic approach for colon cancer carcinomatosis

Tomoyoshi Aoyagi, Dorit Avini, Masayuki Nagahashi, Akimitsu Yamada, Krista P. Terracina, Wei-Ching Huang, John Soong, Michael O. Idowu, Kazunori Aoki, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2695.
https://doi.org/10.1158/1538-7445.AM2014-2695
Published: 01 October 2014
View article titled, Abstract 2695: FTY720 as a novel therapeutic approach for colon cancer carcinomatosis
Journal Articles

Abstract 3280: The sphingosine-1-phosphate receptor modulator FTY720 synergistically inhibits colon cancer cell growth with 5-fluorouracil, irinotecan and oxaliplatin.

Tomoyoshi Aoyagi, Akimitsu Yamada, Masayuki Nagahashi, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3280.
https://doi.org/10.1158/1538-7445.AM2013-3280
Published: 15 April 2013
View article titled, Abstract 3280: The sphingosine-1-phosphate receptor modulator FTY720 synergistically inhibits colon cancer cell growth with 5-fluorouracil, irinotecan and oxaliplatin.
Journal Articles

Abstract 4887: FTY720 prevent tumorigenesis and suppress the progression of colitis-associated cancer.

Akimitsu Yamada, Jie Liang, Masayuki Nagahashi, Eugene Y. Kim, Kuzhuvelil B. Harikumar, Wei-Ching Huang, Nitai C. Hait, Jeremy C. Allegood, Megan M. Price, Dorit Avni, Tomasz Kordula, Milstien Sheldon, Kazuaki Takabe, Sarah Spiegel
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4887.
https://doi.org/10.1158/1538-7445.AM2013-4887
Published: 15 April 2013
View article titled, Abstract 4887: FTY720 prevent tumorigenesis and suppress the progression of colitis-associated cancer.
Journal Articles

Abstract 5000: Spinster 2 exports S1P, an important player in lymph node metastasis.

Masayuki Nagahashi, Eugene Y. Kim, Akimitsu Yamada, Subramaniam Ramachandran, Jeremy C. Allegood, Nitai Hait, Michael Maceyka, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5000.
https://doi.org/10.1158/1538-7445.AM2013-5000
Published: 15 April 2013
View article titled, Abstract 5000: Spinster 2 exports S1P, an important player in lymph node metastasis.
Journal Articles

Abstract LB-325: Sphingosine-1-phosphate links chronic intestinal inflammation to development of colitis-associated cancer.

Masayuki Nagahashi, Jie Liang, Eugene Y. Kim, Kuzhuvelil B. Harikumar, Akimitsu Yamada, Wei-Ching Huang, Nitai C. Hait, Jeremy C. Allegood, Megan M. Price, Dorit Avni, Kazuaki Takabe, Tomasz Kordula, Sheldon Milstien, Sarah Spiegel
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-325.
https://doi.org/10.1158/1538-7445.AM2013-LB-325
Published: 15 April 2013
View article titled, Abstract LB-325: Sphingosine-1-phosphate links chronic intestinal inflammation to development of colitis-associated cancer.
Journal Articles

Abstract 5280: Activation of sphingosine kinase 1 is necessary for angiopoietin 2-induced hemangiogenesis and lymphangiogenesis

Akimitsu Yamada, Masayuki Nagahashi, Subramaniam Ramachandran, Eugene Y. Kim, Jeremy C. Allegood, Omar M. Rashid, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5280.
https://doi.org/10.1158/1538-7445.AM2012-5280
Published: 15 April 2012
View article titled, Abstract 5280: Activation of sphingosine kinase 1 is necessary for angiopoietin 2-induced hemangiogenesis and lymphangiogenesis